-
1
-
-
0037428102
-
Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk
-
Abtahian, F., A. Guerriero, E. Sebzda, M.M. Lu, R. Zhou, A. Mocsai, E.E. Myers, B. Huang, D.G. Jackson, V.A. Ferrari, et al. 2003. Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk. Science. 299:247-251.
-
(2003)
Science
, vol.299
, pp. 247-251
-
-
Abtahian, F.1
Guerriero, A.2
Sebzda, E.3
Lu, M.M.4
Zhou, R.5
Mocsai, A.6
Myers, E.E.7
Huang, B.8
Jackson, D.G.9
Ferrari, V.A.10
-
3
-
-
70649091987
-
Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans
-
Alders, M., B.M. Hogan, E. Gjini, F. Salehi, L. Al-Gazali, E.A. Hennekam, E.E. Holmberg, M.M. Mannens, M.F. Mulder, G.J. Offerhaus, et al. 2009. Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans. Nat. Genet. 41:1272-1274.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1272-1274
-
-
Alders, M.1
Hogan, B.M.2
Gjini, E.3
Salehi, F.4
Al-Gazali, L.5
Hennekam, E.A.6
Holmberg, E.E.7
Mannens, M.M.8
Mulder, M.F.9
Offerhaus, G.J.10
-
4
-
-
77956385127
-
Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humans
-
Au, A.C., P.A. Hernandez, E. Lieber, A.M. Nadroo, Y.M. Shen, K.A. Kelley, B.D. Gelb, and G.A. Diaz. 2010. Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humans. Am. J. Hum. Genet. 87:436-444.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 436-444
-
-
Au, A.C.1
Hernandez, P.A.2
Lieber, E.3
Nadroo, A.M.4
Shen, Y.M.5
Kelley, K.A.6
Gelb, B.D.7
Diaz, G.A.8
-
5
-
-
0035903656
-
Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1
-
Ayadi, A., H. Zheng, P. Sobieszczuk, G. Buchwalter, P. Moerman, K. Alitalo, and B. Wasylyk. 2001. Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 20:5139-5152.
-
(2001)
EMBO J
, vol.20
, pp. 5139-5152
-
-
Ayadi, A.1
Zheng, H.2
Sobieszczuk, P.3
Buchwalter, G.4
Moerman, P.5
Alitalo, K.6
Wasylyk, B.7
-
6
-
-
33846333812
-
Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor
-
Bäckhed, F., P.A. Crawford, D. O'Donnell, and J.I. Gordon. 2007. Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor. Proc. Natl. Acad. Sci. USA. 104:606-611.
-
(2007)
Proc. Natl. Acad. Sci. USA.
, vol.104
, pp. 606-611
-
-
Bäckhed, F.1
Crawford, P.A.2
O'Donnell, D.3
Gordon, J.I.4
-
7
-
-
34948814992
-
Functionally specialized junctions between endothelial cells of lymphatic vessels
-
Baluk, P., J. Fuxe, H. Hashizume, T. Romano, E. Lashnits, S. Butz, D. Vestweber, M. Corada, C. Molendini, E. Dejana, and D.M. McDonald. 2007. Functionally specialized junctions between endothelial cells of lymphatic vessels. J. Exp. Med. 204:2349-2362.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2349-2362
-
-
Baluk, P.1
Fuxe, J.2
Hashizume, H.3
Romano, T.4
Lashnits, E.5
Butz, S.6
Vestweber, D.7
Corada, M.8
Molendini, C.9
Dejana, E.10
McDonald, D.M.11
-
8
-
-
68349105030
-
Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis
-
Bazigou, E., S. Xie, C. Chen, A. Weston, N. Miura, L. Sorokin, R. Adams, A.F. Muro, D. Sheppard, and T. Makinen. 2009. Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev. Cell. 17:175-186.
-
(2009)
Dev. Cell.
, vol.17
, pp. 175-186
-
-
Bazigou, E.1
Xie, S.2
Chen, C.3
Weston, A.4
Miura, N.5
Sorokin, L.6
Adams, R.7
Muro, A.F.8
Sheppard, D.9
Makinen, T.10
-
9
-
-
77952885004
-
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling
-
Bertozzi, C.C., A.A. Schmaier, P. Mericko, P.R. Hess, Z. Zou, M. Chen, C.Y. Chen, B. Xu, M.M. Lu, D. Zhou, et al. 2010. Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood. 116:661-670.
-
(2010)
Blood
, vol.116
, pp. 661-670
-
-
Bertozzi, C.C.1
Schmaier, A.A.2
Mericko, P.3
Hess, P.R.4
Zou, Z.5
Chen, M.6
Chen, C.Y.7
Xu, B.8
Lu, M.M.9
Zhou, D.10
-
10
-
-
77950585593
-
Regulation of developmental lymphangiogenesis by Syk(+) leukocytes
-
Böhmer, R., B. Neuhaus, S. Bühren, D. Zhang, M. Stehling, B. Böck, and F. Kiefer. 2010. Regulation of developmental lymphangiogenesis by Syk(+) leukocytes. Dev. Cell. 18:437-449.
-
(2010)
Dev. Cell
, vol.18
, pp. 437-449
-
-
Böhmer, R.1
Neuhaus, B.2
Bühren, S.3
Zhang, D.4
Stehling, M.5
Böck, B.6
Kiefer, F.7
-
11
-
-
18444378418
-
Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24
-
Brice, G., S. Mansour, R. Bell, J.R. Collin, A.H. Child, A.F. Brady, M. Sarfarazi, K.G. Burnand, S. Jeffery, P. Mortimer, and V.A. Murday. 2002. Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24. J. Med. Genet. 39:478-483.
-
(2002)
J. Med. Genet.
, vol.39
, pp. 478-483
-
-
Brice, G.1
Mansour, S.2
Bell, R.3
Collin, J.R.4
Child, A.H.5
Brady, A.F.6
Sarfarazi, M.7
Burnand, K.G.8
Jeffery, S.9
Mortimer, P.10
Murday, V.A.11
-
12
-
-
77955759587
-
Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk
-
Bussmann, J., F.L. Bos, A. Urasaki, K. Kawakami, H.J. Duckers, and S. Schulte-Merker. 2010. Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk. Development. 137:2653-2657.
-
(2010)
Development
, vol.137
, pp. 2653-2657
-
-
Bussmann, J.1
Bos, F.L.2
Urasaki, A.3
Kawakami, K.4
Duckers, H.J.5
Schulte-Merker, S.6
-
13
-
-
77951296956
-
Platelets play an essential role in separating the blood and lymphatic vasculatures during embryonic angiogenesis
-
Carramolino, L., J. Fuentes, C. García-Andrés, V. Azcoitia, D. Riethmacher, and M. Torres. 2010. Platelets play an essential role in separating the blood and lymphatic vasculatures during embryonic angiogenesis. Circ. Res. 106:1197-1201.
-
(2010)
Circ. Res.
, vol.106
, pp. 1197-1201
-
-
Carramolino, L.1
Fuentes, J.2
García-Andrés, C.3
Azcoitia, V.4
Riethmacher, D.5
Torres, M.6
-
14
-
-
0034705207
-
Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis
-
Carsillo, T., A. Astrinidis, and E.P. Henske. 2000. Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis. Proc. Natl. Acad. Sci. USA. 97:6085-6090.
-
(2000)
Proc. Natl. Acad. Sci. USA.
