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Volumn 27, Issue 4, 2013, Pages 409-425

Lymphovascular and neural regulation of metastasis: Shared tumour signalling pathways and novel therapeutic approaches

Author keywords

angiogenesis; beta blocker; lymphangiogenesis; nerve fibres; NSAID; SNS; sympathetic nervous system; vasculature

Indexed keywords

ACETYLSALICYLIC ACID; ADRENALIN; AFLIBERCEPT; ANGIOPOIETIN; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CELECOXIB; ETODOLAC; IBUPROFEN; INTEGRIN; KETOPROFEN; MATRIX METALLOPROTEINASE; NAPROXEN; PAZOPANIB; PLACENTAL GROWTH FACTOR; PROPRANOLOL; ROFECOXIB; SORAFENIB; SUNITINIB; VANDETANIB; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 3;

EID: 84888429760     PISSN: 15216896     EISSN: 1532169X     Source Type: Journal    
DOI: 10.1016/j.bpa.2013.10.008     Document Type: Review
Times cited : (13)

References (185)
  • 1
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • N.A. Bhowmick, E.G. Neilson, and H.L. Moses Stromal fibroblasts in cancer initiation and progression Nature (London) 432 7015 2004 332 337
    • (2004) Nature (London) , vol.432 , Issue.7015 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 2
    • 51349113366 scopus 로고    scopus 로고
    • Importance of Wnt signaling in the tumor stroma microenvironment
    • M.L. Macheda, and S.A. Stacker Importance of Wnt signaling in the tumor stroma microenvironment Curr Cancer Drug Targets 8 6 2008 454 465
    • (2008) Curr Cancer Drug Targets , vol.8 , Issue.6 , pp. 454-465
    • Macheda, M.L.1    Stacker, S.A.2
  • 3
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: Functions of cells recruited to the tumor microenvironment
    • D. Hanahan, and L.M. Coussens Accessories to the crime: functions of cells recruited to the tumor microenvironment Cancer Cell 21 3 2012 309 322
    • (2012) Cancer Cell , vol.21 , Issue.3 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 4
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 5 2011 646 674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 0041378074 scopus 로고    scopus 로고
    • Blood vessels and nerves: Common signals, pathways and diseases
    • P. Carmeliet Blood vessels and nerves: common signals, pathways and diseases Nat Rev Genet 4 9 2003 710 720
    • (2003) Nat Rev Genet , vol.4 , Issue.9 , pp. 710-720
    • Carmeliet, P.1
  • 6
    • 81255188905 scopus 로고    scopus 로고
    • The lymphatic vasculature in disease
    • K. Alitalo The lymphatic vasculature in disease Nature Med 17 11 2011 1371 1380
    • (2011) Nature Med , vol.17 , Issue.11 , pp. 1371-1380
    • Alitalo, K.1
  • 7
    • 13844265843 scopus 로고    scopus 로고
    • Focus on lymphangiogenesis in tumor metastasis
    • M.G. Achen, B.K. McColl, and S.A. Stacker Focus on lymphangiogenesis in tumor metastasis Cancer Cell 7 2 2005 121 127
    • (2005) Cancer Cell , vol.7 , Issue.2 , pp. 121-127
    • Achen, M.G.1    McColl, B.K.2    Stacker, S.A.3
  • 8
    • 34249689753 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis and lymphangiogenesis
    • R.H. Adams, and K. Alitalo Molecular regulation of angiogenesis and lymphangiogenesis Nature Rev Mol Cell Biol 8 6 2007 464 478
    • (2007) Nature Rev Mol Cell Biol , vol.8 , Issue.6 , pp. 464-478
    • Adams, R.H.1    Alitalo, K.2
  • 9
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • I.J. Fidler The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited Nature Rev Cancer 3 6 2003 453 458
    • (2003) Nature Rev Cancer , vol.3 , Issue.6 , pp. 453-458
    • Fidler, I.J.1
  • 10
    • 79952073341 scopus 로고    scopus 로고
    • The biology of cancer metastasis
    • I.J. Fidler The biology of cancer metastasis Semin Cancer Biol 21 2 2011 71
    • (2011) Semin Cancer Biol , vol.21 , Issue.2 , pp. 71
    • Fidler, I.J.1
  • 11
    • 84903880508 scopus 로고    scopus 로고
    • Vascular remodeling in cancer
    • 10.1038/onc.2013.304 [Epub ahead of print]
    • R.H. Farnsworth, M. Lackmann, and M.G. Achen Vascular remodeling in cancer Oncogene 2013, Aug 5 10.1038/onc.2013.304 [Epub ahead of print]
    • (2013) Oncogene
    • Farnsworth, R.H.1    Lackmann, M.2    Achen, M.G.3
  • 12
    • 0036673666 scopus 로고    scopus 로고
    • Lymphangiogenesis and cancer metastasis
    • S.A. Stacker Lymphangiogenesis and cancer metastasis Nat Rev Cancer 2 2002 573 583
    • (2002) Nat Rev Cancer , vol.2 , pp. 573-583
    • Stacker, S.A.1
  • 13
    • 84863011445 scopus 로고    scopus 로고
    • VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium
    • T. Karnezis VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium Cancer Cell 21 2 2012 181 195
    • (2012) Cancer Cell , vol.21 , Issue.2 , pp. 181-195
    • Karnezis, T.1
  • 14
    • 84888434134 scopus 로고
    • Official medical experts
    • W.M. Cannon Official medical experts Cal State J Med 13 1 1915 13 15
    • (1915) Cal State J Med , vol.13 , Issue.1 , pp. 13-15
    • Cannon, W.M.1
  • 15
    • 34548096953 scopus 로고    scopus 로고
    • Social stress enhances sympathetic innervation of primate lymph nodes: Mechanisms and implications for viral pathogenesis
    • E.K. Sloan Social stress enhances sympathetic innervation of primate lymph nodes: mechanisms and implications for viral pathogenesis J Neurosci 27 33 2007 8857 8865
    • (2007) J Neurosci , vol.27 , Issue.33 , pp. 8857-8865
    • Sloan, E.K.1
  • 16
    • 82955197460 scopus 로고    scopus 로고
    • Alpha- and beta-adrenergic receptor (AR) protein expression is associated with poor clinical outcome in breast cancer: An immunohistochemical study
    • D.G. Powe Alpha- and beta-adrenergic receptor (AR) protein expression is associated with poor clinical outcome in breast cancer: an immunohistochemical study Breast Cancer Res Treat 130 2011 457 463
    • (2011) Breast Cancer Res Treat , vol.130 , pp. 457-463
    • Powe, D.G.1
  • 17
    • 78650987645 scopus 로고    scopus 로고
    • The beta2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells
    • M. Shi The beta2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells Breast Cancer Res Treat 125 2 2011 351 362
    • (2011) Breast Cancer Res Treat , vol.125 , Issue.2 , pp. 351-362
    • Shi, M.1
  • 18
    • 84874595409 scopus 로고    scopus 로고
    • Beta-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines
    • S. Moretti Beta-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines Lab Invest 93 3 2013 279 290
    • (2013) Lab Invest , vol.93 , Issue.3 , pp. 279-290
    • Moretti, S.1
  • 19
    • 58549084362 scopus 로고    scopus 로고
    • Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: Implications for stress-related enhancement of tumor progression
    • E.V. Yang Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression Brain Behav Immun 23 2 2009 267 275
    • (2009) Brain Behav Immun , vol.23 , Issue.2 , pp. 267-275
    • Yang, E.V.1
  • 20
    • 77956931932 scopus 로고    scopus 로고
    • The sympathetic nervous system induces a metastatic switch in primary breast cancer
    • E.K. Sloan The sympathetic nervous system induces a metastatic switch in primary breast cancer Cancer Res 70 18 2010 7042 7052
    • (2010) Cancer Res , vol.70 , Issue.18 , pp. 7042-7052
    • Sloan, E.K.1
  • 21
    • 84864418995 scopus 로고    scopus 로고
    • Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice
    • J.P. Campbell Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice PLoS Biol 10 7 2012 e1001363
    • (2012) PLoS Biol , vol.10 , Issue.7 , pp. 1001363
    • Campbell, J.P.1
  • 22
    • 0025744988 scopus 로고
    • Stress increases metastatic spread of a mammary tumor in rats: Evidence for mediation by the immune system
    • S. Ben-Eliyahu Stress increases metastatic spread of a mammary tumor in rats: evidence for mediation by the immune system Brain Behav Immun 5 2 1991 193 205
    • (1991) Brain Behav Immun , vol.5 , Issue.2 , pp. 193-205
    • Ben-Eliyahu, S.1
  • 23
    • 0034532188 scopus 로고    scopus 로고
