Intravenous infusion of peptide YY(3-36) potently inhibits food intake in rats

Endocrinology

Volumn 146, Issue 2, 2005, Pages 879-888

  Chelikani, Prasanth K ^b   Haver, Alvin C ^b   Heidelberger, Roger D ^a  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE YY; PEPTIDE YY[3-36]; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEEDING BEHAVIOR; FOOD INTAKE; IMMUNOREACTIVITY; INHIBITION KINETICS; MALE; NONHUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STOMACH EMPTYING;

ANIMALS; DIETARY SUCROSE; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ENTERAL NUTRITION; INFUSIONS, INTRAVENOUS; MALE; PEPTIDE YY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 12344332415     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-1138     Document Type: Article

References (39)

1. Ekman R, Wahlestedt C, Böttcher G, Sundler F, Hakanson R, Panula P 1986 Peptide YY-like immunoreactivity in the central nervous system of the rat. Regul Pept 16:157-168
2. Ekblad E, Sundler F 2002 Distribution of pancreatic polypeptide and peptide YY. Peptides 23:251-261
3. Bottcher G, Ekblad E, Ekman R, Hakanson R, Sundler F 1993 Peptide YY: a neuropeptide in the gut. Immunocytochemical and immunochemical evidence. Neuroscience 55:281-290
4. Bottcher G, Sjoberg J, Ekman R, Hakanson R, Sundler F 1993 Peptide YY in the mammalian pancreas: immunocytochemical localization and immunochemical characterization. Regul Pept 43:115-130
5. Miyachi Y, Jitsuishi W, Miyoshi A, Fujita S, Mizuchi A, Tatemoto K 1986 The distribution of polypeptide YY-like immunoreactivity in rat tissues. Endocrinology 118:2163-2167
6. Lundberg JM, Tatemoto K, Terenius L, Hellstrom PM, Mutt V, Hokfelt T, Hamberger B 1982 Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility. Proc Natl Acad Sci USA 79:4471-4475
7. Laburthe M, Chenut B, Rouyer-Fessard C, Tatemoto K, Couvineau A, Servin A, Amiranoff B 1986 Interaction of peptide YY with rat intestinal epithelial plasma membranes: binding of the radioiodinated peptide. Endocrinology 118:1910-1917
8. Happola O, Wahlestedt C, Ekman R, Soinila S, Panula P, Hakanson R 1990 Peptide YY-like immunoreactivity in sympathetic neurons of the rat. Neuroscience 39:225-230
9. Broome M, Hokfelt T, Terenius L 1985 Peptide YY (PYY)-immunoreactive neurons in the lower brain stem and spinal cord of rat. Acta Physiol Scand 125:349-352
10. Grandt D, Schimiczek M, Struk K, Shively J, Eysselein VE, Goebell H, Reeve Jr JR 1994 Characterization of two forms of pepride YY, PYY(1-36) and PYY(3-36), in the rabbit. Peptides 15:815-820
11. Grandt D, Schimiczek M, Beglinger C, Layer P, Goebell H, Eysselein VE, Reeve Jr JR 1994 Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36. Regul Pept 51:151-159
12. Grandt D, Teyssen S, Schimiczek M, Reeve Jr JR, Feth F, Rascher W, Hirche H, Singer MV, Layer P, Goebell H1992 Novel generation of hormone receptor specificity by amino terminal processing of pepride YY. Biochem Biophys Res Commun 186:1299-1306
13. Adrian TE, Ferri GL, Bacarese-Hamilton AJ, Fuessl HS, Polak JM, Bloom SR 1985 Human distribution and release of a putative new gut hormone, pepride YY. Gastroenterology 89:1070-1077
14. Taylor IL 1985 Distribution and release of pepride YY in dog measured by specific radioimmunoassay. Gastroenterology 88:731-737
15. Gehlert DR, Gackenheimer SL 1997 Differential distribution of neuropeptide Y Y1 and Y2 receptors in rat and guinea-pig brains. Neuroscience 76:215-224
16. Dumont Y, Fournier A, St. Pierre S, Quirion R 1996 Autoradiographic distribution of [125I]Leu31,Pro34]PYY and [125I]PYY3-36 binding sites in the rat brain evaluated with two newly developed Y1 and Y2 receptor radioligands. Synapse 22:139-1582
17. Berglund MM, Hipskind PA, Gehlert DR 2003 Recent developments in our understanding of the physiological role of PP-fold peptide receptor subtypes. Exp Biol Med (Maywood) 228:217-244
18. Batterham RL, Cohen MA, Ellis SM, Le Roux CW, Withers DJ, Frost GS, Ghatei MA, Bloom SR 2003 Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 349:941-948