, vol.97
, pp. 6085-6090
-
-
Carsillo, T.1
Astrinidis, A.2
Henske, E.P.3
-
15
-
-
77951833399
-
Tbx1 regulates Vegfr3 and is required for lymphatic vessel development
-
Chen, L., A. Mupo, T. Huynh, S. Cioffi, M. Woods, C. Jin, W. McKeehan, L. Thompson-Snipes, A. Baldini, and E. Illingworth. 2010. Tbx1 regulates Vegfr3 and is required for lymphatic vessel development. J. Cell Biol. 189:417-424.
-
(2010)
J. Cell Biol.
, vol.189
, pp. 417-424
-
-
Chen, L.1
Mupo, A.2
Huynh, T.3
Cioffi, S.4
Woods, M.5
Jin, C.6
McKeehan, W.7
Thompson-Snipes, L.8
Baldini, A.9
Illingworth, E.10
-
16
-
-
33144465966
-
Gorham-Stout syndrome: a monocyte-mediated cytokine propelled disease
-
Colucci, S., G. Taraboletti, L. Primo, A. Viale, C. Roca, D. Valdembri, M. Geuna, M. Pagano, M. Grano, A.M. Pogrel, et al. 2006. Gorham-Stout syndrome: a monocyte-mediated cytokine propelled disease. J. Bone Miner. Res. 21:207-218.
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 207-218
-
-
Colucci, S.1
Taraboletti, G.2
Primo, L.3
Viale, A.4
Roca, C.5
Valdembri, D.6
Geuna, M.7
Pagano, M.8
Grano, M.9
Pogrel, A.M.10
-
17
-
-
4744342993
-
Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome
-
Dagenais, S.L., R.L. Hartsough, R.P. Erickson, M.H. Witte, M.G. Butler, and T.W. Glover. 2004. Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome. Gene Expr. Patterns. 4:611-619.
-
(2004)
Gene Expr. Patterns.
, vol.4
, pp. 611-619
-
-
Dagenais, S.L.1
Hartsough, R.L.2
Erickson, R.P.3
Witte, M.H.4
Butler, M.G.5
Glover, T.W.6
-
18
-
-
70450193250
-
Regulation of lymphatic-blood vessel separation by endothelial Rac1
-
D'Amico, G., D.T. Jones, E. Nye, K. Sapienza, A.R. Ramjuan, L.E. Reynolds, S.D. Robinson, V. Kostourou, D. Martinez, D. Aubyn, et al. 2009. Regulation of lymphatic-blood vessel separation by endothelial Rac1. Development. 136:4043-4053.
-
(2009)
Development
, vol.136
, pp. 4043-4053
-
-
D'Amico, G.1
Jones, D.T.2
Nye, E.3
Sapienza, K.4
Ramjuan, A.R.5
Reynolds, L.E.6
Robinson, S.D.7
Kostourou, V.8
Martinez, D.9
Aubyn, D.10
-
19
-
-
75149155724
-
Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report
-
D'Amico, G., E.A. Korhonen, M. Waltari, P. Saharinen, P. Laakkonen, and K. Alitalo. 2010. Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report. Arterioscler. Thromb. Vasc. Biol. 30:207-209.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 207209
-
-
D'Amico, G.1
Korhonen, E.A.2
Waltari, M.3
Saharinen, P.4
Laakkonen, P.5
Alitalo, K.6
-
20
-
-
44949239610
-
Emilin1 deficiency causes structural and functional defects of lymphatic vasculature
-
Danussi, C., P. Spessotto, A. Petrucco, B. Wassermann, P. Sabatelli, M. Montesi, R. Doliana, G.M. Bressan, and A. Colombatti. 2008. Emilin1 deficiency causes structural and functional defects of lymphatic vasculature. Mol. Cell. Biol. 28:4026-4039.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4026-4039
-
-
Danussi, C.1
Spessotto, P.2
Petrucco, A.3
Wassermann, B.4
Sabatelli, P.5
Montesi, M.6
Doliana, R.7
Bressan, G.M.8
Colombatti, A.9
-
21
-
-
57749192473
-
Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees
-
Dejana, E., F. Orsenigo, C. Molendini, P. Baluk, and D.M. McDonald. 2009. Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees. Cell Tissue Res. 335:17-25.
-
(2009)
Cell Tissue Res
, vol.335
, pp. 17-25
-
-
Dejana, E.1
Orsenigo, F.2
Molendini, C.3
Baluk, P.4
McDonald, D.M.5
-
22
-
-
46049111407
-
Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice
-
Dellinger, M., R. Hunter, M. Bernas, N. Gale, G. Yancopoulos, R. Erickson, and M. Witte. 2008. Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice. Dev. Biol. 319:309-320.
-
(2008)
Dev. Biol.
, vol.319
, pp. 309-320
-
-
Dellinger, M.1
Hunter, R.2
Bernas, M.3
Gale, N.4
Yancopoulos, G.5
Erickson, R.6
Witte, M.7
-
23
-
-
0033646615
-
Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome
-
Fang, J., S.L. Dagenais, R.P. Erickson, M.F. Arlt, M.W. Glynn, J.L. Gorski, L.H. Seaver, and T.W. Glover. 2000. Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome. Am. J. Hum. Genet. 67:1382-1388.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 1382-1388
-
-
Fang, J.1
Dagenais, S.L.2
Erickson, R.P.3
Arlt, M.F.4
Glynn, M.W.5
Gorski, J.L.6
Seaver, L.H.7
Glover, T.W.8
-
24
-
-
77953120512
-
GJC2 missense mutations cause human lymphedema
-
Ferrell, R.E., C.J. Baty, M.A. Kimak, J.M. Karlsson, E.C. Lawrence, M. Franke-Snyder, S.D. Meriney, E. Feingold, and D.N. Finegold. 2010. GJC2 missense mutations cause human lymphedema. Am. J. Hum. Genet. 86:943-948.
-
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 943-948
-
-
Ferrell, R.E.1
Baty, C.J.2
Kimak, M.A.3
Karlsson, J.M.4
Lawrence, E.C.5
Franke-Snyder, M.6
Meriney, S.D.7
Feingold, E.8
Finegold, D.N.9
-
25
-
-
33747242116
-
-
Second edition. Urban and Fischer, Munich
-
Földi, M., E. Földi, R.H.K. Strößenreuther, and S. Kubic, editors. 2006. Földi's Textbook of Lymphology: For Physicians and Lymphedema Therapists. Second edition. Urban and Fischer, Munich. 736 pp..
-
(2006)
Földi's Textbook of Lymphology: For Physicians and Lymphedema Therapists
, pp. 736
-
-
Földi, M.1
Földi, E.2
Strößenreuther, R.H.K.3
Kubic, S.4
-
26
-
-
57349142376
-
Sox18 induces development of the lymphatic vasculature in mice
-
François, M., A. Caprini, B. Hosking, F. Orsenigo, D. Wilhelm, C. Browne, K. Paavonen, T. Karnezis, R. Shayan, M. Downes, et al. 2008. Sox18 induces development of the lymphatic vasculature in mice. Nature. 456:643-647.
