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Volumn 42, Issue 4, 2013, Pages 697-719

Advanced Glycation Endproducts in Diabetes and Diabetic Complications

Author keywords

Advanced glycation endproduct; Diabetes; Insulin resistance; Metabolism

Indexed keywords

3 DEOXYGLUCOSONE; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; AMINOGUANIDINE; BENFOTIAMINE; GLYOXAL, 3 DEOXYGLUCOSONE; GLYOXALASE; GLYOXALASE 1; HEMOGLOBIN A1C; LACTOYLGLUTATHIONE LYASE; METFORMIN; PYRIDOXAMINE; SIRTUIN 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

EID: 84888091341     PISSN: 08898529     EISSN: 15584410     Source Type: Journal    
DOI: 10.1016/j.ecl.2013.07.005     Document Type: Review
Times cited : (131)

References (90)
  • 1
    • 3242664216 scopus 로고    scopus 로고
    • Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure?
    • Ward R.A., McLeish K.R. Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure?. Nephrol Dial Transplant 2004, 19(7):1702-1707.
    • (2004) Nephrol Dial Transplant , vol.19 , Issue.7 , pp. 1702-1707
    • Ward, R.A.1    McLeish, K.R.2
  • 2
    • 82855177408 scopus 로고    scopus 로고
    • Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose
    • Kim K.M., Kim Y.S., Jung D.H., et al. Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose. Exp Cell Res 2012, 318(2):152-159.
    • (2012) Exp Cell Res , vol.318 , Issue.2 , pp. 152-159
    • Kim, K.M.1    Kim, Y.S.2    Jung, D.H.3
  • 3
    • 70449131003 scopus 로고    scopus 로고
    • Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1
    • Vlassara H., Cai W., Goodman S., et al. Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1. JClin Endocrinol Metab 2009, 94(11):4483-4491.
    • (2009) JClin Endocrinol Metab , vol.94 , Issue.11 , pp. 4483-4491
    • Vlassara, H.1    Cai, W.2    Goodman, S.3
  • 4
    • 0037180567 scopus 로고    scopus 로고
    • Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy
    • Vlassara H., Cai W., Crandall J., et al. Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy. Proc Natl Acad Sci USA 2002, 99(24):15596-15601.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.24 , pp. 15596-15601
    • Vlassara, H.1    Cai, W.2    Crandall, J.3
  • 5
    • 0030992848 scopus 로고    scopus 로고
    • Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy
    • Koschinsky T., He C.J., Mitsuhashi T., et al. Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy. Proc Natl Acad Sci USA 1997, 94(12):6474-6479.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.12 , pp. 6474-6479
    • Koschinsky, T.1    He, C.J.2    Mitsuhashi, T.3
  • 6
    • 0345711536 scopus 로고    scopus 로고
    • Dietary glycotoxins: inhibition of reactive products by aminoguanidine facilitates renal clearance and reduces tissue sequestration
    • He C., Sabol J., Mitsuhashi T., et al. Dietary glycotoxins: inhibition of reactive products by aminoguanidine facilitates renal clearance and reduces tissue sequestration. Diabetes 1999, 48(6):1308-1315.
    • (1999) Diabetes , vol.48 , Issue.6 , pp. 1308-1315
    • He, C.1    Sabol, J.2    Mitsuhashi, T.3
  • 7
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414(6865):813-820.
    • (2001) Nature , vol.414 , Issue.6865 , pp. 813-820
    • Brownlee, M.1
  • 8
    • 0002602893 scopus 로고
    • Nonenzymatic glycosylation: role in the pathogenesis of diabetic complications
    • Vlassara H., Brownlee M., Cerami A. Nonenzymatic glycosylation: role in the pathogenesis of diabetic complications. Clin Chem 1986, 32(Suppl 10):B37-B41.
    • (1986) Clin Chem , vol.32 , Issue.SUPPL. 10
    • Vlassara, H.1    Brownlee, M.2    Cerami, A.3
  • 9
    • 48749126012 scopus 로고    scopus 로고
    • Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan
    • Cai W., He J.C., Zhu L., et al. Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan. Am J Pathol 2008, 173(2):327-336.
    • (2008) Am J Pathol , vol.173 , Issue.2 , pp. 327-336
    • Cai, W.1    He, J.C.2    Zhu, L.3
  • 10
    • 84887958895 scopus 로고    scopus 로고
    • Mortality trends in patients with and without diabetes in Ontario, Canada and the UK from 1996 to 2009: a population-based study
    • [Epub ahead of print]
    • Lind M., Garcia-Rodriguez L.A., Booth G.L., et al. Mortality trends in patients with and without diabetes in Ontario, Canada and the UK from 1996 to 2009: a population-based study. Diabetologia 2013, [Epub ahead of print].
    • (2013) Diabetologia
    • Lind, M.1    Garcia-Rodriguez, L.A.2    Booth, G.L.3
  • 11
    • 84878238782 scopus 로고    scopus 로고
    • The TODAY study: an NIH perspective on its implications for research
    • Linder B.L., Fradkin J.E., Rodgers G.P. The TODAY study: an NIH perspective on its implications for research. Diabetes Care 2013, 36(6):1775-1776.
