-
1
-
-
34248573977
-
Census of Vertebrate Wnt Genes: Isolation and Developmental Expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16
-
Garriock, R. J.; Warkman, A. S.; Meadows, S. M.; D'Agostino, S.; Krieg, P. A. Census of Vertebrate Wnt Genes: Isolation and Developmental Expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16. Dev. Dyn. 2007, 236, 1249-1258.
-
(2007)
Dev. Dyn
, vol.236
, pp. 1249-1258
-
-
Garriock, R.J.1
Warkman, A.S.2
Meadows, S.M.3
D'Agostino, S.4
Krieg, P.A.5
-
2
-
-
0037737726
-
Wnt Proteins Are Lipid-Modified and Can Act as Stem Cell Growth Factors
-
Willert, K.; Brown, J. D.; Danenberg, E.; Duncan, A. W.; Weissman, I. L.; Reya, T.; Yates, J. R., 3rd; Nusse, R. Wnt Proteins Are Lipid-Modified and Can Act as Stem Cell Growth Factors. Nature 2003, 423, 448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Yates 3rd, J.R.7
Nusse, R.8
-
3
-
-
0029844909
-
Glycosaminoglycans Can Modulate Extracellular Localization of the Wingless Protein and Promote Signal Transduction
-
Reichsman, F.; Smith, L.; Cumberledge, S. Glycosaminoglycans Can Modulate Extracellular Localization of the Wingless Protein and Promote Signal Transduction. J. Cell Biol. 1996, 135, 819-827.
-
(1996)
J. Cell Biol
, vol.135
, pp. 819-827
-
-
Reichsman, F.1
Smith, L.2
Cumberledge, S.3
-
4
-
-
33644967242
-
Wnt Signaling: Complexity at the Surface
-
Cadigan, K. M.; Liu, Y. I. Wnt Signaling: Complexity at the Surface. J. Cell Sci. 2006, 119, 395-402.
-
(2006)
J. Cell Sci
, vol.119
, pp. 395-402
-
-
Cadigan, K.M.1
Liu, Y.I.2
-
5
-
-
0032492954
-
Downregulation of Beta-Catenin by Human Axin and Its Association with the APC Tumor Suppressor, Beta-Catenin and GSK3 Beta
-
Hart, M. J.; de los Santos, R.; Albert, I. N.; Rubinfeld, B.; Polakis, P. Downregulation of Beta-Catenin by Human Axin and Its Association with the APC Tumor Suppressor, Beta-Catenin and GSK3 Beta. Curr. Biol. 1998, 8, 573-581.
-
(1998)
Curr. Biol
, vol.8
, pp. 573-581
-
-
Hart, M.J.1
de los2
Santos, R.3
Albert, I.N.4
Rubinfeld, B.5
Polakis, P.6
-
6
-
-
0032079884
-
-
Kishida, S.; Yamamoto, H.; Ikeda, S.; Kishida, M.; Sakamoto, I.; Koyama, S.; Kikuchi, A. Axin, a Negative Regulator of the Wnt Signaling Pathway, Directly Interacts with Adenomatous Polyposis Coli and Regulates the Stabilization of Beta-Catenin. J. Biol. Chem. 1998, 273, 10823-10826.
-
Kishida, S.; Yamamoto, H.; Ikeda, S.; Kishida, M.; Sakamoto, I.; Koyama, S.; Kikuchi, A. Axin, a Negative Regulator of the Wnt Signaling Pathway, Directly Interacts with Adenomatous Polyposis Coli and Regulates the Stabilization of Beta-Catenin. J. Biol. Chem. 1998, 273, 10823-10826.
-
-
-
-
7
-
-
0036571011
-
Axin-Mediated CKI Phosphorylation of Beta-Catenin at Ser 45: A Molecular Switch for the Wnt Pathway
-
Amit, S.; Hatzubai, A.; Birman, Y.; Andersen, J. S.; Ben-Shushan, E.; Mann, M.; Ben-Neriah, Y.; Alkalay, I. Axin-Mediated CKI Phosphorylation of Beta-Catenin at Ser 45: A Molecular Switch for the Wnt Pathway. Genes Dev. 2002, 16, 1066-1076.
-
(2002)
Genes Dev
, vol.16
, pp. 1066-1076
-
-
Amit, S.1
Hatzubai, A.2
Birman, Y.3
Andersen, J.S.4
Ben-Shushan, E.5
Mann, M.6
Ben-Neriah, Y.7
Alkalay, I.8
-
8
-
-
0033522491
-
An F-Box Protein, FWD1, Mediates Ubiquitin-Dependent Proteolysis of Beta-Catenin
-
Kitagawa, M.; Hatakeyama, S.; Shirane, M.; Matsumoto, M.; Ishida, N.; Hattori, K.; Nakamichi, I.; Kikuchi, A.; Nakayama, K.; Nakayama, K. An F-Box Protein, FWD1, Mediates Ubiquitin-Dependent Proteolysis of Beta-Catenin. EMBO J. 1999, 18, 2401-2410.
-
(1999)
EMBO J
, vol.18
, pp. 2401-2410
-
-
Kitagawa, M.1
Hatakeyama, S.2
Shirane, M.3
Matsumoto, M.4
Ishida, N.5
Hattori, K.6
Nakamichi, I.7
Kikuchi, A.8
Nakayama, K.9
Nakayama, K.10
-
9
-
-
0033034120
-
Beta-Trcp Couples Beta-Catenin Phosphorylation-Degradation and Regulates Xenopus Axis Formation
-
Liu, C.; Kato, Y.; Zhang, Z.; Do, V. M.; Yankner, B. A.; He, X. Beta-Trcp Couples Beta-Catenin Phosphorylation-Degradation and Regulates Xenopus Axis Formation. Proc. Natl. Acad. Sci. USA 1999, 96, 6273-6278.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6273-6278
-
-
Liu, C.1
Kato, Y.2
Zhang, Z.3
Do, V.M.4
Yankner, B.A.5
He, X.6
-
10
-
-
0033597886
-
Characterization of Mouse Dishevelled (Dvl) Proteins in Wnt/Wingless Signaling Pathway
-
Lee, J. S.; Ishimoto, A.; Yanagawa, S. Characterization of Mouse Dishevelled (Dvl) Proteins in Wnt/Wingless Signaling Pathway. J. Biol. Chem. 1999, 274, 21464-21470.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 21464-21470
-
-
Lee, J.S.1
Ishimoto, A.2
Yanagawa, S.3
-
11
-
-
1642564513
-
A Mechanism for Wnt Coreceptor Activation
-
Tamai, K.; Zeng, X.; Liu, C.; Zhang, X.; Harada, Y.; Chang, Z.; He, X. A Mechanism for Wnt Coreceptor Activation. Mol. Cell 2004, 13, 149-156.
-
(2004)
Mol. Cell
, vol.13
, pp. 149-156
-
-
Tamai, K.1
Zeng, X.2
Liu, C.3
Zhang, X.4
Harada, Y.5
Chang, Z.6
He, X.7
-
12
-
-
24644499046
-
Wnt and Calcium Signaling: Beta-Catenin- Independent Pathways
-
Kohn, A. D.; Moon, R. T. Wnt and Calcium Signaling: Beta-Catenin- Independent Pathways. Cell Calcium 2005, 38, 439-446.
-
(2005)
Cell Calcium
, vol.38
, pp. 439-446
-
-
Kohn, A.D.1
Moon, R.T.2
-
13
-
-
0037439138
-
Coactivation of Rac and Rho by Wnt/Frizzled Signaling Is Required for Vertebrate Gastrulation
-
Habas, R.; Dawid, I. B.; He, X. Coactivation of Rac and Rho by Wnt/Frizzled Signaling Is Required for Vertebrate Gastrulation. Genes Dev. 2003, 17, 295-309.
-
(2003)
Genes Dev
, vol.17
, pp. 295-309
-
-
Habas, R.1
Dawid, I.B.2
He, X.3
-
14
-
-
33846396811
-
Frizzled/PCP Signalling: A Conserved Mechanism Regulating Cell Polarity and Directed Motility
-
Seifert, J. R.; Mlodzik, M. Frizzled/PCP Signalling: A Conserved Mechanism Regulating Cell Polarity and Directed Motility. Nat. Rev. Genet. 2007, 8, 126-138.
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 126-138
-
-
Seifert, J.R.1
Mlodzik, M.2
-
15
-
-
0034604096
-
Silberblick/Wnt11 Mediates Convergent Extension Movements During Zebrafish Gastrulation
-
Heisenberg, C. P.; Tada, M.; Rauch, G. J.; Saude, L.; Concha, M. L.; Geisler, R.; Stemple, D. L.; Smith, J. C.; Wilson, S. W. Silberblick/Wnt11 Mediates Convergent Extension Movements During Zebrafish Gastrulation. Nature 2000, 405, 76-81.
-
(2000)
Nature
, vol.405
, pp. 76-81
-
-
Heisenberg, C.P.1
Tada, M.2
Rauch, G.J.3
Saude, L.4
Concha, M.L.5
Geisler, R.6
Stemple, D.L.7
Smith, J.C.8
Wilson, S.W.9
-
16
-
-
0034130385
-
Xwnt11 Is a Target of Xenopus Brachyury: Regulation of Gastrulation Movements Via Dishevelled, but Not Through the Canonical Wnt Pathway
-
Tada, M.; Smith, J. C. Xwnt11 Is a Target of Xenopus Brachyury: Regulation of Gastrulation Movements Via Dishevelled, but Not Through the Canonical Wnt Pathway. Development 2000, 127, 2227-2238.
-
(2000)
Development
, vol.127
, pp. 2227-2238
-
-
Tada, M.1
Smith, J.C.2
-
17
-
-
0034604076
-
Dishevelled Controls Cell Polarity During Xenopus Gastrulation
-
Wallingford, J. B.; Rowning, B. A.; Vogeli, K. M.; Rothbacher, U.; Fraser, S. E.; Harland, R. M. Dishevelled Controls Cell Polarity During Xenopus Gastrulation. Nature 2000, 405, 81-85.
-
(2000)
Nature
, vol.405
, pp. 81-85
-
-
Wallingford, J.B.1
Rowning, B.A.2
Vogeli, K.M.3
Rothbacher, U.4
Fraser, S.E.5
Harland, R.M.6
-
18
-
-
12444329708
-
Wnt Signaling Mediates Reorientation of Outer Hair Cell Stereociliary Bundles in the Mammalian Cochlea
-
Dabdoub, A.; Donohue, M. J.; Brennan, A.; Wolf, V.; Montcouquiol, M.; Sassoon, D. A.; Hseih, J. C.; Rubin, J. S.; Salinas, P. C.; Kelley, M. W. Wnt Signaling Mediates Reorientation of Outer Hair Cell Stereociliary Bundles in the Mammalian Cochlea. Development 2003, 130, 2375-2384.
-
(2003)
Development
, vol.130
, pp. 2375-2384
-
-
Dabdoub, A.1
Donohue, M.J.2
Brennan, A.3
Wolf, V.4
Montcouquiol, M.5
Sassoon, D.A.6
Hseih, J.C.7
Rubin, J.S.8
Salinas, P.C.9
Kelley, M.W.10
-
19
-
-
0030933978
-
Frzb-1 Is a Secreted Antagonist of Wnt Signaling Expressed in the Spemann Organizer
-
Leyns, L.; Bouwmeester, T.; Kim, S. H.; Piccolo, S.; De Robertis, E. M. Frzb-1 Is a Secreted Antagonist of Wnt Signaling Expressed in the Spemann Organizer. Cell 1997, 88, 747-756.