    • Suppression of NK cell activity and of resistance to metastasis by stress: A role for adrenal catecholamines and beta-adrenoceptors
    • S. Ben-Eliyahu Suppression of NK cell activity and of resistance to metastasis by stress: a role for adrenal catecholamines and beta-adrenoceptors Neuroimmunomodulation 8 3 2000 154 164
    • (2000) Neuroimmunomodulation , vol.8 , Issue.3 , pp. 154-164
    • Ben-Eliyahu, S.1
  • 24
    • 33746851955 scopus 로고    scopus 로고
    • Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
    • P.H. Thaker Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma Nat Med 12 8 2006 939 944
    • (2006) Nat Med , vol.12 , Issue.8 , pp. 939-944
    • Thaker, P.H.1
  • 25
    • 84880279713 scopus 로고    scopus 로고
    • Autonomic nerve development contributes to prostate cancer progression
    • C. Magnon Autonomic nerve development contributes to prostate cancer progression Science 341 6142 2013 1236361
    • (2013) Science , vol.341 , Issue.6142 , pp. 1236361
    • Magnon, C.1
  • 26
    • 84873358810 scopus 로고    scopus 로고
    • Behavioral stress accelerates prostate cancer development in mice
    • S. Hassan Behavioral stress accelerates prostate cancer development in mice J Clin Invest 123 2 2013 874 886
    • (2013) J Clin Invest , vol.123 , Issue.2 , pp. 874-886
    • Hassan, S.1
  • 27
    • 33646371479 scopus 로고    scopus 로고
    • The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers
    • D. Palm The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers Int J Cancer 118 11 2006 2744 2749
    • (2006) Int J Cancer , vol.118 , Issue.11 , pp. 2744-2749
    • Palm, D.1
  • 28
    • 84859426449 scopus 로고    scopus 로고
    • Chronic stress enhances progression of acute lymphoblastic leukemia via beta-adrenergic signaling
    • D.M. Lamkin Chronic stress enhances progression of acute lymphoblastic leukemia via beta-adrenergic signaling Brain Behav Immun 26 4 2012 635 641
    • (2012) Brain Behav Immun , vol.26 , Issue.4 , pp. 635-641
    • Lamkin, D.M.1
  • 29
    • 79955776345 scopus 로고    scopus 로고
    • Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity
    • S. Inbar Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity PLoS One 6 4 2011 e19246
    • (2011) PLoS One , vol.6 , Issue.4 , pp. 19246
    • Inbar, S.1
  • 30
    • 84859922249 scopus 로고    scopus 로고
    • Involvement of alpha2- and beta2-adrenoceptors on breast cancer cell proliferation and tumour growth regulation
    • C. Perez Pinero Involvement of alpha2- and beta2-adrenoceptors on breast cancer cell proliferation and tumour growth regulation Br J Pharmacol 166 2 2012 721 736
    • (2012) Br J Pharmacol , vol.166 , Issue.2 , pp. 721-736
    • Perez Pinero, C.1
  • 31
    • 46149121727 scopus 로고    scopus 로고
    • Perioperative use of beta-blockers and COX-2 inhibitors may improve immune competence and reduce the risk of tumor metastasis
    • M. Benish Perioperative use of beta-blockers and COX-2 inhibitors may improve immune competence and reduce the risk of tumor metastasis Ann Surg Oncol 15 7 2008 2042 2052
    • (2008) Ann Surg Oncol , vol.15 , Issue.7 , pp. 2042-2052
    • Benish, M.1
  • 32
    • 48649108278 scopus 로고    scopus 로고
    • Do stress-related psychosocial factors contribute to cancer incidence and survival?
    • Y. Chida, M. Hamer, and J. Wardle Do stress-related psychosocial factors contribute to cancer incidence and survival? Nat Clin Pract Oncol 5 8 2008 466 475
    • (2008) Nat Clin Pract Oncol , vol.5 , Issue.8 , pp. 466-475
    • Chida, Y.1    Hamer, M.2    Wardle, J.3
  • 33
    • 33644989152 scopus 로고    scopus 로고
    • Social networks, social support, and survival after breast cancer diagnosis
    • C.H. Kroenke Social networks, social support, and survival after breast cancer diagnosis J Clin Oncol 24 7 2006 1105 1111
    • (2006) J Clin Oncol , vol.24 , Issue.7 , pp. 1105-1111
    • Kroenke, C.H.1
  • 34
    • 0034669336 scopus 로고    scopus 로고
    • Use of coping strategies and breast cancer survival: Results from the Black/White Cancer Survival Study
    • P. Reynolds Use of coping strategies and breast cancer survival: results from the Black/White Cancer Survival Study Am J Epidemiol 152 10 2000 940 949
    • (2000) Am J Epidemiol , vol.152 , Issue.10 , pp. 940-949
    • Reynolds, P.1
  • 35
    • 0026648353 scopus 로고
    • Social relations, social support and survival among patients with cancer
    • K. Ell Social relations, social support and survival among patients with cancer J Psychosom Res 36 6 1992 531 541
    • (1992) J Psychosom Res , vol.36 , Issue.6 , pp. 531-541
    • Ell, K.1
  • 36
    • 0041916159 scopus 로고    scopus 로고
    • Prognostic significance of psychosocial factors in African-American and white breast cancer patients: A population-based study
    • H. Soler-Vila, S.V. Kasl, and B.A. Jones Prognostic significance of psychosocial factors in African-American and white breast cancer patients: a population-based study Cancer 98 6 2003 1299 1308
    • (2003) Cancer , vol.98 , Issue.6 , pp. 1299-1308
    • Soler-Vila, H.1    Kasl, S.V.2    Jones, B.A.3
  • 37
    • 0026563017 scopus 로고
    • Life events and breast cancer prognosis
    • J. Barraclough Life events and breast cancer prognosis BMJ 304 6834 1992 1078 1081
    • (1992) BMJ , vol.304 , Issue.6834 , pp. 1078-1081
    • Barraclough, J.1
  • 38
    • 0037097725 scopus 로고    scopus 로고
    • Stressful life experiences and risk of relapse of breast cancer: Observational cohort study
    • J. Graham Stressful life experiences and risk of relapse of breast cancer: observational cohort study BMJ 324 7351 2002 1420
    • (2002) BMJ , vol.324 , Issue.7351 , pp. 1420
    • Graham, J.1
  • 39
    • 77953713557 scopus 로고    scopus 로고
    • Biobehavioral, immune, and health benefits following recurrence for psychological intervention participants
    • B.L. Andersen Biobehavioral, immune, and health benefits following recurrence for psychological intervention participants Clin Cancer Res 16 12 2010 3270 3278
    • (2010) Clin Cancer Res , vol.16 , Issue.12 , pp. 3270-3278
    • Andersen, B.L.1
  • 40
    • 57649123246 scopus 로고    scopus 로고
    • Psychologic intervention improves survival for breast cancer patients: A randomized clinical trial
    • B.L. Andersen Psychologic intervention improves survival for breast cancer patients: a randomized clinical trial Cancer 113 12 2008 3450 3458
    • (2008) Cancer , vol.113 , Issue.12 , pp. 3450-3458
    • Andersen, B.L.1
  • 41
    • 0037371085 scopus 로고    scopus 로고
    • Stressful life events and risk of breast cancer in 10,808 women: A cohort study
    • K. Lillberg Stressful life events and risk of breast cancer in 10,808 women: a cohort study Am J Epidemiol 157 5 2003 415 423
    • (2003) Am J Epidemiol , vol.157 , Issue.5 , pp. 415-423
    • Lillberg, K.1
  • 42
    • 0022637281 scopus 로고
    • Bereavement and breast cancer
    • M. Ewertz Bereavement and breast cancer Br J Cancer 53 5 1986 701 703
    • (1986) Br J Cancer , vol.53 , Issue.5 , pp. 701-703
    • Ewertz, M.1
  • 43
    • 0033795302 scopus 로고    scopus 로고
    • Cancer incidence and survival following bereavement
    • I. Levav Cancer incidence and survival following bereavement Am J Public Health 90 10 2000 1601 1607
    • (2000) Am J Public Health , vol.90 , Issue.10 , pp. 1601-1607
    • Levav, I.1
  • 44
    • 0031030736 scopus 로고    scopus 로고
    • Psychological stress, cancer incidence and mortality from non-malignant diseases
    • C. Johansen, and J.H. Olsen Psychological stress, cancer incidence and mortality from non-malignant diseases Br J Cancer 75 1 1997 144 148
    • (1997) Br J Cancer , vol.75 , Issue.1 , pp. 144-148
    • Johansen, C.1    Olsen, J.H.2
  • 45
    • 0028031304 scopus 로고
    • Widowhood and divorce related to cancer risk in middle-aged women. A nested case-control study among Norwegian women born between 1935 and 1954