    • (2013) Diabetes Care , vol.36 , Issue.6 , pp. 1775-1776
    • Linder, B.L.1    Fradkin, J.E.2    Rodgers, G.P.3
  • 12
    • 80052059557 scopus 로고    scopus 로고
    • AGE restriction in diabetes mellitus: a paradigm shift
    • Vlassara H., Striker G.E. AGE restriction in diabetes mellitus: a paradigm shift. Nat Rev Endocrinol 2011, 7(9):526-539.
    • (2011) Nat Rev Endocrinol , vol.7 , Issue.9 , pp. 526-539
    • Vlassara, H.1    Striker, G.E.2
  • 13
    • 66649125230 scopus 로고    scopus 로고
    • Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis
    • Zhao Z., Zhao C., Zhang X.H., et al. Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis. Endocrinology 2009, 150(6):2569-2576.
    • (2009) Endocrinology , vol.150 , Issue.6 , pp. 2569-2576
    • Zhao, Z.1    Zhao, C.2    Zhang, X.H.3
  • 14
    • 84875431011 scopus 로고    scopus 로고
    • Adult-onset autoimmune diabetes in Europe is prevalent with a broad clinical phenotype: Action LADA 7
    • Hawa M.I., Kolb H., Schloot N., et al. Adult-onset autoimmune diabetes in Europe is prevalent with a broad clinical phenotype: Action LADA 7. Diabetes Care 2013, 36(4):908-913.
    • (2013) Diabetes Care , vol.36 , Issue.4 , pp. 908-913
    • Hawa, M.I.1    Kolb, H.2    Schloot, N.3
  • 15
    • 80052142793 scopus 로고    scopus 로고
    • Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: potential role of AGER1 and SIRT1
    • Uribarri J., Cai W., Ramdas M., et al. Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: potential role of AGER1 and SIRT1. Diabetes Care 2011, 34(7):1610-1616.
    • (2011) Diabetes Care , vol.34 , Issue.7 , pp. 1610-1616
    • Uribarri, J.1    Cai, W.2    Ramdas, M.3
  • 16
    • 33845776585 scopus 로고    scopus 로고
    • Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711)
    • Peppa M., Brem H., Cai W., et al. Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711). Am J Nephrol 2006, 26(5):430-436.
    • (2006) Am J Nephrol , vol.26 , Issue.5 , pp. 430-436
    • Peppa, M.1    Brem, H.2    Cai, W.3
  • 17
    • 84878465280 scopus 로고    scopus 로고
    • Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
    • Everard A., Belzer C., Geurts L., et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci USA 2013, 110(22):9066-9071.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.22 , pp. 9066-9071
    • Everard, A.1    Belzer, C.2    Geurts, L.3
  • 18
    • 84878709716 scopus 로고    scopus 로고
    • Gut metagenome in European women with normal, impaired and diabetic glucose control
    • Karlsson F.H., Tremaroli V., Nookaew I., et al. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 2013, 498(7452):99-103.
    • (2013) Nature , vol.498 , Issue.7452 , pp. 99-103
    • Karlsson, F.H.1    Tremaroli, V.2    Nookaew, I.3
  • 19
    • 3242700397 scopus 로고    scopus 로고
    • High levels of dietary advanced glycation end products transform low-density lipoprotein into a potent redox-sensitive mitogen-activated protein kinase stimulant in diabetic patients
    • Cai W., He J.C., Zhu L., et al. High levels of dietary advanced glycation end products transform low-density lipoprotein into a potent redox-sensitive mitogen-activated protein kinase stimulant in diabetic patients. Circulation 2004, 110(3):285-291.
    • (2004) Circulation , vol.110 , Issue.3 , pp. 285-291
    • Cai, W.1    He, J.C.2    Zhu, L.3
  • 20
    • 0142105845 scopus 로고    scopus 로고
    • Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum
    • Staprans I., Pan X.M., Rapp J.H., et al. Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum. JLipid Res 2003, 44(4):705-715.
    • (2003) JLipid Res , vol.44 , Issue.4 , pp. 705-715
    • Staprans, I.1    Pan, X.M.2    Rapp, J.H.3
  • 21
    • 84881240163 scopus 로고    scopus 로고
    • Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation
    • Vistoli G., Maddis D., De Maddis D., et al. Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation. Free Radic Res 2013, 47(Suppl 1):3-27.
    • (2013) Free Radic Res , vol.47 , Issue.SUPPL. 1 , pp. 3-27
    • Vistoli, G.1    Maddis, D.2    De Maddis, D.3
  • 22
    • 3242700397 scopus 로고    scopus 로고
    • Dietary-AGE-modified LDL is a potent redox-sensitive MAPk stimulant in diabetic patients
    • Cai W., He C., Zhu L., et al. Dietary-AGE-modified LDL is a potent redox-sensitive MAPk stimulant in diabetic patients. Circulation 2004, 110:285-291.
