Cyclic AMP response element-binding protein (CREB) phosphorylation: A mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics

Biochemical Pharmacology

Volumn 83, Issue 6, 2012, Pages 705-714

  Bitner, R Scott ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Alzheimer's disease; CREB phosphorylation; H3 antagonist; HSD1 inhibitor; 7 nAChR agonist

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; 5 (4 CYANOPHENYL) 2 [2 (2 METHYL 1 IMIDAZOLIDINYL)ETHYL]BENZOFURAN; A 918446; BRAIN DERIVED NEUROTROPHIC FACTOR; BUNGAROTOXIN RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HISTAMINE H3 RECEPTOR ANTAGONIST; LIGAND GATED ION CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINIC AGENT; OXIDOREDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CINGULATE GYRUS; COGNITION; CONTROLLED STUDY; GENE EXPRESSION; HIPPOCAMPUS; HUMAN; IMMUNOHISTOCHEMISTRY; LEARNING; MAZE TEST; MEMORY; NERVE CELL PLASTICITY; NERVE CONDUCTION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVIEW; SYNAPTIC TRANSMISSION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 84857063922     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.11.009     Document Type: Note

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