-
(1997)
Cell
, vol.88
, pp. 747-756
-
-
Leyns, L.1
Bouwmeester, T.2
Kim, S.H.3
Piccolo, S.4
De Robertis, E.M.5
-
20
-
-
0030960454
-
-
Mayr, T.; Deutsch, U.; Kuhl, M.; Drexler, H. C.; Lottspeich, F.; Deutzmann, R.; Wedlich, D.; Risau, W. Fritz: A Secreted Frizzled-Related Protein That Inhibits Wnt Activity. Mech. Dev. 1997, 63, 109-125.
-
Mayr, T.; Deutsch, U.; Kuhl, M.; Drexler, H. C.; Lottspeich, F.; Deutzmann, R.; Wedlich, D.; Risau, W. Fritz: A Secreted Frizzled-Related Protein That Inhibits Wnt Activity. Mech. Dev. 1997, 63, 109-125.
-
-
-
-
21
-
-
0030905162
-
A Family of Secreted Proteins Contains Homology to the Cysteine-Rich Ligand-Binding Domain of Frizzled Receptors
-
Rattner, A.; Hsieh, J. C.; Smallwood, P. M.; Gilbert, D. J.; Copeland, N. G.; Jenkins, N. A.; Nathans, J. A Family of Secreted Proteins Contains Homology to the Cysteine-Rich Ligand-Binding Domain of Frizzled Receptors. Proc. Natl. Acad. Sci. USA 1997, 94, 2859-2863.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2859-2863
-
-
Rattner, A.1
Hsieh, J.C.2
Smallwood, P.M.3
Gilbert, D.J.4
Copeland, N.G.5
Jenkins, N.A.6
Nathans, J.7
-
22
-
-
0030892061
-
-
Wang, S.; Krinks, M.; Lin, K.; Luyten, F. P.; Moos, M., Jr. Frzb, a Secreted Protein Expressed in the Spemann Organizer, Binds and Inhibits Wnt-8. Cell 1997, 88, 757-766.
-
Wang, S.; Krinks, M.; Lin, K.; Luyten, F. P.; Moos, M., Jr. Frzb, a Secreted Protein Expressed in the Spemann Organizer, Binds and Inhibits Wnt-8. Cell 1997, 88, 757-766.
-
-
-
-
23
-
-
0033118492
-
A New Secreted Protein That Binds to Wnt Proteins and Inhibits Their Activities
-
Hsieh, J. C.; Kodjabachian, L.; Rebbert, M. L.; Rattner, A.; Smallwood, P. M.; Samos, C. H.; Nusse, R.; Dawid, I. B.; Nathans, J. A New Secreted Protein That Binds to Wnt Proteins and Inhibits Their Activities. Nature 1999, 398, 431-436.
-
(1999)
Nature
, vol.398
, pp. 431-436
-
-
Hsieh, J.C.1
Kodjabachian, L.2
Rebbert, M.L.3
Rattner, A.4
Smallwood, P.M.5
Samos, C.H.6
Nusse, R.7
Dawid, I.B.8
Nathans, J.9
-
24
-
-
0032556910
-
Dickkopf-1 Is a Member of a New Family of Secreted Proteins and Functions in Head Induction
-
Glinka, A.; Wu, W.; Delius, H.; Monaghan, A. P.; Blumenstock, C.; Niehrs, C. Dickkopf-1 Is a Member of a New Family of Secreted Proteins and Functions in Head Induction. Nature 1998, 391, 357-362.
-
(1998)
Nature
, vol.391
, pp. 357-362
-
-
Glinka, A.1
Wu, W.2
Delius, H.3
Monaghan, A.P.4
Blumenstock, C.5
Niehrs, C.6
-
25
-
-
0032850032
-
Functional and Structural Diversity of the Human Dickkopf Gene Family
-
Krupnik, V. E.; Sharp, J. D.; Jiang, C.; Robison, K.; Chickering, T. W.; Amaravadi, L.; Brown, D. E.; Guyot, D.; Mays, G.; Leiby, K.; Chang, B.; Duong, T.; Goodearl, A. D.; Gearing, D. P.; Sokol, S. Y.; McCarthy, S. A. Functional and Structural Diversity of the Human Dickkopf Gene Family. Gene 1999, 238, 301-313.
-
(1999)
Gene
, vol.238
, pp. 301-313
-
-
Krupnik, V.E.1
Sharp, J.D.2
Jiang, C.3
Robison, K.4
Chickering, T.W.5
Amaravadi, L.6
Brown, D.E.7
Guyot, D.8
Mays, G.9
Leiby, K.10
Chang, B.11
Duong, T.12
Goodearl, A.D.13
Gearing, D.P.14
Sokol, S.Y.15
McCarthy, S.A.16
-
26
-
-
0035902050
-
LDL-Receptor-Related Protein 6 Is a Receptor for Dickkopf Proteins
-
Mao, B.; Wu, W.; Li, Y.; Hoppe, D.; Stannek, P.; Glinka, A.; Niehrs, C. LDL-Receptor-Related Protein 6 Is a Receptor for Dickkopf Proteins. Nature 2001, 411, 321-325.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
Hoppe, D.4
Stannek, P.5
Glinka, A.6
Niehrs, C.7
-
27
-
-
9244240664
-
Dickkopf 3 Inhibits Invasion and Motility of Saos-2 Osteosarcoma Cells by Modulating the Wnt-Beta-Catenin Pathway
-
Hoang, B. H.; Kubo, T.; Healey, J. H.; Yang, R.; Nathan, S. S.; Kolb, E. A.; Mazza, B.; Meyers, P. A.; Gorlick, R. Dickkopf 3 Inhibits Invasion and Motility of Saos-2 Osteosarcoma Cells by Modulating the Wnt-Beta-Catenin Pathway. Cancer Res. 2004, 64, 2734-2739.
-
(2004)
Cancer Res
, vol.64
, pp. 2734-2739
-
-
Hoang, B.H.1
Kubo, T.2
Healey, J.H.3
Yang, R.4
Nathan, S.S.5
Kolb, E.A.6
Mazza, B.7
Meyers, P.A.8
Gorlick, R.9
-
28
-
-
0034933057
-
Novel Mechanism of Wnt Signalling Inhibition Mediated by Dickkopf-1 Interaction with LRP6/Arrow
-
Bafico, A.; Liu, G.; Yaniv, A.; Gazit, A.; Aaronson, S. A. Novel Mechanism of Wnt Signalling Inhibition Mediated by Dickkopf-1 Interaction with LRP6/Arrow. Nat. Cell Biol. 2001, 3, 683-686.
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 683-686
-
-
Bafico, A.1
Liu, G.2
Yaniv, A.3
Gazit, A.4
Aaronson, S.A.5
-
29
-
-
0035954281
-
Head Inducer Dickkopf-1 Is a Ligand for Wnt Coreceptor LRP6
-
Semenov, M. V.; Tamai, K.; Brott, B. K.; Kuhl, M.; Sokol, S.; He, X. Head Inducer Dickkopf-1 Is a Ligand for Wnt Coreceptor LRP6. Curr. Biol. 2001, 11, 951-961.
-
(2001)
Curr. Biol
, vol.11
, pp. 951-961
-
-
Semenov, M.V.1
Tamai, K.2
Brott, B.K.3
Kuhl, M.4
Sokol, S.5
He, X.6
-
30
-
-
0037030681
-
Kremen Proteins Are Dickkopf Receptors That Regulate Wnt/Beta-Catenin Signalling
-
Mao, B.; Wu, W.; Davidson, G.; Marhold, J.; Li, M.; Mechler, B. M.; Delius, H.; Hoppe, D.; Stannek, P.; Walter, C.; Glinka, A.; Niehrs, C. Kremen Proteins Are Dickkopf Receptors That Regulate Wnt/Beta-Catenin Signalling. Nature 2002, 417, 664-667.
-
(2002)
Nature
, vol.417
, pp. 664-667
-
-
Mao, B.1
Wu, W.2
Davidson, G.3
Marhold, J.4
Li, M.5
Mechler, B.M.6
Delius, H.7
Hoppe, D.8
Stannek, P.9
Walter, C.10
Glinka, A.11
Niehrs, C.12
-
31
-
-
0035138936
-
Revelations of the RYK Receptor
-
Halford, M. M.; Stacker, S. A. Revelations of the RYK Receptor. Bioessays 2001, 23, 34-45.
-
(2001)
Bioessays
, vol.23
, pp. 34-45
-
-
Halford, M.M.1
Stacker, S.A.2
-
32
-
-
0027104123
-
RYK, a Receptor Tyrosine Kinase-Related Molecule with Unusual Kinase Domain Motifs
-
Hovens, C. M.; Stacker, S. A.; Andres, A. C.; Harpur, A. G.; Ziemiecki, A.; Wilks, A. F. RYK, a Receptor Tyrosine Kinase-Related Molecule with Unusual Kinase Domain Motifs. Proc. Natl. Acad. Sci. USA 1992, 89, 11818-11822.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11818-11822
-
-
Hovens, C.M.1
Stacker, S.A.2
Andres, A.C.3
Harpur, A.G.4
Ziemiecki, A.5
Wilks, A.F.6
-
33
-
-
0029752981
-
H-RYK, an Unusual Receptor Kinase: Isolation and Analysis of Expression in Ovarian Cancer
-
Wang, X. C.; Katso, R.; Butler, R.; Hanby, A. M.; Poulsom, R.; Jones, T.; Sheer, D.; Ganesan, T. S. H-RYK, an Unusual Receptor Kinase: Isolation and Analysis of Expression in Ovarian Cancer. Mol. Med. 1996, 2, 189-203.
-
(1996)
Mol. Med
, vol.2
, pp. 189-203
-
-
Wang, X.C.1
Katso, R.2
Butler, R.3
Hanby, A.M.4
Poulsom, R.5
Jones, T.6
Sheer, D.7
Ganesan, T.S.8
-
34
-
-
0032812687
-
Functional Analysis of H-Ryk, an Atypical Member of the Receptor Tyrosine Kinase Family
-
Katso, R. M.; Russell, R. B.; Ganesan, T. S. Functional Analysis of H-Ryk, an Atypical Member of the Receptor Tyrosine Kinase Family. Mol. Cell. Biol. 1999, 19, 6427-6440.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 6427-6440
-
-
Katso, R.M.1
Russell, R.B.2
Ganesan, T.S.3
-
35
-
-
0032585638
-
-
Serfas, M. S.; Tyner, A. L. Ryk Is Expressed in a Differentiation- Specific Manner in Epithelial Tissues and Is Strongly Induced in Decidualizing Uterine Stroma. Oncogene 1998, 17, 3435-3444.
-
Serfas, M. S.; Tyner, A. L. Ryk Is Expressed in a Differentiation- Specific Manner in Epithelial Tissues and Is Strongly Induced in Decidualizing Uterine Stroma. Oncogene 1998, 17, 3435-3444.
-
-
-
-
36
-
-
4544329969
-
-
Inoue, T.; Oz, H. S.; Wiland, D.; Gharib, S.; Deshpande, R.; Hill, R. J.; Katz, W. S.; Sternberg, P. W. C. elegans LIN-18 Is a Ryk Ortholog and Functions in Parallel to LIN-17/Frizzled in Wnt Signaling. Cell 2004, 118, 795-806.
-
Inoue, T.; Oz, H. S.; Wiland, D.; Gharib, S.; Deshpande, R.; Hill, R. J.; Katz, W. S.; Sternberg, P. W. C. elegans LIN-18 Is a Ryk Ortholog and Functions in Parallel to LIN-17/Frizzled in Wnt Signaling. Cell 2004, 118, 795-806.
-
-
-
-
37
-
-
0028998860
-
Control of Neuronal Pathway Selection by a Drosophila Receptor Protein-Tyrosine Kinase Family Member
-
Callahan, C. A.; Muralidhar, M. G.; Lundgren, S. E.; Scully, A. L.; Thomas, J. B. Control of Neuronal Pathway Selection by a Drosophila Receptor Protein-Tyrosine Kinase Family Member. Nature 1995, 376, 171-174.
