-
1
-
-
42349112088
-
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, et al. (2008) Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nature Reviews Genetics 9: 356-69.
-
(2008)
Nature Reviews Genetics
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
-
2
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher PM, Brown Ma, McCarthy MI, Yang J, (2012) Five years of GWAS discovery. American journal of human genetics 90: 7-24.
-
(2012)
American Journal of Human Genetics
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.2
McCarthy, M.I.3
Yang, J.4
-
3
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio Ta, Collins FS, Cox NJ, Hindorff LA, Goldstein DB, et al. (2009) Finding the missing heritability of complex diseases. Nature 461: 747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.1
Collins, F.S.2
Cox, N.J.3
Hindorff, L.A.4
Goldstein, D.B.5
-
5
-
-
70249134919
-
Molecular networks as sensors and drivers of common human diseases
-
Schadt EE, (2009) Molecular networks as sensors and drivers of common human diseases. Nature 461: 218-23.
-
(2009)
Nature
, vol.461
, pp. 218-223
-
-
Schadt, E.E.1
-
6
-
-
78549251736
-
Analysing biological pathways in genome-wide association studies
-
Wang K, Li M, Hakonarson H, (2010) Analysing biological pathways in genome-wide association studies. Nature Reviews Genetics 11: 843-854.
-
(2010)
Nature Reviews Genetics
, vol.11
, pp. 843-854
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
7
-
-
79960644911
-
Gene set analysis of SNP data: benefits, challenges, and future directions
-
Fridley BL, Biernacka JM, (2011) Gene set analysis of SNP data: benefits, challenges, and future directions. European journal of human genetics: EJHG 19: 837-843.
-
(2011)
European Journal of Human Genetics: EJHG
, vol.19
, pp. 837-843
-
-
Fridley, B.L.1
Biernacka, J.M.2
-
8
-
-
78751507648
-
Mining Gold Dust Under the Genome Wide Significance Level: A Two-Stage Approach to Analysis of GWAS
-
Shi G, Boerwinkle E, Morrison AC, Gu CC, Chakravarti A, et al. (2011) Mining Gold Dust Under the Genome Wide Significance Level: A Two-Stage Approach to Analysis of GWAS. Genetic epidemiology 35: 117-118.
-
(2011)
Genetic Epidemiology
, vol.35
, pp. 117-118
-
-
Shi, G.1
Boerwinkle, E.2
Morrison, A.C.3
Gu, C.C.4
Chakravarti, A.5
-
9
-
-
77955639976
-
Joint identification of multiple genetic variants via elastic-net variable selection in a genome-wide association analysis
-
Cho S, Kim K, Kim YJ, Lee JK, Cho YS, et al. (2010) Joint identification of multiple genetic variants via elastic-net variable selection in a genome-wide association analysis. Annals of human genetics 74: 416-28.
-
(2010)
Annals of Human Genetics
, vol.74
, pp. 416-428
-
-
Cho, S.1
Kim, K.2
Kim, Y.J.3
Lee, J.K.4
Cho, Y.S.5
-
10
-
-
78649523088
-
SNP selection in genome-wide and candidate gene studies via penalized logistic regression
-
Ayers KL, Cordell HJ, (2010) SNP selection in genome-wide and candidate gene studies via penalized logistic regression. Genetic epidemiology 34: 879-91.
-
(2010)
Genetic Epidemiology
, vol.34
, pp. 879-891
-
-
Ayers, K.L.1
Cordell, H.J.2
-
11
-
-
62549115747
-
Genome-wide association analysis by lasso penalized logistic regression
-
Wu TT, Chen YF, Hastie T, Sobel E, Lange K, (2009) Genome-wide association analysis by lasso penalized logistic regression. Bioinformatics (Oxford, England) 25: 714-21.
-
(2009)
Bioinformatics (Oxford, England)
, vol.25
, pp. 714-721
-
-
Wu, T.T.1
Chen, Y.F.2
Hastie, T.3
Sobel, E.4
Lange, K.5
-
14
-
-
12844266177
-
Sparsity and smoothness via the fused lasso
-
Tibshirani R, Saunders M, Rosset S, Zhu J, Knight K, (2005) Sparsity and smoothness via the fused lasso. Journal of the Royal Statistical Society: Series B (Statistical Methodology) 67: 91-108.