    • (2004) Circulation , vol.110 , pp. 285-291
    • Cai, W.1    He, C.2    Zhu, L.3
  • 23
    • 57549113882 scopus 로고    scopus 로고
    • Advanced glycation end-product of low density lipoprotein activates the toll-like 4 receptor pathway implications for diabetic atherosclerosis
    • Hodgkinson C.P., Laxton R.C., Patel K., et al. Advanced glycation end-product of low density lipoprotein activates the toll-like 4 receptor pathway implications for diabetic atherosclerosis. Arterioscler Thromb Vasc Biol 2008, 28(12):2275-2281.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.12 , pp. 2275-2281
    • Hodgkinson, C.P.1    Laxton, R.C.2    Patel, K.3
  • 24
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi H., Kokoeva M.V., Inouye K., et al. TLR4 links innate immunity and fatty acid-induced insulin resistance. JClin Invest 2006, 116(11):3015-3025.
    • (2006) JClin Invest , vol.116 , Issue.11 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3
  • 25
    • 0347419281 scopus 로고    scopus 로고
    • Glyoxalase I-structure, function and a critical role in the enzymatic defence against glycation
    • Thornalley P.J. Glyoxalase I-structure, function and a critical role in the enzymatic defence against glycation. Biochem Soc Trans 2003, 31(Pt 6):1343-1348.
    • (2003) Biochem Soc Trans , vol.31 , Issue.PART 6 , pp. 1343-1348
    • Thornalley, P.J.1
  • 26
    • 0035668462 scopus 로고    scopus 로고
    • The AGE-receptor in the pathogenesis of diabetic complications
    • Vlassara H. The AGE-receptor in the pathogenesis of diabetic complications. Diabetes Metab Res Rev 2001, 17(6):436-443.
    • (2001) Diabetes Metab Res Rev , vol.17 , Issue.6 , pp. 436-443
    • Vlassara, H.1
  • 27
    • 0028286374 scopus 로고
    • Reactive glycosylation endproducts in diabetic uraemia and treatment of renal failure
    • Makita Z., Bucala R., Rayfield E.J., et al. Reactive glycosylation endproducts in diabetic uraemia and treatment of renal failure. Lancet 1994, 343(8912):1519-1522.
    • (1994) Lancet , vol.343 , Issue.8912 , pp. 1519-1522
    • Makita, Z.1    Bucala, R.2    Rayfield, E.J.3
  • 28
    • 0025938891 scopus 로고
    • Advanced glycosylation end products in patients with diabetic nephropathy
    • Makita Z., Radoff S., Rayfield E.J., et al. Advanced glycosylation end products in patients with diabetic nephropathy. NEngl J Med 1991, 325(12):836-842.
    • (1991) NEngl J Med , vol.325 , Issue.12 , pp. 836-842
    • Makita, Z.1    Radoff, S.2    Rayfield, E.J.3
  • 29
    • 0034795140 scopus 로고    scopus 로고
    • The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
    • Schmidt A.M., Yan S.D., Yan S.F., et al. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 2001, 108(7):949-955.
    • (2001) J Clin Invest , vol.108 , Issue.7 , pp. 949-955
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3
  • 30
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414(6865):813-820.
    • (2001) Nature , vol.414 , Issue.6865 , pp. 813-820
    • Brownlee, M.1
  • 31
    • 0027184474 scopus 로고
    • Lipid advanced glycosylation: pathway for lipid oxidation invivo
    • Bucala R., Makita Z., Koschinsky T., et al. Lipid advanced glycosylation: pathway for lipid oxidation invivo. Proc Natl Acad Sci USA 1993, 90(14):6434-6438.
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.14 , pp. 6434-6438
    • Bucala, R.1    Makita, Z.2    Koschinsky, T.3
  • 32
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: a new perspective on an old paradigm
    • Baynes J.W., Thorpe S.R. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 1999, 48(1):1-9.
    • (1999) Diabetes , vol.48 , Issue.1 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 33
    • 0029923574 scopus 로고    scopus 로고
    • The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions
    • Fu M.X., Requena J.R., Jenkins A.J., et al. The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions. JBiol Chem 1996, 271(17):9982-9986.
    • (1996) JBiol Chem , vol.271 , Issue.17 , pp. 9982-9986
    • Fu, M.X.1    Requena, J.R.2    Jenkins, A.J.3
  • 34
    • 0032997958 scopus 로고    scopus 로고
    • Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial
    • Monnier V.M., Bautista O., Kenny D., et al. Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial. Diabetes 1999, 48(4):870-880.
    • (1999) Diabetes , vol.48 , Issue.4 , pp. 870-880
    • Monnier, V.M.1    Bautista, O.2    Kenny, D.3
  • 35
    • 23044432863 scopus 로고    scopus 로고
    • The absorption and metabolism of modified amino acids in processed foods
    • Finot P.A. The absorption and metabolism of modified amino acids in processed foods. JAOAC Int 2005, 88(3):894-903.
