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Volumn 20, Issue 17, 2011, Pages 3494-3506

Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC STABILITY; GENETIC SUSCEPTIBILITY; HUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION;

EID: 80051683088     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr248     Document Type: Article
Times cited : (59)

References (47)
  • 1
    • 66149094262 scopus 로고    scopus 로고
    • The Immunopathogenesis of Rheumatoid Arthritis
    • Imboden, J.B. (2009) The Immunopathogenesis of Rheumatoid Arthritis. Annu. Rev. Pathol. Mech. Dis., 4, 417-434.
    • (2009) Annu. Rev. Pathol. Mech. Dis. , vol.4 , pp. 417-434
    • Imboden, J.B.1
  • 2
    • 35648988128 scopus 로고    scopus 로고
    • New therapies for treatment of rheumatoid arthritis
    • Smolen, J.S., Aletaha, D., Koeller, M., Weisman, M.H. and Emery, P. (2007) New therapies for treatment of rheumatoid arthritis. Lancet, 370, 1861-1874.
    • (2007) Lancet , vol.370 , pp. 1861-1874
    • Smolen, J.S.1    Aletaha, D.2    Koeller, M.3    Weisman, M.H.4    Emery, P.5
  • 3
    • 34249720998 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of rheumatoid arthritis
    • McInnes, I.B. and Schett, G. (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nat. Rev. Immunol., 7, 429-442.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 429-442
    • McInnes, I.B.1    Schett, G.2
  • 4
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • The Wellcome Trust Case Control Consortium
    • The Wellcome Trust Case Control Consortium. (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447, 661-78.
    • (2007) Nature , vol.447 , pp. 661-678
  • 12
    • 0344033602 scopus 로고    scopus 로고
    • Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power
    • Chapman, J.M., Cooper, J.D., Todd, J.A. and Clayton, D.G. (2003) Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power. Hum. Heredity, 56, 18-31.
    • (2003) Hum. Heredity , vol.56 , pp. 18-31
    • Chapman, J.M.1    Cooper, J.D.2    Todd, J.A.3    Clayton, D.G.4
  • 13
    • 51749119425 scopus 로고    scopus 로고
    • Analysis of multiple SNPs in a candidate gene or region
    • Chapman, J. and Whittaker, J. (2008) Analysis of multiple SNPs in a candidate gene or region. Genet. Epidemiol., 32, 560-566.
    • (2008) Genet. Epidemiol. , vol.32 , pp. 560-566
    • Chapman, J.1    Whittaker, J.2
  • 14
    • 33846565755 scopus 로고    scopus 로고
    • Improved power by use of a weighted score test for linkage disequilibrium mapping
    • Wang, T. and Elston, R.C. (2007) Improved power by use of a weighted score test for linkage disequilibrium mapping. Am. J. Hum. Genet., 80, 353-360.
    • (2007) Am. J. Hum. Genet. , vol.80 , pp. 353-360
    • Wang, T.1    Elston, R.C.2
  • 15
    • 77949776227 scopus 로고    scopus 로고
    • Association tests using kernel-based measures of multi-locus genotype similarity between individuals
    • Indranil, M., Eleanor, F., Daniel, E.W. and Anbupalam, T. (2009) Association tests using kernel-based measures of multi-locus genotype similarity between individuals. Genet. Epidemiol., 34, 213-221.
    • (2009) Genet. Epidemiol. , vol.34 , pp. 213-221
    • Indranil, M.1    Eleanor, F.2    Daniel, E.W.3    Anbupalam, T.4
  • 16
    • 39649125434 scopus 로고    scopus 로고
    • A principal components regression approach to multilocus genetic association studies
    • Wang, K. and Abbott, D. (2008) A principal components regression approach to multilocus genetic association studies. Genet. Epidemiol., 32, 108-118.
    • (2008) Genet. Epidemiol. , vol.32 , pp. 108-118
    • Wang, K.1    Abbott, D.2
  • 17
    • 34447315844 scopus 로고    scopus 로고
    • Testing association between disease and multiple SNPs in a candidate gene
    • Gauderman, W.J., Murcray, C., Gilliland, F. and Conti, D.V. (2007) Testing association between disease and multiple SNPs in a candidate gene. Genet. Epidemiol., 31, 383-395.
