Meal-induced hormone responses in a rat model of roux-en-Y gastric bypass surgery

Endocrinology

Volumn 151, Issue 4, 2010, Pages 1588-1597

  Shin, Andrew C ^a   Zheng, Huiyuan ^a   Townsend, R Leigh ^a   Sigalet, David L ^b   Berthoud, Hans Rudolf ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLIN; GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; PEPTIDE YY;

ANIMAL EXPERIMENT; ARTICLE; BODY FAT; CONTROLLED STUDY; FOOD INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HORMONE BLOOD LEVEL; HORMONE RESPONSE; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERLEPTINEMIA; INSULIN SENSITIVITY; INTRAVENOUS CATHETER; LEAN BODY WEIGHT; LIPID DIET; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; ROUX Y ANASTOMOSIS; SHAM PROCEDURE; WEIGHT REDUCTION;

AMYLOID; ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; EATING; GASTRIC BYPASS; GHRELIN; GLUCAGON-LIKE PEPTIDE 1; INSULIN; LEPTIN; MALE; OBESITY; PEPTIDE YY; POSTPRANDIAL PERIOD; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 77950259995     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-1332     Document Type: Article

References (51)

1. Schauer PR, Burguera B, Ikramuddin S, Cottam D, Gourash W, Hamad G, Eid GM, Mattar S, Ramanathan R, Barinas-Mitchel E, Rao RH, Kuller L, Kelley D 2003 Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Ann Surg 238:467-484
2. Wickremesekera K, Miller G, Naotunne TD, Knowles G, Stubbs RS 2005 Loss of insulin resistance after Roux-en-Y gastric bypass surgery: a time course study. Obes Surg 15:474-481
3. Ali MR, Fuller WD, Rasmussen J 2009 Detailed description of early response of metabolic syndrome after laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis 5:346-351
4. Korner J, Bessler M, Cirilo LJ, Conwell IM, Daud A, Restuccia NL, Wardlaw SL 2005 Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulin. J Clin Endocrinol Metab 90:359-365
5. Korner J, Inabnet W, Conwell IM, Taveras C, Daud A, Olivero-Rivera L, Restuccia NL, Bessler M 2006 Differential effects of gastric bypass and banding on circulating gut hormone and leptin levels. Obesity (Silver Spring) 14:1553-1561
6. le Roux CW, Welbourn R, Werling M, Osborne A, Kokkinos A, Laurenius A, Lönroth H, Fändriks L, Ghatei MA, Bloom SR, Olbers T 2007 Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg 246:780-785
7. le Roux CW, Aylwin SJ, Batterham RL, Borg CM, Coyle F, Prasad V, Shurey S, Ghatei MA, Patel AG, Bloom SR 2006 Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters. Ann Surg 243:108-114
8. Borg CM, le Roux CW, Ghatei MA, Bloom SR, Patel AG, Aylwin SJ 2006 Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety. Br J Surg 93:210-215
9. Morínigo R, Moizé V, Musri M, Lacy AM, Navarro S, Marín JL, Delgado S, Casamitjana R, Vidal J 2006 Glucagon-like peptide-1, peptide YY, hunger, and satiety after gastric bypass surgery in morbidly obese subjects. J Clin Endocrinol Metab 91:1735-1740
10. Rodieux F, Giusti V, D'Alessio DA, Suter M, Tappy L 2008 Effects of gastric bypass and gastric banding on glucose kinetics and gut hormone release. Obesity (Silver Spring) 16:298-305
11. Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, Purnell JQ 2002 Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med 346:1623-1630
12. Frühbeck G, Diez-Caballero A, Gil MJ, Montero I, Gómez-Ambrosi J, Salvador J, Cienfuegos JA 2004 The decrease in plasma ghrelin concentrations following bariatric surgery depends on the functional integrity of the fundus. Obes Surg 14:606-612
13. Stoeckli R, Chanda R, Langer I, Keller U 2004 Changes of body weight and plasma ghrelin levels after gastric banding and gastric bypass. Obes Res 12:346-350