    • A. Kvikstad Widowhood and divorce related to cancer risk in middle-aged women. A nested case-control study among Norwegian women born between 1935 and 1954 Int J Cancer 58 4 1994 512 516
    • (1994) Int J Cancer , vol.58 , Issue.4 , pp. 512-516
    • Kvikstad, A.1
  • 46
    • 76849095665 scopus 로고    scopus 로고
    • The role of COX-2 in intestinal inflammation and colorectal cancer
    • D. Wang, and R.N. Dubois The role of COX-2 in intestinal inflammation and colorectal cancer Oncogene 29 6 2010 781 788
    • (2010) Oncogene , vol.29 , Issue.6 , pp. 781-788
    • Wang, D.1    Dubois, R.N.2
  • 47
    • 47749150261 scopus 로고    scopus 로고
    • Cancer and inflammation: A complex relationship
    • A. Mantovani, and M.A. Pierotti Cancer and inflammation: a complex relationship Cancer Lett 267 2 2008 180 181
    • (2008) Cancer Lett , vol.267 , Issue.2 , pp. 180-181
    • Mantovani, A.1    Pierotti, M.A.2
  • 48
    • 81255188940 scopus 로고    scopus 로고
    • Tumor angiogenesis: Molecular pathways and therapeutic targets
    • S.M. Weis, and D.A. Cheresh Tumor angiogenesis: molecular pathways and therapeutic targets Nat Med 17 11 2011 1359 1370
    • (2011) Nat Med , vol.17 , Issue.11 , pp. 1359-1370
    • Weis, S.M.1    Cheresh, D.A.2
  • 49
    • 66349093990 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • N. Ferrara Vascular endothelial growth factor Arterioscler Thromb Vasc Biol 29 6 2009 789 791
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.6 , pp. 789-791
    • Ferrara, N.1
  • 50
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • B. Millauer High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis Cell 72 1993 835 846
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1
  • 51
    • 78650424066 scopus 로고    scopus 로고
    • Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
    • C. Gialeli, A.D. Theocharis, and N.K. Karamanos Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting FEBS J 278 1 2011 16 27
    • (2011) FEBS J , vol.278 , Issue.1 , pp. 16-27
    • Gialeli, C.1    Theocharis, A.D.2    Karamanos, N.K.3
  • 52
    • 0035793037 scopus 로고    scopus 로고
    • Disruption of matrix metalloproteinase 2 binding to integrin à v á 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo
    • S. Silletti Disruption of matrix metalloproteinase 2 binding to integrin à v á 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo Proc Natl Acad Sci U.S.A 98 1 2001 119 124
    • (2001) Proc Natl Acad Sci U.S.A , vol.98 , Issue.1 , pp. 119-124
    • Silletti, S.1
  • 53
    • 84868618772 scopus 로고    scopus 로고
    • Notch signaling in developmental and tumor angiogenesis
    • N.M. Kofler Notch signaling in developmental and tumor angiogenesis Genes Cancer 2 12 2011 1106 1116
    • (2011) Genes Cancer , vol.2 , Issue.12 , pp. 1106-1116
    • Kofler, N.M.1
  • 54
    • 0345798150 scopus 로고    scopus 로고
    • Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
    • A. Abramsson, P. Lindblom, and C. Betsholtz Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors J Clin Invest 112 8 2003 1142 1151
    • (2003) J Clin Invest , vol.112 , Issue.8 , pp. 1142-1151
    • Abramsson, A.1    Lindblom, P.2    Betsholtz, C.3
  • 55
    • 84859415553 scopus 로고    scopus 로고
    • Molecular pathways: Fibroblast growth factor signaling: A new therapeutic opportunity in cancer
    • A.N. Brooks, E. Kilgour, and P.D. Smith Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer Clin Cancer Res 18 7 2012 1855 1862
    • (2012) Clin Cancer Res , vol.18 , Issue.7 , pp. 1855-1862
    • Brooks, A.N.1    Kilgour, E.2    Smith, P.D.3
  • 56
    • 35548982639 scopus 로고    scopus 로고
    • Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels
    • C. Fischer Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels Cell 131 3 2007 463 475
    • (2007) Cell , vol.131 , Issue.3 , pp. 463-475
    • Fischer, C.1
  • 57
    • 84874760414 scopus 로고    scopus 로고
    • Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma
    • M. Snuderl Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma Cell 152 5 2013 1065 1076
    • (2013) Cell , vol.152 , Issue.5 , pp. 1065-1076
    • Snuderl, M.1
  • 58
    • 84875456598 scopus 로고    scopus 로고
    • Angiopoietin-2: An attractive target for improved antiangiogenic tumor therapy
    • D. Gerald Angiopoietin-2: an attractive target for improved antiangiogenic tumor therapy Cancer Res 73 6 2013 1649 1657
    • (2013) Cancer Res , vol.73 , Issue.6 , pp. 1649-1657
    • Gerald, D.1
  • 59
    • 18844471324 scopus 로고    scopus 로고
    • Vascular endothelial growth factors VEGF-B and VEGF-C are expressed in human tumors
    • P. Salven Vascular endothelial growth factors VEGF-B and VEGF-C are expressed in human tumors Am J Pathol 153 1998 103 108
    • (1998) Am J Pathol , vol.153 , pp. 103-108
    • Salven, P.1
  • 60
    • 0032933883 scopus 로고    scopus 로고
    • VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
    • R. Valtola VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer Am J Pathol 154 5 1999 1381 1390
    • (1999) Am J Pathol , vol.154 , Issue.5 , pp. 1381-1390
    • Valtola, R.1
  • 61
    • 0034842967 scopus 로고    scopus 로고
    • Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma
    • M. Skobe Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma Am J Pathol 159 3 2001 893 903
    • (2001) Am J Pathol , vol.159 , Issue.3 , pp. 893-903
    • Skobe, M.1
  • 62
    • 0035126049 scopus 로고    scopus 로고
    • VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
    • S.A. Stacker VEGF-D promotes the metastatic spread of tumor cells via the lymphatics Nature Med 7 2 2001 186 191
    • (2001) Nature Med , vol.7 , Issue.2 , pp. 186-191
    • Stacker, S.A.1
  • 63
    • 0035718735 scopus 로고    scopus 로고
    • VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme
    • W. Debinski VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme Mol Med 7 2001 598 608
    • (2001) Mol Med , vol.7 , pp. 598-608
    • Debinski, W.1
  • 64
    • 0141621049 scopus 로고    scopus 로고
    • Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens
    • L.M. Wise Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens J Biol Chem 278 39 2003 38004 38014
    • (2003) J Biol Chem , vol.278 , Issue.39 , pp. 38004-38014
    • Wise, L.M.1
  • 65
    • 0033527634 scopus 로고    scopus 로고
    • Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers
    • S.A. Stacker Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers J Biol Chem 274 45 1999 32127 32136
    • (1999) J Biol Chem , vol.274 , Issue.45 , pp. 32127-32136
    • Stacker, S.A.1
  • 66
    • 0031011529 scopus 로고    scopus 로고
    • Proteolytic processing regulates receptor specificity and activity of VEGF-C
    • V. Joukov Proteolytic processing regulates receptor specificity and activity of VEGF-C EMBO J 16 1997 3898 3911
    • (1997) EMBO J , vol.16 , pp. 3898-3911
    • Joukov, V.1
  • 67
    • 0141672945 scopus 로고    scopus 로고
    • Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D
    • B.K. McColl Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D J Exp Med 198 6 2003 863 868
    • (2003) J Exp Med , vol.198 , Issue.6 , pp. 863-868
    • McColl, B.K.1
  • 68
    • 33947670424 scopus 로고    scopus 로고
    • Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2
    • B.K. McColl Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2 FASEB J 21 4 2007 1088 1098
    • (2007) FASEB J , vol.21 , Issue.4 , pp. 1088-1098
    • McColl, B.K.1
  • 69
    • 0035941203 scopus 로고    scopus 로고
    • Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis
    • M.E. Baldwin Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis J Biol Chem 276 47 2001 44307 44314
    • (2001) J Biol Chem , vol.276 , Issue.47 , pp. 44307-44314
    • Baldwin, M.E.1
  • 70
    • 0030026897 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt-4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
