Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters

Annals of Surgery

Volumn 243, Issue 1, 2006, Pages 108-114

  Le Roux, Carel W ^a   Aylwin, Simon J B ^c   Batterham, Rachel L ^b   Borg, Cynthia M ^c   Coyle, Frances ^c   Prasad, Vyas ^a   Shurey, Sandra ^d   Ghatei, Mohammad A ^a   Patel, Ameet G ^c   Bloom, Stephen R ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

^d NORTHWICK PARK HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GASTROINTESTINAL HORMONE; GHRELIN; GLUCAGON LIKE PEPTIDE 1; INSULIN; PANCREAS POLYPEPTIDE; PEPTIDE YY;

ADULT; ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; BARIATRIC SURGERY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GASTRIC BANDING; GLYCEMIC CONTROL; HUMAN; HYPOTHALAMUS; INTESTINE BYPASS; JEJUNOINTESTINAL BYPASS; MALE; METABOLISM; NONHUMAN; OBESITY; POSTPRANDIAL STATE; PRIORITY JOURNAL; RAT; RODENT; ROUX Y ANASTOMOSIS; SATIETY; STOMACH BYPASS; SURGICAL TECHNIQUE; WEIGHT REDUCTION;

ADULT; ANIMALS; APPETITE; BARIATRIC SURGERY; CROSS-SECTIONAL STUDIES; FEMALE; GASTROINTESTINAL HORMONES; GLUCAGON-LIKE PEPTIDE 1; HUMANS; INSULIN; MALE; MODELS, ANIMAL; OBESITY; PANCREATIC POLYPEPTIDE; PEPTIDE HORMONES; PEPTIDE YY; RATS; RATS, WISTAR; WEIGHT LOSS;

EID: 30144444692     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sla.0000183349.16877.84     Document Type: Article

References (47)