-
(1995)
Nature
, vol.376
, pp. 171-174
-
-
Callahan, C.A.1
Muralidhar, M.G.2
Lundgren, S.E.3
Scully, A.L.4
Thomas, J.B.5
-
38
-
-
0031649606
-
Embryonic Expression and Activity of Doughnut, a Second RYK Homolog in Drosophila
-
Oates, A. C.; Bonkovsky, J. L.; Irvine, D. V.; Kelly, L. E.; Thomas, J. B.; Wilks, A. F. Embryonic Expression and Activity of Doughnut, a Second RYK Homolog in Drosophila. Mech. Dev. 1998, 78, 165-169.
-
(1998)
Mech. Dev
, vol.78
, pp. 165-169
-
-
Oates, A.C.1
Bonkovsky, J.L.2
Irvine, D.V.3
Kelly, L.E.4
Thomas, J.B.5
Wilks, A.F.6
-
39
-
-
0031704334
-
The Receptor Tyrosine Kinase Gene Linotte Is Required for Neuronal Pathway Selection in the Drosophila Mushroom Bodies
-
Moreau-Fauvarque, C.; Taillebourg, E.; Boissoneau, E.; Mesnard, J.; Dura, J. M. The Receptor Tyrosine Kinase Gene Linotte Is Required for Neuronal Pathway Selection in the Drosophila Mushroom Bodies. Mech. Dev. 1998, 78, 47-61.
-
(1998)
Mech. Dev
, vol.78
, pp. 47-61
-
-
Moreau-Fauvarque, C.1
Taillebourg, E.2
Boissoneau, E.3
Mesnard, J.4
Dura, J.M.5
-
40
-
-
0034426014
-
RYK-Deficient Mice Exhibit Craniofacial Defects Associated with Perturbed Eph Receptor Crosstalk
-
Halford, M. M.; Armes, J.; Buchert, M.; Meskenaite, V.; Grail, D.; Hibbs, M. L.; Wilks, A. F.; Farlie, P. G.; Newgreen, D. F.; Hovens, C. M.; Stacker, S. A. RYK-Deficient Mice Exhibit Craniofacial Defects Associated with Perturbed Eph Receptor Crosstalk. Nat. Genet. 2000, 25, 414-418.
-
(2000)
Nat. Genet
, vol.25
, pp. 414-418
-
-
Halford, M.M.1
Armes, J.2
Buchert, M.3
Meskenaite, V.4
Grail, D.5
Hibbs, M.L.6
Wilks, A.F.7
Farlie, P.G.8
Newgreen, D.F.9
Hovens, C.M.10
Stacker, S.A.11
-
41
-
-
33744976112
-
The Wnt Receptor Ryk Is Required for Wnt5a-Mediated Axon Guidance on the Contralateral Side of the Corpus Callosum
-
Keeble, T. R.; Halford, M. M.; Seaman, C.; Kee, N.; Macheda, M.; Anderson, R. B.; Stacker, S. A.; Cooper, H. M. The Wnt Receptor Ryk Is Required for Wnt5a-Mediated Axon Guidance on the Contralateral Side of the Corpus Callosum. J. Neurosci. 2006, 26, 5840-5848.
-
(2006)
J. Neurosci
, vol.26
, pp. 5840-5848
-
-
Keeble, T.R.1
Halford, M.M.2
Seaman, C.3
Kee, N.4
Macheda, M.5
Anderson, R.B.6
Stacker, S.A.7
Cooper, H.M.8
-
42
-
-
0029858435
-
Sek4 and Nuk Receptors Cooperate in Guidance of Commissural Axons and in Palate Formation
-
Orioli, D.; Henkemeyer, M.; Lemke, G.; Klein, R.; Pawson, T. Sek4 and Nuk Receptors Cooperate in Guidance of Commissural Axons and in Palate Formation. EMBO J. 1996, 15, 6035-6049.
-
(1996)
EMBO J
, vol.15
, pp. 6035-6049
-
-
Orioli, D.1
Henkemeyer, M.2
Lemke, G.3
Klein, R.4
Pawson, T.5
-
43
-
-
13144256698
-
PDZ-Domain-Mediated Interaction of the Eph-Related Receptor Tyrosine Kinase EphB3 and the Ras-Binding Protein AF6 Depends on the Kinase Activity of the Receptor
-
Hock, B.; Bohme, B.; Karn, T.; Yamamoto, T.; Kaibuchi, K.; Holtrich, U.; Holland, S.; Pawson, T.; Rubsamen-Waigmann, H.; Strebhardt, K. PDZ-Domain-Mediated Interaction of the Eph-Related Receptor Tyrosine Kinase EphB3 and the Ras-Binding Protein AF6 Depends on the Kinase Activity of the Receptor. Proc. Natl. Acad. Sci. USA 1998, 95, 9779-9784.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9779-9784
-
-
Hock, B.1
Bohme, B.2
Karn, T.3
Yamamoto, T.4
Kaibuchi, K.5
Holtrich, U.6
Holland, S.7
Pawson, T.8
Rubsamen-Waigmann, H.9
Strebhardt, K.10
-
44
-
-
0033601747
-
The Junction-Associated Protein AF-6 Interacts and Clusters with Specific Eph Receptor Tyrosine Kinases at Specialized Sites of Cell-Cell Contact in the Brain
-
Buchert, M.; Schneider, S.; Meskenaite, V.; Adams, M. T.; Canaani, E.; Baechi, T.; Moelling, K.; Hovens, C. M. The Junction-Associated Protein AF-6 Interacts and Clusters with Specific Eph Receptor Tyrosine Kinases at Specialized Sites of Cell-Cell Contact in the Brain. J. Cell Biol. 1999, 144, 361-371.
-
(1999)
J. Cell Biol
, vol.144
, pp. 361-371
-
-
Buchert, M.1
Schneider, S.2
Meskenaite, V.3
Adams, M.T.4
Canaani, E.5
Baechi, T.6
Moelling, K.7
Hovens, C.M.8
-
45
-
-
0033957905
-
The WIF Module
-
Patthy, L. The WIF Module. Trends Biochem. Sci. 2000, 25, 12-13.
-
(2000)
Trends Biochem. Sci
, vol.25
, pp. 12-13
-
-
Patthy, L.1
-
46
-
-
0037431230
-
Wnt-Mediated Axon Guidance Via the Drosophila Derailed Receptor
-
Yoshikawa, S.; McKinnon, R. D.; Kokel, M.; Thomas, J. B. Wnt-Mediated Axon Guidance Via the Drosophila Derailed Receptor. Nature 2003, 422, 583-588.
-
(2003)
Nature
, vol.422
, pp. 583-588
-
-
Yoshikawa, S.1
McKinnon, R.D.2
Kokel, M.3
Thomas, J.B.4
-
47
-
-
34250862068
-
Different Wnt Signals Act Through the Frizzled and RYK Receptors During Drosophila Salivary Gland Migration
-
Harris, K. E.; Beckendorf, S. K. Different Wnt Signals Act Through the Frizzled and RYK Receptors During Drosophila Salivary Gland Migration. Development 2007, 134, 2017-2025.
-
(2007)
Development
, vol.134
, pp. 2017-2025
-
-
Harris, K.E.1
Beckendorf, S.K.2
-
48
-
-
34848850420
-
Respective Roles of the DRL Receptor and Its Ligand WNT5 in Drosophila Mushroom Body Development
-
Grillenzoni, N.; Flandre, A.; Lasbleiz, C.; Dura, J. M. Respective Roles of the DRL Receptor and Its Ligand WNT5 in Drosophila Mushroom Body Development. Development 2007, 134, 3089-3097.
-
(2007)
Development
, vol.134
, pp. 3089-3097
-
-
Grillenzoni, N.1
Flandre, A.2
Lasbleiz, C.3
Dura, J.M.4
-
49
-
-
35548980526
-
Antagonistic Roles of Wnt5 and the Drl Receptor in Patterning the Drosophila Antennal Lobe
-
Yao, Y.; Wu, Y.; Yin, C.; Ozawa, R.; Aigaki, T.; Wouda, R. R.; Noordermeer, J. N.; Fradkin, L. G.; Hing, H. Antagonistic Roles of Wnt5 and the Drl Receptor in Patterning the Drosophila Antennal Lobe. Nat. Neurosci. 2007, 10, 1423-1432.
-
(2007)
Nat. Neurosci
, vol.10
, pp. 1423-1432
-
-
Yao, Y.1
Wu, Y.2
Yin, C.3
Ozawa, R.4
Aigaki, T.5
Wouda, R.R.6
Noordermeer, J.N.7
Fradkin, L.G.8
Hing, H.9
-
50
-
-
3342926026
-
The Drosophila Wnt5 Protein Mediates Selective Axon Fasciculation in the Embryonic Central Nervous System
-
Fradkin, L. G.; van Schie, M.; Wouda, R. R.; de Jong, A.; Kamphorst, J. T.; Radjkoemar-Bansraj, M.; Noordermeer, J. N. The Drosophila Wnt5 Protein Mediates Selective Axon Fasciculation in the Embryonic Central Nervous System. Dev. Biol. 2004, 272, 362-375.
-
(2004)
Dev. Biol
, vol.272
, pp. 362-375
-
-
Fradkin, L.G.1
van Schie, M.2
Wouda, R.R.3
de Jong, A.4
Kamphorst, J.T.5
Radjkoemar-Bansraj, M.6
Noordermeer, J.N.7
-
51
-
-
11844256435
-
J. lin-17/Frizzled and lin-18 Regulate POP-1/TCF-1 Localization and Cell Type Specification During C. elegans Vulval Development
-
Deshpande, R.; Inoue, T.; Priess, J. R.; Hill, R. J. lin-17/Frizzled and lin-18 Regulate POP-1/TCF-1 Localization and Cell Type Specification During C. elegans Vulval Development. Dev. Biol. 2005, 278, 118-129.
-
(2005)
Dev. Biol
, vol.278
, pp. 118-129
-
-
Deshpande, R.1
Inoue, T.2
Priess, J.R.3
Hill, R.4
-
52
-
-
37248999443
-
The C. elegans ROR Receptor Tyrosine Kinase, CAM-1, Non-Autonomously Inhibits the Wnt Pathway
-
Green, J. L.; Inoue, T.; Sternberg, P. W. The C. elegans ROR Receptor Tyrosine Kinase, CAM-1, Non-Autonomously Inhibits the Wnt Pathway. Development 2007, 134, 4053-4062.
-
(2007)
Development
, vol.134
, pp. 4053-4062
-
-
Green, J.L.1
Inoue, T.2
Sternberg, P.W.3
-
53
-
-
5344273899
-
Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth
-
Lu, W.; Yamamoto, V.; Ortega, B.; Baltimore, D. Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth. Cell 2004, 119, 97-108.
-
(2004)
Cell
, vol.119
, pp. 97-108
-
-
Lu, W.1
Yamamoto, V.2
Ortega, B.3
Baltimore, D.4
-
54
-
-
27744605861
-
Ryk-Mediated Wnt Repulsion Regulates Posterior-Directed Growth of Corticospinal Tract
-
Liu, Y.; Shi, J.; Lu, C. C.; Wang, Z. B.; Lyuksyutova, A. I.; Song, X.; Zou, Y. Ryk-Mediated Wnt Repulsion Regulates Posterior-Directed Growth of Corticospinal Tract. Nat. Neurosci. 2005, 8, 1151-1159.