    • V. Joukov A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt-4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases EMBO J 15 2 1996 290 298
    • (1996) EMBO J , vol.15 , Issue.2 , pp. 290-298
    • Joukov, V.1
  • 71
    • 0031905861 scopus 로고    scopus 로고
    • Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
    • M.G. Achen Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4) Proc Natl Acad Sci U.S.A 95 2 1998 548 553
    • (1998) Proc Natl Acad Sci U.S.A , vol.95 , Issue.2 , pp. 548-553
    • Achen, M.G.1
  • 72
    • 17744396472 scopus 로고    scopus 로고
    • Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
    • T. Veikkola Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice EMBO J 20 6 2001 1223 1231
    • (2001) EMBO J , vol.20 , Issue.6 , pp. 1223-1231
    • Veikkola, T.1
  • 73
    • 0030973506 scopus 로고    scopus 로고
    • Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
    • M. Jeltsch Hyperplasia of lymphatic vessels in VEGF-C transgenic mice Science 276 1997 1423 1425
    • (1997) Science , vol.276 , pp. 1423-1425
    • Jeltsch, M.1
  • 74
    • 34250370123 scopus 로고    scopus 로고
    • Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
    • M. Wirzenius Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting J Exp Med 204 6 2007 1431 1440
    • (2007) J Exp Med , vol.204 , Issue.6 , pp. 1431-1440
    • Wirzenius, M.1
  • 75
    • 17744390184 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
    • S.J. Mandriota Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis EMBO J 20 4 2001 672 682
    • (2001) EMBO J , vol.20 , Issue.4 , pp. 672-682
    • Mandriota, S.J.1
  • 76
    • 34247892352 scopus 로고    scopus 로고
    • Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis
    • L. Kopfstein Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis Am J Pathol 170 4 2007 1348 1361
    • (2007) Am J Pathol , vol.170 , Issue.4 , pp. 1348-1361
    • Kopfstein, L.1
  • 77
    • 84880456245 scopus 로고    scopus 로고
    • Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis
    • A. Gogineni Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis PLoS One 8 7 2013 e68755
    • (2013) PLoS One , vol.8 , Issue.7 , pp. 68755
    • Gogineni, A.1
  • 78
    • 10344237560 scopus 로고    scopus 로고
    • Lymphangiogenic growth factors as markers of tumor metastasis
    • S.A. Stacker, R.A. Williams, and M.G. Achen Lymphangiogenic growth factors as markers of tumor metastasis APMIS 112 2004 539 549
    • (2004) APMIS , vol.112 , pp. 539-549
    • Stacker, S.A.1    Williams, R.A.2    Achen, M.G.3
  • 79
    • 27744441516 scopus 로고    scopus 로고
    • Lymphatic endothelium: An important interactive surface for malignant cells
    • R.H. Farnsworth, M.G. Achen, and S.A. Stacker Lymphatic endothelium: an important interactive surface for malignant cells Pulm Pharmacol Ther 19 1 2006 51 60
    • (2006) Pulm Pharmacol Ther , vol.19 , Issue.1 , pp. 51-60
    • Farnsworth, R.H.1    Achen, M.G.2    Stacker, S.A.3
  • 80
    • 33846857321 scopus 로고    scopus 로고
    • VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
    • S. Hirakawa VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites Blood 109 3 2007 1010 1017
    • (2007) Blood , vol.109 , Issue.3 , pp. 1010-1017
    • Hirakawa, S.1
  • 81
    • 33646835413 scopus 로고    scopus 로고
    • Targeting lymphangiogenesis to prevent tumour metastasis
    • M.G. Achen, G.B. Mann, and S.A. Stacker Targeting lymphangiogenesis to prevent tumour metastasis Br J Cancer 94 10 2006 1355 1360
    • (2006) Br J Cancer , vol.94 , Issue.10 , pp. 1355-1360
    • Achen, M.G.1    Mann, G.B.2    Stacker, S.A.3
  • 82
    • 58149088898 scopus 로고    scopus 로고
    • From anti-angiogenesis to anti-lymphangiogenesis: Emerging trends in cancer therapy
    • S.A. Stacker, and M.G. Achen From anti-angiogenesis to anti-lymphangiogenesis: emerging trends in cancer therapy Lymphat Res Biol 6 3-4 2008 165 172
    • (2008) Lymphat Res Biol , vol.6 , Issue.34 , pp. 165-172
    • Stacker, S.A.1    Achen, M.G.2
  • 83
    • 44449133602 scopus 로고    scopus 로고
    • Molecular control of lymphatic metastasis
    • M.G. Achen, and S.A. Stacker Molecular control of lymphatic metastasis Ann N Y Acad Sci 1131 2008 225 234
    • (2008) Ann N y Acad Sci , vol.1131 , pp. 225-234
    • Achen, M.G.1    Stacker, S.A.2
  • 84
    • 79958241544 scopus 로고    scopus 로고
    • Lymphatic vascular morphogenesis in development, physiology, and disease
    • S. Schulte-Merker, A. Sabine, and T.V. Petrova Lymphatic vascular morphogenesis in development, physiology, and disease J Cell Biol 193 4 2011 607 618
    • (2011) J Cell Biol , vol.193 , Issue.4 , pp. 607-618
    • Schulte-Merker, S.1    Sabine, A.2    Petrova, T.V.3
  • 85
    • 76749083490 scopus 로고    scopus 로고
    • Lymphangiogenesis: Molecular mechanisms and future promise
    • T. Tammela, and K. Alitalo Lymphangiogenesis: molecular mechanisms and future promise Cell 140 4 2010 460 476
    • (2010) Cell , vol.140 , Issue.4 , pp. 460-476
    • Tammela, T.1    Alitalo, K.2
  • 86
    • 79959863771 scopus 로고    scopus 로고
    • Erythropoietin induces lymph node lymphangiogenesis and lymph node tumor metastasis
    • A.S. Lee Erythropoietin induces lymph node lymphangiogenesis and lymph node tumor metastasis Cancer Res 71 13 2011 4506 4517
    • (2011) Cancer Res , vol.71 , Issue.13 , pp. 4506-4517
    • Lee, A.S.1
  • 87
    • 84873452261 scopus 로고    scopus 로고
    • Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis
    • N.O. Karpinich Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis FASEB J 27 2 2013 590 600
    • (2013) FASEB J , vol.27 , Issue.2 , pp. 590-600
    • Karpinich, N.O.1
  • 88
    • 0031844535 scopus 로고    scopus 로고
    • The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers
    • R.N. DuBois The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers Carcinogenesis 19 1 1998 49 53
    • (1998) Carcinogenesis , vol.19 , Issue.1 , pp. 49-53
    • Dubois, R.N.1
  • 89
    • 84858326048 scopus 로고    scopus 로고
    • Prostaglandins in cancer cell adhesion, migration, and invasion
    • D.G. Menter, and R.N. Dubois Prostaglandins in cancer cell adhesion, migration, and invasion Int J Cell Biol 2012 2012 723419
    • (2012) Int J Cell Biol , vol.2012 , pp. 723419
    • Menter, D.G.1    Dubois, R.N.2
  • 90
    • 0023915232 scopus 로고
    • Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence
    • C. Yokoyama, T. Takai, and T. Tanabe Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence FEBS Lett 231 2 1988 347 351
    • (1988) FEBS Lett , vol.231 , Issue.2 , pp. 347-351
    • Yokoyama, C.1    Takai, T.2    Tanabe, T.3
  • 91
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • D.A. Kujubu TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue J Biol Chem 266 20 1991 12866 12872
    • (1991) J Biol Chem , vol.266 , Issue.20 , pp. 12866-12872
    • Kujubu, D.A.1
  • 92
    • 0026730021 scopus 로고
    • Human cyclooxygenase-2 cDNA
    • T. Hla, and K. Neilson Human cyclooxygenase-2 cDNA Proc Natl Acad Sci U S A 89 16 1992 7384 7388
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.16 , pp. 7384-7388
    • Hla, T.1    Neilson, K.2
  • 93
    • 0028120558 scopus 로고
    • Insulin sensitivity of adipocytes from inbred mouse strains resistant or sensitive to diet-induced obesity
    • G.P. Eberhart Insulin sensitivity of adipocytes from inbred mouse strains resistant or sensitive to diet-induced obesity Am J Physiol 266 5 Pt 2 1994 R1423 R1428
    • (1994) Am J Physiol , vol.266 , Issue.5 PART 2
    • Eberhart, G.P.1
  • 94
    • 0029117472 scopus 로고
    • Expression of cyclooxygenase-1 and -2 in human colorectal cancer
    • H. Sano Expression of cyclooxygenase-1 and -2 in human colorectal cancer Cancer Res 55 17 1995 3785 3789
    • (1995) Cancer Res , vol.55 , Issue.17 , pp. 3785-3789
    • Sano, H.1
  • 95