14. Meirelles K, Ahmed T, Culnan DM, Lynch CJ, Lang CH, Cooney RN2009 Mechanisms of glucose homeostasis after Roux-en-Y gastric bypass surgery in the obese, insulin-resistant Zucker rat. Ann Surg 249:277-285
15. Strader AD, Vahl TP, Jandacek RJ, Woods SC, D'Alessio DA, Seeley RJ 2005 Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats.Am J Physiol Endocrinol Metab 288:E447-E453
16. Suzuki S, Ramos EJ, Goncalves CG, Chen C, Meguid MM 2005 Changes in GI hormones and their effect on gastric emptying and transit times after Roux-en-Y gastric bypass in rat model. Surgery 138:283-290
17. Guijarro A, Osei-Hyiaman D, Harvey-White J, Kunos G, Suzuki S, Nadtochiy S, Brookes PS, Meguid MM 2008 Sustained weight loss after Roux-en-Y gastric bypass is characterized by down regulation of endocannabinoids and mitochondrial function. Ann Surg 247:779-790
18. Zheng H, Shin AC, Lenard NR, Townsend RL, Patterson LM, Sigalet DL, Berthoud HR 2009 Meal patterns, satiety, and food choice in a rat model of Roux-en-Y gastric bypass surgery. Am J Physiol Regul Integr Comp Physiol 297:R1273-R1282
19. Holst JJ 1994 Glucagonlike peptide 1: a newly discovered gastrointestinal hormone. Gastroenterology 107:1848-1855
20. Trevaskis JL, Coffey T, Cole R, Lei C, Wittmer C, Walsh B, Weyer C, Koda J, Baron AD, Parkes DG, Roth JD 2008 Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms. Endocrinology 149:5679-5687
21. Roth JD, Coffey T, Jodka CM, Maier H, Athanacio JR, Mack CM, Weyer C, Parkes DG 2007 Combination therapy with amylin and peptide YY[3-36] in obese rodents: anorexigenic synergy and weight loss additivity. Endocrinology 148:6054-6061
22. Roth JD, Roland BL, Cole RL, Trevaskis JL, Weyer C, Koda JE, Anderson CM, Parkes DG, Baron AD 2008 Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies. Proc Natl Acad Sci USA 105:7257-7262
23. Künnecke B, Verry P, Bénardeau A, von Kienlin M 2004 Quantitative body composition analysis in awake mice and rats by magnetic resonance relaxometry. Obes Res 12:1604-1615
24. Berthoud HR, Trimble ER, Siegel EG, Bereiter DA, Jeanrenaud B 1980 Cephalic-phase insulin secretion in normal and pancreatic islet-transplanted rats. Am J Physiol 238:E336-E340
25. Wyvell CL, Berridge KC 2000 Intra-accumbens amphetamine increases the conditioned incentive salience of sucrose reward: enhancement of reward "wanting" without enhanced "liking" or response reinforcement. J Neurosci 20:8122-8130
26. Katsuki A, Sumida Y, Gabazza EC, Murashima S, Furuta M, Araki- Sasaki R, Hori Y, Yano Y, Adachi Y 2001 Homeostasis model assessment is a reliable indicator of insulin resistance during follow-up of patients with type 2 diabetes. Diabetes Care 24:362-365
27. Korner J, Bessler M, Inabnet W, Taveras C, Holst JJ 2007 Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding. Surg Obes Relat Dis 3:597-601
28. Laferrère B, Teixeira J, McGinty J, Tran H, Egger JR, Colarusso A, Kovack B, Bawa B, Koshy N, Lee H, Yapp K, Olivan B 2008 Effect of weight loss by gastric bypass surgery versus hypocaloric diet on glucose and incretin levels in patients with type 2 diabetes. J Clin Endocrinol Metab 93:2479-2485
29. Laferrère B, Heshka S,Wang K, Khan Y, McGinty J, Teixeira J, Hart AB, Olivan B 2007 Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes. Diabetes Care 30:1709-1716
30. Toft-Nielsen MB, Madsbad S, Holst JJ 1999 Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. Diabetes Care 22:1137-1143
31. Chelikani PK, Haver AC, Reidelberger RD 2005 Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats. Am J Physiol Regul Integr Comp Physiol 288:R1695-R1706