-
(2005)
Nat. Neurosci
, vol.8
, pp. 1151-1159
-
-
Liu, Y.1
Shi, J.2
Lu, C.C.3
Wang, Z.B.4
Lyuksyutova, A.I.5
Song, X.6
Zou, Y.7
-
55
-
-
30144433685
-
Wnt-Ryk Signalling Mediates Medial-Lateral Retinotectal Topographic Mapping
-
Schmitt, A. M.; Shi, J.; Wolf, A. M.; Lu, C. C.; King, L. A.; Zou, Y. Wnt-Ryk Signalling Mediates Medial-Lateral Retinotectal Topographic Mapping. Nature 2006, 439, 31-37.
-
(2006)
Nature
, vol.439
, pp. 31-37
-
-
Schmitt, A.M.1
Shi, J.2
Wolf, A.M.3
Lu, C.C.4
King, L.A.5
Zou, Y.6
-
56
-
-
33646241997
-
Purified Wnt5a Protein Activates or Inhibits Beta-Catenin-TCF Signaling Depending on Receptor Context
-
Mikels, A. J.; Nusse, R. Purified Wnt5a Protein Activates or Inhibits Beta-Catenin-TCF Signaling Depending on Receptor Context. PLoS Biol. 2006, 4, e115.
-
(2006)
PLoS Biol
, vol.4
-
-
Mikels, A.J.1
Nusse, R.2
-
57
-
-
0032482447
-
The Frizzled CRD Domain Is Conserved in Diverse Proteins Including Several Receptor Tyrosine Kinases
-
Xu, Y. K.; Nusse, R. The Frizzled CRD Domain Is Conserved in Diverse Proteins Including Several Receptor Tyrosine Kinases. Curr. Biol. 1998, 8, R405-R406.
-
(1998)
Curr. Biol
, vol.8
-
-
Xu, Y.K.1
Nusse, R.2
-
58
-
-
0032482322
-
The Wnt Receptor CRD Domain Is Also Found in MuSK and Related Orphan Receptor Tyrosine Kinases
-
Masiakowski, P.; Yancopoulos, G. D. The Wnt Receptor CRD Domain Is Also Found in MuSK and Related Orphan Receptor Tyrosine Kinases. Curr. Biol. 1998, 8, R407.
-
(1998)
Curr. Biol
, vol.8
-
-
Masiakowski, P.1
Yancopoulos, G.D.2
-
59
-
-
10744219743
-
The Receptor Tyrosine Kinase Ror2 Is Involved in Non-Canonical Wnt5a/JNK Signalling Pathway
-
Oishi, I.; Suzuki, H.; Onishi, N.; Takada, R.; Kani, S.; Ohkawara, B.; Koshida, I.; Suzuki, K.; Yamada, G.; Schwabe, G. C.; Mundlos, S.; Shibuya, H.; Takada, S.; Minami, Y. The Receptor Tyrosine Kinase Ror2 Is Involved in Non-Canonical Wnt5a/JNK Signalling Pathway. Genes Cells 2003, 8, 645-654.
-
(2003)
Genes Cells
, vol.8
, pp. 645-654
-
-
Oishi, I.1
Suzuki, H.2
Onishi, N.3
Takada, R.4
Kani, S.5
Ohkawara, B.6
Koshida, I.7
Suzuki, K.8
Yamada, G.9
Schwabe, G.C.10
Mundlos, S.11
Shibuya, H.12
Takada, S.13
Minami, Y.14
-
60
-
-
11244354521
-
The Orphan Receptor Tyrosine Kinase Ror2 Modulates Canonical Wnt Signaling in Osteoblastic Cells
-
Billiard, J.; Way, D. S.; Seestaller-Wehr, L. M.; Moran, R. A.; Mangine, A.; Bodine, P. V. The Orphan Receptor Tyrosine Kinase Ror2 Modulates Canonical Wnt Signaling in Osteoblastic Cells. Mol. Endocrinol. 2005, 19, 90-101.
-
(2005)
Mol. Endocrinol
, vol.19
, pp. 90-101
-
-
Billiard, J.1
Way, D.S.2
Seestaller-Wehr, L.M.3
Moran, R.A.4
Mangine, A.5
Bodine, P.V.6
-
61
-
-
34247589181
-
Wnt-5A/Ror2 Regulate Expression of XPAPC Through an Alternative Noncanonical Signaling Pathway
-
Schambony, A.; Wedlich, D. Wnt-5A/Ror2 Regulate Expression of XPAPC Through an Alternative Noncanonical Signaling Pathway. Dev. Cell 2007, 12, 779-792.
-
(2007)
Dev. Cell
, vol.12
, pp. 779-792
-
-
Schambony, A.1
Wedlich, D.2
-
62
-
-
34547103285
-
Wnt5a Secretion Stimulated by the Extracellular Calcium-Sensing Receptor Inhibits Defective Wnt Signaling in Colon Cancer Cells
-
MacLeod, R. J.; Hayes, M.; Pacheco, I. Wnt5a Secretion Stimulated by the Extracellular Calcium-Sensing Receptor Inhibits Defective Wnt Signaling in Colon Cancer Cells. Am. J. Physiol. 2007, 293, G403-G411.
-
(2007)
Am. J. Physiol
, vol.293
-
-
MacLeod, R.J.1
Hayes, M.2
Pacheco, I.3
-
63
-
-
33751215213
-
Filopodia Formation Mediated by Receptor Tyrosine Kinase Ror2 Is Required for Wnt5a-Induced Cell Migration
-
Nishita, M.; Yoo, S. K.; Nomachi, A.; Kani, S.; Sougawa, N.; Ohta, Y.; Takada, S.; Kikuchi, A.; Minami, Y. Filopodia Formation Mediated by Receptor Tyrosine Kinase Ror2 Is Required for Wnt5a-Induced Cell Migration. J. Cell Biol. 2006, 175, 555-562.
-
(2006)
J. Cell Biol
, vol.175
, pp. 555-562
-
-
Nishita, M.1
Yoo, S.K.2
Nomachi, A.3
Kani, S.4
Sougawa, N.5
Ohta, Y.6
Takada, S.7
Kikuchi, A.8
Minami, Y.9
-
64
-
-
0036166289
-
-
Yamanaka, H.; Moriguchi, T.; Masuyama, N.; Kusakabe, M.; Hanafusa, H.; Takada, R.; Takada, S.; Nishida, E. JNK Functions in the Non-Canonical Wnt Pathway to Regulate Convergent Extension Movements in Vertebrates. EMBO Rep. 2002, 3, 69-75.
-
Yamanaka, H.; Moriguchi, T.; Masuyama, N.; Kusakabe, M.; Hanafusa, H.; Takada, R.; Takada, S.; Nishida, E. JNK Functions in the Non-Canonical Wnt Pathway to Regulate Convergent Extension Movements in Vertebrates. EMBO Rep. 2002, 3, 69-75.
-
-
-
-
65
-
-
0021744029
-
Structure and Nucleotide Sequence of the Putative Mammary Oncogene int-1; Proviral Insertions Leave the Protein-Encoding Domain Intact
-
van Ooyen, A.; Nusse, R. Structure and Nucleotide Sequence of the Putative Mammary Oncogene int-1; Proviral Insertions Leave the Protein-Encoding Domain Intact. Cell 1984, 39, 233-240.
-
(1984)
Cell
, vol.39
, pp. 233-240
-
-
van Ooyen, A.1
Nusse, R.2
-
66
-
-
0020216124
-
Many Tumors Induced by the Mouse Mammary Tumor Virus Contain a Provirus Integrated in the Same Region of the Host Genome
-
Nusse, R.; Varmus, H. E. Many Tumors Induced by the Mouse Mammary Tumor Virus Contain a Provirus Integrated in the Same Region of the Host Genome. Cell 1982, 31, 99-109.
-
(1982)
Cell
, vol.31
, pp. 99-109
-
-
Nusse, R.1
Varmus, H.E.2
-
67
-
-
3142590865
-
Wnt Signaling and Breast Cancer
-
Howe, L. R.; Brown, A. M. Wnt Signaling and Breast Cancer. Cancer Biol. Ther. 2004, 3, 36-41.
-
(2004)
Cancer Biol. Ther
, vol.3
, pp. 36-41
-
-
Howe, L.R.1
Brown, A.M.2
-
68
-
-
0036528247
-
Wnt5a Signaling Directly Affects Cell Motility and Invasion of Metastatic Melanoma
-
Weeraratna, A. T.; Jiang, Y.; Hostetter, G.; Rosenblatt, K.; Duray, P.; Bittner, M.; Trent, J. M. Wnt5a Signaling Directly Affects Cell Motility and Invasion of Metastatic Melanoma. Cancer Cell 2002, 1, 279-288.
-
(2002)
Cancer Cell
, vol.1
, pp. 279-288
-
-
Weeraratna, A.T.1
Jiang, Y.2
Hostetter, G.3
Rosenblatt, K.4
Duray, P.5
Bittner, M.6
Trent, J.M.7
-
69
-
-
33846193290
-
The Many Ways of Wnt in Cancer
-
Polakis, P. The Many Ways of Wnt in Cancer. Curr. Opin. Genet. Dev. 2007, 17, 45-51.
-
(2007)
Curr. Opin. Genet. Dev
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
70
-
-
0038359353
-
Caught up in a Wnt Storm: Wnt Signaling in Cancer
-
Giles, R. H.; van Es, J. H.; Clevers, H. Caught up in a Wnt Storm: Wnt Signaling in Cancer. Biochim. Biophys. Acta 2003, 1653, 1-24.
-
(2003)
Biochim. Biophys. Acta
, vol.1653
, pp. 1-24
-
-
Giles, R.H.1
van Es, J.H.2
Clevers, H.3
-
71
-
-
33845373278
-
Colorectal Cancer and Genetic Alterations in the Wnt Pathway
-
Segditsas, S.; Tomlinson, I. Colorectal Cancer and Genetic Alterations in the Wnt Pathway. Oncogene 2006, 25, 7531-7537.
-
(2006)
Oncogene
, vol.25
, pp. 7531-7537
-
-
Segditsas, S.1
Tomlinson, I.2
-
72
-
-
0036613250
-
A Genomic Screen for Genes Upregulated by Demethylation and Histone Deacetylase Inhibition in Human Colorectal Cancer
-
Suzuki, H.; Gabrielson, E.; Chen, W.; Anbazhagan, R.; van Engeland, M.; Weijenberg, M. P.; Herman, J. G.; Baylin, S. B. A Genomic Screen for Genes Upregulated by Demethylation and Histone Deacetylase Inhibition in Human Colorectal Cancer. Nat. Genet. 2002, 31, 141-149.
-
(2002)
Nat. Genet
, vol.31
, pp. 141-149
-
-
Suzuki, H.1
Gabrielson, E.2
Chen, W.3
Anbazhagan, R.4
van Engeland, M.5
Weijenberg, M.P.6
Herman, J.G.7
Baylin, S.B.8
-
73
-
-
10744229341
-
The Wnt Antagonist sFRP1 in Colorectal Tumorigenesis
-
Caldwell, G. M.; Jones, C.; Gensberg, K.; Jan, S.; Hardy, R. G.; Byrd, P.; Chughtai, S.; Wallis, Y.; Matthews, G. M.; Morton, D. G. The Wnt Antagonist sFRP1 in Colorectal Tumorigenesis. Cancer Res. 2004, 64, 883-888.
-
(2004)
Cancer Res
, vol.64
, pp. 883-888
-
-
Caldwell, G.M.1
Jones, C.2
Gensberg, K.3
Jan, S.4
Hardy, R.G.5
Byrd, P.6
Chughtai, S.7
Wallis, Y.8
Matthews, G.M.9
Morton, D.G.10
-
74
-
-
0141995804
-
WIF1, a Component of the Wnt Pathway, Is Down-Regulated in Prostate, Breast, Lung, and Bladder Cancer
-
Wissmann, C.; Wild, P. J.; Kaiser, S.; Roepcke, S.; Stoehr, R.; Woenckhaus, M.; Kristiansen, G.; Hsieh, J. C.; Hofstaedter, F.; Hartmann, A.; Knuechel, R.; Rosenthal, A.; Pilarsky, C. WIF1, a Component of the Wnt Pathway, Is Down-Regulated in Prostate, Breast, Lung, and Bladder Cancer. J. Pathol. 2003, 201, 204-212.