-
(2005)
Journal of the Royal Statistical Society: Series B (Statistical Methodology)
, vol.67
, pp. 91-108
-
-
Tibshirani, R.1
Saunders, M.2
Rosset, S.3
Zhu, J.4
Knight, K.5
-
15
-
-
37249032736
-
Spatial smoothing and hot spot detection for CGH data using the fused lasso
-
Tibshirani R, Wang P, (2008) Spatial smoothing and hot spot detection for CGH data using the fused lasso. Biostatistics (Oxford, England) 9: 18-29.
-
(2008)
Biostatistics (Oxford, England)
, vol.9
, pp. 18-29
-
-
Tibshirani, R.1
Wang, P.2
-
16
-
-
77953123145
-
Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data
-
Chen LS, Hutter CM, Potter JD, Liu Y, Prentice RL, et al. (2010) Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data. American Journal of Human Genetics 86: 860-871.
-
(2010)
American Journal of Human Genetics
, vol.86
, pp. 860-871
-
-
Chen, L.S.1
Hutter, C.M.2
Potter, J.D.3
Liu, Y.4
Prentice, R.L.5
-
17
-
-
84867345007
-
Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression
-
Silver M, Janousova E, Hua X, Thompson PM, Montana G, (2012) Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression. NeuroImage 63: 1681-1694.
-
(2012)
NeuroImage
, vol.63
, pp. 1681-1694
-
-
Silver, M.1
Janousova, E.2
Hua, X.3
Thompson, P.M.4
Montana, G.5
-
18
-
-
77951210494
-
Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inammatory diseases
-
Eleftherohorinou H, Wright V, Hoggart C, Hartikainen AL, Jarvelin MR, et al. (2009) Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inammatory diseases. PloS one 4: e8068.
-
(2009)
PloS One
, vol.4
-
-
Eleftherohorinou, H.1
Wright, V.2
Hoggart, C.3
Hartikainen, A.L.4
Jarvelin, M.R.5
-
19
-
-
80051683088
-
Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways
-
Eleftherohorinou H, Hoggart CJ, Wright VJ, Levin M, Coin LJM, (2011) Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways. Human molecular genetics 20 (17) (): 3494-506.
-
(2011)
Human Molecular Genetics
, vol.20
, Issue.17
, pp. 3494-3506
-
-
Eleftherohorinou, H.1
Hoggart, C.J.2
Wright, V.J.3
Levin, M.4
Coin, L.J.M.5
-
21
-
-
77953694851
-
A note on the group lasso and a sparse group lasso
-
Friedman J, Hastie T, Tibshirani R, (2010) A note on the group lasso and a sparse group lasso. pp. 1-8.
-
(2010)
, pp. 1-8
-
-
Friedman, J.1
Hastie, T.2
Tibshirani, R.3
-
22
-
-
77957233032
-
Association Screening of Common and Rare Genetic Variants by Penalized Regression
-
Zhou H, Sehl ME, Sinsheimer JS, Lange K, (2010) Association Screening of Common and Rare Genetic Variants by Penalized Regression. Bioinformatics (Oxford, England) 26: 2375-2382.
-
(2010)
Bioinformatics (Oxford, England)
, vol.26
, pp. 2375-2382
-
-
Zhou, H.1
Sehl, M.E.2
Sinsheimer, J.S.3
Lange, K.4
-
23
-
-
78651272402
-
Regularized multivariate regression for identifying master predictors with application to integrative genomics study of breast cancer
-
Peng J, Zhu J, Bergamaschi A, Han W, Noh DY, et al. (2010) Regularized multivariate regression for identifying master predictors with application to integrative genomics study of breast cancer. The Annals of Applied Statistics 4: 53-77.
-
(2010)
The Annals of Applied Statistics
, vol.4
, pp. 53-77
-
-
Peng, J.1
Zhu, J.2
Bergamaschi, A.3
Han, W.4
Noh, D.Y.5
-
25
-
-
69949155103
-
The composite absolute penalties family for grouped and hierarchical variable selection
-
Zhao P, Rocha G, Yu B, (2009) The composite absolute penalties family for grouped and hierarchical variable selection. The Annals of Statistics 37: 3468-3497.
-
(2009)
The Annals of Statistics
, vol.37
, pp. 3468-3497
-
-
Zhao, P.1
Rocha, G.2
Yu, B.3
-
27
-
-
80555129673
-
Structured Variable Selection with Sparsity-Inducing Norms
-
Jenatton R, Bach F, (2011) Structured Variable Selection with Sparsity-Inducing Norms. Journal of Machine Learning Research 12: 2777-2824.