    • 0032170955 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas
    • T. Hida Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas Cancer Res 58 17 1998 3761 3764
    • (1998) Cancer Res , vol.58 , Issue.17 , pp. 3761-3764
    • Hida, T.1
  • 96
    • 0032542763 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer
    • D. Hwang Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer J Natl Cancer Inst 90 6 1998 455 460
    • (1998) J Natl Cancer Inst , vol.90 , Issue.6 , pp. 455-460
    • Hwang, D.1
  • 97
    • 0033106051 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer
    • O.N. Tucker Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer Cancer Res 59 5 1999 987 990
    • (1999) Cancer Res , vol.59 , Issue.5 , pp. 987-990
    • Tucker, O.N.1
  • 98
    • 0033105360 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck
    • G. Chan Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck Cancer Res 59 5 1999 991 994
    • (1999) Cancer Res , vol.59 , Issue.5 , pp. 991-994
    • Chan, G.1
  • 99
    • 0037769698 scopus 로고    scopus 로고
    • Structure and function of human NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase
    • H.H. Tai Structure and function of human NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase Adv Exp Med Biol 507 2002 245 250
    • (2002) Adv Exp Med Biol , vol.507 , pp. 245-250
    • Tai, H.H.1
  • 100
    • 26444543238 scopus 로고    scopus 로고
    • Mechanisms for the prevention of gastrointestinal cancer: The role of prostaglandin E2
    • M.G. Backlund, J.R. Mann, and R.N. Dubois Mechanisms for the prevention of gastrointestinal cancer: the role of prostaglandin E2 Oncology 69 Suppl. 1 2005 28 32
    • (2005) Oncology , vol.69 , Issue.SUPPL. 1 , pp. 28-32
    • Backlund, M.G.1    Mann, J.R.2    Dubois, R.N.3
  • 101
    • 10644274362 scopus 로고    scopus 로고
    • 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers
    • M. Yan 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers Proc Natl Acad Sci U S A 101 50 2004 17468 17473
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.50 , pp. 17468-17473
    • Yan, M.1
  • 102
    • 33747873279 scopus 로고    scopus 로고
    • 15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer
    • I. Wolf 15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer Cancer Res 66 15 2006 7818 7823
    • (2006) Cancer Res , vol.66 , Issue.15 , pp. 7818-7823
    • Wolf, I.1
  • 103
    • 0027371123 scopus 로고
    • Altered eicosanoid levels in human colon cancer
    • B. Rigas, I.S. Goldman, and L. Levine Altered eicosanoid levels in human colon cancer J Lab Clin Med 122 5 1993 518 523
    • (1993) J Lab Clin Med , vol.122 , Issue.5 , pp. 518-523
    • Rigas, B.1    Goldman, I.S.2    Levine, L.3
  • 104
    • 0028261042 scopus 로고
    • Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2
    • S. Pugh, and G.A. Thomas Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2 Gut 35 5 1994 675 678
    • (1994) Gut , vol.35 , Issue.5 , pp. 675-678
    • Pugh, S.1    Thomas, G.A.2
  • 105
    • 62349138124 scopus 로고    scopus 로고
    • The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
    • A. Greenhough The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment Carcinogenesis 30 3 2009 377 386
    • (2009) Carcinogenesis , vol.30 , Issue.3 , pp. 377-386
    • Greenhough, A.1
  • 106
    • 0034796261 scopus 로고    scopus 로고
    • Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice
    • M. Sonoshita Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice Nat Med 7 9 2001 1048 1051
    • (2001) Nat Med , vol.7 , Issue.9 , pp. 1048-1051
    • Sonoshita, M.1
  • 107
    • 0036142927 scopus 로고    scopus 로고
    • Involvement of prostaglandin e receptor subtype EP(4) in colon carcinogenesis
    • M. Mutoh Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis Cancer Res 62 1 2002 28 32
    • (2002) Cancer Res , vol.62 , Issue.1 , pp. 28-32
    • Mutoh, M.1
  • 108
    • 0037454960 scopus 로고    scopus 로고
    • Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth
    • H. Amano Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth J Exp Med 197 2 2003 221 232
    • (2003) J Exp Med , vol.197 , Issue.2 , pp. 221-232
    • Amano, H.1
  • 109
    • 33750548053 scopus 로고    scopus 로고
    • Targeting prostaglandin e EP receptors to inhibit metastasis
    • A.M. Fulton, X. Ma, and N. Kundu Targeting prostaglandin E EP receptors to inhibit metastasis Cancer Res 66 20 2006 9794 9797
    • (2006) Cancer Res , vol.66 , Issue.20 , pp. 9794-9797
    • Fulton, A.M.1    Ma, X.2    Kundu, N.3
  • 110
    • 18744435476 scopus 로고    scopus 로고
    • Inhibitory effect of a prostaglandin e receptor subtype EP(1) selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in mice
    • K. Watanabe Inhibitory effect of a prostaglandin E receptor subtype EP(1) selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in mice Cancer Lett 156 1 2000 57 61
    • (2000) Cancer Lett , vol.156 , Issue.1 , pp. 57-61
    • Watanabe, K.1
  • 111
    • 82355182118 scopus 로고    scopus 로고
    • Prostaglandin E(2) (PGE (2)) suppresses natural killer cell function primarily through the PGE(2) receptor EP4
    • D. Holt Prostaglandin E(2) (PGE (2)) suppresses natural killer cell function primarily through the PGE(2) receptor EP4 Cancer Immunol Immunother 60 11 2011 1577 1586
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.11 , pp. 1577-1586
    • Holt, D.1
  • 112
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • D. Wang, and R.N. Dubois Prostaglandins and cancer Gut 55 1 2006 115 122
    • (2006) Gut , vol.55 , Issue.1 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 113
    • 54749107201 scopus 로고    scopus 로고
    • Prevention of both direct and cross-priming of antitumor CD8+ T-cell responses following overproduction of prostaglandin E2 by tumor cells in vivo
    • M. Ahmadi, D.C. Emery, and D.J. Morgan Prevention of both direct and cross-priming of antitumor CD8+ T-cell responses following overproduction of prostaglandin E2 by tumor cells in vivo Cancer Res 68 18 2008 7520 7529
    • (2008) Cancer Res , vol.68 , Issue.18 , pp. 7520-7529
    • Ahmadi, M.1    Emery, D.C.2    Morgan, D.J.3
  • 114
    • 0037103366 scopus 로고    scopus 로고
    • Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells
    • E. Scandella Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells Blood 100 4 2002 1354 1361
    • (2002) Blood , vol.100 , Issue.4 , pp. 1354-1361
    • Scandella, E.1
  • 115
    • 0030606299 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
    • M. Oshima Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2) Cell 87 5 1996 803 809
    • (1996) Cell , vol.87 , Issue.5 , pp. 803-809
    • Oshima, M.1
  • 116
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • M. Tsujii Cyclooxygenase regulates angiogenesis induced by colon cancer cells Cell 93 1998 705 716
    • (1998) Cell , vol.93 , pp. 705-716
    • Tsujii, M.1
  • 117
    • 0037081194 scopus 로고    scopus 로고
    • Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps
    • H. Seno Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps Cancer Res 62 2 2002 506 511
    • (2002) Cancer Res , vol.62 , Issue.2 , pp. 506-511
    • Seno, H.1
  • 118
    • 33750855287 scopus 로고    scopus 로고
    • EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival
    • M. Kamiyama EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival Oncogene 25 53 2006 7019 7028
    • (2006) Oncogene , vol.25 , Issue.53 , pp. 7019-7028
    • Kamiyama, M.1
  • 119
    • 0035985272 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2), aromatase and breast cancer: A possible role for COX-2 inhibitors in breast cancer chemoprevention
    • G. Davies Cyclooxygenase-2 (COX-2), aromatase and breast cancer: a possible role for COX-2 inhibitors in breast cancer chemoprevention Ann Oncol 13 5 2002 669 678
    • (2002) Ann Oncol , vol.13 , Issue.5 , pp. 669-678
    • Davies, G.1
  • 120
