Two polymorphic variants of ABCC1 selectively alter drug resistance and inhibitor sensitivity of the multidrug and organic anion transporter multidrug resistance protein 1

Drug Metabolism and Disposition

Volumn 41, Issue 12, 2013, Pages 2187-2196

  Conseil, Gwenaëlle ^a   Cole, Susan P C ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; ETOPOSIDE; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN 1; VINCRISTINE;

ABCC1 GENE; AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SENSITIVITY; EMBRYO; GENE; HUMAN; HUMAN CELL; NONSYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TRANSPORT; SINGLE NUCLEOTIDE POLYMORPHISM;

BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; COMPUTATIONAL BIOLOGY; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GLUTATHIONE; HEK293 CELLS; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PEPTIDE HYDROLASES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN TRANSPORT;

EID: 84888593742     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.054213     Document Type: Article

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