    • (2005) JAOAC Int , vol.88 , Issue.3 , pp. 894-903
    • Finot, P.A.1
  • 36
    • 0033916712 scopus 로고    scopus 로고
    • Mutagenicity of heated sugar-casein systems: effect of the Maillard reaction
    • Brands C.M., Alink G.M., van Boekel M.A., et al. Mutagenicity of heated sugar-casein systems: effect of the Maillard reaction. JAgric Food Chem 2000, 48:2271-2275.
    • (2000) JAgric Food Chem , vol.48 , pp. 2271-2275
    • Brands, C.M.1    Alink, G.M.2    van Boekel, M.A.3
  • 37
    • 33947671901 scopus 로고    scopus 로고
    • Advanced glycation endproducts: what is their relevance to diabetic complications?
    • Ahmed N., Thornalley P.J. Advanced glycation endproducts: what is their relevance to diabetic complications?. Diabetes Obes Metab 2007, 9(3):233-245.
    • (2007) Diabetes Obes Metab , vol.9 , Issue.3 , pp. 233-245
    • Ahmed, N.1    Thornalley, P.J.2
  • 38
    • 84858307371 scopus 로고    scopus 로고
    • Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
    • Xue M., Rabbani N., Momiji H., et al. Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. Biochem J 2012, 443(1):213-222.
    • (2012) Biochem J , vol.443 , Issue.1 , pp. 213-222
    • Xue, M.1    Rabbani, N.2    Momiji, H.3
  • 39
    • 0004818738 scopus 로고
    • High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules
    • Vlassara H., Brownlee M., Cerami A. High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules. Proc Natl Acad Sci USA 1985, 82(17):5588-5592.
    • (1985) Proc Natl Acad Sci USA , vol.82 , Issue.17 , pp. 5588-5592
    • Vlassara, H.1    Brownlee, M.2    Cerami, A.3
  • 40
    • 0001263746 scopus 로고    scopus 로고
    • Molecular identity and cellular distribution of advanced glycation endproduct receptors: Relationship of p60 to OST-48 and p90 to 80K-H membrane proteins
    • Li Y.M., Mitsuhashi T., Wojciechowicz D., et al. Molecular identity and cellular distribution of advanced glycation endproduct receptors: Relationship of p60 to OST-48 and p90 to 80K-H membrane proteins. Proc Natl Acad Sci USA 1996, 93(20):11047-11052.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.20 , pp. 11047-11052
    • Li, Y.M.1    Mitsuhashi, T.2    Wojciechowicz, D.3
  • 41
    • 0035293890 scopus 로고    scopus 로고
    • Presence of diabetic complications in type 1 diabetic patients correlates with low expression of mononuclear cell AGE-receptor-1 and elevated serum AGE
    • He C.J., Koschinsky T., Buenting C., et al. Presence of diabetic complications in type 1 diabetic patients correlates with low expression of mononuclear cell AGE-receptor-1 and elevated serum AGE. Mol Med 2001, 7(3):159-168.
    • (2001) Mol Med , vol.7 , Issue.3 , pp. 159-168
    • He, C.J.1    Koschinsky, T.2    Buenting, C.3
  • 42
    • 77749264564 scopus 로고    scopus 로고
    • AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease
    • Cai W., Torreggiani M., Zhu L., et al. AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease. Am J Physiol Cell Physiol 2009, 298(3):C624-C634.
    • (2009) Am J Physiol Cell Physiol , vol.298 , Issue.3
    • Cai, W.1    Torreggiani, M.2    Zhu, L.3
  • 43
    • 33748802532 scopus 로고    scopus 로고
    • Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor
    • Cai W., He J.C., Zhu L., et al. Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor. Proc Natl Acad Sci USA 2006, 103(37):13801-13806.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.37 , pp. 13801-13806
    • Cai, W.1    He, J.C.2    Zhu, L.3
  • 44
    • 73549096880 scopus 로고    scopus 로고
    • Advanced glycation end product receptor-1 transgenic mice are resistant to inflammation, oxidative stress, and post-injury intimal hyperplasia
    • Torreggiani M., Liu H., Wu J., et al. Advanced glycation end product receptor-1 transgenic mice are resistant to inflammation, oxidative stress, and post-injury intimal hyperplasia. Am J Pathol 2009, 175(4):1722-1732.
    • (2009) Am J Pathol , vol.175 , Issue.4 , pp. 1722-1732
    • Torreggiani, M.1    Liu, H.2    Wu, J.3
  • 45
    • 84862223183 scopus 로고    scopus 로고
    • Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease
    • Vlassara H., Uribarri J., Cai W., et al. Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease. Clin J Am Soc Nephrol 2012, 7(6):934-942.
    • (2012) Clin J Am Soc Nephrol , vol.7 , Issue.6 , pp. 934-942
    • Vlassara, H.1    Uribarri, J.2    Cai, W.3
  • 46
    • 51549087617 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation
    • Romero R., Espinoza J., Hassan S., et al. Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation. J Perinat Med 2008, 36(5):388-398.
    • (2008) J Perinat Med , vol.36 , Issue.5 , pp. 388-398
    • Romero, R.1    Espinoza, J.2    Hassan, S.3
  • 47
    • 38349179648 scopus 로고    scopus 로고
    • Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging
    • Yan S.F., D'Agati V., Schmidt A.M., et al. Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging. Curr Mol Med 2007, 7(8):699-710.