19. Pedersen-Bjergaard U, Host U, Kelbaek H, Schifter S, Rehfeld JF, Faber J, Christensen NJ 1996 Influence of meal composition on postprandial peripheral plasma concentrations of vasoactive peptides in man. Scand J Clin Lab Invest 56:497-503
20. Jin H, Cai L, Lee K, Chang TM, Li P, Wagner D, Chey WY 1993 A physiological role of peptide YY on exocrine pancreatic secretion in rats. Gastroenterology 105:208-215
21. Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, Low MJ, Ghatei MA, Cone RD, Bloom SR 2002 Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 418:650-654
22. Challis BG, Pinnock SB, Coll AP, Carter RN, Dickson SL, O'Rahilly S 2003 Acute effects of PYY3-36 on food intake and hypothalamic neuropeptide expression in the mouse. Biochem Biophys Res Commun 311:915-919
23. Halatchev IG, Ellacott KL, Fan W, Cone RD 2004 Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism. Endocrinology 145:2585-2590
24. Adams SH, Won WB, Schonhoff SE, Leiter AB, Paterniti Jr JR 2004 Effects of PYY[3-36] on short-term food intake in mice are not affected by prevailing plasma ghrelin levels. Endocrinology 145:4967-4975
25. Pittner RA, Moore CX, Bhavsar SP, Gedulin BR, Smith PA, Jodka CM, Parkes DG, Paterniti JR, Srivastava VP, Young AA 2004 Effects of PYY[3-36] in rodent models of diabetes and obesity. Int J Obes Relat Metab Disord 28:963-971
26. Cox JE, Randich A 2004 Enhancement of feeding suppression by PYY(3-36) in rats with area postrema ablations. Peptides 25:985-989
27. Tschop M, Castaneda TR, Joost HG, Thone-Reineke C, Ortmann S, Klaus S, Hagan MM, Chandler PC, Oswald KD, Benoit SC, Seeley RJ, Kinzig KP, Moran TH, Beck-sickinger AG, Koglin N, Rodgers RJ, Blundell JE, Ishii Y, Beattie AH, Holch P, Allison DB, Raun K, Madsen K, Wulff BS, Stidsen CE, Birringer M, Kreuzer OJ, Schindler M, Arndt K, Rudolf K, Mark M, Deng XY, Withcomb DC, Halem H, Taylor J, Dong J, Datta R, Culler M, Craney S, Flora D, Smiley D, Heiman ML 2004 Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature 430:1
28. Chelikani PK, Haver AC, Reidelberger RD 2004 Comparison of the inhibitory effects of PYY(3-36) and PYY(1-36) on gastric emptying in rats. Am J Physiol Regul Integr Comp Physiol 287:R1064-R1070
29. Woltman T, Castellanos D, Reidelberger R1995 Role of cholecystokinin in the anorexia produced by duodenal delivery of oleic acid in rats. Am J Physiol Regul Integr Comp Physiol 269:R1420-R1433
30. Reidelberger RD, Solomon TE 1986 Comparative effects of CCK-8 on feeding, sham feeding, and exocrine pancreatic secretion in rats. Am J Physiol 251: R97-R105
31. Reidelberger RD, Arnelo U, Granqvist L, Permert J 2001 Comparative effects of amylin and cholecystokinin on food intake and gastric emptying in rats. Am J Physiol Regul Integr Comp Physiol 280:R605-R611
32. Heidelberger RD, Kelsey L, Heimann D 2002 Effects of amylin-related peptides on food intake, meal patterns, and gastric emptying in rats. Am J Physiol Regul Integr Comp Physiol 282:R1395-R1404
33. Lluis F, Fujimura M, Gomez G, Salva JA, Greeley Jr GH, Thompson JC 1989 [Cellular localization, half-life, and secretion of peptide YY]. Rev Esp Fisiol 45:377-384 (Spanish)
34. Keire DA, Mannon P, Kobayashi M, Walsh JH, Solomon TE, Reeve Jr JR 2000 Primary structures of PYY, [Pro(34)]PYY, and PYY-(3-36) confer different conformations and receptor selectivity. Am J Physiol Gastrointest Liver Physiol 279:G126-G131
35. Keire DA, Bowers CW, Solomon TE, Reeve Jr JR 2002 Structure and receptor binding of PYY analogs. Peptides 23:305-321
36. Corp ES, McQuade J, Krasniki S, Conze DB 2001 Feeding after fourth ventricular administration of neuropeptide Y receptor agonists in rats. Peptides 22:493-499
37. Parker RM, Herzog H 1999 Regional distribution of Y-receptor subtype mRNAs in rat brain. Eur J Neurosci 11:1431-1448
38. Shaw JL, Gackenheimer SL, Gehlert DR 2003 Functional autoradiography of neuropeptide Y Y1 and Y2 receptor subtypes in rat brain using agonist stimulated [35S]GTPγS binding. J Chem Neuroanat 26:179-193
39. Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, Oliver RL, Millington G, Aparicio SA, Colledge WH, Russ AP, Carlton MB, O'Rahilly S 2004 Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc Natl Acad Sci USA 101:4695-4700