-
(2003)
J. Pathol
, vol.201
, pp. 204-212
-
-
Wissmann, C.1
Wild, P.J.2
Kaiser, S.3
Roepcke, S.4
Stoehr, R.5
Woenckhaus, M.6
Kristiansen, G.7
Hsieh, J.C.8
Hofstaedter, F.9
Hartmann, A.10
Knuechel, R.11
Rosenthal, A.12
Pilarsky, C.13
-
75
-
-
3142679453
-
Wnt Inhibitory Factor-1 Is Silenced by Promoter Hypermethylation in Human Lung Cancer
-
Mazieres, J.; He, B.; You, L.; Xu, Z.; Lee, A. Y.; Mikami, I.; Reguart, N.; Rosell, R.; McCormick, F.; Jablons, D. M. Wnt Inhibitory Factor-1 Is Silenced by Promoter Hypermethylation in Human Lung Cancer. Cancer Res. 2004, 64, 4717-4720.
-
(2004)
Cancer Res
, vol.64
, pp. 4717-4720
-
-
Mazieres, J.1
He, B.2
You, L.3
Xu, Z.4
Lee, A.Y.5
Mikami, I.6
Reguart, N.7
Rosell, R.8
McCormick, F.9
Jablons, D.M.10
-
76
-
-
33845359084
-
Function and Biological Roles of the Dickkopf Family of Wnt Modulators
-
Niehrs, C. Function and Biological Roles of the Dickkopf Family of Wnt Modulators. Oncogene 2006, 25, 7469-7481.
-
(2006)
Oncogene
, vol.25
, pp. 7469-7481
-
-
Niehrs, C.1
-
77
-
-
34147215025
-
Dickkopf-1 Is an Epigenetically Silenced Candidate Tumor Suppressor Gene in Medulloblastoma
-
Vibhakar, R.; Foltz, G.; Yoon, J. G.; Field, L.; Lee, H.; Ryu, G. Y.; Pierson, J.; Davidson, B.; Madan, A. Dickkopf-1 Is an Epigenetically Silenced Candidate Tumor Suppressor Gene in Medulloblastoma. Neuro Oncol. 2007, 9, 135-144.
-
(2007)
Neuro Oncol
, vol.9
, pp. 135-144
-
-
Vibhakar, R.1
Foltz, G.2
Yoon, J.G.3
Field, L.4
Lee, H.5
Ryu, G.Y.6
Pierson, J.7
Davidson, B.8
Madan, A.9
-
78
-
-
33747348443
-
Expression of Dickkopf Genes Is Strongly Reduced in Malignant Melanoma
-
Kuphal, S.; Lodermeyer, S.; Bataille, F.; Schuierer, M.; Hoang, B. H.; Bosserhoff, A. K. Expression of Dickkopf Genes Is Strongly Reduced in Malignant Melanoma. Oncogene 2006, 25, 5027-5036.
-
(2006)
Oncogene
, vol.25
, pp. 5027-5036
-
-
Kuphal, S.1
Lodermeyer, S.2
Bataille, F.3
Schuierer, M.4
Hoang, B.H.5
Bosserhoff, A.K.6
-
79
-
-
4344645096
-
Transcriptional Silencing of the Dickkopfs-3 (Dkk-3) Gene by CpG Hypermethylation in Acute Lymphoblastic Leukaemia
-
Roman-Gomez, J.; Jimenez-Velasco, A.; Agirre, X.; Castillejo, J. A.; Navarro, G.; Barrios, M.; Andreu, E. J.; Prosper, F.; Heiniger, A.; Torres, A. Transcriptional Silencing of the Dickkopfs-3 (Dkk-3) Gene by CpG Hypermethylation in Acute Lymphoblastic Leukaemia. Br. J. Cancer 2004, 91, 707-713.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 707-713
-
-
Roman-Gomez, J.1
Jimenez-Velasco, A.2
Agirre, X.3
Castillejo, J.A.4
Navarro, G.5
Barrios, M.6
Andreu, E.J.7
Prosper, F.8
Heiniger, A.9
Torres, A.10
-
80
-
-
33745765883
-
Epigenetic Inactivation of the Wnt Antagonist DICKKOPF-1 (DKK-1) Gene in Human Colorectal Cancer
-
Aguilera, O.; Fraga, M. F.; Ballestar, E.; Paz, M. F.; Herranz, M.; Espada, J.; Garcia, J. M.; Munoz, A.; Esteller, M.; Gonzalez-Sancho, J. M. Epigenetic Inactivation of the Wnt Antagonist DICKKOPF-1 (DKK-1) Gene in Human Colorectal Cancer. Oncogene 2006, 25, 4116-4121.
-
(2006)
Oncogene
, vol.25
, pp. 4116-4121
-
-
Aguilera, O.1
Fraga, M.F.2
Ballestar, E.3
Paz, M.F.4
Herranz, M.5
Espada, J.6
Garcia, J.M.7
Munoz, A.8
Esteller, M.9
Gonzalez-Sancho, J.M.10
-
81
-
-
0034732151
-
Dickkopf-1, an Inhibitor of the Wnt Signaling Pathway, Is Induced by p53
-
Wang, J.; Shou, J.; Chen, X. Dickkopf-1, an Inhibitor of the Wnt Signaling Pathway, Is Induced by p53. Oncogene 2000, 19, 1843-1848.
-
(2000)
Oncogene
, vol.19
, pp. 1843-1848
-
-
Wang, J.1
Shou, J.2
Chen, X.3
-
82
-
-
34447530928
-
c-Myc Transforms Human Mammary Epithelial Cells Through Repression of the Wnt Inhibitors DKK1 and SFRP1
-
Cowling, V. H.; D'Cruz, C. M.; Chodosh, L. A.; Cole, M. D. c-Myc Transforms Human Mammary Epithelial Cells Through Repression of the Wnt Inhibitors DKK1 and SFRP1. Mol. Cell. Biol. 2007, 27, 5135-5146.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 5135-5146
-
-
Cowling, V.H.1
D'Cruz, C.M.2
Chodosh, L.A.3
Cole, M.D.4
-
83
-
-
0027090114
-
Identification of a Novel Tyrosine Kinase Receptor-Like Molecule in Neuroblastomas
-
Maminta, M. L. D.; Williams, K. L.; Nakagawara, A.; Enger, K. T.; Guo, C.; Brodeur, G. M.; Deuel, T. F. Identification of a Novel Tyrosine Kinase Receptor-Like Molecule in Neuroblastomas. Biochem. Biophys. Res. Commun. 1992, 189, 1077-1083.
-
(1992)
Biochem. Biophys. Res. Commun
, vol.189
, pp. 1077-1083
-
-
Maminta, M.L.D.1
Williams, K.L.2
Nakagawara, A.3
Enger, K.T.4
Guo, C.5
Brodeur, G.M.6
Deuel, T.F.7
-
84
-
-
12144289595
-
High-Throughput Analysis of Genome-Wide Receptor Tyrosine Kinase Expression in Human Cancers Identifies Potential Novel Drug Targets
-
Muller-Tidow, C.; Schwable, J.; Steffen, B.; Tidow, N.; Brandt, B.; Becker, K.; Schulze-Bahr, E.; Halfter, H.; Vogt, U.; Metzger, R.; Schneider, P. M.; Buchner, T.; Brandts, C.; Berdel, W. E.; Serve, H. High-Throughput Analysis of Genome-Wide Receptor Tyrosine Kinase Expression in Human Cancers Identifies Potential Novel Drug Targets. Clin. Cancer Res. 2004, 10, 1241-1249.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 1241-1249
-
-
Muller-Tidow, C.1
Schwable, J.2
Steffen, B.3
Tidow, N.4
Brandt, B.5
Becker, K.6
Schulze-Bahr, E.7
Halfter, H.8
Vogt, U.9
Metzger, R.10
Schneider, P.M.11
Buchner, T.12
Brandts, C.13
Berdel, W.E.14
Serve, H.15
-
85
-
-
33646437486
-
ICI 182,780-Regulated Gene Expression in DU145 Prostate Cancer Cells Is Mediated by Estrogen Receptor-Beta/NFkappaB Crosstalk
-
Leung, Y. K.; Gao, Y.; Lau, K. M.; Zhang, X.; Ho, S. M. ICI 182,780-Regulated Gene Expression in DU145 Prostate Cancer Cells Is Mediated by Estrogen Receptor-Beta/NFkappaB Crosstalk. Neoplasia 2006, 8, 242-249.
-
(2006)
Neoplasia
, vol.8
, pp. 242-249
-
-
Leung, Y.K.1
Gao, Y.2
Lau, K.M.3
Zhang, X.4
Ho, S.M.5
-
86
-
-
0033563245
-
Overexpression of H-Ryk in Mouse Fibroblasts Confers Transforming Ability In vitro and In vivo: Correlation with Up-Regulation in Epithelial Ovarian Cancer
-
Katso, R. M.; Manek, S.; Biddolph, S.; Whittaker, R.; Charnock, M. F.; Wells, M.; Ganesan, T. S. Overexpression of H-Ryk in Mouse Fibroblasts Confers Transforming Ability In vitro and In vivo: Correlation with Up-Regulation in Epithelial Ovarian Cancer. Cancer Res. 1999, 59, 2265-2270.
-
(1999)
Cancer Res
, vol.59
, pp. 2265-2270
-
-
Katso, R.M.1
Manek, S.2
Biddolph, S.3
Whittaker, R.4
Charnock, M.F.5
Wells, M.6
Ganesan, T.S.7
-
87
-
-
0033871087
-
Overexpression of HRyk in Epithelial Ovarian Cancer: Prognostic Significance of Receptor Expression
-
Katso, R. M.; Manek, S.; Ganjavi, H.; Biddolph, S.; Charnock, M. F.; Bradburn, M.; Wells, M.; Ganesan, T. S. Overexpression of HRyk in Epithelial Ovarian Cancer: Prognostic Significance of Receptor Expression. Clin. Cancer Res. 2000, 6, 3271-3281.
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 3271-3281
-
-
Katso, R.M.1
Manek, S.2
Ganjavi, H.3
Biddolph, S.4
Charnock, M.F.5
Bradburn, M.6
Wells, M.7
Ganesan, T.S.8
-
88
-
-
27744528481
-
Comparative Genomics on ROR1 and ROR2 Orthologs
-
Katoh, M.; Katoh, M. Comparative Genomics on ROR1 and ROR2 Orthologs. Oncol. Rep. 2005, 14, 1381-1384.
-
(2005)
Oncol. Rep
, vol.14
, pp. 1381-1384
-
-
Katoh, M.1
Katoh, M.2
-
89
-
-
34247627458
-
Expression and Mutation Status of Candidate Kinases in Multiple Myeloma
-
Claudio, J. O.; Zhan, F.; Zhuang, L.; Khaja, R.; Zhu, Y. X.; Sivananthan, K.; Trudel, S.; Masih-Khan, E.; Fonseca, R.; Bergsagel, P. L.; Scherer, S. W.; Shaughnessy, J.; Stewart, A. K. Expression and Mutation Status of Candidate Kinases in Multiple Myeloma. Leukemia 2007, 21, 1124-1127.