    • (2007) Genet. Epidemiol. , vol.31 , pp. 383-395
    • Gauderman, W.J.1    Murcray, C.2    Gilliland, F.3    Conti, D.V.4
  • 19
    • 33750211858 scopus 로고    scopus 로고
    • A gene-centric approach to genome-wide association studies
    • Jorgenson, E. and Witte, J.S. (2006) A gene-centric approach to genome-wide association studies. Nat. Rev. Genet., 7, 885-891.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 885-891
    • Jorgenson, E.1    Witte, J.S.2
  • 20
    • 60149093075 scopus 로고    scopus 로고
    • ATOM: a powerful gene-based association test by combining optimally weighted markers
    • Li, M.Y., Wang, K., Grant, S.F.A., Hakonarson, H. and Li, C. (2009) ATOM: a powerful gene-based association test by combining optimally weighted markers. Bioinformatics, 25, 497-503.
    • (2009) Bioinformatics , vol.25 , pp. 497-503
    • Li, M.Y.1    Wang, K.2    Grant, S.F.A.3    Hakonarson, H.4    Li, C.5
  • 21
    • 48249096806 scopus 로고    scopus 로고
    • Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies
    • Hoggart, C.J., Whittaker, J.C., De Iorio, M. and Balding, D.J. (2008) Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS Genet., 4, e1000130.
    • (2008) PLoS Genet. , vol.4
    • Hoggart, C.J.1    Whittaker, J.C.2    De Iorio, M.3    Balding, D.J.4
  • 22
    • 70149101114 scopus 로고    scopus 로고
    • Using genome-wide pathway analysis to unravel the etiology of complex diseases
    • Elbers, C. (2009) Using genome-wide pathway analysis to unravel the etiology of complex diseases. Genet. Epidemiol., 33, 419-431.
    • (2009) Genet. Epidemiol. , vol.33 , pp. 419-431
    • Elbers, C.1
  • 24
    • 53649098737 scopus 로고    scopus 로고
    • Pathway analysis of seven common diseases assessed by genome-wide association
    • Torkamani, A., Topol, E.J. and Schork, N.J. (2008) Pathway analysis of seven common diseases assessed by genome-wide association. Genomics, 92, 265-272.
    • (2008) Genomics , vol.92 , pp. 265-272
    • Torkamani, A.1    Topol, E.J.2    Schork, N.J.3
  • 25
    • 73149103718 scopus 로고    scopus 로고
    • Prioritizing GWAS results: a review of statistical methods and recommendations for their application
    • Cantor, R.M., Lange, K. and Sinsheimer, J.S. (2010) Prioritizing GWAS results: a review of statistical methods and recommendations for their application. Am. J. Hum. Genet., 86, 6-22.
    • (2010) Am. J. Hum. Genet. , vol.86 , pp. 6-22
    • Cantor, R.M.1    Lange, K.2    Sinsheimer, J.S.3
  • 26
    • 65549084289 scopus 로고    scopus 로고
    • Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
    • Baranzini, S. (2009) Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum. Mol. Genet., 18, 2078-2090.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 2078-2090
    • Baranzini, S.1
  • 28
    • 77953920566 scopus 로고    scopus 로고
    • Pathway analysis comparison using Crohn's disease genome wide association studies
    • Ballard, D., Abraham, C., Cho, J. and Zhao, H. (2010) Pathway analysis comparison using Crohn's disease genome wide association studies. BMC Med. Genom., 3, 25.
    • (2010) BMC Med. Genom. , vol.3 , pp. 25
    • Ballard, D.1    Abraham, C.2    Cho, J.3    Zhao, H.4
  • 31
    • 60849139395 scopus 로고    scopus 로고
    • GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
    • Eden, E., Navon, R., Steinfeld, I., Lipson, D. and Yakhini, Z. (2009) GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists. BMC Bioinform., 10, 48.
    • (2009) BMC Bioinform. , vol.10 , pp. 48
    • Eden, E.1    Navon, R.2    Steinfeld, I.3    Lipson, D.4    Yakhini, Z.5
  • 32
    • 38149018650 scopus 로고    scopus 로고
    • Diacylglycerol kinases: at the hub of cell signalling
    • Merida, I., Avila-Flores, A. and Merino, E. (2008) Diacylglycerol kinases: at the hub of cell signalling. Biochem. J., 409, 1-18.
