IDH1 Mutations in Gliomas: When an Enzyme Loses Its Grip

Cancer Cell

Volumn 17, Issue 1, 2010, Pages 7-9

  Frezza, Christian ^a   Tennant, Daniel A ^a   Gottlieb, Eyal ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYGLUTARIC ACID; ISOCITRATE DEHYDROGENASE 1; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG;

CARCINOGENESIS; CELL METABOLISM; CITRIC ACID CYCLE; CLINICAL FEATURE; CYTOSOL; ENZYME ACTIVITY; ENZYME ANALYSIS; GLIOMA; HUMAN; MITOCHONDRIAL MEMBRANE; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SHORT SURVEY; TUMOR SUPPRESSOR GENE;

EID: 73649145880     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2009.12.031     Document Type: Short Survey

References (10)

1. Aghili M., Zahedi F., and Rafiee E. J. Neurooncol. 91 (2009) 233-236
2. Dang L., White D.W., Gross S., Bennett B.D., Bittinger M.A., Driggers E.M., Fantin V.R., Jang H.G., Jin S., Keenan M.C., et al. Nature 462 (2009) 739-744
3. King A., Selak M.A., and Gottlieb E. Oncogene 25 (2006) 4675-4682
4. MacKenzie E.D., Selak M.A., Tennant D.A., Payne L.J., Crosby S., Frederiksen C.M., Watson D.G., and Gottlieb E. Mol. Cell. Biol. 27 (2007) 3282-3289
5. Parsons D.W., Jones S., Zhang X., Lin J.C., Leary R.J., Angenendt P., Mankoo P., Carter H., Siu I.M., Gallia G.L., et al. Science 321 (2008) 1807-1812
6. Struys E.A. J. Inherit. Metab. Dis. 29 (2006) 21-29
7. Xu X., Zhao J., Xu Z., Peng B., Huang Q., Arnold E., and Ding J. J. Biol. Chem. 279 (2004) 33946-33957
8. Yan H., Bigner D.D., Velculescu V., and Parsons D.W. Cancer Res. 69 (2009) 9157-9159
9. Yan H., Parsons D.W., Jin G., McLendon R., Rasheed B.A., Yuan W., Kos I., Batinic-Haberle I., Jones S., Riggins G.J., et al. N. Engl. J. Med. 360 (2009) 765-773
10. Zhao S., Lin Y., Xu W., Jiang W., Zha Z., Wang P., Yu W., Li Z., Gong L., Peng Y., et al. Science 324 (2009) 261-265