-
(2011)
Journal of Machine Learning Research
, vol.12
, pp. 2777-2824
-
-
Jenatton, R.1
Bach, F.2
-
28
-
-
84876501705
-
Hierarchical modeling identifies novel lung cancer susceptibility variants in inammation pathways among 10,140 cases and 11,012 controls
-
Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, et al. (2013) Hierarchical modeling identifies novel lung cancer susceptibility variants in inammation pathways among 10,140 cases and 11,012 controls. Human genetics 32 (5) (): 579-89.
-
(2013)
Human Genetics
, vol.32
, Issue.5
, pp. 579-589
-
-
Brenner, D.R.1
Brennan, P.2
Boffetta, P.3
Amos, C.I.4
Spitz, M.R.5
-
29
-
-
79951966907
-
An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies
-
Wang L, Jia P, Wolfinger RD, Chen X, Grayson BL, et al. (2011) An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies. Bioinformatics (Oxford, England) 27: 686-92.
-
(2011)
Bioinformatics (Oxford, England)
, vol.27
, pp. 686-692
-
-
Wang, L.1
Jia, P.2
Wolfinger, R.D.3
Chen, X.4
Grayson, B.L.5
-
30
-
-
84864868742
-
Fast Identification of Biological Pathways Associated with a Quantitative Trait Using Group Lasso with Overlaps
-
Article 7,doi: 10.2202/1544-6115.1755
-
Silver M, Montana G, (2012) Fast Identification of Biological Pathways Associated with a Quantitative Trait Using Group Lasso with Overlaps. Statistical Applications in Genetics and Molecular Biology 11 (1) (): Article 7 doi: 10.2202/1544-6115.1755.
-
(2012)
Statistical Applications in Genetics and Molecular Biology
, vol.11
, Issue.1
-
-
Silver, M.1
Montana, G.2
-
31
-
-
27744467283
-
Cardiology patient page. The "good cholesterol": high-density lipoprotein
-
Toth PP, (2005) Cardiology patient page. The "good cholesterol": high-density lipoprotein. Circulation 111: e89-91.
-
(2005)
Circulation
, vol.111
-
-
Toth, P.P.1
-
32
-
-
0021871543
-
The Collaborative Lipid Research Clinics Family Study: biological and cultural determinants of familial resemblance for plasma lipids and lipoproteins
-
Namboodiri KK, Kaplan EB, Heuch I, Elston RC, Green PP, et al. (1985) The Collaborative Lipid Research Clinics Family Study: biological and cultural determinants of familial resemblance for plasma lipids and lipoproteins. Genetic epidemiology 2: 227-54.
-
(1985)
Genetic Epidemiology
, vol.2
, pp. 227-254
-
-
Namboodiri, K.K.1
Kaplan, E.B.2
Heuch, I.3
Elston, R.C.4
Green, P.P.5
-
33
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences of the United States of America 106: 9362-7.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
-
34
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, et al. (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466: 707-13.
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
Edmondson, A.C.4
Stylianou, I.M.5
-
35
-
-
46749146509
-
A coordinate gradient descent method for nonsmooth separable minimization
-
Tseng P, Yun S, (2009) A coordinate gradient descent method for nonsmooth separable minimization. Mathematical Programming 117: 387-423.
-
(2009)
Mathematical Programming
, vol.117
, pp. 387-423
-
-
Tseng, P.1
Yun, S.2
-
37
-
-
79953645463
-
Identifying causal genes and dysregulated pathways in complex diseases
-
Kim YA, Wuchty S, Przytycka TM, (2011) Identifying causal genes and dysregulated pathways in complex diseases. PLoS computational biology 7: e1001095.
-
(2011)
PLoS Computational Biology
, vol.7
-
-
Kim, Y.A.1
Wuchty, S.2
Przytycka, T.M.3
-
38
-
-
33746525415
-
Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways
-
Lehner B, Crombie C, Tischler J, Fortunato A, Fraser AG, (2006) Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nature genetics 38: 896-903.
-
(2006)
Nature Genetics
, vol.38
, pp. 896-903
-
-
Lehner, B.1
Crombie, C.2
Tischler, J.3
Fortunato, A.4
Fraser, A.G.5
-
39
-
-
61549115034
-
Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease
-
Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, et al. (2009) Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease. American journal of human genetics 84: 399-405.
