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Volumn 34, Issue 11, 2013, Pages 521-530

Dendritic cells and other innate determinants of T helper cell polarisation

Author keywords

Adaptive immunity; CD4 T cells; Dendritic cells; Innate immunity; PAMPs; Th cell subtypes

Indexed keywords

CD209 ANTIGEN; EPITOPE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 18; INTERLEUKIN 22; INTERLEUKIN 27; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MUCIN 5AC; PATTERN RECOGNITION RECEPTOR; THYMIC STROMAL LYMPHOPOIETIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 12; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84886951416     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2013.07.006     Document Type: Review
Times cited : (186)

References (106)
  • 1
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki A., Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010, 327:291-295.
    • (2010) Science , vol.327 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 2
    • 77954933984 scopus 로고    scopus 로고
    • The origins of vertebrate adaptive immunity
    • Litman G.W., et al. The origins of vertebrate adaptive immunity. Nat. Rev. Immunol. 2010, 10:543-553.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 543-553
    • Litman, G.W.1
  • 3
    • 79957609041 scopus 로고    scopus 로고
    • Diversity and dialogue in immunity to helminths
    • Allen J.E., Maizels R.M. Diversity and dialogue in immunity to helminths. Nat. Rev. Immunol. 2011, 11:375-388.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 375-388
    • Allen, J.E.1    Maizels, R.M.2
  • 4
    • 58149268052 scopus 로고    scopus 로고
    • Induction, function and regulation of IL-17-producing T cells
    • Mills K.H. Induction, function and regulation of IL-17-producing T cells. Eur. J. Immunol. 2008, 38:2636-2649.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2636-2649
    • Mills, K.H.1
  • 5
    • 1242345130 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells - their induction and role in infection
    • Mills K.H., McGuirk P. Antigen-specific regulatory T cells - their induction and role in infection. Semin. Immunol. 2004, 16:107-117.
    • (2004) Semin. Immunol. , vol.16 , pp. 107-117
    • Mills, K.H.1    McGuirk, P.2
  • 6
    • 0016240723 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. 3. Functional properties in vivo
    • Steinman R.M., et al. Identification of a novel cell type in peripheral lymphoid organs of mice. 3. Functional properties in vivo. J. Exp. Med. 1974, 139:1431-1445.
    • (1974) J. Exp. Med. , vol.139 , pp. 1431-1445
    • Steinman, R.M.1
  • 7
    • 46749117207 scopus 로고    scopus 로고
    • Determination of T-cell fate by dendritic cells
    • Diebold S.S. Determination of T-cell fate by dendritic cells. Immunol. Cell Biol. 2008, 86:389-397.
    • (2008) Immunol. Cell Biol. , vol.86 , pp. 389-397
    • Diebold, S.S.1
  • 8
    • 77957731193 scopus 로고    scopus 로고
    • CD11c depletion severely disrupts Th2 induction and development in vivo
    • Phythian-Adams A.T., et al. CD11c depletion severely disrupts Th2 induction and development in vivo. J. Exp. Med. 2010, 207:2089-2096.
    • (2010) J. Exp. Med. , vol.207 , pp. 2089-2096
    • Phythian-Adams, A.T.1
  • 9
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S., et al. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1
  • 10
    • 84878737123 scopus 로고    scopus 로고
    • + T-cell responses to intestinal commensal bacteria
    • + T-cell responses to intestinal commensal bacteria. Nature 2013, 498:113-117.
    • (2013) Nature , vol.498 , pp. 113-117
    • Hepworth, M.R.1
  • 11
    • 84878659255 scopus 로고    scopus 로고
    • 3+ regulatory T cells and promote airway tolerance
    • 3+ regulatory T cells and promote airway tolerance. J. Exp. Med. 2013, 210:775-788.
    • (2013) J. Exp. Med. , vol.210 , pp. 775-788
    • Soroosh, P.1
  • 12
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann T.R., et al. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 1986, 136:2348-2357.
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1
  • 13
    • 0028918570 scopus 로고
    • + Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor
    • + Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor. J. Exp. Med. 1995, 181:1285-1292.
    • (1995) J. Exp. Med. , vol.181 , pp. 1285-1292
    • Mahon, B.P.1
  • 14
    • 84872761427 scopus 로고    scopus 로고
    • Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii
    • Koblansky A.A., et al. Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii. Immunity 2013, 38:119-130.
    • (2013) Immunity , vol.38 , pp. 119-130
    • Koblansky, A.A.1
  • 15
    • 33847183077 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor signals in innate immune defence
    • Trinchieri G., Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 2007, 7:179-190.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 179-190
    • Trinchieri, G.1    Sher, A.2
  • 16
    • 18244389671 scopus 로고    scopus 로고
    • Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN
    • van Gisbergen K.P., et al. Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN. J. Exp. Med. 2005, 201:1281-1292.
    • (2005) J. Exp. Med. , vol.201 , pp. 1281-1292
    • van Gisbergen, K.P.1
  • 17
    • 84873696767 scopus 로고    scopus 로고
    • + T cells toward distinct T-helper cell subsets
