-
1
-
-
26244456551
-
Molecular biology of the blood-brain barrier
-
Pardridge WM. Molecular biology of the blood-brain barrier. Mol Biotechnol 2005; 30: 57-70.
-
(2005)
Mol Biotechnol
, vol.30
, pp. 57-70
-
-
Pardridge, W.M.1
-
2
-
-
0037119577
-
Drug targeting. Breaking down barriers
-
Miller G. Drug targeting. Breaking down barriers. Science 2002; 297: 1116-1118.
-
(2002)
Science
, vol.297
, pp. 1116-1118
-
-
Miller, G.1
-
3
-
-
33748452503
-
Molecular Trojan horses for blood-brain barrier drug delivery
-
Pardridge WM. Molecular Trojan horses for blood-brain barrier drug delivery. Curr Opin Pharmacol 2006; 6: 494-500.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 494-500
-
-
Pardridge, W.M.1
-
4
-
-
34250665873
-
Targeted delivery of proteins across the blood-brain barrier
-
Spencer BJ, Verma IM. Targeted delivery of proteins across the blood-brain barrier. Proc Natl Acad Sci USA 2007; 104: 7594-7599.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7594-7599
-
-
Spencer, B.J.1
Verma, I.M.2
-
5
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
Epub Jun 17
-
Kumar P, Wu H, McBride JL, et al. Transvascular delivery of small interfering RNA to the central nervous system. Nature 2007; 448: 39-43. Epub 2007 Jun 17.
-
(2007)
Nature 2007
, vol.448
, pp. 39-43
-
-
Kumar, P.1
Wu, H.2
McBride, J.L.3
-
6
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to exogenous peroxidase
-
Reese TS, Karnovsky MJ. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol 1967; 34: 207-217.
-
(1967)
J Cell Biol
, vol.34
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
7
-
-
0035119379
-
Drug delivery via the blood-brain barrier
-
Edwards RH. Drug delivery via the blood-brain barrier. Nat Neurosci 2001; 4: 221-222.
-
(2001)
Nat Neurosci
, vol.4
, pp. 221-222
-
-
Edwards, R.H.1
-
8
-
-
0036627211
-
Tight junctions of the blood-brain barrier: Development, composition and regulation
-
Wolburg H, Lippoldt A. Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol 2002; 38: 323-337.
-
(2002)
Vascul Pharmacol
, vol.38
, pp. 323-337
-
-
Wolburg, H.1
Lippoldt, A.2
-
9
-
-
0038273906
-
Holey barrier: Claudins and the regulation of brain endothelial permeability
-
Matter K, Balda MS. Holey barrier: claudins and the regulation of brain endothelial permeability. J Cell Biol 2003; 161: 459-460.
-
(2003)
J Cell Biol
, vol.161
, pp. 459-460
-
-
Matter, K.1
Balda, M.S.2
-
10
-
-
0030734979
-
PDZ domains and the formation of protein networks at the plasma membrane
-
Fanning AS, Anderson JM. PDZ domains and the formation of protein networks at the plasma membrane. Curr Topics Microbiol Immunol 1998; 228: 209-233.
-
(1998)
Curr Topics Microbiol Immunol
, vol.228
, pp. 209-233
-
-
Fanning, A.S.1
Anderson, J.M.2
-
11
-
-
0034722381
-
Tight junction, a platform for trafficking and signaling protein complexes
-
Zahraoui A, Louvard D, Galli T. Tight junction, a platform for trafficking and signaling protein complexes. J Cell Biol 2000; 151: F31-36.
-
(2000)
J Cell Biol
, vol.151
-
-
Zahraoui, A.1
Louvard, D.2
Galli, T.3
-
12
-
-
33645553318
-
Endothelial tight junctions: Permeable barriers of the vessel wall
-
Bazzoni G. Endothelial tight junctions: permeable barriers of the vessel wall. Thromb Haemost 2006; 95: 36-42.
-
(2006)
Thromb Haemost
, vol.95
, pp. 36-42
-
-
Bazzoni, G.1
-
13
-
-
0035823043
-
Connexin45 directly binds to ZO-1 and localizes to the tight junction region in epithelial MDCK cells
-
Kausalya PJ, Reichert M, Hunziker W. Connexin45 directly binds to ZO-1 and localizes to the tight junction region in epithelial MDCK cells. FEBS Lett 2001; 505: 92-96.