-
(2009)
American Journal of Human Genetics
, vol.84
, pp. 399-405
-
-
Wang, K.1
Zhang, H.2
Kugathasan, S.3
Annese, V.4
Bradfield, J.P.5
-
40
-
-
67649584052
-
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder
-
Holmans P, Green EK, Pahwa JS, Ferreira MaR, Purcell SM, et al. (2009) Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. American journal of human genetics 85: 13-24.
-
(2009)
American Journal of Human Genetics
, vol.85
, pp. 13-24
-
-
Holmans, P.1
Green, E.K.2
Pahwa, J.S.3
Ferreira, M.R.4
Purcell, S.M.5
-
41
-
-
78651259030
-
Pathway-based analysis using reduced gene subsets in genome-wide association studies
-
Zhao J, Gupta S, Seielstad M, Liu J, Thalamuthu A, (2011) Pathway-based analysis using reduced gene subsets in genome-wide association studies. BMC bioinformatics 12: 17.
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 17
-
-
Zhao, J.1
Gupta, S.2
Seielstad, M.3
Liu, J.4
Thalamuthu, A.5
-
42
-
-
84860470942
-
An Efficient Optimization Algorithm for Structured Sparse CCA, with Applications to eQTL Mapping
-
Chen X, Liu H, (2011) An Efficient Optimization Algorithm for Structured Sparse CCA, with Applications to eQTL Mapping. Statistics in Biosciences 4: 3-26.
-
(2011)
Statistics in Biosciences
, vol.4
, pp. 3-26
-
-
Chen, X.1
Liu, H.2
-
43
-
-
0003684449
-
-
Springer, New York, 2nd edition
-
Hastie T, Tibshirani R, Friedman J (2008) The Elements of Statistical Learning: Data Mining, Inference and Prediction. Springer, New York, 2nd edition.
-
(2008)
The Elements of Statistical Learning: Data Mining, Inference and Prediction
-
-
Hastie, T.1
Tibshirani, R.2
Friedman, J.3
-
44
-
-
84856108049
-
Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease
-
Vounou M, Janousova E, Wolz R, Stein JL, Thompson PM, et al. (2011) Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease. NeuroImage 60: 700-716.
-
(2011)
NeuroImage
, vol.60
, pp. 700-716
-
-
Vounou, M.1
Janousova, E.2
Wolz, R.3
Stein, J.L.4
Thompson, P.M.5
-
48
-
-
82455211260
-
LASSO model selection with postprocessing for a genome-wide association study data set
-
BioMed Central Ltd
-
Motyer AJ, McKendry C, Galbraith S, Wilson SR (2011) LASSO model selection with postprocessing for a genome-wide association study data set. In: BMC proceedings. BioMed Central Ltd, volume 5, p. S24.
-
(2011)
BMC proceedings
, vol.5
-
-
Motyer, A.J.1
McKendry, C.2
Galbraith, S.3
Wilson, S.R.4
-
49
-
-
80054719506
-
Stability selection for genome-wide association
-
Alexander DH, Lange K, (2011) Stability selection for genome-wide association. Genetic epidemiology 35: 722-8.
-
(2011)
Genetic Epidemiology
, vol.35
, pp. 722-728
-
-
Alexander, D.H.1
Lange, K.2
-
50
-
-
77954133026
-
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
-
Park JH, Wacholder S, Gail MH, Peters U, Jacobs KB, et al. (2010) Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nature genetics 42 (7) (): 570-5.
-
(2010)
Nature Genetics
, vol.42
, Issue.7
, pp. 570-575
-
-
Park, J.H.1
Wacholder, S.2
Gail, M.H.3
Peters, U.4
Jacobs, K.B.5
-
51
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, et al. (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460: 748-52.
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
Visscher, P.M.4
O'Donovan, M.C.5
-
52
-
-
79955638028
-
Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia
-
Sim X, Ong RTH, Suo C, Tay WT, Liu J, et al. (2011) Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. PLoS Genetics 7: e1001363.
-
(2011)
PLoS Genetics
, vol.7
-
-
Sim, X.1
Ong, R.T.H.2
Suo, C.3
Tay, W.T.4
Liu, J.5
-
53
-
-
70350710156
-
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations
-
Teo YY, Sim X, Ong RTH, Tan AKS, Chen J, et al. (2009) Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations. Genome research 19: 2154-62.