-
(2008)
Nature
, vol.456
, pp. 643-647
-
-
François, M.1
Caprini, A.2
Hosking, B.3
Orsenigo, F.4
Wilhelm, D.5
Browne, C.6
Paavonen, K.7
Karnezis, T.8
Shayan, R.9
Downes, M.10
-
27
-
-
38149064606
-
Adrenomedullin signaling is necessary for murine lymphatic vascular development
-
Fritz-Six, K.L., W.P. Dunworth, M. Li, and K.M. Caron. 2008. Adrenomedullin signaling is necessary for murine lymphatic vascular development. J. Clin. Invest. 118:40-50.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 40-50
-
-
Fritz-Six, K.L.1
Dunworth, W.P.2
Li, M.3
Caron, K.M.4
-
28
-
-
55849149808
-
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice
-
Fu, J., H. Gerhardt, J.M. McDaniel, B. Xia, X. Liu, L. Ivanciu, A. Ny, K. Hermans, R. Silasi-Mansat, S. McGee, et al. 2008. Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice. J. Clin. Invest. 118:3725-3737.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3725-3737
-
-
Fu, J.1
Gerhardt, H.2
McDaniel, J.M.3
Xia, B.4
Liu, X.5
Ivanciu, L.6
Ny, A.7
Hermans, K.8
Silasi-Mansat, R.9
McGee, S.10
-
29
-
-
18644382318
-
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1
-
Gale, N.W., G. Thurston, S.F. Hackett, R. Renard, Q. Wang, J. McClain, C. Martin, C. Witte, M.H. Witte, D. Jackson, et al. 2002. Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. Dev. Cell. 3:411-423.
-
(2002)
Dev. Cell
, vol.3
, pp. 411-423
-
-
Gale, N.W.1
Thurston, G.2
Hackett, S.F.3
Renard, R.4
Wang, Q.5
McClain, J.6
Martin, C.7
Witte, C.8
Witte, M.H.9
Jackson, D.10
-
30
-
-
77955982948
-
Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish
-
Geudens, I., R. Herpers, K. Hermans, I. Segura, C. Ruiz de Almodovar, J. Bussmann, F. De Smet, W. Vandevelde, B.M. Hogan, A. Siekmann, et al. 2010. Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler. Thromb. Vasc. Biol. 30:1695- 1702.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1695-1702
-
-
Geudens, I.1
Herpers, R.2
Hermans, K.3
Segura, I.4
Ruiz de Almodovar, C.5
Bussmann, J.6
De Smet, F.7
Vandevelde, W.8
Hogan, B.M.9
Siekmann, A.10
-
31
-
-
78650919021
-
Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity
-
Gjini, E., L.H. Hekking, A. Küchler, P. Saharinen, E. Wienholds, J.A. Post, K. Alitalo, and S. Schulte-Merker. 2011. Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity. Dis Model Mech. 4:57-66.
-
(2011)
Dis Model Mech
, vol.4
, pp. 57-66
-
-
Gjini, E.1
Hekking, L.H.2
Küchler, A.3
Saharinen, P.4
Wienholds, E.5
Post, J.A.6
Alitalo, K.7
Schulte-Merker, S.8
-
32
-
-
77953005726
-
Lymphangioleiomyomatosis (LAM): molecular insights lead to targeted therapies
-
Glasgow, C.G., W.K. Steagall, A. Taveira-Dasilva, G. Pacheco-Rodriguez, X. Cai, S. El-Chemaly, M. Moses, T. Darling, and J. Moss. 2010. Lymphangioleiomyomatosis (LAM): molecular insights lead to targeted therapies. Respir. Med. 104(Suppl. 1):S45-S58.
-
(2010)
Respir. Med.
, vol.104
, Issue.SUPPL. 1
-
-
Glasgow, C.G.1
Steagall, W.K.2
Taveira-Dasilva, A.3
Pacheco-Rodriguez, G.4
Cai, X.5
El-Chemaly, S.6
Moses, M.7
Darling, T.8
Moss, J.9
-
33
-
-
78149246290
-
Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation
-
Gordon, E.J., S. Rao, J.W. Pollard, S.L. Nutt, R.A. Lang, and N.L. Harvey. 2010. Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 137:3899-3910.
-
(2010)
Development
, vol.137
, pp. 3899-3910
-
-
Gordon, E.J.1
Rao, S.2
Pollard, J.W.3
Nutt, S.L.4
Lang, R.A.5
Harvey, N.L.6
-
34
-
-
34249026448
-
Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice
-
Gupta, S., A.R. Ramjaun, P. Haiko, Y. Wang, P.H. Warne, B. Nicke, E. Nye, G. Stamp, K. Alitalo, and J. Downward. 2007. Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice. Cell. 129:957-968.
-
(2007)
Cell
, vol.129
, pp. 957-968
-
-
Gupta, S.1
Ramjaun, A.R.2
Haiko, P.3
Wang, Y.4
Warne, P.H.5
Nicke, B.6
Nye, E.7
Stamp, G.8
Alitalo, K.9
Downward, J.10
-
35
-
-
33751572021
-
Platelet-derived growth factor receptor-beta in Gorham's disease
-
Hagendoorn, J., T.P. Padera, T.I. Yock, G.P. Nielsen, E. di Tomaso, D.G. Duda, T.F. Delaney, H.A. Gaissert, J. Pearce, A.E. Rosenberg, et al. 2006. Platelet-derived growth factor receptor-beta in Gorham's disease. Nat. Clin. Pract. Oncol. 3:693-697.
-
(2006)
Nat. Clin. Pract. Oncol.
, vol.3
, pp. 693-697
-
-
Hagendoorn, J.1
Padera, T.P.2
Yock, T.I.3
Nielsen, G.P.4
di Tomaso, E.5
Duda, D.G.6
Delaney, T.F.7
Gaissert, H.A.8
Pearce, J.9
Rosenberg, A.E.10
-
36
-
-
47949083776
-
Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos
-
Haiko, P., T. Makinen, S. Keskitalo, J. Taipale, M.J. Karkkainen, M.E. Baldwin, S.A. Stacker, M.G. Achen, and K. Alitalo. 2008. Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos. Mol. Cell. Biol. 28:4843- 4850.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4843-4850
-
-
Haiko, P.1
Makinen, T.2
Keskitalo, S.3
Taipale, J.4
Karkkainen, M.J.5
Baldwin, M.E.6
Stacker, S.A.7
Achen, M.G.8
Alitalo, K.9
-
37
-
-
75149196431
-
KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming
-
Hansen, A., S. Henderson, D. Lagos, L. Nikitenko, E. Coulter, S. Roberts, F. Gratrix, K. Plaisance, R. Renne, M. Bower, et al. 2010. KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. Genes Dev. 24:195-205.
-
(2010)
Genes Dev
, vol.24
, pp. 195-205
-
-
Hansen, A.1
Henderson, S.2
Lagos, D.3
Nikitenko, L.4
Coulter, E.5
Roberts, S.6
Gratrix, F.7
Plaisance, K.8
Renne, R.9
Bower, M.10
-
38
-
-
27144478129
-
Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity
-
Harvey, N.L., R.S. Srinivasan, M.E. Dillard, N.C. Johnson, M.H. Witte, K. Boyd, M.W. Sleeman, and G. Oliver. 2005. Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nat. Genet. 37:1072-1081.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1072-1081
-
-
Harvey, N.L.1
Srinivasan, R.S.2
Dillard, M.E.3
Johnson, N.C.4
Witte, M.H.5
Boyd, K.6
Sleeman, M.W.7
Oliver, G.8
-
39
-
-
78049372104
-
Role of synectin in lymphatic development in zebrafish and frogs
-
Hermans, K., F. Claes, W. Vandevelde, W. Zheng, I. Geudens, F. Orsenigo, F. De Smet, E. Gjini, K. Anthonis, B. Ren, et al. 2010. Role of synectin in lymphatic development in zebrafish and frogs. Blood. 116:3356-3366.