    • + T cells toward distinct T-helper cell subsets. Immunol. Rev. 2013, 252:12-23.
    • (2013) Immunol. Rev. , vol.252 , pp. 12-23
    • Yamane, H.1    Paul, W.E.2
  • 18
    • 84870864876 scopus 로고    scopus 로고
    • + T helper 1 cell differentiation
    • + T helper 1 cell differentiation. Immunity 2012, 37:1091-1103.
    • (2012) Immunity , vol.37 , pp. 1091-1103
    • Groom, J.R.1
  • 19
    • 84861164238 scopus 로고    scopus 로고
    • Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGF-beta
    • Tofukuji S., et al. Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGF-beta. J. Immunol. 2012, 188:4846-4857.
    • (2012) J. Immunol. , vol.188 , pp. 4846-4857
    • Tofukuji, S.1
  • 20
    • 84862540443 scopus 로고    scopus 로고
    • + T-cell polarization in vitro and in vivo
    • + T-cell polarization in vitro and in vivo. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:9977-9982.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 9977-9982
    • Cook, P.C.1
  • 21
    • 0034002472 scopus 로고    scopus 로고
    • The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta 2 subunit
    • Chang J.T., et al. The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta 2 subunit. Eur. J. Immunol. 2000, 30:1113-1119.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1113-1119
    • Chang, J.T.1
  • 22
    • 18444385868 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Immunity 2002, 16:779-790.
    • (2002) Immunity , vol.16 , pp. 779-790
    • Pflanz, S.1
  • 23
    • 49149119535 scopus 로고    scopus 로고
    • Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T Cells
    • Batten M., et al. Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T Cells. J. Immunol. 2008, 180:2752-2756.
    • (2008) J. Immunol. , vol.180 , pp. 2752-2756
    • Batten, M.1
  • 24
    • 84870873399 scopus 로고    scopus 로고
    • Interleukin-27: balancing protective and pathological immunity
    • Hunter C.A., Kastelein R. Interleukin-27: balancing protective and pathological immunity. Immunity 2012, 37:960-969.
    • (2012) Immunity , vol.37 , pp. 960-969
    • Hunter, C.A.1    Kastelein, R.2
  • 25
    • 84856691107 scopus 로고    scopus 로고
    • An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection
    • Chen F., et al. An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection. Nat. Med. 2012, 18:260-266.
    • (2012) Nat. Med. , vol.18 , pp. 260-266
    • Chen, F.1
  • 26
    • 56449088737 scopus 로고    scopus 로고
    • Helminth pathogen cathepsin proteases: it's a family affair
    • Robinson M.W., et al. Helminth pathogen cathepsin proteases: it's a family affair. Trends Biochem. Sci. 2008, 33:601-608.
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 601-608
    • Robinson, M.W.1
  • 27
    • 39449133957 scopus 로고    scopus 로고
    • A mechanism for the initiation of allergen-induced T helper type 2 responses
    • Sokol C.L., et al. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat. Immunol. 2008, 9:310-318.
    • (2008) Nat. Immunol. , vol.9 , pp. 310-318
    • Sokol, C.L.1
  • 28
    • 77953812779 scopus 로고    scopus 로고
    • The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling
    • Tang H., et al. The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat. Immunol. 2010, 11:608-617.
    • (2010) Nat. Immunol. , vol.11 , pp. 608-617
    • Tang, H.1
  • 29
    • 84870262436 scopus 로고    scopus 로고
    • Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor
    • Everts B., et al. Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor. J. Exp. Med. 2012, 209:1753-1767.
    • (2012) J. Exp. Med. , vol.209 , pp. 1753-1767
    • Everts, B.1
  • 30
    • 1842477227 scopus 로고    scopus 로고
    • A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells
    • Dillon S., et al. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J. Immunol. 2004, 172:4733-4743.
    • (2004) J. Immunol. , vol.172 , pp. 4733-4743
    • Dillon, S.1
  • 31
    • 0842343445 scopus 로고    scopus 로고
    • Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses
    • Cervi L., et al. Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses. J. Immunol. 2004, 172:2016-2020.
    • (2004) J. Immunol. , vol.172 , pp. 2016-2020
    • Cervi, L.1
  • 32
    • 0033068180 scopus 로고    scopus 로고
    • - subclasses of dendritic cells direct the development of distinct T helper cells in vivo
    • - subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J. Exp. Med. 1999, 189:587-592.
    • (1999) J. Exp. Med. , vol.189 , pp. 587-592
    • Maldonado-Lopez, R.1
  • 33
    • 0033514364 scopus 로고    scopus 로고
    • Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
    • Pulendran B., et al. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:1036-1041.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 1036-1041
    • Pulendran, B.1
  • 34
    • 67349084096 scopus 로고    scopus 로고
    • IL-33-activated dendritic cells induce an atypical TH2-type response
    • Rank M.A., et al. IL-33-activated dendritic cells induce an atypical TH2-type response. J. Allergy Clin. Immunol. 2009, 123:1047-1054.
    • (2009) J. Allergy Clin. Immunol. , vol.123 , pp. 1047-1054
    • Rank, M.A.1
  • 35
    • 79957571971 scopus 로고    scopus 로고
    • IL-33-activated dendritic cells are critical for allergic airway inflammation