-
(2009)
Genome Research
, vol.19
, pp. 2154-2162
-
-
Teo, Y.Y.1
Sim, X.2
Ong, R.T.H.3
Tan, A.K.S.4
Chen, J.5
-
54
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, et al. (2007) A second generation human haplotype map of over 3.1 million SNPs. Nature 449: 851-61.
-
(2007)
Nature
, vol.449
, pp. 851-861
-
-
Frazer, K.A.1
Ballinger, D.G.2
Cox, D.R.3
Hinds, D.A.4
Stuve, L.L.5
-
55
-
-
84856478855
-
A linear complexity phasing method for thousands of genomes
-
Delaneau O, Marchini J, Zagury JF, (2012) A linear complexity phasing method for thousands of genomes. Nature methods 9: 179-81.
-
(2012)
Nature Methods
, vol.9
, pp. 179-181
-
-
Delaneau, O.1
Marchini, J.2
Zagury, J.F.3
-
56
-
-
84863845193
-
Genotype Imputation with Thousands of Genomes
-
Howie B, Marchini J, Stephens M, (2011) Genotype Imputation with Thousands of Genomes. G3 (Bethesda) 1: 457-469.
-
(2011)
G3 (Bethesda)
, vol.1
, pp. 457-469
-
-
Howie, B.1
Marchini, J.2
Stephens, M.3
-
57
-
-
84975742565
-
A map of human genome variation from populationscale sequencing
-
The 1000 Genomes Project Consortium
-
The 1000 Genomes Project Consortium (2011) A map of human genome variation from populationscale sequencing. Nature 467: 1061-1073.
-
(2011)
Nature
, vol.467
, pp. 1061-1073
-
-
-
58
-
-
73149103718
-
Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application
-
Cantor RM, Lange K, Sinsheimer JS, (2010) Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application. American Journal of Human Genetics 86: 6-22.
-
(2010)
American Journal of Human Genetics
, vol.86
, pp. 6-22
-
-
Cantor, R.M.1
Lange, K.2
Sinsheimer, J.S.3
-
59
-
-
77956480115
-
Consistency, comprehensiveness, and compatibility of pathway databases
-
Soh D, Dong D, Guo Y, Wong L, (2010) Consistency, comprehensiveness, and compatibility of pathway databases. BMC Bioinformatics 11: 449.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 449
-
-
Soh, D.1
Dong, D.2
Guo, Y.3
Wong, L.4
-
60
-
-
5044245707
-
Gene co-expression network topology provides a framework for molecular characterization of cellular state
-
Carter SL, Brechbühler CM, Griffn M, Bond AT, (2004) Gene co-expression network topology provides a framework for molecular characterization of cellular state. Bioinformatics (Oxford, England) 20: 2242-50.
-
(2004)
Bioinformatics (Oxford, England)
, vol.20
, pp. 2242-2250
-
-
Carter, S.L.1
Brechbühler, C.M.2
Griffn, M.3
Bond, A.T.4
-
61
-
-
0035799707
-
Lethality and centrality in protein networks
-
Jeong H, Mason SP, Barabási aL, Oltvai ZN, (2001) Lethality and centrality in protein networks. Nature 411: 41-2.
-
(2001)
Nature
, vol.411
, pp. 41-42
-
-
Jeong, H.1
Mason, S.P.2
Barabási, L.3
Oltvai, Z.N.4
-
62
-
-
38349106729
-
Algebraic stability indicators for ranked lists in molecular profiling
-
Jurman G, Merler S, Barla A, Paoli S, Galea A, et al. (2008) Algebraic stability indicators for ranked lists in molecular profiling. Bioinformatics (Oxford, England) 24: 258-64.
-
(2008)
Bioinformatics (Oxford, England)
, vol.24
, pp. 258-264
-
-
Jurman, G.1
Merler, S.2
Barla, A.3
Paoli, S.4
Galea, A.5
-
63
-
-
0001677717
-
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
-
Benjamini Y, Hochberg Y, (1995) Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing. Journal of the Royal Statistical Society, Series B 57: 289-300.
-
(1995)
Journal of the Royal Statistical Society, Series B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
64
-
-
84871564602
-
Theoretical properties of the overlapping groups lasso
-
Percival D, (2012) Theoretical properties of the overlapping groups lasso. Electronic Journal of Statistics 6: 269-288.