-
(2010)
Blood
, vol.116
, pp. 3356-3366
-
-
Hermans, K.1
Claes, F.2
Vandevelde, W.3
Zheng, W.4
Geudens, I.5
Orsenigo, F.6
De Smet, F.7
Gjini, E.8
Anthonis, K.9
Ren, B.10
-
40
-
-
40949156610
-
Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos
-
Hirashima, M., K. Sano, T. Morisada, K. Murakami, J. Rossant, and T. Suda. 2008. Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev. Biol. 316:149-159.
-
(2008)
Dev. Biol.
, vol.316
, pp. 149-159
-
-
Hirashima, M.1
Sano, K.2
Morisada, T.3
Murakami, K.4
Rossant, J.5
Suda, T.6
-
41
-
-
0035660157
-
Cellular and humoral mechanisms of osteoclast formation and bone resorption in Gorham-Stout disease
-
Hirayama, T., A. Sabokbar, I. Itonaga, S. Watt-Smith, and N.A. Athanasou. 2001. Cellular and humoral mechanisms of osteoclast formation and bone resorption in Gorham-Stout disease. J. Pathol. 195:624-630.
-
(2001)
J. Pathol.
, vol.195
, pp. 624-630
-
-
Hirayama, T.1
Sabokbar, A.2
Itonaga, I.3
Watt-Smith, S.4
Athanasou, N.A.5
-
42
-
-
63449128207
-
Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting
-
Hogan, B.M., F.L. Bos, J. Bussmann, M. Witte, N.C. Chi, H.J. Duckers, and S. Schulte-Merker. 2009a. Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nat. Genet. 41:396-398.
-
(2009)
Nat. Genet.
, vol.41
, pp. 396-398
-
-
Hogan, B.M.1
Bos, F.L.2
Bussmann, J.3
Witte, M.4
Chi, N.C.5
Duckers, H.J.6
Schulte-Merker, S.7
-
43
-
-
70450195982
-
Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries
-
Hogan, B.M., R. Herpers, M. Witte, H. Heloterä, K. Alitalo, H.J. Duckers, and S. Schulte-Merker. 2009b. Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries. Development. 136:4001-4009.
-
(2009)
Development
, vol.136
, pp. 4001-4009
-
-
Hogan, B.M.1
Herpers, R.2
Witte, M.3
Heloterä, H.4
Alitalo, K.5
Duckers, H.J.6
Schulte-Merker, S.7
-
44
-
-
0036840138
-
Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate
-
Hong, Y.K., N. Harvey, Y.H. Noh, V. Schacht, S. Hirakawa, M. Detmar, and G. Oliver. 2002. Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev. Dyn. 225:351-357.
-
(2002)
Dev. Dyn.
, vol.225
, pp. 351-357
-
-
Hong, Y.K.1
Harvey, N.2
Noh, Y.H.3
Schacht, V.4
Hirakawa, S.5
Detmar, M.6
Oliver, G.7
-
45
-
-
3042780203
-
Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus
-
Hong, Y.K., K. Foreman, J.W. Shin, S. Hirakawa, C.L. Curry, D.R. Sage, T. Libermann, B.J. Dezube, J.D. Fingeroth, and M. Detmar. 2004. Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus. Nat. Genet. 36:683-685.
-
(2004)
Nat. Genet.
, vol.36
, pp. 683-685
-
-
Hong, Y.K.1
Foreman, K.2
Shin, J.W.3
Hirakawa, S.4
Curry, C.L.5
Sage, D.R.6
Libermann, T.7
Dezube, B.J.8
Fingeroth, J.D.9
Detmar, M.10
-
46
-
-
62349108155
-
Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice
-
Ichise, H., T. Ichise, O. Ohtani, and N. Yoshida. 2009. Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice. Development. 136:191-195.
-
(2009)
Development
, vol.136
, pp. 191-195
-
-
Ichise, H.1
Ichise, T.2
Ohtani, O.3
Yoshida, N.4
-
47
-
-
0038353732
-
Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia
-
Irrthum, A., K. Devriendt, D. Chitayat, G. Matthijs, C. Glade, P.M. Steijlen, J.P. Fryns, M.A. Van Steensel, and M. Vikkula. 2003. Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. Am. J. Hum. Genet. 72:1470-1478.
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 1470-1478
-
-
Irrthum, A.1
Devriendt, K.2
Chitayat, D.3
Matthijs, G.4
Glade, C.5
Steijlen, P.M.6
Fryns, J.P.7
Van Steensel, M.A.8
Vikkula, M.9
-
48
-
-
57749087100
-
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity
-
Johnson, N.C., M.E. Dillard, P. Baluk, D.M. McDonald, N.L. Harvey, S.L. Frase, and G. Oliver. 2008. Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity. Genes Dev. 22:3282-3291.
-
(2008)
Genes Dev
, vol.22
, pp. 3282-3291
-
-
Johnson, N.C.1
Dillard, M.E.2
Baluk, P.3
McDonald, D.M.4
Harvey, N.L.5
Frase, S.L.6
Oliver, G.7
-
49
-
-
0028938746
-
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
-
Kaipainen, A., J. Korhonen, T. Mustonen, V.W. van Hinsbergh, G.-H. Fang, D. Dumont, M. Breitman, and K. Alitalo. 1995. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc. Natl. Acad. Sci. USA. 92:3566-3570.
-
(1995)
Proc. Natl. Acad. Sci. USA.
, vol.92
, pp. 3566-3570
-
-
Kaipainen, A.1
Korhonen, J.2
Mustonen, T.3
van Hinsbergh, V.W.4
Fang, G.-H.5
Dumont, D.6
Breitman, M.7
Alitalo, K.8
-
51
-
-
0034041161
-
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
-
Karkkainen, M.J., R.E. Ferrell, E.C. Lawrence, M.A. Kimak, K.L. Levinson, M.A. McTigue, K. Alitalo, and D.N. Finegold. 2000. Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema. Nat. Genet. 25:153-159.
-
(2000)
Nat. Genet.
, vol.25
, pp. 153-159
-
-
Karkkainen, M.J.1
Ferrell, R.E.2
Lawrence, E.C.3
Kimak, M.A.4
Levinson, K.L.5
McTigue, M.A.6
Alitalo, K.7
Finegold, D.N.8
-
52
-
-
0035940403
-
A model for gene therapy of human hereditary lymphedema
-
Karkkainen, M.J., A. Saaristo, L. Jussila, K.A. Karila, E.C. Lawrence, K. Pajusola, H. Bueler, A. Eichmann, R. Kauppinen, M.I. Kettunen, et al. 2001. A model for gene therapy of human hereditary lymphedema. Proc. Natl. Acad. Sci. USA. 98:12677-12682.
-
(2001)
Proc. Natl. Acad. Sci. USA.
, vol.98
, pp. 12677-12682
-
-
Karkkainen, M.J.1
Saaristo, A.2
Jussila, L.3
Karila, K.A.4
Lawrence, E.C.5
Pajusola, K.6
Bueler, H.7
Eichmann, A.8
Kauppinen, R.9
Kettunen, M.I.10
-
53
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
Karkkainen, M.J., P. Haiko, K. Sainio, J. Partanen, J. Taipale, T.V. Petrova, M. Jeltsch, D.G. Jackson, M. Talikka, H. Rauvala, et al. 2003. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat. Immunol. 5:74-80.
-
(2003)
Nat. Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
Partanen, J.4
Taipale, J.5
Petrova, T.V.6
Jeltsch, M.7
Jackson, D.G.8
Talikka, M.9
Rauvala, H.10
-
54
-
-
33746503288
-
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
-
Kärpänen, T., C.A. Heckman, S. Keskitalo, M. Jeltsch, H. Ollila, G. Neufeld, L. Tamagnone, and K. Alitalo. 2006a. Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J. 20:1462-1472.