    • (2007) Curr Mol Med , vol.7 , Issue.8 , pp. 699-710
    • Yan, S.F.1    D'Agati, V.2    Schmidt, A.M.3
  • 48
    • 34447343125 scopus 로고    scopus 로고
    • Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression
    • Cai W., He J.C., Zhu L., et al. Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression. Am J Pathol 2007, 170(6):1893-1902.
    • (2007) Am J Pathol , vol.170 , Issue.6 , pp. 1893-1902
    • Cai, W.1    He, J.C.2    Zhu, L.3
  • 49
    • 0029366113 scopus 로고
    • Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex
    • Vlassara H., Li Y.M., Imani F., et al. Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex. Mol Med 1995, 1(6):634-646.
    • (1995) Mol Med , vol.1 , Issue.6 , pp. 634-646
    • Vlassara, H.1    Li, Y.M.2    Imani, F.3
  • 50
    • 0036897063 scopus 로고    scopus 로고
    • The rise of childhood type 1 diabetes in the 20th century
    • Gale E.A. The rise of childhood type 1 diabetes in the 20th century. Diabetes 2002, 51(12):3353-3361.
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3353-3361
    • Gale, E.A.1
  • 51
    • 84860575854 scopus 로고    scopus 로고
    • Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study
    • Beyan H., Riese H., Hawa M.I., et al. Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study. Diabetes 2012, 61(5):1192-1198.
    • (2012) Diabetes , vol.61 , Issue.5 , pp. 1192-1198
    • Beyan, H.1    Riese, H.2    Hawa, M.I.3
  • 52
    • 84866839740 scopus 로고    scopus 로고
    • Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1
    • Cai W., Ramdas M., Zhu L., et al. Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1. Proc Natl Acad Sci USA 2012, 109(39):15888-15893.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.39 , pp. 15888-15893
    • Cai, W.1    Ramdas, M.2    Zhu, L.3
  • 53
    • 69449106304 scopus 로고    scopus 로고
    • SIRT1 and insulin resistance
    • Liang F., Kume S., Koya D. SIRT1 and insulin resistance. Nat Rev Endocrinol 2009, 5(7):367-373.
    • (2009) Nat Rev Endocrinol , vol.5 , Issue.7 , pp. 367-373
    • Liang, F.1    Kume, S.2    Koya, D.3
  • 54
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky J.M., Glass C.K. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 2010, 72:219-246.
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 55
    • 77956989586 scopus 로고    scopus 로고
    • Advanced glycation end products as biomarkers and gerontotoxins - a basis to explore methylglyoxal-lowering agents for Alzheimer's disease?
    • Krautwald M., Munch G. Advanced glycation end products as biomarkers and gerontotoxins - a basis to explore methylglyoxal-lowering agents for Alzheimer's disease?. Exp Gerontol 2010, 45(10):744-751.
    • (2010) Exp Gerontol , vol.45 , Issue.10 , pp. 744-751
    • Krautwald, M.1    Munch, G.2
  • 56
    • 84873817577 scopus 로고    scopus 로고
    • Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults
    • Willette A.A., Xu G., Johnson S.C., et al. Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults. Diabetes Care 2013, 36(2):443-449.
    • (2013) Diabetes Care , vol.36 , Issue.2 , pp. 443-449
    • Willette, A.A.1    Xu, G.2    Johnson, S.C.3
  • 57
    • 84855887867 scopus 로고    scopus 로고
    • Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals
    • Beeri M.S., Moshier E., Schmeidler J., et al. Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals. Mech Ageing Dev 2011, 132(11-12):583-587.
    • (2011) Mech Ageing Dev , vol.132 , Issue.11-12 , pp. 583-587
    • Beeri, M.S.1    Moshier, E.2    Schmeidler, J.3
  • 58
    • 83455179184 scopus 로고    scopus 로고
    • Role of the glyoxalase system in astrocyte-mediated neuroprotection
    • Belanger M., Yang J., Petit J.M., et al. Role of the glyoxalase system in astrocyte-mediated neuroprotection. JNeurosci 2011, 31(50):18338-18352.
    • (2011) JNeurosci , vol.31 , Issue.50 , pp. 18338-18352
    • Belanger, M.1    Yang, J.2    Petit, J.M.3
  • 59
    • 84870296895 scopus 로고    scopus 로고
    • Acute carbonyl stress induces occludin glycation and brain microvascular endothelial barrier dysfunction: role for glutathione-dependent metabolism of methylglyoxal
    • Li W., Maloney R.E., Circu M.L., et al. Acute carbonyl stress induces occludin glycation and brain microvascular endothelial barrier dysfunction: role for glutathione-dependent metabolism of methylglyoxal. Free Radic Biol Med 2013, 54:51-61.