-
(2012)
Electronic Journal of Statistics
, vol.6
, pp. 269-288
-
-
Percival, D.1
-
65
-
-
84862252240
-
Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging
-
Valdar W, Sabourin J, Nobel A, Holmes CC, (2012) Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging. Genetic epidemiology 36: 451-62.
-
(2012)
Genetic Epidemiology
, vol.36
, pp. 451-462
-
-
Valdar, W.1
Sabourin, J.2
Nobel, A.3
Holmes, C.C.4
-
66
-
-
34249663294
-
Analyzing gene expression data in terms of gene sets: methodological issues
-
Goeman JJ, Bühlmann P, (2007) Analyzing gene expression data in terms of gene sets: methodological issues. Bioinformatics (Oxford, England) 23: 980-7.
-
(2007)
Bioinformatics (Oxford, England)
, vol.23
, pp. 980-987
-
-
Goeman, J.J.1
Bühlmann, P.2
-
67
-
-
84864422902
-
Comparison of methods for competitive tests of pathway analysis
-
Evangelou M, Rendon A, Ouwehand WH, Wernisch L, Dudbridge F, (2012) Comparison of methods for competitive tests of pathway analysis. PloS one 7: e41018.
-
(2012)
PloS One
, vol.7
-
-
Evangelou, M.1
Rendon, A.2
Ouwehand, W.H.3
Wernisch, L.4
Dudbridge, F.5
-
69
-
-
84857156980
-
Robust rank aggregation for gene list integration and meta-analysis
-
Kolde R, Laur S, Adler P, Vilo J, (2012) Robust rank aggregation for gene list integration and meta-analysis. Bioinformatics (Oxford, England) 28: 573-80.
-
(2012)
Bioinformatics (Oxford, England)
, vol.28
, pp. 573-580
-
-
Kolde, R.1
Laur, S.2
Adler, P.3
Vilo, J.4
-
71
-
-
27644587961
-
High-density lipoprotein function recent advances
-
Ansell BJ, Watson KE, Fogelman AM, Navab M, Fonarow GC, (2005) High-density lipoprotein function recent advances. Journal of the American College of Cardiology 46: 1792-8.
-
(2005)
Journal of the American College of Cardiology
, vol.46
, pp. 1792-1798
-
-
Ansell, B.J.1
Watson, K.E.2
Fogelman, A.M.3
Navab, M.4
Fonarow, G.C.5
-
72
-
-
0024501678
-
High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies
-
Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, Castelli WP, et al. (1989) High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation 79: 8-15.
-
(1989)
Circulation
, vol.79
, pp. 8-15
-
-
Gordon, D.J.1
Probstfield, J.L.2
Garrison, R.J.3
Neaton, J.D.4
Castelli, W.P.5
-
73
-
-
68249150838
-
Association of HDL cholesterol and triglycerides with mortality in patients with heart failure
-
Freitas H, Barbosa E, Rosa F, Lima A, Mansur A, (2009) Association of HDL cholesterol and triglycerides with mortality in patients with heart failure. Brazilian Journal of Medical and Biological Research 42: 420-425.
-
(2009)
Brazilian Journal of Medical and Biological Research
, vol.42
, pp. 420-425
-
-
Freitas, H.1
Barbosa, E.2
Rosa, F.3
Lima, A.4
Mansur, A.5
-
74
-
-
79955165490
-
Serum lipoprotein levels in takotsubo cardiomyopathy vs. myocardial infarction
-
Gaddam S, Nimmagadda KC, Nagrani T, Naqi M, Wetz RV, et al. (2011) Serum lipoprotein levels in takotsubo cardiomyopathy vs. myocardial infarction. International archives of medicine 4: 14.
-
(2011)
International Archives of Medicine
, vol.4
, pp. 14
-
-
Gaddam, S.1
Nimmagadda, K.C.2
Nagrani, T.3
Naqi, M.4
Wetz, R.V.5
-
75
-
-
0033998793
-
The role of lipid rafts in T cell antigen receptor (TCR) signalling
-
Janes PW, Ley SC, Magee AI, Kabouridis PS, (2000) The role of lipid rafts in T cell antigen receptor (TCR) signalling. Seminars in immunology 12: 23-34.
