Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter

Biochemical Pharmacology

Volumn 75, Issue 8, 2008, Pages 1659-1669

  Létourneau, Isabelle J ^a   Nakajima, Akio ^a   Deeley, Roger G ^a   Cole, Susan P C ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Active transport; ATP binding and hydrolysis; ATP binding cassette; MRP1; Organic anion transport

Indexed keywords

ABC TRANSPORTER; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALANINE; ANION; ESTRADIOL DERIVATIVE; ESTRADIOL GLUCURONIDE; GLUCURONIDE; GLYCINE; ISOLEUCINE; LEUCINE; LEUKOTRIENE C4; MAGNESIUM ION; MEMBRANE PROTEIN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; NICKEL; NUCLEOTIDE; PHOSPHORUS 32; PHOSPHORUS 32 ALPHA; PHOSPHORUS 32 GAMMA; PROLINE; UNCLASSIFIED DRUG; VALINE; VANADIC ACID;

ACTIVE TRANSPORT; ALPHA HELIX; AMINO ACID SUBSTITUTION; ANION TRANSPORT; ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG TRANSPORT; ENZYME RELEASE; HUMAN; HUMAN CELL; HYDROLYSIS; LIGAND BINDING; LOW TEMPERATURE; PHENOTYPE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

CELL LINE; ESTRADIOL; HUMANS; LEUKOTRIENE C4; METHOTREXATE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTAGENESIS, SITE-DIRECTED; PROLINE; PROTEIN STRUCTURE, TERTIARY; TRANSFECTION; TRANSPORT VESICLES; TRYPSIN;

EID: 40949146910     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.01.009     Document Type: Article

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