-
(2007)
Leukemia
, vol.21
, pp. 1124-1127
-
-
Claudio, J.O.1
Zhan, F.2
Zhuang, L.3
Khaja, R.4
Zhu, Y.X.5
Sivananthan, K.6
Trudel, S.7
Masih-Khan, E.8
Fonseca, R.9
Bergsagel, P.L.10
Scherer, S.W.11
Shaughnessy, J.12
Stewart, A.K.13
-
90
-
-
0034009511
-
Dominant Mutations in ROR2, Encoding an Orphan Receptor Tyrosine Kinase, Cause Brachydactyly Type B
-
Oldridge, M.; Fortuna, A. M.; Maringa, M.; Propping, P.; Mansour, S.; Pollitt, C.; DeChiara, T. M.; Kimble, R. B.; Valenzuela, D. M.; Yancopoulos, G. D.; Wilkie, A. O. Dominant Mutations in ROR2, Encoding an Orphan Receptor Tyrosine Kinase, Cause Brachydactyly Type B. Nat. Genet. 2000, 24, 275-278.
-
(2000)
Nat. Genet
, vol.24
, pp. 275-278
-
-
Oldridge, M.1
Fortuna, A.M.2
Maringa, M.3
Propping, P.4
Mansour, S.5
Pollitt, C.6
DeChiara, T.M.7
Kimble, R.B.8
Valenzuela, D.M.9
Yancopoulos, G.D.10
Wilkie, A.O.11
-
91
-
-
0029738843
-
Compartment Switching of WNT-2 Expression in Human Breast Tumors
-
Dale, T. C.; Weber-Hall, S. J.; Smith, K.; Huguet, E. L.; Jayatilake, H.; Gusterson, B. A.; Shuttleworth, G.; O'Hare, M.; Harris, A. L. Compartment Switching of WNT-2 Expression in Human Breast Tumors. Cancer Res. 1996, 56, 4320-4323.
-
(1996)
Cancer Res
, vol.56
, pp. 4320-4323
-
-
Dale, T.C.1
Weber-Hall, S.J.2
Smith, K.3
Huguet, E.L.4
Jayatilake, H.5
Gusterson, B.A.6
Shuttleworth, G.7
O'Hare, M.8
Harris, A.L.9
-
92
-
-
0032837683
-
Up-Regulation of Macrophage Wnt Gene Expression in Adenoma-Carcinoma Progression of Human Colorectal Cancer
-
Smith, K.; Bui, T. D.; Poulsom, R.; Kaklamanis, L.; Williams, G.; Harris, A. L. Up-Regulation of Macrophage Wnt Gene Expression in Adenoma-Carcinoma Progression of Human Colorectal Cancer. Br. J. Cancer 1999, 81, 496-502.
-
(1999)
Br. J. Cancer
, vol.81
, pp. 496-502
-
-
Smith, K.1
Bui, T.D.2
Poulsom, R.3
Kaklamanis, L.4
Williams, G.5
Harris, A.L.6
-
93
-
-
0030942879
-
Expression and Hormone Regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in Normal Human Endometrium and Endometrial Carcinoma
-
Bui, T. D.; Zhang, L.; Rees, M. C.; Bicknell, R.; Harris, A. L. Expression and Hormone Regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in Normal Human Endometrium and Endometrial Carcinoma. Br. J. Cancer 1997, 75, 1131-1136.
-
(1997)
Br. J. Cancer
, vol.75
, pp. 1131-1136
-
-
Bui, T.D.1
Zhang, L.2
Rees, M.C.3
Bicknell, R.4
Harris, A.L.5
-
94
-
-
0036733656
-
Pathway Pathology: Histological Differences between ErbB/Ras and Wnt Pathway Transgenic Mammary Tumors
-
Rosner, A.; Miyoshi, K.; Landesman-Bollag, E.; Xu, X.; Seldin, D. C.; Moser, A. R.; MacLeod, C. L.; Shyamala, G.; Gillgrass, A. E.; Cardiff, R. D. Pathway Pathology: Histological Differences between ErbB/Ras and Wnt Pathway Transgenic Mammary Tumors. Am. J. Pathol. 2002, 161, 1087-1097.
-
(2002)
Am. J. Pathol
, vol.161
, pp. 1087-1097
-
-
Rosner, A.1
Miyoshi, K.2
Landesman-Bollag, E.3
Xu, X.4
Seldin, D.C.5
Moser, A.R.6
MacLeod, C.L.7
Shyamala, G.8
Gillgrass, A.E.9
Cardiff, R.D.10
-
95
-
-
0032948879
-
Differential Expression of FrpHE: A Novel Human Stromal Protein of the Secreted Frizzled Gene Family, During the Endometrial Cycle and Malignancy
-
Abu-Jawdeh, G.; Comella, N.; Tomita, Y.; Brown, L. F.; Tognazzi, K.; Sokol, S. Y.; Kocher, O. Differential Expression of FrpHE: A Novel Human Stromal Protein of the Secreted Frizzled Gene Family, During the Endometrial Cycle and Malignancy. Lab. Invest. 1999, 79, 439-447.
-
(1999)
Lab. Invest
, vol.79
, pp. 439-447
-
-
Abu-Jawdeh, G.1
Comella, N.2
Tomita, Y.3
Brown, L.F.4
Tognazzi, K.5
Sokol, S.Y.6
Kocher, O.7
-
96
-
-
28544445306
-
Identification of SFRP1 as a Candidate Mediator of Stromal-to-Epithelial Signaling in Prostate Cancer
-
Joesting, M. S.; Perrin, S.; Elenbaas, B.; Fawell, S. E.; Rubin, J. S.; Franco, O. E.; Hayward, S. W.; Cunha, G. R.; Marker, P. C. Identification of SFRP1 as a Candidate Mediator of Stromal-to-Epithelial Signaling in Prostate Cancer. Cancer Res. 2005, 65, 10423-10430.
-
(2005)
Cancer Res
, vol.65
, pp. 10423-10430
-
-
Joesting, M.S.1
Perrin, S.2
Elenbaas, B.3
Fawell, S.E.4
Rubin, J.S.5
Franco, O.E.6
Hayward, S.W.7
Cunha, G.R.8
Marker, P.C.9
-
97
-
-
34548008809
-
Production of Wnt Inhibitors by Myeloma Cells: Potential Effects on Canonical Wnt Pathway in the Bone Microenvironment
-
Giuliani, N.; Morandi, F.; Tagliaferri, S.; Lazzaretti, M.; Donofrio, G.; Bonomini, S.; Sala, R.; Mangoni, M.; Rizzoli, V. Production of Wnt Inhibitors by Myeloma Cells: Potential Effects on Canonical Wnt Pathway in the Bone Microenvironment. Cancer Res. 2007, 67, 7665-7674.
-
(2007)
Cancer Res
, vol.67
, pp. 7665-7674
-
-
Giuliani, N.1
Morandi, F.2
Tagliaferri, S.3
Lazzaretti, M.4
Donofrio, G.5
Bonomini, S.6
Sala, R.7
Mangoni, M.8
Rizzoli, V.9
-
98
-
-
4644302254
-
Dickkopf-1 Antagonizes Wnt Signaling Independent of Beta-Catenin in Human Mesothelioma
-
Lee, A. Y.; He, B.; You, L.; Xu, Z.; Mazieres, J.; Reguart, N.; Mikami, I.; Batra, S.; Jablons, D. M. Dickkopf-1 Antagonizes Wnt Signaling Independent of Beta-Catenin in Human Mesothelioma. Biochem. Biophys. Res. Commun. 2004, 323, 1246-1250.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.323
, pp. 1246-1250
-
-
Lee, A.Y.1
He, B.2
You, L.3
Xu, Z.4
Mazieres, J.5
Reguart, N.6
Mikami, I.7
Batra, S.8
Jablons, D.M.9
-
99
-
-
27544457678
-
Adenovirus-Mediated Overexpression of REIC/Dkk-3 Selectively Induces Apoptosis in Human Prostate Cancer Cells Through Activation of c-Jun-NH2-Kinase
-
Abarzua, F.; Sakaguchi, M.; Takaishi, M.; Nasu, Y.; Kurose, K.; Ebara, S.; Miyazaki, M.; Namba, M.; Kumon, H.; Huh, N. H. Adenovirus-Mediated Overexpression of REIC/Dkk-3 Selectively Induces Apoptosis in Human Prostate Cancer Cells Through Activation of c-Jun-NH2-Kinase. Cancer Res. 2005, 65, 9617-9622.
-
(2005)
Cancer Res
, vol.65
, pp. 9617-9622
-
-
Abarzua, F.1
Sakaguchi, M.2
Takaishi, M.3
Nasu, Y.4
Kurose, K.5
Ebara, S.6
Miyazaki, M.7
Namba, M.8
Kumon, H.9
Huh, N.H.10
-
100
-
-
33749630747
-
Dickkopf-1 Induced Apoptosis in Human Placental Choriocarcinoma Is Independent of Canonical Wnt Signaling
-
Peng, S.; Miao, C.; Li, J.; Fan, X.; Cao, Y.; Duan, E. Dickkopf-1 Induced Apoptosis in Human Placental Choriocarcinoma Is Independent of Canonical Wnt Signaling. Biochem. Biophys. Res. Commun. 2006, 350, 641-647.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.350
, pp. 641-647
-
-
Peng, S.1
Miao, C.2
Li, J.3
Fan, X.4
Cao, Y.5
Duan, E.6
-
101
-
-
13944282066
-
The Wnt Antagonist DICKKOPF-1 Gene Is a Downstream Target of Beta-Catenin/TCF and Is Downregulated in Human Colon Cancer
-
Gonzalez-Sancho, J. M.; Aguilera, O.; Garcia, J. M.; Pendas-Franco, N.; Pena, C.; Cal, S.; Garcia de Herreros, A.; Bonilla, F.; Munoz, A. The Wnt Antagonist DICKKOPF-1 Gene Is a Downstream Target of Beta-Catenin/TCF and Is Downregulated in Human Colon Cancer. Oncogene 2005, 24, 1098-1103.
-
(2005)
Oncogene
, vol.24
, pp. 1098-1103
-
-
Gonzalez-Sancho, J.M.1
Aguilera, O.2
Garcia, J.M.3
Pendas-Franco, N.4
Pena, C.5
Cal, S.6
Garcia de Herreros, A.7
Bonilla, F.8
Munoz, A.9
-
102
-
-
0036207721
-
The Wnt Pathway, Epithelial-Stromal Interactions, and Malignant Progression in Phyllodes Tumours
-
Sawyer, E. J.; Hanby, A. M.; Rowan, A. J.; Gillett, C. E.; Thomas, R. E.; Poulsom, R.; Lakhani, S. R.; Ellis, I. O.; Ellis, P.; Tomlinson, I. P. The Wnt Pathway, Epithelial-Stromal Interactions, and Malignant Progression in Phyllodes Tumours. J. Pathol. 2002, 196, 437-444.
-
(2002)
J. Pathol
, vol.196
, pp. 437-444
-
-
Sawyer, E.J.1
Hanby, A.M.2
Rowan, A.J.3
Gillett, C.E.4
Thomas, R.E.5
Poulsom, R.6
Lakhani, S.R.7
Ellis, I.O.8
Ellis, P.9
Tomlinson, I.P.10
-
103
-
-
33745494534
-
-
Gunn, W. G.; Conley, A.; Deininger, L.; Olson, S. D.; Prockop, D. J.; Gregory, C. A. A Crosstalk between Myeloma Cells and Marrow Stromal Cells Stimulates Production of DKK1 and Interleukin-6: A Potential Role in the Development of Lytic Bone Disease and Tumor Progression in Multiple Myeloma. Stem Cells 2006, 24, 986-991.
-
Gunn, W. G.; Conley, A.; Deininger, L.; Olson, S. D.; Prockop, D. J.; Gregory, C. A. A Crosstalk between Myeloma Cells and Marrow Stromal Cells Stimulates Production of DKK1 and Interleukin-6: A Potential Role in the Development of Lytic Bone Disease and Tumor Progression in Multiple Myeloma. Stem Cells 2006, 24, 986-991.
