Rutin activates the MAPK pathway and BDNF gene expression on beta-amyloid induced neurotoxicity in rats

Toxicology Letters

Volumn 224, Issue 1, 2014, Pages 108-113

  Moghbelinejad, Sahar ^a   Nassiri Asl, Marjan ^a   Naserpour Farivar, Taghi ^a   Abbasi, Esmail ^a   Sheikhi, Mehdi ^b   Taghiloo, Mina ^a   Farsad, Farzaneh ^a   Samimi, Amir ^a   Hajiali, Farid ^a  

^a QAZVIN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

BDNF; MAP kinase; Memory; Neurotoxicity; Rutin

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BETA ACTIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RUTOSIDE; SODIUM CHLORIDE; THIOL GROUP;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; MEMORY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RAT; TREATMENT DURATION;

Β-AMYLOID; AΒ; ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN; AD; AKT/PKB; ALZHEIMER'S DISEASE; ARC; BDNF; BRAIN-DERIVED NEUROTROPHIC FACTOR; C-JUN N-TERMINAL KINASE; CAMP RESPONSE ELEMENT-BINDING PROTEIN; CAT; CATALASE; CREB; ERK1/2; EXTRACELLULAR SIGNAL-REGULATED PROTEIN KINASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GPX; GSH; I.P.; INTERAPERITONEALLY; JNK; MALONDIALDEHYDE; MAMMALIAN TARGET OF RAPAMYCIN; MAP KINASE; MCAO; MDA; MEK1/2; MEMORY; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOGEN ACTIVATED KINASE KINASE; MITOGEN-ACTIVATED PROTEIN KINASE; MTOR; NEUROTOXICITY; PBS; PENTYLENETETRAZOLE; PHOSPHATE BUFFERED SALINE; PHOSPHATIDYL INOSITIOL 3-KINASE; PI3K; PROTEIN KINASE B; PTZ; REACTIVE OXYGEN SPECIES; ROS; RUTIN; SH; SOD; SULFHYDRYL; SUPEROXIDE DISMUTASE; TRKB; TROPOMYOSIN RECEPTOR KINASE B;

AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; MALE; MAP KINASE SIGNALING SYSTEM; NEUROTOXICITY SYNDROMES; RATS; RATS, WISTAR; RUTIN;

EID: 84887534623     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.10.010     Document Type: Article

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