Inactivation of NADP+-dependent isocitrate dehydrogenase by nitric oxide

Free Radical Biology and Medicine

Volumn 33, Issue 7, 2002, Pages 927-937

  Yang, Eun Sun ^a   Richter, Christoph ^b   Chun, Jang Soo ^c   Huh, Tae Lin ^a   Kang, Shin Sung ^a   Park, Jeen Woo ^a  

^a Kyungpook National University   (South Korea)

^b ETH ZURICH   (Switzerland)

^c Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Antioxidant defense; Free radicals; Isocitrate dehydrogenase; S nitrosothiol; S nitrosylation

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); AMINO ACID; ANTIOXIDANT; CELL ENZYME; CYSTEINE; DIETHYLAMINE; ENDOGENOUS COMPOUND; FLUORESCENT DYE; ISOCITRATE DEHYDROGENASE; LINSIDOMINE; LIPOPOLYSACCHARIDE; N ETHYLCARBAMIDE; N(G) METHYLARGININE; N,N' DIMETHYL N IODOACETYL N'(7 NITROBENZ 2 OXA 1,3 DIAZOL 4 YL)ETHYLENEAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; PROTEINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; S NITROSOTHIOL; SPERMINE; SPERMINE NONOATE; SUPEROXIDE DISMUTASE; THIOL GROUP; TRYPTOPHAN; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL DAMAGE; CELL PROTECTION; CELL STRAIN; CONTROLLED STUDY; CYTOSOL; DEFENSE MECHANISM; DIGESTION; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MITOCHONDRION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; TIME;

ANIMALS; CELL LINE; CIRCULAR DICHROISM; ENDOPEPTIDASES; GLUTATHIONE; HUMANS; ISOCITRATE DEHYDROGENASE; KINETICS; MACROPHAGES; MICE; NADP; NITRIC OXIDE; NITRIC OXIDE DONORS; U937 CELLS;

EID: 0036803015     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00981-4     Document Type: Article

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