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Volumn 15, Issue 7, 2013, Pages 807-817

The perivascular niche regulates breast tumour dormancy

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOSPONDIN 1; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84880332704     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2767     Document Type: Article
Times cited : (869)

References (64)
  • 1
    • 35548936833 scopus 로고    scopus 로고
    • Mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso, J. A. Models, mechanisms and clinical evidence for cancer dormancy. Nat. Rev. Cancer 7, 834-846 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 834-846
    • Aguirre-Ghiso, J.A.1    Models, J.2
  • 2
    • 78649467513 scopus 로고    scopus 로고
    • Does tumour dormancy offer a therapeutic target
    • Goss, P. E. & Chambers, A. F. Does tumour dormancy offer a therapeutic target? Nat. Rev. Cancer 10, 871-877 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 871-877
    • Goss, P.E.1    Chambers, A.F.2
  • 3
    • 63049102497 scopus 로고    scopus 로고
    • Parallel progression of primary tumours and metastases
    • Klein, C. A. Parallel progression of primary tumours and metastases. Nat. Rev. Cancer 9, 302-312 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 302-312
    • Klein, C.A.1
  • 4
    • 79961087495 scopus 로고    scopus 로고
    • Controversies in clinical cancer dormancy
    • Uhr, J. W. & Pantel, K. Controversies in clinical cancer dormancy. Proc. Natl Acad. Sci. USA 108, 12396-12400 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 12396-12400
    • Uhr, J.W.1    Pantel, K.2
  • 5
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
    • Kaplan, R. N. et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438, 820-827 (2005).
    • (2005) Nature , vol.438 , pp. 820-827
    • Kaplan, R.N.1
  • 6
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • Peinado, H. et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. Med. 18, 883-891 (2012).
    • (2012) Nat. Med , vol.18 , pp. 883-891
    • Peinado, H.1
  • 7
    • 63049121364 scopus 로고    scopus 로고
    • The metastatic niche:adapting the foreign soil
    • Psaila, B. & Lyden, D. The metastatic niche:adapting the foreign soil. Nat. Rev. Cancer 9, 285-293 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 285-293
    • Psaila, B.1    Lyden, D.2
  • 8
    • 33746620430 scopus 로고    scopus 로고
    • Dormant cancer cells retrieved from metastasis-free organs regain tumorigenic and metastatic potency
    • Suzuki, M., Mose, E. S., Montel, V. & Tarin, D. Dormant cancer cells retrieved from metastasis-free organs regain tumorigenic and metastatic potency. Am. J. Pathol. 169, 673-681 (2006).
    • (2006) Am. J. Pathol , vol.169 , pp. 673-681
    • Suzuki, M.1    Mose, E.S.2    Montel, V.3    Tarin, D.4
  • 9
    • 0036532065 scopus 로고    scopus 로고
    • Persistence of solitary mammary carcinoma cells in a secondary site:A possible contributor to dormancy
    • Naumov, G. N. et al. Persistence of solitary mammary carcinoma cells in a secondary site:A possible contributor to dormancy. Cancer Res. 62, 2162-2168 (2002).
    • (2002) Cancer Res , vol.62 , pp. 2162-2168
    • Naumov, G.N.1
  • 10
    • 0027235985 scopus 로고
    • Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells
    • Pantel, K. et al. Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells. J. Natl. Cancer Inst. 85, 1419-1424 (1993).
    • (1993) J. Natl. Cancer Inst , vol.85 , pp. 1419-1424
    • Pantel, K.1
  • 11
    • 79952392467 scopus 로고    scopus 로고
    • Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
    • Bissell, M. J. & Hines, W. C. Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat. Med. 17, 320-329 (2011).
    • (2011) Nat. Med , vol.17 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 12
    • 0028927484 scopus 로고
    • Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
    • Boudreau, N., Sympson, C. J., Werb, Z. & Bissell, M. J. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267, 891-893 (1995).
    • (1995) Science , vol.267 , pp. 891-893
    • Boudreau, N.1    Sympson, C.J.2    Werb, Z.3    Bissell, M.J.4
  • 13
    • 78751633931 scopus 로고    scopus 로고
    • Depletion of nuclear actin is a key mediator of quiescence in epithelial cells
    • Spencer, V. A. et al. Depletion of nuclear actin is a key mediator of quiescence in epithelial cells. J. Cell Sci. 124, 123-132 (2011).