    • (2013) Free Radic Biol Med , vol.54 , pp. 51-61
    • Li, W.1    Maloney, R.E.2    Circu, M.L.3
  • 60
    • 0021186534 scopus 로고
    • Accumulation of diabetic rat peripheral nerve myelin by macrophages increases with the presence of advanced glycosylation endproducts
    • Vlassara H., Brownlee M., Cerami A. Accumulation of diabetic rat peripheral nerve myelin by macrophages increases with the presence of advanced glycosylation endproducts. JExp Med 1984, 160(1):197-207.
    • (1984) JExp Med , vol.160 , Issue.1 , pp. 197-207
    • Vlassara, H.1    Brownlee, M.2    Cerami, A.3
  • 61
    • 84872718256 scopus 로고    scopus 로고
    • Estrogen and the male hippocampus: genetic variation in the aromatase gene predicting serum estrogen is associated with hippocampal gray matter volume in men
    • Bayer J., Rune G., Kutsche K., et al. Estrogen and the male hippocampus: genetic variation in the aromatase gene predicting serum estrogen is associated with hippocampal gray matter volume in men. Hippocampus 2013, 23(2):117-121.
    • (2013) Hippocampus , vol.23 , Issue.2 , pp. 117-121
    • Bayer, J.1    Rune, G.2    Kutsche, K.3
  • 62
    • 84942303190 scopus 로고    scopus 로고
    • Aromatase expression in cultured fetal sheep astrocytes after nitrosative/oxidative damage
    • Lepore G., Gadau S., Peruffo A., et al. Aromatase expression in cultured fetal sheep astrocytes after nitrosative/oxidative damage. Cell Tissue Res 2011, 344(3):407-413.
    • (2011) Cell Tissue Res , vol.344 , Issue.3 , pp. 407-413
    • Lepore, G.1    Gadau, S.2    Peruffo, A.3
  • 63
    • 0035876966 scopus 로고    scopus 로고
    • Brain aromatase is neuroprotective
    • Azcoitia I., Sierra A., Veiga S., et al. Brain aromatase is neuroprotective. JNeurobiol 2001, 47(4):318-329.
    • (2001) JNeurobiol , vol.47 , Issue.4 , pp. 318-329
    • Azcoitia, I.1    Sierra, A.2    Veiga, S.3
  • 64
    • 79952763784 scopus 로고    scopus 로고
    • Estrogens and progression of diabetic kidney damage
    • Doublier S., Lupia E., Catanuto P., et al. Estrogens and progression of diabetic kidney damage. Curr Diabetes Rev 2011, 7(1):28-34.
    • (2011) Curr Diabetes Rev , vol.7 , Issue.1 , pp. 28-34
    • Doublier, S.1    Lupia, E.2    Catanuto, P.3
  • 65
    • 0027970304 scopus 로고
    • Advanced glycation end products induce glomerular sclerosis and albuminuria in normal rats
    • Vlassara H., Striker L.J., Teichberg S., et al. Advanced glycation end products induce glomerular sclerosis and albuminuria in normal rats. Proc Natl Acad Sci USA 1994, 91(24):11704-11708.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.24 , pp. 11704-11708
    • Vlassara, H.1    Striker, L.J.2    Teichberg, S.3
  • 66
    • 84878912696 scopus 로고    scopus 로고
    • TGF-beta induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy
    • Kato M., Dang V., Wang M., et al. TGF-beta induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy. Sci Signal 2013, 6(278):ra43.
    • (2013) Sci Signal , vol.6 , Issue.278
    • Kato, M.1    Dang, V.2    Wang, M.3
  • 67
    • 34447128666 scopus 로고    scopus 로고
    • Elevated cystatin concentration and progression to pre-diabetes
    • Richard P., Donahue R.P., Stranges S., et al. Elevated cystatin concentration and progression to pre-diabetes. Diabetes Care 2007, 30:1724-1729.
    • (2007) Diabetes Care , vol.30 , pp. 1724-1729
    • Richard, P.1    Donahue, R.P.2    Stranges, S.3
  • 68
    • 0035985243 scopus 로고    scopus 로고
    • Prevention of diabetic nephropathy in mice by a diet low in glycoxidation products
    • Zheng F., He C., Cai W., et al. Prevention of diabetic nephropathy in mice by a diet low in glycoxidation products. Diabetes Metab Res Rev 2002, 18(3):224-237.
    • (2002) Diabetes Metab Res Rev , vol.18 , Issue.3 , pp. 224-237
    • Zheng, F.1    He, C.2    Cai, W.3
  • 69
    • 84888108332 scopus 로고    scopus 로고
    • Early progression of diabetic nephropathy correlates with methylglyoxal-derived advanced glycation end products
    • [Epub ahead of print]
    • Beisswenger P.J., Howell S.K., Russell G.B., et al. Early progression of diabetic nephropathy correlates with methylglyoxal-derived advanced glycation end products. Diabetes Care 2013, [Epub ahead of print].
    • (2013) Diabetes Care
    • Beisswenger, P.J.1    Howell, S.K.2    Russell, G.B.3
  • 70
    • 79956213781 scopus 로고    scopus 로고
    • Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the Joslin 50-Year Medalist Study
    • Sun J.K., Keenan H.A., Cavallerano J.D., et al. Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the Joslin 50-Year Medalist Study. Diabetes Care 2011, 34(4):968-974.