-
(2001)
FEBS Lett
, vol.505
, pp. 92-96
-
-
Kausalya, P.J.1
Reichert, M.2
Hunziker, W.3
-
14
-
-
3042856468
-
Barriers built on claudins
-
Turksen K, Troy TC. Barriers built on claudins. J Cell Sci 2004; 117: 2435-2447.
-
(2004)
J Cell Sci
, vol.117
, pp. 2435-2447
-
-
Turksen, K.1
Troy, T.C.2
-
15
-
-
0037648580
-
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice
-
Nitta T, Hata M, Gotoh S, et al. Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol 2003; 161: 653-660.
-
(2003)
J Cell Biol
, vol.161
, pp. 653-660
-
-
Nitta, T.1
Hata, M.2
Gotoh, S.3
-
16
-
-
34247842900
-
Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells
-
Koto T, Takubo K, Ishida S, et al. Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells. Am J Pathol 2007; 170: 1389-1397.
-
(2007)
Am J Pathol
, vol.170
, pp. 1389-1397
-
-
Koto, T.1
Takubo, K.2
Ishida, S.3
-
17
-
-
0035354574
-
Molecular structure of tight junctions and their role in epithelial transport
-
Anderson JM. Molecular structure of tight junctions and their role in epithelial transport. News Physiol Sci 2001; 16: 126-130.
-
(2001)
News Physiol Sci
, vol.16
, pp. 126-130
-
-
Anderson, J.M.1
-
19
-
-
33846022383
-
Gene therapy progress and prospects: Hydrodynamic gene delivery
-
Herweijer H, Wolff JA. Gene therapy progress and prospects: hydrodynamic gene delivery. Gene Ther 2007; 14: 99-107.
-
(2007)
Gene Ther
, vol.14
, pp. 99-107
-
-
Herweijer, H.1
Wolff, J.A.2
-
20
-
-
0032547833
-
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts
-
Furuse M, Sasaki H, Fujimoto K, Tsukita S. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol 1998; 143: 391-401.
-
(1998)
J Cell Biol
, vol.143
, pp. 391-401
-
-
Furuse, M.1
Sasaki, H.2
Fujimoto, K.3
Tsukita, S.4
-
21
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat Genet 2002; 32: 107-108.
-
(2002)
Nat Genet
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
22
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey AP, Meuse L, Pham TT, Conklin DS, Hannon GJ, Kay MA. RNA interference in adult mice. Nature 2002; 418: 38-39.
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
Meuse, L.2
Pham, T.T.3
Conklin, D.S.4
Hannon, G.J.5
Kay, M.A.6
-
23
-
-
23844529037
-
Toward a gene therapy for dominant disease: Validation of an RNA interference-based mutation-independent approach
-
Kiang AS, Palfi A, Ader M, et al. Toward a gene therapy for dominant disease: validation of an RNA interference-based mutation-independent approach. Mol Ther 2005; 12: 555-561.
-
(2005)
Mol Ther
, vol.12
, pp. 555-561
-
-
Kiang, A.S.1
Palfi, A.2
Ader, M.3
-
24
-
-
29244483102
-
In vivo delivery of small interfering RNA targeting brain capillary endothelial cells
-
Hino T, Yokota T, Ito S, et al. In vivo delivery of small interfering RNA targeting brain capillary endothelial cells. Biochem Biophys Res Commun 2006; 340: 263-267.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 263-267
-
-
Hino, T.1
Yokota, T.2
Ito, S.3
-
25
-
-
0035292828
-
Delivery of peptides and proteins through the blood-brain barrier
-
Bickel U, Yoshikawa T, Pardridge WM. Delivery of peptides and proteins through the blood-brain barrier. Adv Drug Deliv Rev 2001; 46: 247-279.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, pp. 247-279
-
-
Bickel, U.1
Yoshikawa, T.2
Pardridge, W.M.3
-
26
-
-
0032754657
-
Microvessel organization and structure in experimental brain tumors: Microvessel populations with distinctive structural and functional properties
-
Schlageter KE, Molnar P, Lapin GD, Groothuis DR. Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties. Microvasc Res 1999; 58: 312-328.