    • (2011) J. Cell Sci , vol.124 , pp. 123-132
    • Spencer, V.A.1
  • 14
    • 0036726312 scopus 로고    scopus 로고
    • -4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
    • Weaver, V. M. et al. -4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2, 205-216 (2002).
    • (2002) Cancer Cell , vol.2 , pp. 205-216
    • Weaver, V.M.1
  • 15
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver, V. M. et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J. Cell Biol. 137, 231-245 (1997).
    • (1997) J. Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1
  • 16
    • 0020456385 scopus 로고
    • How does the extracellular matrix direct gene expression
    • Bissell, M. J., Hall, H. G. & Parry, G. How does the extracellular matrix direct gene expression? J. Theor. Biol. 99, 31-68 (1982).
    • (1982) J. Theor. Biol , vol.99 , pp. 31-68
    • Bissell, M.J.1    Hall, H.G.2    Parry, G.3
  • 17
    • 0026738947 scopus 로고
    • Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells
    • Petersen, O. W., Ronnov-Jessen, L., Howlett, A. R. & Bissell, M. J. Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc. Natl Acad. Sci. USA 89, 9064-9068 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 9064-9068
    • Petersen, O.W.1    Ronnov-Jessen, L.2    Howlett, A.R.3    Bissell, M.J.4
  • 18
    • 23944466427 scopus 로고    scopus 로고
    • A pooled analysis of bone marrow micrometastasis in breast cancer
    • Braun, S. et al. A pooled analysis of bone marrow micrometastasis in breast cancer. New Engl. J. Med. 353, 793-802 (2005).
    • (2005) New Engl. J. Med , vol.353 , pp. 793-802
    • Braun, S.1
  • 19
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • Chambers, A. F., Groom, A. C. & MacDonald, I. C. Dissemination and growth of cancer cells in metastatic sites. Nat. Rev. Cancer 2, 563-572 (2002).
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    MacDonald, I.C.3
  • 20
    • 79251468712 scopus 로고    scopus 로고
    • Mouse models of advanced spontaneous metastasis for experimental therapeutics
    • Francia, G., Cruz-Munoz, W., Man, S., Xu, P. & Kerbel, R. S. Mouse models of advanced spontaneous metastasis for experimental therapeutics. Nat. Rev. Cancer 11, 135-141 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 135-141
    • Francia, G.1    Cruz-Munoz, W.2    Man, S.3    Xu, P.4    Kerbel, R.S.5
  • 21
    • 0024708518 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • Paget, S. The distribution of secondary growths in cancer of the breast. Cancer Metast. Rev. 8, 98-101 (1989).
    • (1989) Cancer Metast. Rev , vol.8 , pp. 98-101
    • Paget, S.1
  • 22
    • 0029872839 scopus 로고    scopus 로고
    • Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal
    • Briand, P., Nielsen, K. V., Madsen, M. W. & Petersen, O. W. Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal. Cancer Res. 56, 2039-2044 (1996).
    • (1996) Cancer Res , vol.56 , pp. 2039-2044
    • Briand, P.1    Nielsen, K.V.2    Madsen, M.W.3    Petersen, O.W.4
  • 23
    • 77449121923 scopus 로고    scopus 로고
    • Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells
    • Butler, J. M. et al. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell 6, 251-264 (2010).
    • (2010) Cell Stem Cell , vol.6 , pp. 251-264
    • Butler, J.M.1
  • 24
    • 58049221111 scopus 로고    scopus 로고
    • Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene
    • Seandel, M. et al. Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proc. Natl Acad. Sci. USA 105, 19288-19293 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 19288-19293
    • Seandel, M.1
  • 25
    • 75149149879 scopus 로고    scopus 로고
    • Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors
    • Butler, J. M., Kobayashi, H. & Ra-i, S. Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nat. Rev. Cancer 10, 138-146 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 138-146
    • Butler, J.M.1    Kobayashi, H.2    Ra-I, S.3
  • 26
    • 67249129599 scopus 로고    scopus 로고
    • Mural cell associated VEGF is required for organotypic vessel formation
    • Evensen, L. et al. Mural cell associated VEGF is required for organotypic vessel formation. PLoS ONE 4, e5798 (2009).