1. Kopelman PG. Obesity as a medical problem. Nature. 2000;404:635-643.
2. Kortt MA, Langley PC, Cox ER. A review of cost-of-illness studies on obesity. Clin Ther. 1998;20:772-779.
3. Bray GA, Tartaglia LA. Medicinal strategies in the treatment of obesity. Nature. 2000;404:672-677.
4. Vage V, Solhaug JH, Berstad A, et al. Jejunoileal bypass in the treatment of morbid obesity: a 25-year follow-up study of 36 patients. Obes Surg. 2002;12:312-318.
5. Mitchell JE, Lancaster KL, Burgard MA, et al. Long-term follow-up of patients' status after gastric bypass. Obes Surg. 2001;11:464-468.
6. Craig BM, Tseng DS. Cost-effectiveness of gastric bypass for severe obesity. Am J Med. 2002;113:491-498.
7. Pories WJ, Swanson MS, MacDonald KG, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg. 1995;222:339-350.
8. Pories WJ, MacDonald KG, Jr, Morgan EJ, et al. Surgical treatment of obesity and its effect on diabetes: 10-y follow-up. Am J Clin Nutr. 1992;55(suppl):582-585.
9. Mason EE. Ilial transposition and enteroglucagon/GLP-1 in obesity (and diabetic?) surgery. Obes Surg. 1999;9:223-228.
10. Schauer PR, Burguera B, Ikramuddin S, et al. Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Ann Surg. 2003;238:467-484.
11. Clements RH, Gonzalez QH, Long CI, et al. Hormonal changes after Roux-en Y gastric bypass for morbid obesity and the control of type-II diabetes mellitus. Am Surg. 2004;70:1-4.
12. Cummings DE, Weigle DS, Frayo RS, et al. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med. 2002;346:1623-1630.
13. Atkinson RL, Brent EL. Appetite suppressant activity in plasma of rats after intestinal bypass surgery. Am J Physiol. 1982;243:R60-R64.
14. Rubino F, Marescaux J. Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Ann Surg. 2004;239:1-11.
15. Schwartz MW, Morton GJ. Obesity: keeping hunger at bay. Nature. 2002;418:595-597.
16. Schwartz MW, Woods SC, Porte D Jr, et al. Central nervous system control of food intake. Nature. 2000;404:661-671.
17. Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature. 2000;407:908-913.
18. Wren AM, Seal LJ, Cohen MA, et al. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab. 2001;86:5992.
19. Batterham RL, Cowley MA, Small CJ, et al. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature. 2002;418:650-654.
20. Batterham RL, Cohen MA, Ellis SM, et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med. 2003;349:941-948.
21. Kreymann B, Williams G, Ghatei MA, et al. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet. 1987;2:1300-1304.
22. Farilla L, Bulotta A, Hirshberg B, et al. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology. 2003;144:5149-5158.
23. Gutzwiller JP, Goke B, Drewe J, et al. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut. 1999;44:81-86.
24. Asakawa A, Inui A, Yuzuriha H, et al. Characterization of the effects of pancreatic polypeptide in the regulation of energy balance. Gastroenterology. 2003;124:1325-1336.
25. Batterham RL, Le Roux CW, Cohen MA, et al. Pancreatic polypeptide reduces appetite and food intake in humans. J Clin Endocrinol Metab. 2003;88:3989-3992.
26. Olbers T, Lonroth H, Fagevik-Olsen M, et al. Laparoscopic gastric bypass: development of technique, respiratory function, and long-term outcome. Obes Surg. 2003;13:364-370.
27. Jackson RJ, Davis WB, Macdonald I. The energy values of carbohydrates: should bomb calorimeter data be modified? Proc Nutr Soc. 1977;36:90A.
28. Savage AP, Adrian TE, Carolan G, et al. Effects of peptide YY (PYY) on mouth to caecum intestinal transit time and on the rate of gastric emptying in healthy volunteers. Gut. 1987;28:166-170.
29. Adrian TE, Bloom SR, Bryant MG, et al. Distribution and release of human pancreatic polypeptide. Gut. 1976;17:940-944.
30. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-419.
31. Naslund E, Melin I, Gryback P, et al. Reduced food intake after jejunoileal bypass: a possible association with prolonged gastric emptying and altered gut hormone patterns. Am J Clin Nutr. 1997;66:26-32.
32. Kenler HA, Bvolin RE, Cody RP. Changes in eating behavior after horizontal gastroplasty and Roux-en-Y gastric bypass. Am J Clin Nutr. 1990;52:87-92.
33. Adrian TE, Ferri GL, Bacarese-Hamilton AJ, et al. Human distribution and release of a putative new gut hormone, peptide YY. Gastroenterology. 1985;89:1070-1077.
34. Adrian TE, Savage AP, Fuessl HS, et al. Release of peptide YY (PYY) after resection of small bowel, colon, or pancreas in man. Surgery. 1987;101:715-719.
35. Adrian TE, Savage AP, Bacarese-Hamilton AJ, et al. Peptide YY abnormalities in gastrointestinal diseases. Gastroenterology. 1986;90: 379-384.
36. Imamura M. Effects of surgical manipulation of the intestine on peptide YY and its physiology. Peptides. 2002;23:403-407.
37. Saper CB, Chou TC, Elmquist JK. The need to feed: homeostatic and hedonic control of eating. Neuron. 2002;36:199-211.
38. Sugerman HJ, Londrey GL, Kellum JM, et al. Weight loss with vertical banded gastroplasty and Roux-Y gastric bypass for morbid obesity with selective versus random assignment. Am J Surg. 1989;157:93-102.
39. Ren CJ. Controversies in bariatric surgery: evidence-based discussions on laparoscopic adjustable gastric banding. J Gastrointest Surg. 2004; 8:396-397.
40. Dixon AF, Dixon JB, O'Brien PE. Laparoscopic adjustable gastric banding induces prolonged satiety: a randomized blind crossover study. J Clin Endocrinol Metab. 2005;90:813-819.
41. Rand CS, Macgregor AM, Hankins GC. Eating behavior after gastric bypass surgery for obesity. South Med J. 1987;80:961-964.
42. Halmi KA, Mason E, Falk JR, et al. Appetitive behavior after gastric bypass for obesity. Int J Obes. 1981;5:457-464.
43. Naslund E, Gryback P, Hellstrom PM, et al. Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity. Int J Obes Relat Metab Disord. 1997;21:387-392.
44. Gutzwiller JP, Goke B, Drewe J, et al. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut. 1999;44:81-86.
45. Faraj M, Havel PJ, Phelis S, et al. Plasma acylation-stimulating protein, adiponectin, leptin, and ghrelin before and after weight loss induced by gastric bypass surgery in morbidly obese subjects. J Clin Endocrinol Metab. 2003;88:1594-1602.
46. Aylwin SJB. Gastrointestinal surgery and gut hormones. Curr Opin Endocrinol Diabetes. 2005;12:89-98.
47. Biertho L, Steffen R, Ricklin T, et al. Laparoscopic gastric bypass versus laparoscopic adjustable gastric banding: a comparative study of 1,200 cases. J Am Coll Surg. 2003;197:536-544.