    • 0036219594 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in endometrial cancer: Correlation with microvessel count and expression of vascular endothelial growth factor and thymidine phosphorylase
    • R. Fujiwaki Cyclooxygenase-2 expression in endometrial cancer: correlation with microvessel count and expression of vascular endothelial growth factor and thymidine phosphorylase Hum Pathol 33 2 2002 213 219
    • (2002) Hum Pathol , vol.33 , Issue.2 , pp. 213-219
    • Fujiwaki, R.1
  • 121
    • 0037599444 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression correlates with vascular endothelial growth factor expression and tumor angiogenesis in gastric cancer
    • Y.E. Joo Cyclooxygenase-2 overexpression correlates with vascular endothelial growth factor expression and tumor angiogenesis in gastric cancer J Clin Gastroenterol 37 1 2003 28 33
    • (2003) J Clin Gastroenterol , vol.37 , Issue.1 , pp. 28-33
    • Joo, Y.E.1
  • 122
    • 33644530425 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is associated with VEGF-C and lymph node metastases in gastric cancer patients
    • J. Zhang Cyclooxygenase-2 expression is associated with VEGF-C and lymph node metastases in gastric cancer patients Biomed Pharmacother 59 Suppl. 2 2005 S285 S288
    • (2005) Biomed Pharmacother , vol.59 , Issue.SUPPL. 2
    • Zhang, J.1
  • 123
    • 33646163924 scopus 로고    scopus 로고
    • COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer
    • A.V. Timoshenko COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer Br J Cancer 94 8 2006 1154 1163
    • (2006) Br J Cancer , vol.94 , Issue.8 , pp. 1154-1163
    • Timoshenko, A.V.1
  • 124
    • 33644971770 scopus 로고    scopus 로고
    • Coexpression of VEGF-C and Cox-2 in human colorectal cancer and its association with lymph node metastasis
    • L.T. Soumaoro Coexpression of VEGF-C and Cox-2 in human colorectal cancer and its association with lymph node metastasis Dis Colon Rectum 49 3 2006 392 398
    • (2006) Dis Colon Rectum , vol.49 , Issue.3 , pp. 392-398
    • Soumaoro, L.T.1
  • 125
    • 1642475162 scopus 로고    scopus 로고
    • Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: A novel mechanism of lymphangiogenesis in lung adenocarcinoma
    • J.L. Su Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinoma Cancer Res 64 2 2004 554 564
    • (2004) Cancer Res , vol.64 , Issue.2 , pp. 554-564
    • Su, J.L.1
  • 126
    • 35948974298 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis
    • C. Iwata Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis Cancer Res 67 21 2007 10181 10189
    • (2007) Cancer Res , vol.67 , Issue.21 , pp. 10181-10189
    • Iwata, C.1
  • 127
    • 79955583515 scopus 로고    scopus 로고
    • Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation
    • K. Hosono Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation Arterioscler Thromb Vasc Biol 31 5 2011 1049 1058
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , Issue.5 , pp. 1049-1058
    • Hosono, K.1
  • 128
    • 65949114869 scopus 로고    scopus 로고
    • Catecholamines regulate tumor angiogenesis
    • D. Chakroborty Catecholamines regulate tumor angiogenesis Cancer Res 69 9 2009 3727 3730
    • (2009) Cancer Res , vol.69 , Issue.9 , pp. 3727-3730
    • Chakroborty, D.1
  • 129
    • 79952587441 scopus 로고    scopus 로고
    • Transcript origin analysis identifies antigen-presenting cells as primary targets of socially regulated gene expression in leukocytes
    • S.W. Cole Transcript origin analysis identifies antigen-presenting cells as primary targets of socially regulated gene expression in leukocytes Proc Natl Acad Sci U S A 108 7 2011 3080 3085
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.7 , pp. 3080-3085
    • Cole, S.W.1
  • 130
    • 58149269564 scopus 로고    scopus 로고
    • Biobehavioral influences on matrix metalloproteinase expression in ovarian carcinoma
    • S.K. Lutgendorf Biobehavioral influences on matrix metalloproteinase expression in ovarian carcinoma Clin Cancer Res 14 21 2008 6839 6846
    • (2008) Clin Cancer Res , vol.14 , Issue.21 , pp. 6839-6846
    • Lutgendorf, S.K.1
  • 131
    • 84877049285 scopus 로고    scopus 로고
    • Biologic effects of dopamine on tumor vasculature in ovarian carcinoma
    • M. Moreno-Smith Biologic effects of dopamine on tumor vasculature in ovarian carcinoma Neoplasia 15 5 2013 502 510
    • (2013) Neoplasia , vol.15 , Issue.5 , pp. 502-510
    • Moreno-Smith, M.1
  • 132
    • 0019278591 scopus 로고
    • Lymphatic motility
    • I.C. Roddie Lymphatic motility Lymphology 13 4 1980 166 172
    • (1980) Lymphology , vol.13 , Issue.4 , pp. 166-172
    • Roddie, I.C.1
  • 133
    • 84940134896 scopus 로고
    • Lymphatic innervation
    • N.G. McHale Lymphatic innervation Blood Vessels 27 2-5 1990 127 136
    • (1990) Blood Vessels , vol.27 , Issue.25 , pp. 127-136
    • McHale, N.G.1
  • 134
    • 82255180781 scopus 로고    scopus 로고
    • Beta-adrenergic receptors (beta-AR) regulate VEGF and IL-6 production by divergent pathways in high beta-AR-expressing breast cancer cell lines
    • K.S. Madden, M.J. Szpunar, and E.B. Brown Beta-adrenergic receptors (beta-AR) regulate VEGF and IL-6 production by divergent pathways in high beta-AR-expressing breast cancer cell lines Breast Cancer Res Treat 130 3 2011 747 758
    • (2011) Breast Cancer Res Treat , vol.130 , Issue.3 , pp. 747-758
    • Madden, K.S.1    Szpunar, M.J.2    Brown, E.B.3
  • 135
    • 35948981785 scopus 로고    scopus 로고
    • Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer
    • C.N. Landen Jr. Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer Cancer Res 67 21 2007 10389 10396
    • (2007) Cancer Res , vol.67 , Issue.21 , pp. 10389-10396
    • Landen, Jr.C.N.1
  • 136
    • 77957727097 scopus 로고    scopus 로고
    • Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer
    • M. Shi Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer Mol Cancer 9 2010 269
    • (2010) Mol Cancer , vol.9 , pp. 269
    • Shi, M.1
  • 137
    • 33751261895 scopus 로고    scopus 로고
    • Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells
    • E.V. Yang Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells Cancer Res 66 21 2006 10357 10364
    • (2006) Cancer Res , vol.66 , Issue.21 , pp. 10357-10364
    • Yang, E.V.1
  • 138
    • 77951863320 scopus 로고    scopus 로고
    • Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis
    • A.K. Sood Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis J Clin Invest 120 5 2010 1515 1523
    • (2010) J Clin Invest , vol.120 , Issue.5 , pp. 1515-1523
    • Sood, A.K.1
  • 139
    • 34347206025 scopus 로고    scopus 로고
    • Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation
    • K.S. Sastry Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation J Biol Chem 282 19 2007 14094 14100
    • (2007) J Biol Chem , vol.282 , Issue.19 , pp. 14094-14100
    • Sastry, K.S.1
  • 140
    • 84866952117 scopus 로고    scopus 로고
    • Towards the biomarker-guided rational use of anti-angiogenic agents in the treatment of metastatic colorectal cancer
    • M.M. Halford, N.C. Tebbutt, and J. Desai Towards the biomarker-guided rational use of anti-angiogenic agents in the treatment of metastatic colorectal cancer Colorectal Cancer 1 2 2012 149 161
    • (2012) Colorectal Cancer , vol.1 , Issue.2 , pp. 149-161
    • Halford, M.M.1    Tebbutt, N.C.2    Desai, J.3
  • 141
    • 34047175559 scopus 로고    scopus 로고
    • Targeting VEGF-A to treat cancer and age-related macular degeneration
    • N. Ferrara Targeting VEGF-A to treat cancer and age-related macular degeneration Annu Rev Med 58 2007 491 504
    • (2007) Annu Rev Med , vol.58 , pp. 491-504
    • Ferrara, N.1
  • 142
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • R.K. Jain Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy Science 307 5706 2005 58 62
    • (2005) Science , vol.307 , Issue.5706 , pp. 58-62