    • (2009) PLos ONE , vol.4 , pp. 5798
    • Evensen, L.1
  • 27
    • 0028609624 scopus 로고
    • Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis
    • Weinstat-Saslow, D. L. et al. Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res. 54, 6504-6511 (1994).
    • (1994) Cancer Res , vol.54 , pp. 6504-6511
    • Weinstat-Saslow, D.L.1
  • 28
    • 0029797025 scopus 로고    scopus 로고
    • Regulation of tumor growth and metastasis by thrombospondin-1
    • Roberts, D. D. Regulation of tumor growth and metastasis by thrombospondin-1. FASEB J. 10, 1183-1191 (1996).
    • (1996) FASEB J , vol.10 , pp. 1183-1191
    • Roberts, D.D.1
  • 29
    • 41449114479 scopus 로고    scopus 로고
    • The effect of matrix density on the regulation of 3-D capillary morphogenesis
    • Ghajar, C. M. et al. The effect of matrix density on the regulation of 3-D capillary morphogenesis. Biophys. J. 94, 1930-1941 (2008).
    • (2008) Biophys. J , vol.94 , pp. 1930-1941
    • Ghajar, C.M.1
  • 30
    • 33847046849 scopus 로고    scopus 로고
    • Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
    • Hellstrom, M. et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445, 776-780 (2007).
    • (2007) Nature , vol.445 , pp. 776-780
    • Hellstrom, M.1
  • 31
    • 84862005373 scopus 로고    scopus 로고
    • ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1
    • Avraham-Davidi, I. et al. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nat. Med. 18, 967-973 (2012).
    • (2012) Nat. Med , vol.18 , pp. 967-973
    • Avraham-Davidi, I.1
  • 32
    • 58149269348 scopus 로고    scopus 로고
    • Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
    • Kim, S. et al. Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. Nature 457, 102-106 (2009).
    • (2009) Nature , vol.457 , pp. 102-106
    • Kim, S.1
  • 33
    • 84855425160 scopus 로고    scopus 로고
    • Interactions between cancer stem cells and their niche govern metastatic colonization
    • Malanchi, I. et al. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 481, 85-89 (2012).
    • (2012) Nature , vol.481 , pp. 85-89
    • Malanchi, I.1
  • 34
    • 79960117895 scopus 로고    scopus 로고
    • Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
    • Oskarsson, T. et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat. Med. 17, 867-874 (2011).
    • (2011) Nat. Med , vol.17 , pp. 867-874
    • Oskarsson, T.1
  • 35
    • 77954565543 scopus 로고    scopus 로고
    • Metastatic outgrowth encompasses COL-I, FN1, and POSTN up-regulation and assembly to -brillar networks regulating cell adhesion, migration, and growth
    • Soikkeli, J. et al. Metastatic outgrowth encompasses COL-I, FN1, and POSTN up-regulation and assembly to -brillar networks regulating cell adhesion, migration, and growth. Am. J. Pathol. 177, 387-403 (2010).
    • (2010) Am. J. Pathol , vol.177 , pp. 387-403
    • Soikkeli, J.1
  • 36
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment:TGF-: The molecular Jekyll and Hyde of cancer
    • Bierie, B. & Moses, H. L. Tumour microenvironment:TGF-:the molecular Jekyll and Hyde of cancer. Nat. Rev. Cancer 6, 506-520 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 37
    • 0035914069 scopus 로고    scopus 로고
    • Liver organogenesis promoted by endothelial cells prior to vascular function
    • Matsumoto, K., Yoshitomi, H., Rossant, J. & Zaret, K. S. Liver organogenesis promoted by endothelial cells prior to vascular function. Science 294, 559-563 (2001).
    • (2001) Science , vol.294 , pp. 559-563
    • Matsumoto, K.1    Yoshitomi, H.2    Rossant, J.3    Zaret, K.S.4
  • 38
    • 80155137529 scopus 로고    scopus 로고
    • Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization
    • Ding, B. S. et al. Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 147, 539-553 (2011).
    • (2011) Cell , vol.147 , pp. 539-553
    • Ding, B.S.1
  • 39
    • 0035913986 scopus 로고    scopus 로고
    • Induction of pancreatic differentiation by signals from blood vessels
    • Lammert, E., Cleaver, O. & Melton, D. Induction of pancreatic differentiation by signals from blood vessels. Science 294, 564-567 (2001).