-
(2006)
FASEB J
, vol.20
, pp. 1462-1472
-
-
Kärpänen, T.1
Heckman, C.A.2
Keskitalo, S.3
Jeltsch, M.4
Ollila, H.5
Neufeld, G.6
Tamagnone, L.7
Alitalo, K.8
-
55
-
-
33746633329
-
Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation
-
Kärpänen, T., M. Wirzenius, T. Mäkinen, T. Veikkola, H.J. Haisma, M.G. Achen, S.A. Stacker, B. Pytowski, S. Ylä-Herttuala, and K. Alitalo. 2006b. Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation. Am. J. Pathol. 169:708-718.
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 708-718
-
-
Kärpänen, T.1
Wirzenius, M.2
Mäkinen, T.3
Veikkola, T.4
Haisma, H.J.5
Achen, M.G.6
Stacker, S.A.7
Pytowski, B.8
Ylä-Herttuala, S.9
Alitalo, K.10
-
56
-
-
33744996035
-
Development of the zebrafish lymphatic system requires VEGFC signaling
-
Küchler, A.M., E. Gjini, J. Peterson-Maduro, B. Cancilla, H. Wolburg, and S. Schulte-Merker. 2006. Development of the zebrafish lymphatic system requires VEGFC signaling. Curr. Biol. 16:1244-1248.
-
(2006)
Curr. Biol.
, vol.16
, pp. 1244-1248
-
-
Küchler, A.M.1
Gjini, E.2
Peterson-Maduro, J.3
Cancilla, B.4
Wolburg, H.5
Schulte-Merker, S.6
-
57
-
-
20444502607
-
Dosage-dependent requirement for mouse Vezf1 in vascular system development
-
Kuhnert, F., L. Campagnolo, J.W. Xiong, D. Lemons, M.J. Fitch, Z. Zou, W.B. Kiosses, H. Gardner, and H. Stuhlmann. 2005. Dosage-dependent requirement for mouse Vezf1 in vascular system development. Dev. Biol. 283:140-156.
-
(2005)
Dev. Biol.
, vol.283
, pp. 140-156
-
-
Kuhnert, F.1
Campagnolo, L.2
Xiong, J.W.3
Lemons, D.4
Fitch, M.J.5
Zou, Z.6
Kiosses, W.B.7
Gardner, H.8
Stuhlmann, H.9
-
58
-
-
0015868809
-
The ultrastructure of lymphatic valves in the adult rabbit lung
-
Lauweryns, J.M., and L. Boussauw. 1973. The ultrastructure of lymphatic valves in the adult rabbit lung. Z. Zellforsch. Mikrosk. Anat. 143:149-168.
-
(1973)
Z. Zellforsch. Mikrosk. Anat.
, vol.143
, pp. 149-168
-
-
Lauweryns, J.M.1
Boussauw, L.2
-
59
-
-
0000415005
-
Ultrastructural studies on the lymphatic anchoring filaments
-
Leak, L.V., and J.F. Burke. 1968. Ultrastructural studies on the lymphatic anchoring filaments. J. Cell Biol. 36:129-149.
-
(1968)
J. Cell Biol.
, vol.36
, pp. 129-149
-
-
Leak, L.V.1
Burke, J.F.2
-
60
-
-
61849097153
-
Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate
-
Lee, S., J. Kang, J. Yoo, S.K. Ganesan, S.C. Cook, B. Aguilar, S. Ramu, J. Lee, and Y.K. Hong. 2009. Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate. Blood. 113:1856- 1859.
-
(2009)
Blood
, vol.113
, pp. 1856-1859
-
-
Lee, S.1
Kang, J.2
Yoo, J.3
Ganesan, S.K.4
Cook, S.C.5
Aguilar, B.6
Ramu, S.7
Lee, J.8
Hong, Y.K.9
-
62
-
-
78649499036
-
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages
-
Lichtenstein, L., F. Mattijssen, N.J. de Wit, A. Georgiadi, G.J. Hooiveld, R. van der Meer, Y. He, L. Qi, A. Köster, J.T. Tamsma, et al. 2010. Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages. Cell Metab. 12:580-592.
-
(2010)
Cell Metab
, vol.12
, pp. 580-592
-
-
Lichtenstein, L.1
Mattijssen, F.2
de Wit, N.J.3
Georgiadi, A.4
Hooiveld, G.J.5
van der Meer, R.6
He, Y.7
Qi, L.8
Köster, A.9
Tamsma, J.T.10
-
63
-
-
77951847278
-
Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development
-
Lin, F.J., X. Chen, J. Qin, Y.K. Hong, M.J. Tsai, and S.Y. Tsai. 2010. Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J. Clin. Invest. 120:1694- 1707.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1694-1707
-
-
Lin, F.J.1
Chen, X.2
Qin, J.3
Hong, Y.K.4
Tsai, M.J.5
Tsai, S.Y.6
-
64
-
-
0035122695
-
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
-
Mäkinen, T., L. Jussila, T. Veikkola, T. Kärpänen, M.I. Kettunen, K.J. Pulkkanen, R. Kauppinen, D.G. Jackson, H. Kubo, S.-I. Nishikawa, et al. 2001. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat. Med. 7:199-205.
-
(2001)
Nat. Med.
, vol.7
, pp. 199-205
-
-
Mäkinen, T.1
Jussila, L.2
Veikkola, T.3
Kärpänen, T.4
Kettunen, M.I.5
Pulkkanen, K.J.6
Kauppinen, R.7
Jackson, D.G.8
Kubo, H.9
Nishikawa, S.-I.10
-
65
-
-
13244292521
-
PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature
-
Mäkinen, T., R.H. Adams, J. Bailey, Q. Lu, A. Ziemiecki, K. Alitalo, R. Klein, and G.A. Wilkinson. 2005. PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev. 19:397-410.
-
(2005)
Genes Dev
, vol.19
, pp. 397-410
-
-
Mäkinen, T.1
Adams, R.H.2
Bailey, J.3
Lu, Q.4
Ziemiecki, A.5
Alitalo, K.6
Klein, R.7
Wilkinson, G.A.8
-
66
-
-
34247168398
-
Lymphoedema Research Consortium Mutations in FOXC2 are strongly associated with primary valve failure in veins of the lower limb
-
Mellor, R.H., G. Brice, A.W. Stanton, J. French, A. Smith, S. Jeffery, J.R. Levick, K.G. Burnand, and P.S. Mortimer Lymphoedema Research Consortium. 2007. Mutations in FOXC2 are strongly associated with primary valve failure in veins of the lower limb. Circulation. 115:1912-1920.
-
(2007)
Circulation
, vol.115
, pp. 1912-1920
-
-
Mellor, R.H.1
Brice, G.2
Stanton, A.W.3
French, J.4
Smith, A.5
Jeffery, S.6
Levick, J.R.7
Burnand, K.G.8
Mortimer, P.S.9
-
67
-
-
77951695913
-
Lymphatic dysfunction, not aplasia, underlies Milroy disease
-
Mellor, R.H., C.E. Hubert, A.W. Stanton, N. Tate, V. Akhras, A. Smith, K.G. Burnand, S. Jeffery, T. Mäkinen, J.R. Levick, and P.S. Mortimer. 2010. Lymphatic dysfunction, not aplasia, underlies Milroy disease. Microcirculation. 17:281-296.