    • (2008) Biochem. J. , vol.409 , pp. 1-18
    • Merida, I.1    Avila-Flores, A.2    Merino, E.3
  • 35
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • Clapham, D.E. (2007) Calcium signaling. Cell, 131, 1047-1058.
    • (2007) Cell , vol.131 , pp. 1047-1058
    • Clapham, D.E.1
  • 36
    • 33644524741 scopus 로고    scopus 로고
    • Cell-signalling dynamics in time and space
    • Kholodenko, B.N. (2006) Cell-signalling dynamics in time and space. Nat. Rev. Mol. Cell Biol., 7, 165-176.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 165-176
    • Kholodenko, B.N.1
  • 37
    • 35848943698 scopus 로고    scopus 로고
    • Mitogenic signaling pathways induced by G protein-coupled receptors
    • Rozengurt, E. (2007) Mitogenic signaling pathways induced by G protein-coupled receptors. J. Cell. Physiol., 213, 589-602.
    • (2007) J. Cell. Physiol. , vol.213 , pp. 589-602
    • Rozengurt, E.1
  • 38
    • 78549251736 scopus 로고    scopus 로고
    • Analysing biological pathways in genome-wide association studies
    • Wang, K., Li, M. and Hakonarson, H. (2010) Analysing biological pathways in genome-wide association studies. Nat. Rev. Genet., 11, 843-854.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 843-854
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 40
    • 0017650744 scopus 로고
    • Synthesis of collagen by chondrocytes in suspension culture - modulation by calcium, 3′-5′-cyclic amp, and prostaglandins - (Arthritis Protein Synthesis Invitro)
    • Deshmukh, K. and Sawyer, B.D. (1977) Synthesis of collagen by chondrocytes in suspension culture - modulation by calcium, 3′-5′-cyclic amp, and prostaglandins - (Arthritis Protein Synthesis Invitro). Proc. Natl Acad. Sci. USA, 74, 3864-3868.
    • (1977) Proc. Natl Acad. Sci. USA , vol.74 , pp. 3864-3868
    • Deshmukh, K.1    Sawyer, B.D.2
  • 41
    • 0028978114 scopus 로고
    • Altered T-Lymphocyte Signaling in Rheumatoid-Arthritis
    • Allen, M.E., Young, S.P., Michell, R.H. and Bacon, P.A. (1995) Altered T-Lymphocyte Signaling in Rheumatoid-Arthritis. Eur. J. Immunol., 25, 1547-1554.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1547-1554
    • Allen, M.E.1    Young, S.P.2    Michell, R.H.3    Bacon, P.A.4
  • 42
    • 0034130633 scopus 로고    scopus 로고
    • Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors
    • Souness, J.E., Aldous, D. and Sargent, C. (2000) Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors. Immunopharmacology, 47, 127-162.
    • (2000) Immunopharmacology , vol.47 , pp. 127-162
    • Souness, J.E.1    Aldous, D.2    Sargent, C.3
  • 44
    • 77953123145 scopus 로고    scopus 로고
    • Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data
    • Chen, L.S., Hutter, C.M., Potter, J.D., Liu, Y., Prentice, R.L., Peters, U. and Hsu, L. (2010) Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data. Am. J. Hum. Gene., 86, 860-871.
    • (2010) Am. J. Hum. Gene. , vol.86 , pp. 860-871
    • Chen, L.S.1    Hutter, C.M.2    Potter, J.D.3    Liu, Y.4    Prentice, R.L.5    Peters, U.6    Hsu, L.7
  • 46
    • 2142773942 scopus 로고    scopus 로고
    • The fine-scale structure of recombination rate variation in the human genome
    • McVean, G.A.T., Myers, S.R., Hunt, S., Deloukas, P., Bentley, D.R. and Donnelly, P. (2004) The fine-scale structure of recombination rate variation in the human genome. Science, 304, 581-584.
    • (2004) Science , vol.304 , pp. 581-584
    • McVean, G.A.T.1    Myers, S.R.2    Hunt, S.3    Deloukas, P.4    Bentley, D.R.5    Donnelly, P.6
  • 47
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • WTCCC
    • WTCCC. (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447, 661-678.
    • (2007) Nature , vol.447 , pp. 661-678


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