    • (2001) Scienc , vol.294 , pp. 564-567
    • Lammert, E.1    Cleaver, O.2    Melton, D.3
  • 40
    • 0027375595 scopus 로고
    • Density-dependent endothelial cell production of an inhibitor of smooth muscle cell growth
    • Dodge, A. B., Lu, X. & D'Amore, P. A. Density-dependent endothelial cell production of an inhibitor of smooth muscle cell growth. J. Cell Biochem. 53, 21-31 (1993).
    • (1993) J. Cell Biochem , vol.53 , pp. 21-31
    • Dodge, A.B.1    Lu, X.2    D'Amore, P.A.3
  • 41
    • 50849139576 scopus 로고    scopus 로고
    • A perivascular origin for mesenchymal stem cells in multiple human organs
    • Crisan, M. et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 3, 301-313 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 301-313
    • Crisan, M.1
  • 42
    • 78149280740 scopus 로고    scopus 로고
    • Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells
    • Kobayashi, H. et al. Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nat. Cell Biol. 12, 1046-1056 (2010).
    • (2010) Nat. Cell Biol , vol.12 , pp. 1046-1056
    • Kobayashi, H.1
  • 43
    • 2542626091 scopus 로고    scopus 로고
    • Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells
    • Shen, Q. et al. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 304, 1338-1340 (2004).
    • (2004) Scince , vol.304 , pp. 1338-1340
    • Shen, Q.1
  • 44
    • 84856147560 scopus 로고    scopus 로고
    • Endothelial and perivascular cells maintain haematopoietic stem cells
    • Ding, L., Saunders, T. L., Enikolopov, G. & Morrison, S. J. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 481, 457-462 (2012).
    • (2012) Nature , vol.481 , pp. 457-462
    • Ding, L.1    Saunders, T.L.2    Enikolopov, G.3    Morrison, S.J.4
  • 45
    • 33746791465 scopus 로고    scopus 로고
    • Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression
    • Bandyopadhyay, S. et al. Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression. Nat. Med. 12, 933-938 (2006).
    • (2006) Nat. Med , vol.12 , pp. 933-938
    • Bandyopadhyay, S.1
  • 46
    • 33846029123 scopus 로고    scopus 로고
    • A perivascular niche for brain tumor stem cells
    • Calabrese, C. et al. A perivascular niche for brain tumor stem cells. Cancer Cell 11, 69-82 (2007).
    • (2007) Cancer Cell , vol.11 , pp. 69-82
    • Calabrese, C.1
  • 47
    • 78751656154 scopus 로고    scopus 로고
    • Stromal endothelial cells directly in-uence cancer progression
    • Franses, J. W., Baker, A. B., Chitalia, V. C. & Edelman, E. R. Stromal endothelial cells directly in-uence cancer progression. Sci. Trans. Med. 3, 66ra65 (2011).
    • (2011) Sci. Trans. Med , vol.3 , pp. 66-65
    • Franses, J.W.1    Baker, A.B.2    Chitalia, V.C.3    Edelman, E.R.4
  • 48
    • 60549117358 scopus 로고    scopus 로고
    • Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy
    • Indraccolo, S. et al. Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy. Cancer Res. 69, 1314-1323 (2009).
    • (2009) Cancer Res , vol.69 , pp. 1314-1323
    • Indraccolo, S.1
  • 49
    • 84855453198 scopus 로고    scopus 로고
    • Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice
    • Panigrahy, D. et al. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J. Clin. Invest. 122, 178-191 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 178-191
    • Panigrahy, D.1
  • 50
    • 84875476748 scopus 로고    scopus 로고
    • Nascent endothelium initiates th2 polarization of asthma
    • Asosingh, K. et al. Nascent endothelium initiates th2 polarization of asthma. J. Immunol. 190, 3458-3465 (2013).
    • (2013) J. Immunol , vol.190 , pp. 3458-3465
    • Asosingh, K.1
  • 51
    • 0035911221 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin, E. Y., Nguyen, A. V., Russell, R. G. & Pollard, J. W. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J. Exp. Med. 193, 727-740 (2001).
    • (2001) J. Exp. Med , vol.193 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 52
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • Qian, B. Z. & Pollard, J. W. Macrophage diversity enhances tumor progression and metastasis. Cell 141, 39-51 (2010).