-
-
-
-
104
-
-
34250733015
-
Wnt3/RhoA/ROCK Signaling Pathway Is Involved in Adhesion-Mediated Drug Resistance of Multiple Myeloma in an Autocrine Mechanism
-
Kobune, M.; Chiba, H.; Kato, J.; Kato, K.; Nakamura, K.; Kawano, Y.; Takada, K.; Takimoto, R.; Takayama, T.; Hamada, H.; Niitsu, Y. Wnt3/RhoA/ROCK Signaling Pathway Is Involved in Adhesion-Mediated Drug Resistance of Multiple Myeloma in an Autocrine Mechanism. Mol. Cancer Ther. 2007, 6, 1774-1784.
-
(2007)
Mol. Cancer Ther
, vol.6
, pp. 1774-1784
-
-
Kobune, M.1
Chiba, H.2
Kato, J.3
Kato, K.4
Nakamura, K.5
Kawano, Y.6
Takada, K.7
Takimoto, R.8
Takayama, T.9
Hamada, H.10
Niitsu, Y.11
-
105
-
-
36148972831
-
Ph+/VECadherin+ Identifies a Stem Cell Like Population of Acute Lymphoblastic Leukemia Sustained by Bone Marrow Niche Cells
-
Wang, L.; O'Leary, H.; Fortney, J.; Gibson, L. F. Ph+/VECadherin+ Identifies a Stem Cell Like Population of Acute Lymphoblastic Leukemia Sustained by Bone Marrow Niche Cells. Blood 2007, 110, 3334-3344.
-
(2007)
Blood
, vol.110
, pp. 3334-3344
-
-
Wang, L.1
O'Leary, H.2
Fortney, J.3
Gibson, L.F.4
-
106
-
-
33744472747
-
Wnt/Frizzled Signaling in the Vasculature: New Angiogenic Factors in Sight
-
Masckauchan, T. N.; Kitajewski, J. Wnt/Frizzled Signaling in the Vasculature: New Angiogenic Factors in Sight. Physiology 2006, 21, 181-188.
-
(2006)
Physiology
, vol.21
, pp. 181-188
-
-
Masckauchan, T.N.1
Kitajewski, J.2
-
107
-
-
0033600729
-
Identification of a Wnt-Responsive Signal Transduction Pathway in Primary Endothelial Cells
-
Wright, M.; Aikawa, M.; Szeto, W.; Papkoff, J. Identification of a Wnt-Responsive Signal Transduction Pathway in Primary Endothelial Cells. Biochem. Biophys. Res. Commun. 1999, 263, 384-388.
-
(1999)
Biochem. Biophys. Res. Commun
, vol.263
, pp. 384-388
-
-
Wright, M.1
Aikawa, M.2
Szeto, W.3
Papkoff, J.4
-
108
-
-
24044500959
-
Wnt/Beta-Catenin Signaling Induces Proliferation, Survival and Interleukin-8 in Human Endothelial Cells
-
Masckauchan, T. N.; Shawber, C. J.; Funahashi, Y.; Li, C. M.; Kitajewski, J. Wnt/Beta-Catenin Signaling Induces Proliferation, Survival and Interleukin-8 in Human Endothelial Cells. Angiogenesis 2005, 8, 43-51.
-
(2005)
Angiogenesis
, vol.8
, pp. 43-51
-
-
Masckauchan, T.N.1
Shawber, C.J.2
Funahashi, Y.3
Li, C.M.4
Kitajewski, J.5
-
109
-
-
34247639507
-
Wnt1 and Wnt5a Affect Endothelial Proliferation and Capillary Length; Wnt2 Does Not
-
Goodwin, A. M.; Kitajewski, J.; D'Amore, P. A. Wnt1 and Wnt5a Affect Endothelial Proliferation and Capillary Length; Wnt2 Does Not. Growth Factors 2007, 25, 25-32.
-
(2007)
Growth Factors
, vol.25
, pp. 25-32
-
-
Goodwin, A.M.1
Kitajewski, J.2
D'Amore, P.A.3
-
110
-
-
34247642230
-
Wnts and BMPs Mediate Induction of VEGFR-2 (Quek-1) Expression During Avian Somite Development
-
Nimmagadda, S.; Geetha-Loganathan, P.; Scaal, M.; Christ, B.; Huang, R. FGFs, Wnts and BMPs Mediate Induction of VEGFR-2 (Quek-1) Expression During Avian Somite Development. Dev. Biol. 2007, 305, 421-429.
-
(2007)
Dev. Biol
, vol.305
, pp. 421-429
-
-
Nimmagadda, S.1
Geetha-Loganathan, P.2
Scaal, M.3
Christ, B.4
Huang5
FGFs, R.6
-
111
-
-
34249689753
-
Molecular Regulation of Angiogenesis and Lymphangiogenesis
-
Adams, R. H.; Alitalo, K. Molecular Regulation of Angiogenesis and Lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 2007, 8, 464-478.
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
112
-
-
19944403876
-
Wnt/Beta-Catenin Signaling Pathway as a Novel Cancer Drug Target
-
Luu, H. H.; Zhang, R.; Haydon, R. C.; Rayburn, E.; Kang, Q.; Si, W.; Park, J. K.; Wang, H.; Peng, Y.; Jiang, W.; He, T. C. Wnt/Beta-Catenin Signaling Pathway as a Novel Cancer Drug Target. Curr. Cancer Drug Targets 2004, 4, 653-671.
-
(2004)
Curr. Cancer Drug Targets
, vol.4
, pp. 653-671
-
-
Luu, H.H.1
Zhang, R.2
Haydon, R.C.3
Rayburn, E.4
Kang, Q.5
Si, W.6
Park, J.K.7
Wang, H.8
Peng, Y.9
Jiang, W.10
He, T.C.11
-
113
-
-
33751530490
-
Mining the Wnt Pathway for Cancer Therapeutics
-
Barker, N.; Clevers, H. Mining the Wnt Pathway for Cancer Therapeutics. Nat. Rev. Drug Discov. 2006, 5, 997-1014.
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
114
-
-
0037466434
-
Tyrosine Kinase Inhibitor STI-571/Gleevec Down-Regulates the Beta-Catenin Signaling Activity
-
Zhou, L.; An, N.; Haydon, R. C.; Zhou, Q.; Cheng, H.; Peng, Y.; Jiang, W.; Luu, H. H.; Vanichakarn, P.; Szatkowski, J. P.; Park, J. Y.; Breyer, B.; He, T. C. Tyrosine Kinase Inhibitor STI-571/Gleevec Down-Regulates the Beta-Catenin Signaling Activity. Cancer Lett. 2003, 193, 161-170.
-
(2003)
Cancer Lett
, vol.193
, pp. 161-170
-
-
Zhou, L.1
An, N.2
Haydon, R.C.3
Zhou, Q.4
Cheng, H.5
Peng, Y.6
Jiang, W.7
Luu, H.H.8
Vanichakarn, P.9
Szatkowski, J.P.10
Park, J.Y.11
Breyer, B.12
He, T.C.13
-
115
-
-
0347481364
-
Trans-Repression of Beta-Catenin Activity by Nuclear Receptors
-
Shah, S.; Hecht, A.; Pestell, R.; Byers, S. W. Trans-Repression of Beta-Catenin Activity by Nuclear Receptors. J. Biol. Chem. 2003, 278, 48137-48145.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 48137-48145
-
-
Shah, S.1
Hecht, A.2
Pestell, R.3
Byers, S.W.4
-
116
-
-
33644850904
-
The Molecular Basis of Vitamin D Receptor and Beta-Catenin Crossregulation
-
Shah, S.; Islam, M. N.; Dakshanamurthy, S.; Rizvi, I.; Rao, M.; Herrell, R.; Zinser, G.; Valrance, M.; Aranda, A.; Moras, D.; Norman, A.; Welsh, J.; Byers, S. W. The Molecular Basis of Vitamin D Receptor and Beta-Catenin Crossregulation. Mol. Cell 2006, 21, 799-809.
-
(2006)
Mol. Cell
, vol.21
, pp. 799-809
-
-
Shah, S.1
Islam, M.N.2
Dakshanamurthy, S.3
Rizvi, I.4
Rao, M.5
Herrell, R.6
Zinser, G.7
Valrance, M.8
Aranda, A.9
Moras, D.10
Norman, A.11
Welsh, J.12
Byers, S.W.13
-
117
-
-
0842329914
-
Sulindac Targets Nuclear Beta-Catenin Accumulation and Wnt Signalling in Adenomas of Patients with Familial Adenomatous Polyposis and in Human Colorectal Cancer Cell Lines
-
Boon, E. M.; Keller, J. J.; Wormhoudt, T. A.; Giardiello, F. M.; Offerhaus, G. J.; van der Neut, R.; Pals, S. T. Sulindac Targets Nuclear Beta-Catenin Accumulation and Wnt Signalling in Adenomas of Patients with Familial Adenomatous Polyposis and in Human Colorectal Cancer Cell Lines. Br. J. Cancer 2004, 90, 224-229.
-
(2004)
Br. J. Cancer
, vol.90
, pp. 224-229
-
-
Boon, E.M.1
Keller, J.J.2
Wormhoudt, T.A.3
Giardiello, F.M.4
Offerhaus, G.J.5
van der Neut, R.6
Pals, S.T.7
-
119
-
-
1642512639
-
Small-Molecule Antagonists of the Oncogenic Tcf/Beta-Catenin Protein Complex
-
Lepourcelet, M.; Chen, Y. N.; France, D. S.; Wang, H.; Crews, P.; Petersen, F.; Bruseo, C.; Wood, A. W.; Shivdasani, R. A. Small-Molecule Antagonists of the Oncogenic Tcf/Beta-Catenin Protein Complex. Cancer Cell 2004, 5, 91-102.
-
(2004)
Cancer Cell
, vol.5
, pp. 91-102
-
-
Lepourcelet, M.1
Chen, Y.N.2
France, D.S.3
Wang, H.4
Crews, P.5
Petersen, F.6
Bruseo, C.7
Wood, A.W.8
Shivdasani, R.A.9
-
120
-
-
4344587136
-
A Small Molecule Inhibitor of Beta-Catenin/CREB-Binding Protein Transcription
-
Emami, K. H.; Nguyen, C.; Ma, H.; Kim, D. H.; Jeong, K. W.; Eguchi, M.; Moon, R. T.; Teo, J. L.; Kim, H. Y.; Moon, S. H.; Ha, J. R.; Kahn, M. A Small Molecule Inhibitor of Beta-Catenin/CREB-Binding Protein Transcription. Proc. Natl. Acad. Sci. USA 2004, 101, 12682-12687.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12682-12687
-
-
Emami, K.H.1
Nguyen, C.2
Ma, H.3
Kim, D.H.4
Jeong, K.W.5
Eguchi, M.6
Moon, R.T.7
Teo, J.L.8
Kim, H.Y.9
Moon, S.H.10
Ha, J.R.11
Kahn, M.12
-
121
-
-
1642494839
-
The Cyclin-Dependent Kinase Inhibitor Cyc202 (R-Roscovitine) Inhibits Retinoblastoma Protein Phosphorylation, Causes Loss of Cyclin D1, and Activates the Mitogen-Activated Protein Kinase Pathway
-
Whittaker, S. R.; Walton, M. I.; Garrett, M. D.; Workman, P. The Cyclin-Dependent Kinase Inhibitor Cyc202 (R-Roscovitine) Inhibits Retinoblastoma Protein Phosphorylation, Causes Loss of Cyclin D1, and Activates the Mitogen-Activated Protein Kinase Pathway. Cancer Res. 2004, 64, 262-272.