    • (2011) Diabetes Care , vol.34 , Issue.4 , pp. 968-974
    • Sun, J.K.1    Keenan, H.A.2    Cavallerano, J.D.3
  • 71
    • 84857942316 scopus 로고    scopus 로고
    • Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes
    • Gohda T., Niewczas M.A., Ficociello L.H., et al. Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes. JAm Soc Nephrol 2012, 23(3):516-524.
    • (2012) JAm Soc Nephrol , vol.23 , Issue.3 , pp. 516-524
    • Gohda, T.1    Niewczas, M.A.2    Ficociello, L.H.3
  • 72
    • 84857938428 scopus 로고    scopus 로고
    • Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes
    • Niewczas M.A., Gohda T., Skupien J., et al. Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes. JAm Soc Nephrol 2012, 23(3):507-515.
    • (2012) JAm Soc Nephrol , vol.23 , Issue.3 , pp. 507-515
    • Niewczas, M.A.1    Gohda, T.2    Skupien, J.3
  • 73
    • 77952049573 scopus 로고    scopus 로고
    • Induction of diabetes in aged C57B6 mice results in severe nephropathy: an association with oxidative stress, endoplasmic reticulum stress, and inflammation
    • Wu J., Zhang R., Torreggiani M., et al. Induction of diabetes in aged C57B6 mice results in severe nephropathy: an association with oxidative stress, endoplasmic reticulum stress, and inflammation. Am J Pathol 2010, 176(5):2163-2176.
    • (2010) Am J Pathol , vol.176 , Issue.5 , pp. 2163-2176
    • Wu, J.1    Zhang, R.2    Torreggiani, M.3
  • 74
    • 1642504872 scopus 로고    scopus 로고
    • Glycoxidation and inflammation in renal failure patients
    • Peppa M., Uribarri J., Cai W., et al. Glycoxidation and inflammation in renal failure patients. Am J Kidney Dis 2004, 43(4):690-695.
    • (2004) Am J Kidney Dis , vol.43 , Issue.4 , pp. 690-695
    • Peppa, M.1    Uribarri, J.2    Cai, W.3
  • 75
    • 84869426522 scopus 로고    scopus 로고
    • Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: a modern paradigm shift
    • Vlassara H., Cai W., Chen X., et al. Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: a modern paradigm shift. JGerontol A Biol Sci Med Sci 2012, 67(12):1410-1416.
    • (2012) JGerontol A Biol Sci Med Sci , vol.67 , Issue.12 , pp. 1410-1416
    • Vlassara, H.1    Cai, W.2    Chen, X.3
  • 76
    • 84873996013 scopus 로고    scopus 로고
    • Type 2 diabetes and 1-year mortality in intensive care unit patients
    • Christiansen C.F., Johansen M.B., Christensen S., et al. Type 2 diabetes and 1-year mortality in intensive care unit patients. Eur J Clin Invest 2013, 43(3):238-247.
    • (2013) Eur J Clin Invest , vol.43 , Issue.3 , pp. 238-247
    • Christiansen, C.F.1    Johansen, M.B.2    Christensen, S.3
  • 77
    • 84875787136 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with a Mediterranean diet
    • Estruch R., Ros E., Salas-Salvado J., et al. Primary prevention of cardiovascular disease with a Mediterranean diet. NEngl J Med 2013, 368(14):1279-1290.
    • (2013) NEngl J Med , vol.368 , Issue.14 , pp. 1279-1290
    • Estruch, R.1    Ros, E.2    Salas-Salvado, J.3
  • 78
    • 84888112697 scopus 로고    scopus 로고
    • Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study
    • Jasuja G.K., Travison T.G., Davda M., et al. Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study. Diabetes Care 2013, 36:2591-2596.
    • (2013) Diabetes Care , vol.36 , pp. 2591-2596
    • Jasuja, G.K.1    Travison, T.G.2    Davda, M.3
  • 79
    • 84859354773 scopus 로고    scopus 로고
    • Effect of dietary advanced glycation end products on mouse liver
    • Patel R., Baker S.S., Liu W., et al. Effect of dietary advanced glycation end products on mouse liver. PLoS One 2012, 7(4):e35143.
    • (2012) PLoS One , vol.7 , Issue.4
    • Patel, R.1    Baker, S.S.2    Liu, W.3
  • 80
    • 84867861053 scopus 로고    scopus 로고
    • Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models
    • Miyashita T., Toyoda Y., Tsuneyama K., et al. Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models. JToxicol Sci 2012, 37(5):931-942.
    • (2012) JToxicol Sci , vol.37 , Issue.5 , pp. 931-942
    • Miyashita, T.1    Toyoda, Y.2    Tsuneyama, K.3
  • 81
    • 84862829188 scopus 로고    scopus 로고
    • Oestradiol is a protective factor for non-alcoholic fatty liver disease in healthy men
    • Tian G.X., Sun Y., Pang C.J., et al. Oestradiol is a protective factor for non-alcoholic fatty liver disease in healthy men. Obes Rev 2012, 13(4):381-387.
