Direct inhibition of expressed cardiac L-type Ca2+ channels by S- nitrosothiol nitric oxide donors

Circulation Research

Volumn 81, Issue 5, 1997, Pages 742-752

  Hu, Hai ^a   Chiamvimonvat, Nipavan ^a   Yamagishi, Toshio ^a   Marban, Eduardo ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ca2+ channel; Cysteine; Na+ channel; Nitric oxide; Oxidation

Indexed keywords

8 BROMO CYCLIC GMP; BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; CYCLIC GMP; CYSTEINE; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE DONOR; S NITROSOCYSTEINE; S NITROSOGLUTATHIONE; SODIUM ION;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; XENOPUS LAEVIS;

EID: 0030698179     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.res.81.5.742     Document Type: Article

References (57)

1. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980;288:373-376.
2. Stamler JS, Loscalzo J. Endothelium-derived relaxing factor modulates the atherothrombogenic effects of homocysteine. J Cardiovase Pharmacol. 1992;20(suppl 12):S202-S204.
3. Brady AJ, Warren JB, Poole-Wilson PA, Williams TJ, Harding SE. Nitric oxide attenuates cardiac myocyte contraction. Am J Physiol. 1993;265:H176-H182.
4. Gross WL, Bak MI, Ingwall JS, Arstall MA, Smith TW, Balligand JL, Kelly RA. Nitric oxide inhibits creatine kinase and regulates rat heart contractile reserve. Proc Natl Acad Sci U S A. 1996;93:5604-5609.
5. 2+ current: involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation. J Biol Chem. 1993;268:26286-26295.
6. Ca by carbachol and sodium nitroprusside. Pflugers Arch. 1994;426:419-426.
7. Wahler GM, Dollinger SJ. Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase. Am J Physiol. 1995;268:C45-C54.
8. 2+ current in adult rabbit atrioventricular nodal cells. Circ Res. 1996;78:998-1008.
9. 2+ current in guinea-pig ventricular cells. J Physiol (Lond). 1991;443:387-404.
10. 2+ current in single heart cells. Nature. 1986;323:273-275.
11. Levi RC, Alloatti G, Fischmeister R. Cyclic GMP regulates the Ca-channel current in guinea pig ventricular myocytes. Pflugers Arch. 1989;413:685-687.
12. 2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes. Proc Natl Acad Sci U S A. 1991;88:1197-1201.
13. Kirstein M, Rivet-Bastide M, Hatem S, Benardeau A, Mercadier JJ, Fischmeister R. Nitric oxide regulates the calcium current in isolated human atrial myocytes. J Clin Invest. 1995;95:794-802. Comments.
14. Campbell DL, Stamler JS, Strauss HC. Redox modulation of L-type calcium channels in ferret ventricular myocytes: dual mechanism regulation by nitric oxide and S-nitrosothiols. J Gen Physiol. 1996;108:277-293.
15. Stamler JS, Toone EJ, Lipton SA, Sucher N. (S)NO signals: translocation, regulation, and a consensus motif. Neuron. 1997;18:691-696.
16. Hu H, Marban E. Inhibition of expressed L-type calcium current by nitric oxide donors. Biophys J. 1997;72:A111. Abstract.
17. Perez-Garcia MT, Kamp TJ, Marban E. Functional properties of cardiac L-type calcium channels transiently expressed in HEK293 cells: roles of α1 and β subunits. J Gen Physiol. 1995;105:289-305.
18. Graham FL, van der Eb AJ. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 1973;52:456-467.
19. Marshall J, Molloy R, Moss GW, Howe JR, Hughes TE. The jellyfish green fluorescent protein: a new tool for studying ion channel expression and function. Neuron. 1995;14:211-215.
20. Slish DF, Engle DB, Varadi G, Lotan I, Singer D, Dascal N, Schwartz A. Evidence for the existence of a cardiac specific isoform of the alpha 1 subunit of the voltage dependent calcium channel. FEBS Lett. 1989;250:509-514.
21. Pragnell M, Sakamoto J, Jay SD, Campbell KP. Cloning and tissue-specific expression of the brain calcium channel beta-subunit. FEBS Lett. 1991;291:253-258.
22. Perez-Reyes E, Castellano A, Kim HS, Bertrand P, Baggstrom E, Lacerda AE, Wei XY, Birnbaumer L. Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. J Biol Chem. 1992;267:1792-1797.
23. Ellis SB, Williams ME, Ways NR, Brenner R, Sharp AH, Leung AT, Campbell KP, McKenna E, Koch WJ, Hui A, Schwartz A, Harpold MM. Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel. Science. 1988;241:1661-1664.
24. Singer D, Biel M, Lotan I, Flockerzi V, Hofmann F, Dascal N. The roles of the subunits in the function of the calcium channel. Science. 1991;253:1553-1557.
25. 2+ channels. J Biol Chem. 1991;266:21943-21947.
26. Itagaki K, Koch WJ, Bodi I, Klockner U, Slish DF, Schwartz A. Native-type DHP-sensitive calcium channel currents are produced by cloned rat aortic smooth muscle and cardiac alpha 1 subunits expressed in Xenopus laevis oocytes and are regulated by alpha 2-and beta-subunits. FEBS Lett. 1992;297:221-225.
