Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression

NeuroImage

Volumn 63, Issue 3, 2012, Pages 1681-1694

  Silver, Matt ^a   Janousova, Eva ^a,b   Hua, Xue ^c   Thompson, Paul M ^c   Montana, Giovanni ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b MASARYK UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Atrophy; Gene pathways; Imaging genetics; Sparse regression

Indexed keywords

AMYLOID BETA PROTEIN; INSULIN;

ACACA GENE; ACTN1 GENE; ADCY2 GENE; ALZHEIMER DISEASE; APOE GENE; ARTICLE; BRAIN REGION; COMPUTER PROGRAM; CONTROLLED STUDY; CR1 GENE; ENDOPHENOTYPE; FOCAL ADHESION; GENE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE INTERACTION; GENE MAPPING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DATABASE; GNAI1 GENE; HIPPOCAMPUS; HUMAN; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PHENOTYPE; PIK3CG GENE; PIK3R3 GENE; PRIORITY JOURNAL; PRKCA GENE; PRKCB GENE; QUANTITATIVE TRAIT; REGRESSION ANALYSIS; SENILE PLAQUE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOOTH MUSCLE CONTRACTION; THREE DIMENSIONAL IMAGING; TOMM40 GENE; VASCULAR SMOOTH MUSCLE; VOXEL BASED MORPHOMETRY;

AGED; ALZHEIMER DISEASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SIGNAL TRANSDUCTION;

EID: 84867345007     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2012.08.002     Document Type: Article

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