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 53
    • 67651160649 scopus 로고    scopus 로고
    • CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • DeNardo, D. G. et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16, 91-102 (2009).
    • (2009) Cancer Cell , vol.16 , pp. 91-102
    • Denardo, D.G.1
  • 54
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis:An organizing principle for drug discovery
    • Folkman, J. Angiogenesis:an organizing principle for drug discovery? Nat. Rev. Drug Discov. 6, 273-286 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 273-286
    • Folkman, J.1
  • 55
    • 77957607057 scopus 로고    scopus 로고
    • Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
    • Jakobsson, L. et al. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat. Cell Biol. 12, 943-953 (2010).
    • (2010) Nat. Cell Biol , vol.12 , pp. 943-953
    • Jakobsson, L.1
  • 56
    • 0028362876 scopus 로고
    • Requirement of vascular integrin -v-3 for angiogenesis
    • Brooks, P. C., Clark, R. A. & Cheresh, D. A. Requirement of vascular integrin -v-3 for angiogenesis. Science 264, 569-571 (1994).
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 57
    • 79953828409 scopus 로고    scopus 로고
    • VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines
    • Stratman, A. N., Davis, M. J. & Davis, G. E. VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood 117, 3709-3719 (2011).
    • (2011) Blood , vol.117 , pp. 3709-3719
    • Stratman, A.N.1    Davis, M.J.2    Davis, G.E.3
  • 58
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • Lee, G. Y., Kenny, P. A., Lee, E. H. & Bissell, M. J. Three-dimensional culture models of normal and malignant breast epithelial cells. Nat. Meth. 4, 359-365 (2007).
    • (2007) Nat. Meth , vol.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4
  • 59
    • 77955860340 scopus 로고    scopus 로고
    • Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice
    • Pitulescu, M. E., Schmidt, I., Benedito, R. & Adams, R. H. Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice. Nat. Protoc. 5, 1518-1534 (2010).
    • (2010) Nat. Protoc , vol.5 , pp. 1518-1534
    • Pitulescu, M.E.1    Schmidt, I.2    Benedito, R.3    Adams, R.H.4
  • 60
    • 70349856167 scopus 로고    scopus 로고
    • Arterial-venous segregation by selective cell sprouting:an alternative mode of blood vessel formation
    • Herbert, S. P. et al. Arterial-venous segregation by selective cell sprouting:an alternative mode of blood vessel formation. Science 326, 294-298 (2009).
    • (2009) Scince , vol.326 , pp. 294-298
    • Herbert, S.P.1
  • 61
    • 39149110311 scopus 로고    scopus 로고
    • The zebra-sh/tumor xenograft angiogenesis assay
    • Nicoli, S. & Presta, M. The zebra-sh/tumor xenograft angiogenesis assay. Nat. Protoc. 2, 2918-2923 (2007).
    • (2007) Nat. Protoc , vol.2 , pp. 2918-2923
    • Nicoli, S.1    Presta, M.2
  • 62
    • 0142151097 scopus 로고    scopus 로고
    • Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors
    • Baluk, P., Morikawa, S., Haskell, A., Mancuso, M. & McDonald, D. M. Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 163, 1801-1815 (2003).
    • (2003) Am. J. Pathol , vol.163 , pp. 1801-1815
    • Baluk, P.1    Morikawa, S.2    Haskell, A.3    Mancuso, M.4    McDonald, D.M.5
  • 63
    • 84857135531 scopus 로고    scopus 로고
    • Coherent angular motion in the establishment of multicellular architecture of glandular tissues
    • Tanner, K., Mori, H., Mroue, R., Bruni-Cardoso, A. & Bissell, M. J. Coherent angular motion in the establishment of multicellular architecture of glandular tissues. Proc. Natl Acad. Sci. USA 109, 1973-1978 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 1973-1978
    • Tanner, K.1    Mori, H.2    Mroue, R.3    Bruni-Cardoso, A.4    Bissell, M.J.5
  • 64
    • 78650220991 scopus 로고    scopus 로고
    • Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo
    • Beliveau, A. et al. Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo. Genes Dev. 24, 2800-2811 (2010).
    • (2010) Genes Dev , vol.24 , pp. 2800-2811
    • Beliveau, A.1


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