Acute peripheral GLP-1 receptor agonism or antagonism does not alter energy expenditure in rats after Roux-en-Y gastric bypass

Physiology and Behavior

Volumn 121, Issue , 2013, Pages 70-78

  Abegg, Kathrin ^a   Schiesser, Marc ^b   Lutz, Thomas A ^a   Bueter, Marco ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Energy expenditure; Glucagon like peptide 1; Indirect calorimetry; Roux en Y gastric bypass

Indexed keywords

EXENDIN 4; EXENDIN 9; GASTROINTESTINAL HORMONE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENDOCRINE SYSTEM; ENERGY EXPENDITURE; FOOD INTAKE; MALE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RAT; RESPIRATORY QUOTIENT; ROUX Y ANASTOMOSIS; STOMACH BYPASS; WEIGHT REDUCTION;

ENERGY EXPENDITURE; GLUCAGON-LIKE PEPTIDE-1; INDIRECT CALORIMETRY; ROUX-EN-Y GASTRIC BYPASS;

ACTIVITY CYCLES; ANIMALS; BODY WEIGHT; CALORIMETRY; EATING; ENERGY METABOLISM; FOOD DEPRIVATION; GASTRIC BYPASS; MALE; MOTOR ACTIVITY; PEPTIDE FRAGMENTS; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, GLUCAGON; RESPIRATION; TIME FACTORS; VENOMS;

EID: 84887157522     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2013.03.027     Document Type: Article

References (53)