-
(2010)
Microcirculation
, vol.17
, pp. 281-296
-
-
Mellor, R.H.1
Hubert, C.E.2
Stanton, A.W.3
Tate, N.4
Akhras, V.5
Smith, A.6
Burnand, K.G.7
Jeffery, S.8
Mäkinen, T.9
Levick, J.R.10
Mortimer, P.S.11
-
68
-
-
77957121811
-
Kaposi's sarcoma and its associated herpesvirus
-
Mesri, E.A., E. Cesarman, and C. Boshoff. 2010. Kaposi's sarcoma and its associated herpesvirus. Nat. Rev. Cancer. 10:707-719.
-
(2010)
Nat. Rev. Cancer.
, vol.10
, pp. 707-719
-
-
Mesri, E.A.1
Cesarman, E.2
Boshoff, C.3
-
69
-
-
77950899035
-
Transmural flow modulates cell and fluid transport functions of lymphatic endothelium
-
Miteva, D.O., J.M. Rutkowski, J.B. Dixon, W. Kilarski, J.D. Shields, and M.A. Swartz. 2010. Transmural flow modulates cell and fluid transport functions of lymphatic endothelium. Circ. Res. 106:920-931.
-
(2010)
Circ. Res.
, vol.106
, pp. 920-931
-
-
Miteva, D.O.1
Rutkowski, J.M.2
Dixon, J.B.3
Kilarski, W.4
Shields, J.D.5
Swartz, M.A.6
-
70
-
-
70349306570
-
Organspecific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha
-
Mouta-Bellum, C., A. Kirov, L. Miceli-Libby, M.L. Mancini, T.V. Petrova, L. Liaw, I. Prudovsky, P.E. Thorpe, N. Miura, L.C. Cantley, et al. 2009. Organspecific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Dev. Dyn. 238:2670-2679.
-
(2009)
Dev. Dyn.
, vol.238
, pp. 2670-2679
-
-
Mouta-Bellum, C.1
Kirov, A.2
Miceli-Libby, L.3
Mancini, M.L.4
Petrova, T.V.5
Liaw, L.6
Prudovsky, I.7
Thorpe, P.E.8
Miura, N.9
Cantley, L.C.10
-
71
-
-
0038661156
-
Molecular and functional analyses of the contractile apparatus in lymphatic muscle
-
Muthuchamy, M., A. Gashev, N. Boswell, N. Dawson, and D. Zawieja. 2003. Molecular and functional analyses of the contractile apparatus in lymphatic muscle. FASEB J. 17:920-922.
-
(2003)
FASEB J
, vol.17
, pp. 920-922
-
-
Muthuchamy, M.1
Gashev, A.2
Boswell, N.3
Dawson, N.4
Zawieja, D.5
-
72
-
-
77951498501
-
VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts
-
Nilsson, I., F. Bahram, X. Li, L. Gualandi, S. Koch, M. Jarvius, O. Söderberg, A. Anisimov, I. Kholová, B. Pytowski, et al. 2010. VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts. EMBO J. 29:1377-1388.
-
(2010)
EMBO J
, vol.29
, pp. 1377-1388
-
-
Nilsson, I.1
Bahram, F.2
Li, X.3
Gualandi, L.4
Koch, S.5
Jarvius, M.6
Söderberg, O.7
Anisimov, A.8
Kholová, I.9
Pytowski, B.10
-
73
-
-
65649096621
-
FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1
-
Norrmén, C., K.I. Ivanov, J. Cheng, N. Zangger, M. Delorenzi, M. Jaquet, N. Miura, P. Puolakkainen, V. Horsley, J. Hu, et al. 2009. FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J. Cell Biol. 185:439-457.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 439-457
-
-
Norrmén, C.1
Ivanov, K.I.2
Cheng, J.3
Zangger, N.4
Delorenzi, M.5
Jaquet, M.6
Miura, N.7
Puolakkainen, P.8
Horsley, V.9
Hu, J.10
-
74
-
-
24744449289
-
A genetic Xenopus laevis tadpole model to study lymphangiogenesis
-
Ny, A., M. Koch, M. Schneider, E. Neven, R.T. Tong, S. Maity, C. Fischer, S. Plaisance, D. Lambrechts, C. Héligon, et al. 2005. A genetic Xenopus laevis tadpole model to study lymphangiogenesis. Nat. Med. 11:998-1004.
-
(2005)
Nat. Med.
, vol.11
, pp. 998-1004
-
-
Ny, A.1
Koch, M.2
Schneider, M.3
Neven, E.4
Tong, R.T.5
Maity, S.6
Fischer, C.7
Plaisance, S.8
Lambrechts, D.9
Héligon, C.10
-
75
-
-
63149180675
-
Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene
-
Pacheco-Rodriguez, G., F. Kumaki, W.K. Steagall, Y. Zhang, Y. Ikeda, J.P. Lin, E.M. Billings, and J. Moss. 2009. Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. J. Immunol. 182:1270-1277.
-
(2009)
J. Immunol.
, vol.182
, pp. 1270-1277
-
-
Pacheco-Rodriguez, G.1
Kumaki, F.2
Steagall, W.K.3
Zhang, Y.4
Ikeda, Y.5
Lin, J.P.6
Billings, E.M.7
Moss, J.8
-
76
-
-
0034461084
-
Mice null for sox18 are viable and display a mild coat defect
-
Pennisi, D., J. Bowles, A. Nagy, G. Muscat, and P. Koopman. 2000. Mice null for sox18 are viable and display a mild coat defect. Mol. Cell. Biol. 20:9331-9336.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9331-9336
-
-
Pennisi, D.1
Bowles, J.2
Nagy, A.3
Muscat, G.4
Koopman, P.5
-
77
-
-
18544386859
-
Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor
-
Petrova, T.V., T. Mäkinen, T.P. Mäkelä, J. Saarela, I. Virtanen, R.E. Ferrell, D.N. Finegold, D. Kerjaschki, S. Ylä-Herttuala, and K. Alitalo. 2002. Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J. 21:4593-4599.
-
(2002)
EMBO J
, vol.21
, pp. 4593-4599
-
-
Petrova, T.V.1
Mäkinen, T.2
Mäkelä, T.P.3
Saarela, J.4
Virtanen, I.5
Ferrell, R.E.6
Finegold, D.N.7
Kerjaschki, D.8
Ylä-Herttuala, S.9
Alitalo, K.10
-
78
-
-
4644362609
-
Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis
-
Petrova, T.V., T. Kärpänen, C. Norrmén, R. Mellor, T. Tamakoshi, D. Finegold, R. Ferrell, D. Kerjaschki, P. Mortimer, S. Ylä-Herttuala, et al. 2004. Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis. Nat. Med. 10:974-981.
-
(2004)
Nat. Med.
, vol.10
, pp. 974-981
-
-
Petrova, T.V.1
Kärpänen, T.2
Norrmén, C.3
Mellor, R.4
Tamakoshi, T.5
Finegold, D.6
Ferrell, R.7
Kerjaschki, D.8
Mortimer, P.9
Ylä-Herttuala, S.10
-
79
-
-
73949156419
-
Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels
-
Pflicke, H., and M. Sixt. 2009. Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels. J. Exp. Med. 206:2925-2935.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2925-2935
-
-
Pflicke H. M., Sixt.1
-
80
-
-
44449173474
-
Gorham's disease: an osseous disease of lymphangiogenesis? Ann
-
Radhakrishnan, K., and S.G. Rockson. 2008. Gorham's disease: an osseous disease of lymphangiogenesis? Ann. NY Acad. Sci. 1131:203-205.
-
(2008)
NY Acad. Sci.