-
(1999)
Microvasc Res
, vol.58
, pp. 312-328
-
-
Schlageter, K.E.1
Molnar, P.2
Lapin, G.D.3
Groothuis, D.R.4
-
27
-
-
33749516287
-
Limited contribution of claudin-5-dependent tight junction strands to endothelial barrier function
-
Epub Sep 7
-
Fontijn RD, Rohlena J, van Marle J, Pannekoek H, Horrevoets AJ. Limited contribution of claudin-5-dependent tight junction strands to endothelial barrier function. Eur J Cell Biol 2006; 85: 1131-1144. Epub 2006 Sep 7.
-
(2006)
Eur J Cell Biol 2006
, vol.85
, pp. 1131-1144
-
-
Fontijn, R.D.1
Rohlena, J.2
van Marle, J.3
Pannekoek, H.4
Horrevoets, A.J.5
-
28
-
-
0031172452
-
Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome
-
Sirotkin H, Morrow B, Saint-Jore B, et al. Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Genomics 1997; 42: 245-251.
-
(1997)
Genomics
, vol.42
, pp. 245-251
-
-
Sirotkin, H.1
Morrow, B.2
Saint-Jore, B.3
-
29
-
-
34247556445
-
Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone
-
Epub Feb 28
-
Scalabrino GA, Hogan N, O'Boyle KM, et al. Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone. Neuropharmacology 2007; 52: 1472-81. Epub 2007 Feb 28.
-
(2007)
Neuropharmacology 2007
, vol.52
, pp. 1472-1481
-
-
Scalabrino, G.A.1
Hogan, N.2
O'Boyle, K.M.3
-
30
-
-
84989298619
-
Blood-brain permeability of [3H]-(3-methyl-His2)thyrotropin-releasing hormone (MeTRH) in mice: Effects of TRH and its analogues
-
Urayama A, Yamada S, Ohmori Y, Deguchi Y, Uchida S, Kimura R. Blood-brain permeability of [3H]-(3-methyl-His2)thyrotropin-releasing hormone (MeTRH) in mice: effects of TRH and its analogues. Drug Metab Pharmacokinet 2003; 18: 310-318.
-
(2003)
Drug Metab Pharmacokinet
, vol.18
, pp. 310-318
-
-
Urayama, A.1
Yamada, S.2
Ohmori, Y.3
Deguchi, Y.4
Uchida, S.5
Kimura, R.6
-
31
-
-
0027751753
-
Evidence for predominantly paracellular transport of thyrotropin-releasing hormone across CACO-2 cell monolayers
-
Gan LS, Niederer T, Eads C, Thakker D. Evidence for predominantly paracellular transport of thyrotropin-releasing hormone across CACO-2 cell monolayers. Biochem Biophys Res Commun 1993; 197: 771-777.
-
(1993)
Biochem Biophys Res Commun
, vol.197
, pp. 771-777
-
-
Gan, L.S.1
Niederer, T.2
Eads, C.3
Thakker, D.4
-
32
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A, Leake D, Boese Q, Scaringe S, Marshall WS, Khvorova A. Rational siRNA design for RNA interference. Nat Biotechnol 2004; 22: 326-330.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
33
-
-
33645224383
-
RNAi-based suppression and replacement of rds-peripherin in retinal organotypic culture
-
Palfi A, Ader M, Kiang AS. RNAi-based suppression and replacement of rds-peripherin in retinal organotypic culture. Hum Mutat 2006; 27: 260-268.
-
(2006)
Hum Mutat
, vol.27
, pp. 260-268
-
-
Palfi, A.1
Ader, M.2
Kiang, A.S.3
-
34
-
-
34347246364
-
RNA-interference mediated suppression and replacement of human rhodopsin in vivo
-
Epub May 23
-
O'Reilly M, Palfi A, Chadderton N, et al. RNA-interference mediated suppression and replacement of human rhodopsin in vivo. Am J Hum Genet 2007; 81: 127-135. Epub 2007 May 23.
-
(2007)
Am J Hum Genet 2007
, vol.81
, pp. 127-135
-
-
O'Reilly, M.1
Palfi, A.2
Chadderton, N.3
|