    • Jain, R.K.1
  • 144
    • 84883745262 scopus 로고    scopus 로고
    • An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
    • A.S. Chung, X. Wu, and G. Zhuang An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy Nature Med 19 9 2013 1114 1123
    • (2013) Nature Med , vol.19 , Issue.9 , pp. 1114-1123
    • Chung, A.S.1    Wu, X.2    Zhuang, G.3
  • 145
    • 79952456041 scopus 로고    scopus 로고
    • The VD1 neutralizing antibody to vascular endothelial growth factor-D: Binding epitope and relationship to receptor binding
    • N. Davydova The VD1 neutralizing antibody to vascular endothelial growth factor-D: binding epitope and relationship to receptor binding J Mol Biol 407 4 2011 581 593
    • (2011) J Mol Biol , vol.407 , Issue.4 , pp. 581-593
    • Davydova, N.1
  • 146
    • 3042587472 scopus 로고    scopus 로고
    • Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C
    • K. Persaud Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C J Cell Science 117 Pt 13 2004 2745 2756
    • (2004) J Cell Science , vol.117 , Issue.PART 13 , pp. 2745-2756
    • Persaud, K.1
  • 147
    • 41249088330 scopus 로고    scopus 로고
    • Blocking neuropilin-2 function inhibits tumor cell metastasis
    • M. Caunt Blocking neuropilin-2 function inhibits tumor cell metastasis Cancer Cell 13 4 2008 331 342
    • (2008) Cancer Cell , vol.13 , Issue.4 , pp. 331-342
    • Caunt, M.1
  • 148
    • 0037024472 scopus 로고    scopus 로고
    • Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
    • Y. He Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling J Natl Cancer Inst 94 11 2002 819 825
    • (2002) J Natl Cancer Inst , vol.94 , Issue.11 , pp. 819-825
    • He, Y.1
  • 149
    • 84859089030 scopus 로고    scopus 로고
    • Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis
    • T. Holopainen Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis J Natl Cancer Inst 104 6 2012 461 475
    • (2012) J Natl Cancer Inst , vol.104 , Issue.6 , pp. 461-475
    • Holopainen, T.1
  • 150
    • 84868237540 scopus 로고    scopus 로고
    • Experience with sorafenib in the treatment of advanced renal cell carcinoma
    • G. Procopio Experience with sorafenib in the treatment of advanced renal cell carcinoma Ther Adv Urol 4 6 2012 303 313
    • (2012) Ther Adv Urol , vol.4 , Issue.6 , pp. 303-313
    • Procopio, G.1
  • 151
    • 84876044176 scopus 로고    scopus 로고
    • Pazopanib, a new therapy for metastatic soft tissue sarcoma
    • J. Verweij, and S. Sleijfer Pazopanib, a new therapy for metastatic soft tissue sarcoma Expert Opin Pharmacother 14 7 2013 929 935
    • (2013) Expert Opin Pharmacother , vol.14 , Issue.7 , pp. 929-935
    • Verweij, J.1    Sleijfer, S.2
  • 152
    • 84875157974 scopus 로고    scopus 로고
    • Sunitinib malate for the treatment of pancreas malignancies - Where does it fit?
    • P. Mankal, and E. O'Reilly Sunitinib malate for the treatment of pancreas malignancies - where does it fit? Expert Opin Pharmacother 14 6 2013 783 792
    • (2013) Expert Opin Pharmacother , vol.14 , Issue.6 , pp. 783-792
    • Mankal, P.1    O'Reilly, E.2
  • 153
    • 84873928134 scopus 로고    scopus 로고
    • Axitinib for the treatment of patients with advanced metastatic renal cell carcinoma (mRCC) after failure of prior systemic treatment
    • V. Grunwald, and A.S. Merseburger Axitinib for the treatment of patients with advanced metastatic renal cell carcinoma (mRCC) after failure of prior systemic treatment Onco Targets Ther 5 2012 111 117
    • (2012) Onco Targets Ther , vol.5 , pp. 111-117
    • Grunwald, V.1    Merseburger, A.S.2
  • 154
    • 84874725276 scopus 로고    scopus 로고
    • The development of regorafenib and its current and potential future role in cancer therapy
    • S.L. Davis The development of regorafenib and its current and potential future role in cancer therapy Drugs Today (Barc) 49 2 2013 105 115
    • (2013) Drugs Today (Barc) , vol.49 , Issue.2 , pp. 105-115
    • Davis, S.L.1
  • 155
    • 33644837942 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs for cancer prevention: Promise, perils and pharmacogenetics
    • C.M. Ulrich, J. Bigler, and J.D. Potter Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics Nat Rev Cancer 6 2 2006 130 140
    • (2006) Nat Rev Cancer , vol.6 , Issue.2 , pp. 130-140
    • Ulrich, C.M.1    Bigler, J.2    Potter, J.D.3
  • 156
    • 0028921225 scopus 로고
    • Nonsteroidal anti-inflammatory drug use and sporadic colorectal adenomas
    • R.N. DuBois Nonsteroidal anti-inflammatory drug use and sporadic colorectal adenomas Gastroenterology 108 4 1995 1310 1314
    • (1995) Gastroenterology , vol.108 , Issue.4 , pp. 1310-1314
    • Dubois, R.N.1
  • 157
    • 0037138743 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues
    • M.J. Thun, S.J. Henley, and C. Patrono Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues J Natl Cancer Inst 94 4 2002 252 266
    • (2002) J Natl Cancer Inst , vol.94 , Issue.4 , pp. 252-266
    • Thun, M.J.1    Henley, S.J.2    Patrono, C.3
  • 158
    • 84863412124 scopus 로고    scopus 로고
    • Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: Analysis of the time course of risks and benefits in 51 randomised controlled trials
    • P.M. Rothwell, J.F. Price, and F.G. Fowkes Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials Lancet 379 9826 2012 Apr 28 1602 1612
    • (2012) Lancet , vol.379 , Issue.9826 , pp. 1602-1612
    • Rothwell, P.M.1    Price, J.F.2    Fowkes, F.G.3
  • 159
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: A study of incident cancers during randomised controlled trials
    • P.M. Rothwell Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials Lancet 379 2012 1591 1601
    • (2012) Lancet , vol.379 , pp. 1591-1601
    • Rothwell, P.M.1
  • 160
    • 0023687241 scopus 로고
    • Colorectal cancer risk, chronic illnesses, operations, and medications: Case control results from the Melbourne Colorectal Cancer Study
    • G.A. Kune, S. Kune, and L.F. Watson Colorectal cancer risk, chronic illnesses, operations, and medications: case control results from the Melbourne Colorectal Cancer Study Cancer Res 48 15 1988 4399 4404
    • (1988) Cancer Res , vol.48 , Issue.15 , pp. 4399-4404
    • Kune, G.A.1    Kune, S.2    Watson, L.F.3
  • 161
    • 84860386459 scopus 로고    scopus 로고
    • The role of aspirin in cancer prevention
    • M.J. Thun, E.J. Jacobs, and C. Patrono The role of aspirin in cancer prevention Nat Rev Clin Oncol 9 5 2012 Apr 3 259 267
    • (2012) Nat Rev Clin Oncol , vol.9 , Issue.5 , pp. 259-267
    • Thun, M.J.1    Jacobs, E.J.2    Patrono, C.3
  • 162
    • 78650825618 scopus 로고    scopus 로고
    • Effect of daily aspirin on long-term risk of death due to cancer: Analysis of individual patient data from randomised trials
    • P.M. Rothwell Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials Lancet 377 9759 2011 31 41
    • (2011) Lancet , vol.377 , Issue.9759 , pp. 31-41
    • Rothwell, P.M.1
  • 163
    • 0036801502 scopus 로고    scopus 로고
    • Aspirin use in relation to risk of prostate cancer
    • M.F. Leitzmann Aspirin use in relation to risk of prostate cancer Cancer Epidemiol Biomarkers Prev 11 10 Pt 1 2002 1108 1111
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , Issue.10 PART 1 , pp. 1108-1111
    • Leitzmann, M.F.1
  • 164
    • 77956969905 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug (NSAID) use and breast cancer risk in the Western New York Exposures and Breast Cancer (WEB) Study
    • T.M. Brasky Non-steroidal anti-inflammatory drug (NSAID) use and breast cancer risk in the Western New York Exposures and Breast Cancer (WEB) Study Cancer Causes Control 21 9 2010 1503 1512
    • (2010) Cancer Causes Control , vol.21 , Issue.9 , pp. 1503-1512
    • Brasky, T.M.1
  • 165
    • 77950509620 scopus 로고    scopus 로고
    • A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases
    • H.A. Hirsch A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases Cancer Cell 17 4 2010 348 361
    • (2010) Cancer Cell , vol.17 , Issue.4 , pp. 348-361
    • Hirsch, H.A.1
  • 166
    • 77951921896 scopus 로고    scopus 로고
    • Aspirin intake and survival after breast cancer
    • M.D. Holmes Aspirin intake and survival after breast cancer J Clin Oncol 28 9 2010 1467 1472
    • (2010) J Clin Oncol , vol.28 , Issue.9 , pp. 1467-1472
    • Holmes, M.D.1
  • 167
    • 20444453338 scopus 로고    scopus 로고
    • Coexpression of cyclooxygenases (COX-1, COX-2) and vascular endothelial growth factors (VEGF-A, VEGF-C) in esophageal adenocarcinoma
    • B.H. von Rahden Coexpression of cyclooxygenases (COX-1, COX-2) and vascular endothelial growth factors (VEGF-A, VEGF-C) in esophageal adenocarcinoma Cancer Res 65 12 2005 5038 5044
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 5038-5044
    • Von Rahden, B.H.1
  • 168
    • 64849084071 scopus 로고    scopus 로고
    • The effect of cyclooxygenase-2 on lymphangiogenesis in breast cancer
    • G.L. Guo The effect of cyclooxygenase-2 on lymphangiogenesis in breast cancer Zhonghua Wai Ke Za Zhi 46 2 2008 132 135
    • (2008) Zhonghua Wai Ke Za Zhi , vol.46 , Issue.2 , pp. 132-135
    • Guo, G.L.1
  • 169
    • 35649012558 scopus 로고    scopus 로고
    • Spontaneous regression of recurrent and metastatic Merkel cell carcinoma
    • H. Kubo Spontaneous regression of recurrent and metastatic Merkel cell carcinoma J Dermatol 34 11 2007 773 777
    • (2007) J Dermatol , vol.34 , Issue.11 , pp. 773-777
    • Kubo, H.1
  • 170
    • 70449633544 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via VEGF-C
    • H. Liu Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via VEGF-C Anat Rec (Hoboken) 292 10 2009 1577 1583
    • (2009) Anat Rec (Hoboken) , vol.292 , Issue.10 , pp. 1577-1583
    • Liu, H.1
  • 171
    • 0000650598 scopus 로고
    • A new adrenergic betareceptor antagonist
    • J.W. Black A new adrenergic betareceptor antagonist Lancet 1 7342 1964 1080 1081
    • (1964) Lancet , vol.1 , Issue.7342 , pp. 1080-1081
    • Black, J.W.1
  • 172
    • 65249085625 scopus 로고    scopus 로고
    • Surgical stress promotes tumor growth in ovarian carcinoma
    • J.W. Lee Surgical stress promotes tumor growth in ovarian carcinoma Clin Cancer Res 15 8 2009 2695 2702
    • (2009) Clin Cancer Res , vol.15 , Issue.8 , pp. 2695-2702
    • Lee, J.W.1
  • 173
    • 78149414483 scopus 로고    scopus 로고
    • Effect of beta blocker combined with COX-2 inhibitor on colonic anastomosis in rats
    • B. Benjamin Effect of beta blocker combined with COX-2 inhibitor on colonic anastomosis in rats Int J Colorectal Dis 25 12 2010 1459 1464
    • (2010) Int J Colorectal Dis , vol.25 , Issue.12 , pp. 1459-1464
    • Benjamin, B.1
  • 174
    • 79960141295 scopus 로고    scopus 로고
    • Beta-blocker use is associated with improved relapse-free survival in patients with triple-negative breast cancer
    • A. Melhem-Bertrandt Beta-blocker use is associated with improved relapse-free survival in patients with triple-negative breast cancer J Clin Oncol 29 19 2011 2645 2652
    • (2011) J Clin Oncol , vol.29 , Issue.19 , pp. 2645-2652
    • Melhem-Bertrandt, A.1
  • 175
    • 84898702870 scopus 로고    scopus 로고
    • Therapeutic effect of beta-blockers in triple-negative breast cancer postmenopausal women
    • E. Botteri Therapeutic effect of beta-blockers in triple-negative breast cancer postmenopausal women Breast Cancer Res Treat 140 3 2013 567 575
    • (2013) Breast Cancer Res Treat , vol.140 , Issue.3 , pp. 567-575
    • Botteri, E.1
  • 176
    • 80052608472 scopus 로고    scopus 로고
    • Examining the influence of beta blockers and ACE inhibitors on the risk for breast cancer recurrence: Results from the LACE cohort
    • P.A. Ganz Examining the influence of beta blockers and ACE inhibitors on the risk for breast cancer recurrence: results from the LACE cohort Breast Cancer Res Treat 129 2 2011 549 556
    • (2011) Breast Cancer Res Treat , vol.129 , Issue.2 , pp. 549-556
    • Ganz, P.A.1
  • 177
    • 84882947561 scopus 로고    scopus 로고
    • Use of beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and risk of breast cancer recurrence: A Danish nationwide prospective cohort study
    • G.V. Sorensen Use of beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and risk of breast cancer recurrence: a Danish nationwide prospective cohort study J Clin Oncol 31 18 2013 2265 2272
    • (2013) J Clin Oncol , vol.31 , Issue.18 , pp. 2265-2272
    • Sorensen, G.V.1
  • 178
    • 79953658412 scopus 로고    scopus 로고
    • Beta-blocker drug therapy reduces secondary cancer formation in breast cancer and improves cancer specific survival
    • D.G. Powe Beta-blocker drug therapy reduces secondary cancer formation in breast cancer and improves cancer specific survival Oncotarget 1 7 2010 628 638
    • (2010) Oncotarget , vol.1 , Issue.7 , pp. 628-638
    • Powe, D.G.1
  • 179
    • 84883009175 scopus 로고    scopus 로고
    • Use of ACE inhibitors and angiotensin receptor blockers and primary breast cancer outcomes
    • Y.K. Chae Use of ACE inhibitors and angiotensin receptor blockers and primary breast cancer outcomes J Cancer 4 7 2013 549 556
    • (2013) J Cancer , vol.4 , Issue.7 , pp. 549-556
    • Chae, Y.K.1
  • 180
    • 80054848246 scopus 로고    scopus 로고
    • Reduced risk of breast cancer recurrence in patients using ACE inhibitors, ARBs, and/or statins
    • Y.K. Chae Reduced risk of breast cancer recurrence in patients using ACE inhibitors, ARBs, and/or statins Cancer Invest 29 9 2011 585 593
    • (2011) Cancer Invest , vol.29 , Issue.9 , pp. 585-593
    • Chae, Y.K.1
  • 181
    • 84895062464 scopus 로고    scopus 로고
    • Association between use of beta-blockers and prostate cancer-specific survival: A cohort study of 3561 prostate cancer patients with high-risk or metastatic disease
    • S0302-2838(13) 00010-9
    • H.H. Grytli Association between use of beta-blockers and prostate cancer-specific survival: a cohort study of 3561 prostate cancer patients with high-risk or metastatic disease Eur Urol 2013 S0302-2838(13) 00010-9
    • (2013) Eur Urol
    • Grytli, H.H.1
  • 182
    • 84872800402 scopus 로고    scopus 로고
    • Use of beta-blockers is associated with prostate cancer-specific survival in prostate cancer patients on androgen deprivation therapy
    • H.H. Grytli Use of beta-blockers is associated with prostate cancer-specific survival in prostate cancer patients on androgen deprivation therapy Prostate 73 3 2013 250 260
    • (2013) Prostate , vol.73 , Issue.3 , pp. 250-260
    • Grytli, H.H.1
  • 183
    • 84875699061 scopus 로고    scopus 로고
    • Strategies for improving the clinical benefit of antiangiogenic drug based therapies for breast cancer
    • R.S. Kerbel Strategies for improving the clinical benefit of antiangiogenic drug based therapies for breast cancer J Mammary Gland Biol Neoplasia 17 3-4 2012 229 239
    • (2012) J Mammary Gland Biol Neoplasia , vol.17 , Issue.34 , pp. 229-239
    • Kerbel, R.S.1
  • 184
    • 80955180176 scopus 로고    scopus 로고
    • Beta2-adrenoceptor blocker synergizes with gemcitabine to inhibit the proliferation of pancreatic cancer cells via apoptosis induction
    • T. Shan Beta2-adrenoceptor blocker synergizes with gemcitabine to inhibit the proliferation of pancreatic cancer cells via apoptosis induction Eur J Pharmacol 665 1-3 2011 1 7
    • (2011) Eur J Pharmacol , vol.665 , Issue.13 , pp. 1-7
    • Shan, T.1
  • 185
    • 77949900433 scopus 로고    scopus 로고
    • Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: Combating tumor evasion of antiangiogenic therapy
    • S.J. Priceman Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy Blood 115 7 2010 1461 1471
    • (2010) Blood , vol.115 , Issue.7 , pp. 1461-1471
    • Priceman, S.J.1


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