27. 2+ channel alpha 1 subunit as expressed in mouse L cells. FEBS Lett. 1993;315:167-172.
28. Nishimura S, Takeshima H, Hofmann F, Flockerzi V, Imoto K. Requirement of the calcium channel beta subunit for functional conformation. FEBS Lett. 1993;324:283-286.
29. 1C subunit in a human embryonic kidney cell line. J Physiol. 1996;492:89-96.
30. Gellens ME, George AL Jr, Chen LQ, Chahine M, Horn R, Barchi RL, Kallen RG. Primary structure and functional expression of the human cardiac tetrodotoxin-insensitivc voltage-dependent sodium channel. Proc Natl Acad Sci U S A. 1992;80:554-558.
31. Trimmer JS, Cooperman SS, Tomiko SA, Zhou JY, Crean SM, Boyle MB, Kallen RG, Sheng ZH, Barchi RL, Sigworth FJ, Goodman RH, Agnew WS, Mandel G. Primary structure and functional expression of a mammalian skeletal muscle sodium channel. Neuron. 1989;3:33-49.
32. Isom LL, De Jongh KS, Patton DE, Reber BF, Olford J, Charbonneau H, Walsh K, Goldin AL, Catterall WA. Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. Science. 1992;256:839-842.
33. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 1981;391:85-100.
34. Bean BP. Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state. Proc Natl Acad Sci U S A. 1984;81:6388-6392.
35. + channel revealed by cysteine mutagenesis. Neuron. 1996;16:1037-1047.
36. Davisson RL, Travis MD, Bates JN, Lewis SJ. Hemodynamic effects of L- and D-S-nitrosocysteine in the rat: stereoselective S-nitrosothiol recognition sites. Circ Res. 1996;79:256-262.
37. - donation by S-nitrosothiols: implications for regulation of physiological functions by S-nitrosylation and acceleration of disulfide formation. Arch Biochem Biophys. 1995;318:279-285.
38. Feelisch M, Stamler JS. Donors of nitrogen oxides. In: Feelisch M, Stamler JS, eds. Methods in Nitric Oxide Research. New York, NY: John Wiley & Sons Inc; 1996:69-114.
39. Akabas MM, Stauffer DA, Xu M, Karlin A. Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science. 1992;258:307-310.
40. Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HS, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature. 1993;364:626-632. Comments.
41. Perez-Garcia MT, Chiamvimonvat N, Marban E, Tomaselli GF. Structure of the sodium channel pore revealed by serial cysteine mutagenesis. Proc Natl Acad Sci U S A. 1996;93:300-304.
42. + channels. Circ Res. 1995;76:325-334.
43. Perez-Reyes E, Schneider T. Molecular biology of calcium channels. Kidney Int. 1995;48:1111-1124. Review.
44. Bischof G, Serwold TF, Machen TE. Does nitric oxide regulate capacitative Ca influx in HEK 293 cells? Cell Calcium. 1997;21:135-142.
45. Dinerman JL, Steiner JP, Dawson TM, Dawson V, Snyder SH. Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity. Neuropharmacology. 1994;33:1245-1251.
46. Piriev NI, Yamashita C, Samuel G, Farber DB. Rod photoreccptor cGMP-phosphodiesterase: analysis of alpha and beta subunits expressed in human kidney cells. Proc Natl Acad Sci U S A. 1993;90:9340-9344.
47. Chang FC, Hosey MM. Dihydropyridine and phenylalkylamine receptors associated with cardiac and skeletal muscle calcium channels are structurally different. J Biol Chem. 1988;263:18929-18937.
48. Haase H, Karczewski P, Beckert R, Krause EG. Phosphorylation of the L-type calcium channel beta subunit is involved in beta-adrenergic signal transduction in canine myocardium. FEBS Lett. 1993;335:217-222.
49. Isom LL, De Jongh KS, Catterall WA. Auxiliary subunits of voltage-gated ion channels. Neuron. 1994;12:1183-1194. Review.
50. Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature. 1994;368:850-853.
51. Saville B. A scheme for the colorimetric determination of microgram amounts of thiols. Analyst. 1958;83:671-673.
52. Stamler JS, Feelisch M. Preparation and detection of S-nitrosothiols. In: Feelisch M, Stamler JS, ed. Methods in Nitric Oxide Research. New York, NY: John Wiley & Sons Inc; 1996:521-539.
53. 2+ channels. J Biol Chem. 1995;270:30036-30044.
54. Malinski T, Tana Z, Grunfeld S, Palton S, Kapturczak M, Toniboulian P. Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors. Biochem Biophys Res Commun. 1993;193:1076-1082.
55. Kojda G, Kottenberg K, Nix P, Schlüter KD, Piper HM, Noack E. Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes. Circ Res. 1996;78:91-101.
56. Mohan P, Brutsaert DL, Paulus WJ, Sys SU. Myocardial contractile response to nitric oxide and cGMP. Circulation. 1996;93:1223-1229.
57. Balligand JL, Kelly RA, Marsden PA, Smith TW, Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci U S A. 1993;90:347-351