Methylmalonate toxicity in primary neuronal cultures

Neuroscience

Volumn 86, Issue 1, 1998, Pages 279-290

  McLaughlin, B A ^a   Nelson, D ^a   Silver, I A ^b   Erecinska, M ^a   Chesselet, M F ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Calcium; Free radicals; Huntington's disease; Inhibition of ATP production; Malonate; Striatum

Indexed keywords

METHYLMALONIC ACID;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; CELL MATURATION; CORPUS STRIATUM; DNA STRAND BREAKAGE; HUNTINGTON CHOREA; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PHOSPHATE METABOLISM; PRIORITY JOURNAL; RAT;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; ASPARTIC ACID; BRAIN; CALCIUM; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CORPUS STRIATUM; ELECTRON TRANSPORT COMPLEX II; FETUS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; KINETICS; METHYLMALONIC ACID; MICE; MICROSCOPY, VIDEO; MULTIENZYME COMPLEXES; NEURONS; OXIDOREDUCTASES; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SUCCINATE DEHYDROGENASE; TIME FACTORS;

EID: 0031841091     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00594-0     Document Type: Article

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