Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation

CNS and Neurological Disorders - Drug Targets

Volumn 12, Issue 6, 2013, Pages 849-860

  Grelli, Kimberly N ^a   Palubinsky, Amy M ^a,b,c   Cozette Kale, A ^b,c   Lizama Manibusan, Britney N ^a   Stankowski, Jeannette N ^a,c   Milne, Ginger L ^b   Singer, Robert ^a,b   McLaughlin, BethAnn ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Energetics; Galactose challenge; Glioblastoma; Ischemia; Isocitrate dehydrogenase; Mitochondria; Oxidative stress; Oxygen glucose deprivation (OGD); Preconditioning; Stroke

Indexed keywords

2 OXOGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; GALACTOSE; GLUTAMIC ACID; GLUTATHIONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; ISOCITRATE DEHYDROGENASE 3; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ADAPTATION; ANIMAL CELL; ARTICLE; BRAIN ISCHEMIA; CELL ENERGY; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LIPID PEROXIDATION; MUTATION; NEUROADAPTATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEOMICS; RAT; WESTERN BLOTTING;

ACUTE DISEASE; ADAPTATION, PHYSIOLOGICAL; ANIMALS; BRAIN ISCHEMIA; CELL LINE, TRANSFORMED; CELLS, CULTURED; CEREBRAL CORTEX; ENERGY METABOLISM; ISOCITRATE DEHYDROGENASE; MICE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84888042014     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/18715273113129990062     Document Type: Article

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