1. Obesity: preventing and managing the global epidemic World Health Organ Tech. Rep. Ser 2000, 894:i-xii. 1-253.
2. Adams T.D., Davidson L.E., Litwin S.E., Kolotkin R.L., Lamonte M.J., Pendleton R.C., et al. Health benefits of gastric bypass surgery after 6years. JAMA 2012, 308:1122-1131.
3. Carlsson L.M., Peltonen M., Ahlin S., Anveden A., Bouchard C., Carlsson B., et al. Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects. N Engl J Med 2012, 367:695-704.
4. Mingrone G., Panunzi S., De G.A., Guidone C., Iaconelli A., Leccesi L., et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med 2012, 366:1577-1585.
5. Schauer P.R., Kashyap S.R., Wolski K., Brethauer S.A., Kirwan J.P., Pothier C.E., et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med 2012, 366:1567-1576.
6. Buchwald H., Oien D.M. Metabolic/bariatric surgery Worldwide 2008. Obes Surg 2009, 19:1605-1611.
7. Korner J., Bessler M., Cirilo L.J., Conwell I.M., Daud A., Restuccia N.L., et al. Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulin. J Clin Endocrinol Metab 2005, 90:359-365.
8. le Roux C.W., Aylwin S.J., Batterham R.L., Borg C.M., Coyle F., Prasad V., et al. Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters. Ann Surg 2006, 243:108-114.
9. le Roux C.W., Welbourn R., Werling M., Osborne A., Kokkinos A., Laurenius A., et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg 2007, 246:780-785.
10. Laurenius A., Larsson I., Bueter M., Melanson K.J., Bosaeus I., Forslund H.B., et al. Changes in eating behaviour and meal pattern following Roux-en-Y gastric bypass. Int J Obes (Lond) 2012, 36:348-355.
11. le Roux C.W., Bueter M., Theis N., Werling M., Ashrafian H., Lowenstein C., et al. Gastric bypass reduces fat intake and preference. Am J Physiol Regul Integr Comp Physiol 2011, 301:R1057-R1066.
12. Shin A.C., Zheng H., Pistell P.J., Berthoud H.R. Roux-en-Y gastric bypass surgery changes food reward in rats. Int J Obes (Lond) 2011, 35:642-651.
13. Zheng H., Shin A.C., Lenard N.R., Townsend R.L., Patterson L.M., Sigalet D.L., Berthoud H.R. Meal patterns, satiety, and food choice in a rat model of Roux-en-Y gastric bypass surgery. Am J Physiol Regul Integr Comp Physiol 2009, 297:R1273-R1282.
14. Bueter M., Miras A.D., Chichger H., Fenske W., Ghatei M.A., Bloom S.R., et al. Alterations of sucrose preference after Roux-en-Y gastric bypass. Physiol Behav 2011, 104:709-721.
15. Hajnal A., Kovacs P., Ahmed T., Meirelles K., Lynch C.J., Cooney R.N. Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats. Am J Physiol Gastrointest Liver Physiol 2010, 299:G967-G979.
16. Bueter M., Lowenstein C., Olbers T., Wang M., Cluny N.L., Bloom S.R., et al. Gastric bypass increases energy expenditure in rats. Gastroenterology 2010, 138:1845-1853.
17. Stylopoulos N., Hoppin A.G., Kaplan L.M. Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats. Obesity (Silver Spring) 2009, 17:1839-1847.
18. Wadden T.A., Foster G.D., Letizia K.A., Mullen J.L. Long-term effects of dieting on resting metabolic rate in obese outpatients. JAMA 1990, 264:707-711.
19. Shin A.C., Zheng H., Townsend R.L., Sigalet D.L., Berthoud H.R. Meal-induced hormone responses in a rat model of Roux-en-Y gastric bypass surgery. Endocrinology 2010, 151:1588-1597.
20. Rubino F., Gagner M., Gentileschi P., Kini S., Fukuyama S., Feng J., et al. The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism. Ann Surg 2004, 240:236-242.
21. Abbott C.R., Monteiro M., Small C.J., Sajedi A., Smith K.L., Parkinson J.R., et al. The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Res 2005, 1044:127-131.
22. Chelikani P.K., Haver A.C., Reidelberger R.D. Intravenous infusion of peptide YY(3-36) potently inhibits food intake in rats. Endocrinology 2005, 146:879-888.
23. Kinzig K.P., D'Alessio D.A., Seeley R.J. The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. J Neurosci 2002, 22:10470-10476.
24. Schick R.R., Zimmermann J.P., Vorm W.T., Schusdziarra V. Peptides that regulate food intake: glucagon-like peptide 1-(7-36) amide acts at lateral and medial hypothalamic sites to suppress feeding in rats. Am J Physiol Regul Integr Comp Physiol 2003, 284:R1427-R1435.
25. Williams D.L., Baskin D.G., Schwartz M.W. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 2009, 150:1680-1687.
26. Osaka T., Endo M., Yamakawa M., Inoue S. Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system. Peptides 2005, 26:1623-1631.
27. Conarello S.L., Li Z., Ronan J., Roy R.S., Zhu L., Jiang G., et al. Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance. Proc Natl Acad Sci U S A 2003, 100:6825-6830.
28. Bueter M., Abegg K., Seyfried F., Lutz T.A., le Roux C.W. Roux-en-Y gastric bypass operation in rats. J Vis Exp 2012, e3940.
