Metabolism unhinged: IDH mutations in cancer

Nature Medicine

Volumn 17, Issue 3, 2011, Pages 291-293

  Prensner, John R ^a,b   Chinnaiyan, Arul M ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYGLUTARIC ACID; 2 OXOGLUTARIC ACID; ARGININE; DIOXYGENASE; DNA; HISTONE DEMETHYLASE; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE ISOENZYME; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BREAST CANCER; CANCER GRADING; CARCINOGENESIS; CELL METABOLISM; CELL RESPIRATION; CHEMOSENSITIVITY; COLON CANCER; COMPETITIVE INHIBITION; CYTOPLASM; DNA METHYLATION; DRUG TARGETING; EPIGENETICS; GENE MUTATION; GLIOBLASTOMA; HIGH THROUGHPUT SCREENING; HUMAN; IDH1 GENE; IDH2 GENE; LIQUID CHROMATOGRAPHY; MALIGNANT NEOPLASTIC DISEASE; MASS SPECTROMETRY; MITOCHONDRION; NONHUMAN; ONCOGENE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROGRESSION FREE SURVIVAL; PROTEIN STRUCTURE; TET2 GENE;

GLIOBLASTOMA; HUMANS; ISOCITRATE DEHYDROGENASE; LEUKEMIA; MUTATION;

EID: 79952366279     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm0311-291     Document Type: Article

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