, vol.1131
, pp. 203-205
-
-
Radhakrishnan, K.1
Rockson, S.G.2
-
81
-
-
0035122850
-
Lymphedema
-
Rockson, S.G. 2001. Lymphedema. Am. J. Med. 110:288-295.
-
(2001)
Am. J. Med.
, vol.110
, pp. 288-295
-
-
Rockson, S.G.1
-
82
-
-
45749109360
-
Secondary lymphedema: is it a primary disease?
-
Rockson, S.G. 2008. Secondary lymphedema: is it a primary disease? Lymphat. Res. Biol. 6:63-64.
-
(2008)
Lymphat Res. Biol.
, vol.6
, pp. 63-64
-
-
Rockson, S.G.1
-
83
-
-
84981813798
-
On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig
-
Sabin, F.R. 1902. On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig. Am. J. Anat. 1:367-391.
-
(1902)
Am. J. Anat.
, vol.1
, pp. 367-391
-
-
Sabin, F.R.1
-
84
-
-
77951821586
-
Claudinlike protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development
-
Saharinen, P., H. Helotera, J. Miettinen, C. Norrmen, G. D'Amico, M. Jeltsch, T. Langenberg, W. Vandevelde, A. Ny, M. Dewerchin, et al. 2010. Claudinlike protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 24:875-880.
-
(2010)
Genes Dev
, vol.24
, pp. 875-880
-
-
Saharinen, P.1
Helotera, H.2
Miettinen, J.3
Norrmen, C.4
D'Amico, G.5
Jeltsch, M.6
Langenberg, T.7
Vandevelde, W.8
Ny, A.9
Dewerchin, M.10
-
85
-
-
0036160714
-
Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis
-
Sato, T., K. Seyama, H. Fujii, H. Maruyama, Y. Setoguchi, S. Iwakami, Y. Fukuchi, and O. Hino. 2002. Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis. J. Hum. Genet. 47:20-28.
-
(2002)
J. Hum. Genet.
, vol.47
, pp. 20-28
-
-
Sato, T.1
Seyama, K.2
Fujii, H.3
Maruyama, H.4
Setoguchi, Y.5
Iwakami, S.6
Fukuchi, Y.7
Hino, O.8
-
86
-
-
0041312675
-
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema
-
Schacht, V., M.I. Ramirez, Y.K. Hong, S. Hirakawa, D. Feng, N. Harvey, M. Williams, A.M. Dvorak, H.F. Dvorak, G. Oliver, and M. Detmar. 2003. T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J. 22:3546-3556.
-
(2003)
EMBO J
, vol.22
, pp. 3546-3556
-
-
Schacht, V.1
Ramirez, M.I.2
Hong, Y.K.3
Hirakawa, S.4
Feng, D.5
Harvey, N.6
Williams, M.7
Dvorak, A.M.8
Dvorak, H.F.9
Oliver, G.10
Detmar, M.11
-
87
-
-
77949864294
-
Lymphan gioleiomyomatosis: a disease involving the lymphatic system
-
Seyama, K., T. Kumasaka, M. Kurihara, K. Mitani, and T. Sato. 2010. Lymphan gioleiomyomatosis: a disease involving the lymphatic system. Lymphat. Res. Biol. 8:21-31.
-
(2010)
Lymphat. Res. Biol.
, vol.8
, pp. 21-31
-
-
Seyama, K.1
Kumasaka, T.2
Kurihara, M.3
Mitani, K.4
Sato, T.5
-
89
-
-
34948856826
-
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
-
Srinivasan, R.S., M.E. Dillard, O.V. Lagutin, F.J. Lin, S. Tsai, M.J. Tsai, I.M. Samokhvalov, and G. Oliver. 2007. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 21:2422-2432.
-
(2007)
Genes Dev
, vol.21
, pp. 2422-2432
-
-
Srinivasan, R.S.1
Dillard, M.E.2
Lagutin, O.V.3
Lin, F.J.4
Tsai, S.5
Tsai, M.J.6
Samokhvalov, I.M.7
Oliver, G.8
-
90
-
-
77950469880
-
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells
-
Srinivasan, R.S., X. Geng, Y. Yang, Y. Wang, S. Mukatira, M. Studer, M.P. Porto, O. Lagutin, and G. Oliver. 2010. The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev. 24:696-707.
-
(2010)
Genes Dev
, vol.24
, pp. 696-707
-
-
Srinivasan, R.S.1
Geng, X.2
Yang, Y.3
Wang, Y.4
Mukatira, S.5
Studer, M.6
Porto, M.P.7
Lagutin, O.8
Oliver, G.9
-
91
-
-
77955301210
-
Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets
-
Suzuki-Inoue, K., O. Inoue, G. Ding, S. Nishimura, K. Hokamura, K. Eto, H. Kashiwagi, Y. Tomiyama, Y. Yatomi, K. Umemura, et al. 2010. Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. J. Biol. Chem. 285:24494-24507.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 2449424507
-
-
Suzuki-Inoue, K.1
Inoue, O.2
Ding, G.3
Nishimura, S.4
Hokamura, K.5
Eto, K.6
Kashiwagi, H.7
Tomiyama, Y.8
Yatomi, Y.9
Umemura, K.10
-
92
-
-
76749083490
-
Lymphangiogenesis: Molecular mechanisms and future promise
-
Tammela, T., and K. Alitalo. 2010. Lymphangiogenesis: Molecular mechanisms and future promise. Cell. 140:460-476.
-
(2010)
Cell
, vol.140
, pp. 460-476
-
-
Tammela, T.1
Alitalo, K.2
-
93
-
-
34250165403
-
Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signaling
-
Taniguchi, K., R. Kohno, T. Ayada, R. Kato, K. Ichiyama, T. Morisada, Y. Oike, Y. Yonemitsu, Y. Maehara, and A. Yoshimura. 2007. Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signaling. Mol. Cell. Biol. 27:4541-4550.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4541-4550
-
-
Taniguchi, K.1
Kohno, R.2
Ayada, T.3
Kato, R.4
Ichiyama, K.5
Morisada, T.6
Oike, Y.7
Yonemitsu, Y.8
Maehara, Y.9
Yoshimura, A.10
-
94
-
-
76749148097
-
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation
-
Uhrin, P., J. Zaujec, J.M. Breuss, D. Olcaydu, P. Chrenek, H. Stockinger, E. Fuertbauer, M. Moser, P. Haiko, R. Fässler, et al. 2010. Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood. 115:3997-4005.
-
(2010)
Blood
, vol.115
, pp. 3997-4005
-
-
Uhrin, P.1
Zaujec, J.2
Breuss, J.M.3
Olcaydu, D.4
Chrenek, P.5
Stockinger, H.6
Fuertbauer, E.7
Moser, M.8
Haiko, P.9
Fässler, R.10
-
95
-
-
71749099238
-
Novel missense mutations in the FOXC2 gene alter transcriptional activity
-
van Steensel, M.A., R.J. Damstra, M.V. Heitink, R.S. Bladergroen, J. Veraart, P.M. Steijlen, and M. van Geel. 2009. Novel missense mutations in the FOXC2 gene alter transcriptional activity. Hum. Mutat. 30:E1002-E1009.
-
(2009)
Hum. Mutat.
, vol.30
-
-
van Steensel, M.A.1
Damstra, R.J.2
Heitink, M.V.3
Bladergroen, R.S.4
Veraart, J.5
Steijlen, P.M.6
van Geel, M.7
-
96
-
-
3042738138
-
Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma
-
Wang, H.W., M.W. Trotter, D. Lagos, D. Bourboulia, S. Henderson, T. Mäkinen, S. Elliman, A.M. Flanagan, K. Alitalo, and C. Boshoff. 2004. Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nat. Genet. 36:687-693.