29. Wielinga P.Y., Alder B., Lutz T.A. The acute effect of amylin and salmon calcitonin on energy expenditure. Physiol Behav 2007, 91:212-217.
30. Wielinga P.Y., Lowenstein C., Muff S., Munz M., Woods S.C., Lutz T.A. Central amylin acts as an adiposity signal to control body weight and energy expenditure. Physiol Behav 2010, 101:45-52.
31. Nestoridi E., Kvas S., Kucharczyk J., Stylopoulos N. Resting energy expenditure and energetic cost of feeding are augmented after Roux-en-Y gastric bypass in obese mice. Endocrinology 2012, 153:2234-2244.
32. Saeidi N., Nestoridi E., Kucharczyk J., Uygun M.K., Yarmush M.L., Stylopoulos N. Sleeve gastrectomy and Roux-en-Y gastric bypass exhibit differential effects on food preferences, nutrient absorption and energy expenditure in obese rats. Int J Obes (Lond) 2012, 36:1396-1402.
33. Chelikani P.K., Haver A.C., Reidelberger R.D. Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats. Am J Physiol Regul Integr Comp Physiol 2005, 288:R1695-R1706.
34. Lockie S.H., Heppner K.M., Chaudhary N., Chabenne J.R., Morgan D.A., Veyrat-Durebex C., et al. Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling. Diabetes 2012, 61:2753-2762.
35. Ashrafian H., le Roux C.W. Metabolic surgery and gut hormones-a review of bariatric entero-humoral modulation. Physiol Behav 2009, 97:620-631.
36. Laferrere B., Swerdlow N., Bawa B., Arias S., Bose M., Olivan B., et al. Rise of oxyntomodulin in response to oral glucose after gastric bypass surgery in patients with type 2 diabetes. J Clin Endocrinol Metab 2010, 95:4072-4076.
37. le Roux C.W., Borg C., Wallis K., Vincent R.P., Bueter M., Goodlad R., et al. Gut hypertrophy after gastric bypass is associated with increased glucagon-like peptide 2 and intestinal crypt cell proliferation. Ann Surg 2010, 252:50-56.
38. Adams S.H., Lei C., Jodka C.M., Nikoulina S.E., Hoyt J.A., Gedulin B., et al. PYY[3-36] administration decreases the respiratory quotient and reduces adiposity in diet-induced obese mice. J Nutr 2006, 136:195-201.
39. Dakin C.L., Small C.J., Park A.J., Seth A., Ghatei M.A., Bloom S.R. Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats. Am J Physiol Endocrinol Metab 2002, 283:E1173-E1177.
40. Wynne K., Park A.J., Small C.J., Patterson M., Ellis S.M., Murphy K.G., et al. Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial. Diabetes 2005, 54:2390-2395.
41. Liu Y., Zhou Y., Wang Y., Geng D., Liu J. Roux-en-Y gastric bypass-induced improvement of glucose tolerance and insulin resistance in type 2 diabetic rats are mediated by glucagon-like peptide-1. Obes Surg 2011, 21:1424-1431.
42. Taqi E., Wallace L.E., de Heuvel E., Chelikani P.K., Zheng H., Berthoud H.R., et al. The influence of nutrients, biliary-pancreatic secretions, and systemic trophic hormones on intestinal adaptation in a Roux-en-Y bypass model. J Pediatr Surg 2010, 45:987-995.
43. Fenske W.K., Bueter M., Miras A.D., Ghatei M.A., Bloom S.R., le Roux C.W. Exogenous peptide YY3-36 and Exendin-4 further decrease food intake, whereas octreotide increases food intake in rats after Roux-en-Y gastric bypass. Int J Obes (Lond) 2012, 36:379-384.
44. Drucker D.J. Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. Mol Endocrinol 2003, 17:161-171.
45. Tsai C.H., Hill M., Drucker D.J. Biological determinants of intestinotrophic properties of GLP-2 in vivo. Am J Physiol 1997, 272:G662-G668.
46. Tsai C.H., Hill M., Asa S.L., Brubaker P.L., Drucker D.J. Intestinal growth-promoting properties of glucagon-like peptide-2 in mice. Am J Physiol 1997, 273:E77-E84.
47. Cant J.P., McBride B.W., Croom W.J. The regulation of intestinal metabolism and its impact on whole animal energetics. J Anim Sci 1996, 74:2541-2553.
48. Cannon B., Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 2004, 84:277-359.
49. Rothwell N.J., Stock M.J. A role for brown adipose tissue in diet-induced thermogenesis. Obes Res 1997, 5:650-656.
50. Lee P., Greenfield J.R., Ho K.K., Fulham M.J. A critical appraisal of the prevalence and metabolic significance of brown adipose tissue in adult humans. Am J Physiol Endocrinol Metab 2010, 299:E601-E606.
51. Yilmaz Y., Ones T., Purnak T., Ozguven S., Kurt R., Atug O., et al. Association between the presence of brown adipose tissue and non-alcoholic fatty liver disease in adult humans. Aliment Pharmacol Ther 2011, 34:318-323.
52. Hankir M., Bueter M., Gsell W., Seyfried F., Khalil M., Smith K.L., et al. Increased energy expenditure in gastric bypass rats is not caused by activated brown adipose tissue. Obes Facts 2012, 5:349-358.
53. Baraboi E.D., Smith P., Ferguson A.V., Richard D. Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist. Am J Physiol Regul Integr Comp Physiol 2010, 298:R1098-R1110.