-
(2000)
Seminars in Immunology
, vol.12
, pp. 23-34
-
-
Janes, P.W.1
Ley, S.C.2
Magee, A.I.3
Kabouridis, P.S.4
-
76
-
-
33947097442
-
Lipid Rafts-Composition, Characterization, and Controversies
-
Calder PC, Yaqoob P, (2007) Lipid Rafts-Composition, Characterization, and Controversies. J Nutr 137: 545-547.
-
(2007)
J Nutr
, vol.137
, pp. 545-547
-
-
Calder, P.C.1
Yaqoob, P.2
-
77
-
-
0032506273
-
Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism
-
Staels B, Dallongeville J, Auwerx J, Schoonjans K, Leitersdorf E, et al. (1998) Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism. Circulation 98: 2088-2093.
-
(1998)
Circulation
, vol.98
, pp. 2088-2093
-
-
Staels, B.1
Dallongeville, J.2
Auwerx, J.3
Schoonjans, K.4
Leitersdorf, E.5
-
78
-
-
47949094965
-
Integration of metabolism and inammation by lipid-activated nuclear receptors
-
Bensinger SJ, Tontonoz P, (2008) Integration of metabolism and inammation by lipid-activated nuclear receptors. Nature 454: 470-7.
-
(2008)
Nature
, vol.454
, pp. 470-477
-
-
Bensinger, S.J.1
Tontonoz, P.2
-
79
-
-
5344223383
-
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
-
Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, et al. (2004) Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell 119: 19-31.
-
(2004)
Cell
, vol.119
, pp. 19-31
-
-
Splawski, I.1
Timothy, K.W.2
Sharpe, L.M.3
Decher, N.4
Kumar, P.5
-
80
-
-
33846627787
-
Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death
-
Antzelevitch C, Pollevick GD, Cordeiro JM, Casis O, Sanguinetti MC, et al. (2007) Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death. Circulation 115: 442-9.
-
(2007)
Circulation
, vol.115
, pp. 442-449
-
-
Antzelevitch, C.1
Pollevick, G.D.2
Cordeiro, J.M.3
Casis, O.4
Sanguinetti, M.C.5
-
81
-
-
84655160739
-
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)
-
Templin C, Ghadri JR, Rougier JS, Baumer A, Kaplan V, et al. (2011) Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6). European heart journal 32: 1077-88.
-
(2011)
European Heart Journal
, vol.32
, pp. 1077-1088
-
-
Templin, C.1
Ghadri, J.R.2
Rougier, J.S.3
Baumer, A.4
Kaplan, V.5
-
82
-
-
33646021938
-
CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension
-
Bremer T, Man A, Kask K, Diamond C, (2006) CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension. Pharmacogenomics 7: 271-9.
-
(2006)
Pharmacogenomics
, vol.7
, pp. 271-279
-
-
Bremer, T.1
Man, A.2
Kask, K.3
Diamond, C.4
-
83
-
-
65649121868
-
Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers
-
Kamide K, Yang J, Matayoshi T, Takiuchi S, Horio T, et al. (2009) Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers. Circulation journal: official journal of the Japanese Circulation Society 73: 732-40.
-
(2009)
Circulation Journal: Official Journal of the Japanese Circulation Society
, vol.73
, pp. 732-740
-
-
Kamide, K.1
Yang, J.2
Matayoshi, T.3
Takiuchi, S.4
Horio, T.5
-
84
-
-
67349208839
-
Genome-wide association study of blood pressure and hypertension
-
Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, et al. (2009) Genome-wide association study of blood pressure and hypertension. Nature genetics 41: 677-87.
-
(2009)
Nature Genetics
, vol.41
, pp. 677-687
-
-
Levy, D.1
Ehret, G.B.2
Rice, K.3
Verwoert, G.C.4
Launer, L.J.5
-
85
-
-
0023710312
-
Cholesterol and lipids in the risk of coronary artery disease-the Framingham Heart Study
-
Castelli WP, (1988) Cholesterol and lipids in the risk of coronary artery disease-the Framingham Heart Study. The Canadian journal of cardiology 4 Suppl A: 5A-10A.
-
(1988)
The Canadian Journal of Cardiology
, vol.4
, Issue.SUPPL.
-
-
Castelli, W.P.1
-
86
-
-
0024293497
-
Electron microscopy and structural model of human fibronectin receptor
-
Nermut MV, Green NM, Eason P, Yamada SS, Yamada KM, (1988) Electron microscopy and structural model of human fibronectin receptor. The EMBO journal 7: 4093-9.