-
(2004)
Cancer Res
, vol.64
, pp. 262-272
-
-
Whittaker, S.R.1
Walton, M.I.2
Garrett, M.D.3
Workman, P.4
-
122
-
-
28244496603
-
Identification of a Specific Inhibitor of the Dishevelled PDZ Domain
-
Shan, J.; Shi, D. L.; Wang, J.; Zheng, J. Identification of a Specific Inhibitor of the Dishevelled PDZ Domain. Biochemistry 2005, 44, 15495-15503.
-
(2005)
Biochemistry
, vol.44
, pp. 15495-15503
-
-
Shan, J.1
Shi, D.L.2
Wang, J.3
Zheng, J.4
-
123
-
-
0034088858
-
AXIN1 Mutations in Hepatocellular Carcinomas, and Growth Suppression in Cancer Cells by Virus-Mediated Transfer of AXIN1
-
Satoh, S.; Daigo, Y.; Furukawa, Y.; Kato, T.; Miwa, N.; Nishiwaki, T.; Kawasoe, T.; Ishiguro, H.; Fujita, M.; Tokino, T.; Sasaki, Y.; Imaoka, S.; Murata, M.; Shimano, T.; Yamaoka, Y.; Nakamura, Y. AXIN1 Mutations in Hepatocellular Carcinomas, and Growth Suppression in Cancer Cells by Virus-Mediated Transfer of AXIN1. Nat. Genet. 2000, 24, 245-250.
-
(2000)
Nat. Genet
, vol.24
, pp. 245-250
-
-
Satoh, S.1
Daigo, Y.2
Furukawa, Y.3
Kato, T.4
Miwa, N.5
Nishiwaki, T.6
Kawasoe, T.7
Ishiguro, H.8
Fujita, M.9
Tokino, T.10
Sasaki, Y.11
Imaoka, S.12
Murata, M.13
Shimano, T.14
Yamaoka, Y.15
Nakamura, Y.16
-
124
-
-
0034653689
-
The Beta-Catenin Binding Domain of Adenomatous Polyposis Coli Is Sufficient for Tumor Suppression
-
Shih, I. M.; Yu, J.; He, T. C.; Vogelstein, B.; Kinzler, K. W. The Beta-Catenin Binding Domain of Adenomatous Polyposis Coli Is Sufficient for Tumor Suppression. Cancer Res. 2000, 60, 1671-1676.
-
(2000)
Cancer Res
, vol.60
, pp. 1671-1676
-
-
Shih, I.M.1
Yu, J.2
He, T.C.3
Vogelstein, B.4
Kinzler, K.W.5
-
125
-
-
0035420212
-
Suppression of Beta-Catenin Inhibits the Neoplastic Growth of APC-Mutant Colon Cancer Cells
-
Roh, H.; Green, D. W.; Boswell, C. B.; Pippin, J. A.; Drebin, J. A. Suppression of Beta-Catenin Inhibits the Neoplastic Growth of APC-Mutant Colon Cancer Cells. Cancer Res. 2001, 61, 6563-6568.
-
(2001)
Cancer Res
, vol.61
, pp. 6563-6568
-
-
Roh, H.1
Green, D.W.2
Boswell, C.B.3
Pippin, J.A.4
Drebin, J.A.5
-
126
-
-
0037388638
-
Small Interfering RNAs Directed against Beta-Catenin Inhibit the In vitro and In vivo Growth of Colon Cancer Cells
-
Verma, U. N.; Surabhi, R. M.; Schmaltieg, A.; Becerra, C.; Gaynor, R. B. Small Interfering RNAs Directed against Beta-Catenin Inhibit the In vitro and In vivo Growth of Colon Cancer Cells. Clin. Cancer Res. 2003, 9, 1291-1300.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 1291-1300
-
-
Verma, U.N.1
Surabhi, R.M.2
Schmaltieg, A.3
Becerra, C.4
Gaynor, R.B.5
-
127
-
-
0037479844
-
Efficacy of Antisense Morpholino Oligomer Targeted to c-Myc in Prostate Cancer Xenograft Murine Model and a Phase I Safety Study in Humans
-
Iversen, P. L.; Arora, V.; Acker, A. J.; Mason, D. H.; Devi, G. R. Efficacy of Antisense Morpholino Oligomer Targeted to c-Myc in Prostate Cancer Xenograft Murine Model and a Phase I Safety Study in Humans. Clin. Cancer Res. 2003, 9, 2510-2519.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 2510-2519
-
-
Iversen, P.L.1
Arora, V.2
Acker, A.J.3
Mason, D.H.4
Devi, G.R.5
-
128
-
-
3042853832
-
Optimization of a Synthetic Beta-Catenin-Dependent Promoter for Tumor-Specific Cancer Gene Therapy
-
Lipinski, K. S.; Djeha, H. A.; Gawn, J.; Cliffe, S.; Maitland, N. J.; Palmer, D. H.; Mountain, A.; Irvine, A. S.; Wrighton, C. J. Optimization of a Synthetic Beta-Catenin-Dependent Promoter for Tumor-Specific Cancer Gene Therapy. Mol. Ther. 2004, 10, 150-161.
-
(2004)
Mol. Ther
, vol.10
, pp. 150-161
-
-
Lipinski, K.S.1
Djeha, H.A.2
Gawn, J.3
Cliffe, S.4
Maitland, N.J.5
Palmer, D.H.6
Mountain, A.7
Irvine, A.S.8
Wrighton, C.J.9
-
129
-
-
0346458662
-
Essential Requirement for Wnt Signaling in Proliferation of Adult Small Intestine and Colon Revealed by Adenoviral Expression of Dickkopf-1
-
Kuhnert, F.; Davis, C. R.; Wang, H. T.; Chu, P.; Lee, M.; Yuan, J.; Nusse, R.; Kuo, C. J. Essential Requirement for Wnt Signaling in Proliferation of Adult Small Intestine and Colon Revealed by Adenoviral Expression of Dickkopf-1. Proc. Natl. Acad. Sci. USA 2004, 101, 266-271.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 266-271
-
-
Kuhnert, F.1
Davis, C.R.2
Wang, H.T.3
Chu, P.4
Lee, M.5
Yuan, J.6
Nusse, R.7
Kuo, C.J.8
-
130
-
-
1642341682
-
A Monoclonal Antibody against Wnt-1 Induces Apoptosis in Human Cancer Cells
-
He, B.; You, L.; Uematsu, K.; Xu, Z.; Lee, A. Y.; Matsangou, M.; McCormick, F.; Jablons, D. M. A Monoclonal Antibody against Wnt-1 Induces Apoptosis in Human Cancer Cells. Neoplasia 2004, 6, 7-14.
-
(2004)
Neoplasia
, vol.6
, pp. 7-14
-
-
He, B.1
You, L.2
Uematsu, K.3
Xu, Z.4
Lee, A.Y.5
Matsangou, M.6
McCormick, F.7
Jablons, D.M.8
-
131
-
-
18344377028
-
Blockade of Wnt-1 Signaling Induces Apoptosis in Human Colorectal Cancer Cells Containing Downstream Mutations
-
He, B.; Reguart, N.; You, L.; Mazieres, J.; Xu, Z.; Lee, A. Y.; Mikami, I.; McCormick, F.; Jablons, D. M. Blockade of Wnt-1 Signaling Induces Apoptosis in Human Colorectal Cancer Cells Containing Downstream Mutations. Oncogene 2005, 24, 3054-3058.
-
(2005)
Oncogene
, vol.24
, pp. 3054-3058
-
-
He, B.1
Reguart, N.2
You, L.3
Mazieres, J.4
Xu, Z.5
Lee, A.Y.6
Mikami, I.7
McCormick, F.8
Jablons, D.M.9
-
132
-
-
3442894128
-
An Anti-Wnt-2 Monoclonal Antibody Induces Apoptosis in Malignant Melanoma Cells and Inhibits Tumor Growth
-
You, L.; He, B.; Xu, Z.; Uematsu, K.; Mazieres, J.; Fujii, N.; Mikami, I.; Reguart, N.; McIntosh, J. K.; Kashani-Sabet, M.; McCormick, F.; Jablons, D. M. An Anti-Wnt-2 Monoclonal Antibody Induces Apoptosis in Malignant Melanoma Cells and Inhibits Tumor Growth. Cancer Res. 2004, 64, 5385-5389.
-
(2004)
Cancer Res
, vol.64
, pp. 5385-5389
-
-
You, L.1
He, B.2
Xu, Z.3
Uematsu, K.4
Mazieres, J.5
Fujii, N.6
Mikami, I.7
Reguart, N.8
McIntosh, J.K.9
Kashani-Sabet, M.10
McCormick, F.11
Jablons, D.M.12
-
133
-
-
26844569797
-
Efficacy of Wnt-1 Monoclonal Antibody in Sarcoma Cells
-
Mikami, I.; You, L.; He, B.; Xu, Z.; Batra, S.; Lee, A. Y.; Mazieres, J.; Reguart, N.; Uematsu, K.; Koizumi, K.; Jablons, D. M. Efficacy of Wnt-1 Monoclonal Antibody in Sarcoma Cells. BMC Cancer 2005, 5, 53.
-
(2005)
BMC Cancer
, vol.5
, pp. 53
-
-
Mikami, I.1
You, L.2
He, B.3
Xu, Z.4
Batra, S.5
Lee, A.Y.6
Mazieres, J.7
Reguart, N.8
Uematsu, K.9
Koizumi, K.10
Jablons, D.M.11
-
134
-
-
24044490922
-
Inhibition of Wnt16 in Human Acute Lymphoblastoid Leukemia Cells Containing the t(1;19) Translocation Induces Apoptosis
-
Mazieres, J.; You, L.; He, B.; Xu, Z.; Lee, A. Y.; Mikami, I.; McCormick, F.; Jablons, D. M. Inhibition of Wnt16 in Human Acute Lymphoblastoid Leukemia Cells Containing the t(1;19) Translocation Induces Apoptosis. Oncogene 2005, 24, 5396-5400.
-
(2005)
Oncogene
, vol.24
, pp. 5396-5400
-
-
Mazieres, J.1
You, L.2
He, B.3
Xu, Z.4
Lee, A.Y.5
Mikami, I.6
McCormick, F.7
Jablons, D.M.8
-
135
-
-
25444496522
-
Wnt2 as a New Therapeutic Target in Malignant Pleural Mesothelioma
-
Mazieres, J.; You, L.; He, B.; Xu, Z.; Twogood, S.; Lee, A. Y.; Reguart, N.; Batra, S.; Mikami, I.; Jablons, D. M. Wnt2 as a New Therapeutic Target in Malignant Pleural Mesothelioma. Int. J. Cancer 2005, 117, 326-332.
-
(2005)
Int. J. Cancer
, vol.117
, pp. 326-332
-
-
Mazieres, J.1
You, L.2
He, B.3
Xu, Z.4
Twogood, S.5
Lee, A.Y.6
Reguart, N.7
Batra, S.8
Mikami, I.9
Jablons, D.M.10
-
136
-
-
34548079518
-
Inhibition of Wnt-2 and Galectin-3 Synergistically Destabilizes Beta-Catenin and Induces Apoptosis in Human Colorectal Cancer Cells
-
Shi, Y.; He, B.; Kuchenbecker, K. M.; You, L.; Xu, Z.; Mikami, I.; Yagui-Beltran, A.; Clement, G.; Lin, Y. C.; Okamoto, J.; Bravo, D. T.; Jablons, D. M. Inhibition of Wnt-2 and Galectin-3 Synergistically Destabilizes Beta-Catenin and Induces Apoptosis in Human Colorectal Cancer Cells. Int. J. Cancer 2007, 121, 1175-1181.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 1175-1181
-
-
Shi, Y.1
He, B.2
Kuchenbecker, K.M.3
You, L.4
Xu, Z.5
Mikami, I.6
Yagui-Beltran, A.7
Clement, G.8
Lin, Y.C.9
Okamoto, J.10
Bravo, D.T.11
Jablons, D.M.12
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