Activation of intracellular matrix metalloproteinase-2 by reactive oxygen-nitrogen species: Consequences and therapeutic strategies in the heart

Archives of Biochemistry and Biophysics

Volumn 540, Issue 1-2, 2013, Pages 82-93

  Jacob Ferreira, Anna L ^a   Schulz, Richard ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Contractile dysfunction; Metalloproteinase; Oxidative stress; Post translational regulation

Indexed keywords

5 ETHOXYMETHOXY N HYDROXY 2 METHYL 4 (4 PHENOXYBENZAMIDO)PENTANAMIDE; CARDIOVASCULAR AGENT; CELL PROTEIN; COLLAGENASE 3; CONNECTIN; CYTOCHROME P450; DOXYCYCLINE; GELATINASE A; GELATINASE B; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEME OXYGENASE; ILOMASTAT; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRILYSIN; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 26; MATRIX METALLOPROTEINASE INHIBITOR; PD 166793; PROTEIN TYROSINE PHOSPHATASE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STROMELYSIN; STROMELYSIN 3; SUPEROXIDE DISMUTASE; TETRACYCLINE; TROPONIN I; TROPONIN T; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; BIOSYNTHESIS; CALCIUM TRANSPORT; CARDIOVASCULAR DISEASE; CELLULAR DISTRIBUTION; CLINICAL TRIAL (TOPIC); ELECTROSTIMULATION; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HEART CONTRACTION; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE RELAXATION; HUMAN; LIPID PEROXIDATION; MEMBRANE DEPOLARIZATION; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTON TRANSPORT; REVIEW; SARCOPLASMIC RETICULUM; UNSPECIFIED SIDE EFFECT;

CONTRACTILE DYSFUNCTION; METALLOPROTEINASE; OXIDATIVE STRESS; POST-TRANSLATIONAL REGULATION;

ANIMALS; ENZYME ACTIVATION; HEART DISEASES; HUMANS; INTRACELLULAR SPACE; MATRIX METALLOPROTEINASE 2; MYOCARDIUM; REACTIVE OXYGEN SPECIES;

EID: 84887118267     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2013.09.019     Document Type: Review

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