-
(1988)
The EMBO Journal
, vol.7
, pp. 4093-4099
-
-
Nermut, M.V.1
Green, N.M.2
Eason, P.3
Yamada, S.S.4
Yamada, K.M.5
-
87
-
-
77953230966
-
Blood pressure and hypertension are associated with 7 loci in the Japanese population
-
Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, et al. (2010) Blood pressure and hypertension are associated with 7 loci in the Japanese population. Circulation 121: 2302-9.
-
(2010)
Circulation
, vol.121
, pp. 2302-2309
-
-
Takeuchi, F.1
Isono, M.2
Katsuya, T.3
Yamamoto, K.4
Yokota, M.5
-
88
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, et al. (2002) A central role for JNK in obesity and insulin resistance. Nature 420: 333-6.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Görgün, C.Z.4
Uysal, K.T.5
-
90
-
-
59649099369
-
Multiple genetic variants along candidate pathways inuence plasma high-density lipoprotein cholesterol concentrations
-
Lu Y, Dollé MET, Imholz S, van 't Slot R, Verschuren WMM, et al. (2008) Multiple genetic variants along candidate pathways inuence plasma high-density lipoprotein cholesterol concentrations. Journal of lipid research 49: 2582-9.
-
(2008)
Journal of Lipid Research
, vol.49
, pp. 2582-2589
-
-
Lu, Y.1
Dollé, M.E.T.2
Imholz, S.3
van 't Slot, R.4
Verschuren, W.M.M.5
-
91
-
-
50449089356
-
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
-
Ferreira MAR, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, et al. (2008) Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nature genetics 40: 1056-8.
-
(2008)
Nature Genetics
, vol.40
, pp. 1056-1058
-
-
Ferreira, M.A.R.1
O'Donovan, M.C.2
Meng, Y.A.3
Jones, I.R.4
Ruderfer, D.M.5
-
92
-
-
60549085927
-
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
-
Moskvina V, Craddock N, Holmans P, Nikolov I, Pahwa JS, et al. (2009) Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Molecular psychiatry 14: 252-60.
-
(2009)
Molecular Psychiatry
, vol.14
, pp. 252-260
-
-
Moskvina, V.1
Craddock, N.2
Holmans, P.3
Nikolov, I.4
Pahwa, J.S.5
-
93
-
-
77954510735
-
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia
-
Green EK, Grozeva D, Jones I, Jones L, Kirov G, et al. (2010) The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Molecular psychiatry 15: 1016-22.
-
(2010)
Molecular Psychiatry
, vol.15
, pp. 1016-1022
-
-
Green, E.K.1
Grozeva, D.2
Jones, I.3
Jones, L.4
Kirov, G.5
-
94
-
-
65949124249
-
Genomewide association studies-illuminating biologic pathways
-
Hirschhorn JN, (2009) Genomewide association studies-illuminating biologic pathways. The New England journal of medicine 360: 1699-701.
-
(2009)
The New England Journal of Medicine
, vol.360
, pp. 1699-1701
-
-
Hirschhorn, J.N.1
-
95
-
-
70149101114
-
Using genome-wide pathway analysis to unravel the etiology of complex diseases
-
Elbers CC, van Eijk KR, Franke L, Mulder F, van der Schouw YT, et al. (2009) Using genome-wide pathway analysis to unravel the etiology of complex diseases. Genetic epidemiology 33: 419-31.
-
(2009)
Genetic Epidemiology
, vol.33
, pp. 419-431
-
-
Elbers, C.C.1
van Eijk, K.R.2
Franke, L.3
Mulder, F.4
van der Schouw, Y.T.5
-
96
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, et al. (2012) An integrated encyclopedia of DNA elements in the human genome. Nature 489: 57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
Birney, E.2
Dunham, I.3
Green, E.D.4
Gunter, C.5
-
97
-
-
84865800494
-
The long-range interaction landscape of gene promoters
-
Sanyal A, Lajoie BR, Jain G, Dekker J, (2012) The long-range interaction landscape of gene promoters. Nature 489: 109-113.
-
(2012)
Nature
, vol.489
, pp. 109-113
-
-
Sanyal, A.1
Lajoie, B.R.2
Jain, G.3
Dekker, J.4
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