32. Rüttimann EB, Arnold M, Hillebrand JJ, Geary N, Langhans W 2009 Intrameal hepatic portal and intraperitoneal infusions of glucagon- like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 150:1174-1181
33. Abbott CR, Monteiro M, Small CJ, Sajedi A, Smith KL, Parkinson JR, Ghatei MA, Bloom SR 2005 The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Res 1044:127-131
34. Holst JJ 2007 The physiology of glucagon-like peptide 1. Physiol Rev 87:1409-1439
35. Troy S, Soty M, Ribeiro L, Laval L, Migrenne S, Fioramonti X, Pillot B, Fauveau V, Aubert R, Viollet B, Foretz M, Leclerc J, Duchampt A, Zitoun C, Thorens B, Magnan C, Mithieux G, Andreelli F 2008 Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metab 8:201-211
36. Chelikani PK, Haver AC, Reidelberger RD 2007 Intermittent intraperitoneal infusion of peptide YY(3-36) reduces daily food intake and adiposity in obese rats.Am J Physiol Regul Integr Comp Physiol 293:R39-R46
37. Talsania T, Anini Y, Siu S, Drucker DJ, Brubaker PL 2005 Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology 146:3748-3756
38. Batterham RL, Heffron H, Kapoor S, Chivers JE, Chandarana K, Herzog H, Le Roux CW, Thomas EL, Bell JD, Withers DJ 2006 Critical role for peptide YY in protein-mediated satiation and bodyweight regulation. Cell Metab 4:223-233
39. Roth CL, Enriori PJ, Harz K, Woelfle J, Cowley MA, Reinehr T 2005 Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss. J Clin Endocrinol Metab 90:6386-6391
40. le Roux CW, Batterham RL, Aylwin SJ, Patterson M, Borg CM, Wynne KJ, Kent A, Vincent RP, Gardiner J, Ghatei MA, Bloom SR 2006 Attenuated peptide YY release in obese subjects is associated with reduced satiety. Endocrinology 147:3-8
41. Holdstock C, Zethelius B, Sundbom M, Karlsson FA, Eden Engstrom B 2008 Postprandial changes in gut regulatory peptides in gastric bypass patients. Int J Obes (Lond) 32:1640-1646
42. Mack C, Wilson J, Athanacio J, Reynolds J, Laugero K, Guss S, Vu C, Roth J, Parkes D 2007 Pharmacological actions of the peptide hormone amylin in the long-term regulation of food intake, food preference, and body weight. Am J Physiol Regul Integr Comp Physiol 293:R1855-R1863
43. Lutz TA 2009 Control of food intake and energy expenditure by amylin-therapeutic implications. Int J Obes (Lond) 33(Suppl 1): S24-S27
44. Frühbeck G, Diez Caballero A, Gil MJ 2004 Fundus functionality and ghrelin concentrations after bariatric surgery. N Engl J Med 350:308-309
45. Tritos NA, Mun E, Bertkau A, Grayson R, Maratos-Flier E, Goldfine A 2003 Serum ghrelin levels in response to glucose load in obese subjects post-gastric bypass surgery. Obes Res 11:919-924
46. Stylopoulos N, Davis P, Pettit JD, Rattner DW, Kaplan LM 2005 Changes in serum ghrelin predict weight loss after Roux-en-Y gastric bypass in rats. Surg Endosc 19:942-946
47. Holdstock C, EngströmBE, Ohrvall M, Lind L, Sundbom M, Karlsson FA 2003 Ghrelin and adipose tissue regulatory peptides: effect of gastric bypass surgery in obese humans. J Clin Endocrinol Metab 88:3177-3183
48. Korner J, Inabnet W, Febres G, Conwell IM, McMahon DJ, Salas R, Taveras C, Schrope B, Bessler M 2009 Prospective study of gut hormone and metabolic changes after adjustable gastric banding and Roux-en-Y gastric bypass. Int J Obes (Lond) 33:786-795
49. Cummings DE 2009 Endocrine mechanisms mediating remission of diabetes after gastric bypass surgery. Int J Obes (Lond) 33(Suppl 1):S33-S40
50. Moo TA, Rubino F 2008 Gastrointestinal surgery as treatment for type 2 diabetes. Curr Opin Endocrinol Diabetes Obes 15:153-158
51. Rubino F 2008 Is type 2 diabetes an operable intestinal disease? A provocative yet reasonable hypothesis. Diabetes Care 31(Suppl 2): S290-S296