Metastasis awakening: The challenges of targeting minimal residual cancer

Nature Medicine

Volumn 19, Issue 3, 2013, Pages 274-275

  Polzer, Bernhard ^a   Klein, Christoph A ^a,b  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEFITINIB; TRASTUZUMAB;

ARTICLE; BREAST CANCER; CELL PROLIFERATION; COLORECTAL CANCER; DISEASE FREE SURVIVAL; DRUG EFFICACY; GENE AMPLIFICATION; HEAD AND NECK CANCER; HUMAN; LUNG CANCER; LUNG NON SMALL CELL CANCER; MELANOMA; METASTASIS; MOLECULARLY TARGETED THERAPY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RISK BENEFIT ANALYSIS;

ANTINEOPLASTIC AGENTS; CHEMOTHERAPY, ADJUVANT; DRUG RESISTANCE, NEOPLASM; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASM METASTASIS; NEOPLASM, RESIDUAL; NEOPLASMS; NEOPLASTIC CELLS, CIRCULATING; TREATMENT OUTCOME;

EID: 84875183611     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3121     Document Type: Article

References (17)

1. Douillard, J.Y. et al. J. Clin. Oncol. 28, 4697-4705 (2010).
2. Slamon, D.J. et al. N. Engl. J. Med. 344, 783-792 (2001).
3. Sosman, J.A. et al. N. Engl. J. Med. 366, 707-714 (2012).
4. Mok, T.S. et al. N. Engl. J. Med. 361, 947-957 (2009).
5. Gianni, L. et al. Lancet Oncol. 12, 236-244 (2011).
6. Alberts, S.R. et al. J. Am. Med. Assoc. 307, 1383-1393 (2012).
7. Goss, G.D. et al. J. Clin. Oncol. 28, Suppl 18s, LBA7005 (2010).
8. Sullivan, R.J. & Flaherty, K.T. Eur. J. Cancer published online, doi:10.1016/j.ejca.2012.11.019 (2 January 2013).
9. Liu, D., Aguirre Ghiso, J., Estrada, Y. & Ossowski, L. Cancer Cell 1, 445-457 (2002).
10. Adam, A.P. et al. Cancer Res. 69, 5664-5672 (2009).
11. Stoecklein, N.H. & Klein, C.A. Int. J. Cancer 126, 589-598 (2010).
12. Gow, C.H. et al. Ann. Oncol. 20, 696-702 (2009).
13. Schardt, J.A. et al. Cancer Cell 8, 227-239 (2005).
14. Dent, R. et al. Clin. Cancer Res. 13, 4429-4434 (2007).
15. Bouwman, P. et al. Nat. Struct. Mol. Biol. 17, 688-695 (2010).
16. Gerlinger, M. et al. N. Engl. J. Med. 366, 883-892 (2012).
17. Nik-Zainal, S. et al. Cell 149, 994-1007 (2012).