-
(2004)
Nat. Genet.
, vol.36
, pp. 687-693
-
-
Wang, H.W.1
Trotter, M.W.2
Lagos, D.3
Bourboulia, D.4
Henderson, S.5
Mäkinen, T.6
Elliman, S.7
Flanagan, A.M.8
Alitalo, K.9
Boshoff, C.10
-
97
-
-
77953029002
-
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis
-
Wang, Y., M. Nakayama, M.E. Pitulescu, T.S. Schmidt, M.L. Bochenek, A. Sakakibara, S. Adams, A. Davy, U. Deutsch, U. Lüthi, et al. 2010. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature. 465:483-486.
-
(2010)
Nature
, vol.465
, pp. 483-486
-
-
Wang, Y.1
Nakayama, M.2
Pitulescu, M.E.3
Schmidt, T.S.4
Bochenek, M.L.5
Sakakibara, A.6
Adams, S.7
Davy, A.8
Deutsch, U.9
Lüthi, U.10
-
98
-
-
0033578853
-
Prox1 function is required for the development of the murine lymphatic system
-
Wigle, J.T., and G. Oliver. 1999. Prox1 function is required for the development of the murine lymphatic system. Cell. 98:769-778.
-
(1999)
Cell
, vol.98
, pp. 769-778
-
-
Wigle, J.T.1
Oliver, G.2
-
99
-
-
0033018615
-
Prox1 function is crucial for mouse lens-fibre elongation
-
Wigle, J.T., K. Chowdhury, P. Gruss, and G. Oliver. 1999. Prox1 function is crucial for mouse lens-fibre elongation. Nat. Genet. 21:318-322.
-
(1999)
Nat. Genet.
, vol.21
, pp. 318-322
-
-
Wigle, J.T.1
Chowdhury, K.2
Gruss, P.3
Oliver, G.4
-
100
-
-
34250370123
-
Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
-
Wirzenius, M., T. Tammela, M. Uutela, Y. He, T. Odorisio, G. Zambruno, J.A. Nagy, H.F. Dvorak, S. Ylä-Herttuala, M. Shibuya, and K. Alitalo. 2007. Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting. J. Exp. Med. 204:1431-1440.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1431-1440
-
-
Wirzenius, M.1
Tammela, T.2
Uutela, M.3
He, Y.4
Odorisio, T.5
Zambruno, G.6
Nagy, J.A.7
Dvorak, H.F.8
Ylä-Herttuala, S.9
Shibuya, M.10
Alitalo, K.11
-
101
-
-
75749124699
-
Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3
-
Xu, Y., L. Yuan, J. Mak, L. Pardanaud, M. Caunt, I. Kasman, B. Larrivée, R. Del Toro, S. Suchting, A. Medvinsky, et al. 2010. Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3. J. Cell Biol. 188:115-130.
-
(2010)
J. Cell Biol.
, vol.188
, pp. 115-130
-
-
Xu, Y.1
Yuan, L.2
Mak, J.3
Pardanaud, L.4
Caunt, M.5
Kasman, I.6
Larrivée, B.7
Del Toro, R.8
Suchting, S.9
Medvinsky, A.10
-
102
-
-
61449109981
-
COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction
-
Yamazaki, T., Y. Yoshimatsu, Y. Morishita, K. Miyazono, and T. Watabe. 2009. COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction. Genes Cells. 14:425-434.
-
(2009)
Genes Cells
, vol.14
, pp. 425-434
-
-
Yamazaki, T.1
Yoshimatsu, Y.2
Morishita, Y.3
Miyazono, K.4
Watabe, T.5
-
103
-
-
33744967506
-
Live imaging of lymphatic development in the zebrafish
-
Yaniv, K., S. Isogai, D. Castranova, L. Dye, J. Hitomi, and B.M. Weinstein. 2006. Live imaging of lymphatic development in the zebrafish. Nat. Med. 12:711-716.
-
(2006)
Nat. Med.
, vol.12
, pp. 711-716
-
-
Yaniv, K.1
Isogai, S.2
Castranova, D.3
Dye, L.4
Hitomi, J.5
Weinstein, B.M.6
-
104
-
-
77958124039
-
Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus
-
Yoo, J., J. Kang, H.N. Lee, B. Aguilar, D. Kafka, S. Lee, I. Choi, J. Lee, S. Ramu, J. Haas, et al. 2010. Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. PLoS Pathog. 6: e1001046.
-
(2010)
PLoS Pathog
, vol.6
, pp. 1001046
-
-
Yoo, J.1
Kang, J.2
Lee, H.N.3
Aguilar, B.4
Kafka, D.5
Lee, S.6
Choi, I.7
Lee, J.8
Ramu, S.9
Haas, J.10
-
105
-
-
62449318120
-
Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells
-
Yu, J.J., V.A. Robb, T.A. Morrison, E.A. Ariazi, M. Karbowniczek, A. Astrinidis, C. Wang, L. Hernandez-Cuebas, L.F. Seeholzer, E. Nicolas, et al. 2009. Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells. Proc. Natl. Acad. Sci. USA. 106:2635-2640.
-
(2009)
Proc. Natl. Acad. Sci. USA.
, vol.106
, pp. 2635-2640
-
-
Yu, J.J.1
Robb, V.A.2
Morrison, T.A.3
Ariazi, E.A.4
Karbowniczek, M.5
Astrinidis, A.6
Wang, C.7
Hernandez-Cuebas, L.8
Seeholzer, L.F.9
Nicolas, E.10
-
106
-
-
0036803751
-
Abnormal lymphatic vessel development in neuropilin 2 mutant mice
-
Yuan, L., D. Moyon, L. Pardanaud, C. Bréant, M.J. Karkkainen, K. Alitalo, and A. Eichmann. 2002. Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development. 129:4797-4806.
-
(2002)
Development
, vol.129
, pp. 4797-4806
-
-
Yuan, L.1
Moyon, D.2
Pardanaud, L.3
Bréant, C.4
Karkkainen, M.J.5
Alitalo, K.6
Eichmann, A.7
-
107
-
-
67650848377
-
Contractile physiology of lymphatics
-
Zawieja, D.C. 2009. Contractile physiology of lymphatics. Lymphat. Res. Biol. 7:87-96.
-
(2009)
Lymphat. Res. Biol.
, vol.7
, pp. 87-96
-
-
Zawieja, D.C.1
-
108
-
-
78649899926
-
VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis
-
Zhang, L., F. Zhou, W. Han, B. Shen, J. Luo, M. Shibuya, and Y. He. 2010. VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis. Cell Res. 20:1319-1331.
-
(2010)
Cell Res
, vol.20
, pp. 1319-1331
-
-
Zhang, L.1
Zhou, F.2
Han, W.3
Shen, B.4
Luo, J.5
Shibuya, M.6
He, Y.7
-
109
-
-
77957365795
-
Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development
-
Zhou, F., Z. Chang, L. Zhang, Y.K. Hong, B. Shen, B. Wang, F. Zhang, G. Lu, D. Tvorogov, K. Alitalo, et al. 2010. Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development. Am. J. Pathol. 177:2124-2133.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 2124-2133
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Zhou, F.1
Chang, Z.2
Zhang, L.3
Hong, Y.K.4
Shen, B.5
Wang, B.6
Zhang, F.7
Lu, G.8
Tvorogov, D.9
Alitalo, K.10
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