    • (2012) Obes Rev , vol.13 , Issue.4 , pp. 381-387
    • Tian, G.X.1    Sun, Y.2    Pang, C.J.3
  • 82
    • 83055197017 scopus 로고    scopus 로고
    • Hormone replacement therapy in menopausal women: risk factor or protection to nonalcoholic fatty liver disease?
    • Florentino G., Cotrim H.P., Florentino A., et al. Hormone replacement therapy in menopausal women: risk factor or protection to nonalcoholic fatty liver disease?. Ann Hepatol 2012, 11(1):147-149.
    • (2012) Ann Hepatol , vol.11 , Issue.1 , pp. 147-149
    • Florentino, G.1    Cotrim, H.P.2    Florentino, A.3
  • 83
    • 79951703324 scopus 로고    scopus 로고
    • Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes?
    • Mericq V., Piccardo C., Cai W., et al. Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes?. Diabetes Care 2010, 33(10):2232-2237.
    • (2010) Diabetes Care , vol.33 , Issue.10 , pp. 2232-2237
    • Mericq, V.1    Piccardo, C.2    Cai, W.3
  • 84
    • 42549098465 scopus 로고    scopus 로고
    • Plasma concentration and urinary excretion of N epsilon-(carboxymethyl)lysine in breast milk- and formula-fed infants
    • Sebekova K., Saavedra G., Zumpe C., et al. Plasma concentration and urinary excretion of N epsilon-(carboxymethyl)lysine in breast milk- and formula-fed infants. Ann N Y Acad Sci 2008, 1126:177-180.
    • (2008) Ann N Y Acad Sci , vol.1126 , pp. 177-180
    • Sebekova, K.1    Saavedra, G.2    Zumpe, C.3
  • 85
    • 0142121508 scopus 로고    scopus 로고
    • Therapeutic potential of breakers of advanced glycation end product-protein crosslinks. Archives of biochemistry and biophysics
    • Vasan S., Foiles P., Founds H. Therapeutic potential of breakers of advanced glycation end product-protein crosslinks. Archives of biochemistry and biophysics. Arch Biochem Biophys 2003, 419(1):89-96.
    • (2003) Arch Biochem Biophys , vol.419 , Issue.1 , pp. 89-96
    • Vasan, S.1    Foiles, P.2    Founds, H.3
  • 86
    • 84878648578 scopus 로고    scopus 로고
    • Site-specific AGE modifications in the extracellular matrix: a role for glyoxal in protein damage in diabetes
    • Voziyan P., Brown K.L., Chetyrkin S., et al. Site-specific AGE modifications in the extracellular matrix: a role for glyoxal in protein damage in diabetes. Clin Chem Lab Med 2013, 13:1-7.
    • (2013) Clin Chem Lab Med , vol.13 , pp. 1-7
    • Voziyan, P.1    Brown, K.L.2    Chetyrkin, S.3
  • 87
    • 84863393388 scopus 로고    scopus 로고
    • For the Collaborative Study Group. Pyridorin in type 2 diabetic nephropathy
    • Lewis E.J., Greene T., Spitalewiz S., et al. For the Collaborative Study Group. Pyridorin in type 2 diabetic nephropathy. J Am Soc Nephrol 2012, 23:131-136.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 131-136
    • Lewis, E.J.1    Greene, T.2    Spitalewiz, S.3
  • 88
    • 34248374811 scopus 로고    scopus 로고
    • Effects of low- and high-advanced glycation endproduct meals on macro- and microvascular endothelial function and oxidative stress in patients with type 2 diabetes mellitus
    • Negrean M., Stirban A., Stratmann B., et al. Effects of low- and high-advanced glycation endproduct meals on macro- and microvascular endothelial function and oxidative stress in patients with type 2 diabetes mellitus. Am J Clin Nutr 2007, 85(5):1236-1243.
    • (2007) Am J Clin Nutr , vol.85 , Issue.5 , pp. 1236-1243
    • Negrean, M.1    Stirban, A.2    Stratmann, B.3
  • 89
    • 84884724567 scopus 로고    scopus 로고
    • A randomized, double-blind, crossover, placebo-controlled trial of 6 weeks benfotiamine treatment on postprandial vascular function and variables of autonomic nerve function in Type 2 diabetes
    • [Epub ahead of print]
    • Stirban A., Pop A., Tschoepe D. A randomized, double-blind, crossover, placebo-controlled trial of 6 weeks benfotiamine treatment on postprandial vascular function and variables of autonomic nerve function in Type 2 diabetes. Diabet Med 2013, [Epub ahead of print].
    • (2013) Diabet Med
    • Stirban, A.1    Pop, A.2    Tschoepe, D.3
  • 90
    • 0034646372 scopus 로고    scopus 로고
    • An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness
    • Asif M., Egan J., Vasan S., et al. An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness. Proc Natl Acad Sci USA 2000, 97(6):2809-2813.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.6 , pp. 2809-2813
    • Asif, M.1    Egan, J.2    Vasan, S.3


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