    • Besnard A.G., et al. IL-33-activated dendritic cells are critical for allergic airway inflammation. Eur. J. Immunol. 2011, 41:1675-1686.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1675-1686
    • Besnard, A.G.1
  • 36
    • 27744510433 scopus 로고    scopus 로고
    • TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
    • Ito T., et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J. Exp. Med. 2005, 202:1213-1223.
    • (2005) J. Exp. Med. , vol.202 , pp. 1213-1223
    • Ito, T.1
  • 37
    • 33947597895 scopus 로고    scopus 로고
    • Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils
    • Oh K., et al. Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils. Blood 2007, 109:2921-2927.
    • (2007) Blood , vol.109 , pp. 2921-2927
    • Oh, K.1
  • 38
    • 79956158089 scopus 로고    scopus 로고
    • Genetic analysis of basophil function in vivo
    • Sullivan B.M., et al. Genetic analysis of basophil function in vivo. Nat. Immunol. 2011, 12:527-535.
    • (2011) Nat. Immunol. , vol.12 , pp. 527-535
    • Sullivan, B.M.1
  • 39
    • 77957745031 scopus 로고    scopus 로고
    • Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
    • Hammad H., et al. Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J. Exp. Med. 2010, 207:2097-2111.
    • (2010) J. Exp. Med. , vol.207 , pp. 2097-2111
    • Hammad, H.1
  • 40
    • 80052582016 scopus 로고    scopus 로고
    • TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
    • Siracusa M.C., et al. TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature 2011, 477:229-233.
    • (2011) Nature , vol.477 , pp. 229-233
    • Siracusa, M.C.1
  • 41
    • 84867913372 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin-dependent basophils promote Th2 cytokine responses following intestinal helminth infection
    • Giacomin P.R., et al. Thymic stromal lymphopoietin-dependent basophils promote Th2 cytokine responses following intestinal helminth infection. J. Immunol. 2012, 189:4371-4378.
    • (2012) J. Immunol. , vol.189 , pp. 4371-4378
    • Giacomin, P.R.1
  • 42
    • 68149163162 scopus 로고    scopus 로고
    • The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)
    • Steinfelder S., et al. The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J. Exp. Med. 2009, 206:1681-1690.
    • (2009) J. Exp. Med. , vol.206 , pp. 1681-1690
    • Steinfelder, S.1
  • 43
    • 34447634411 scopus 로고    scopus 로고
    • Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
    • Amsen D., et al. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 2007, 27:89-99.
    • (2007) Immunity , vol.27 , pp. 89-99
    • Amsen, D.1
  • 44
    • 34447642439 scopus 로고    scopus 로고
    • Notch directly regulates Gata3 expression during T helper 2 cell differentiation
    • Fang T.C., et al. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 2007, 27:100-110.
    • (2007) Immunity , vol.27 , pp. 100-110
    • Fang, T.C.1
  • 45
    • 84879243447 scopus 로고    scopus 로고
    • Th17 cell based vaccines in mucosal immunity
    • Kumar P., et al. Th17 cell based vaccines in mucosal immunity. Curr. Opin. Immunol. 2013, 25:373-380.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 373-380
    • Kumar, P.1
  • 46
    • 84865793094 scopus 로고    scopus 로고
    • Immunity to infection in IL-17-deficient mice and humans
    • Cypowyj S., et al. Immunity to infection in IL-17-deficient mice and humans. Eur. J. Immunol. 2012, 42:2246-2254.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 2246-2254
    • Cypowyj, S.1
  • 47
    • 58149311503 scopus 로고    scopus 로고
    • Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta
    • Rowan A.G., et al. Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta. J. Immunol. 2008, 181:4485-4494.
    • (2008) J. Immunol. , vol.181 , pp. 4485-4494
    • Rowan, A.G.1
  • 48
    • 84863393017 scopus 로고    scopus 로고
    • Syk kinase-coupled C-type lectin receptors engage protein kinase C-sigma to elicit Card9 adaptor-mediated innate immunity
    • Strasser D., et al. Syk kinase-coupled C-type lectin receptors engage protein kinase C-sigma to elicit Card9 adaptor-mediated innate immunity. Immunity 2012, 36:32-42.
    • (2012) Immunity , vol.36 , pp. 32-42
    • Strasser, D.1
  • 49
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • Cua D.J., et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003, 421:744-748.
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1
  • 50
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E., et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006, 441:235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1
  • 51
    • 33646560950 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces development of the T(H)17 lineage
    • Mangan P.R., et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006, 441:231-234.
    • (2006) Nature , vol.441 , pp. 231-234
    • Mangan, P.R.1
  • 52
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen M., et al. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006, 24:179-189.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1
  • 53
    • 33745873727 scopus 로고    scopus 로고
    • A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
    • Sutton C., et al. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J. Exp. Med. 2006, 203:1685-1691.
    • (2006) J. Exp. Med. , vol.203 , pp. 1685-1691
    • Sutton, C.1
  • 54
    • 84860241847 scopus 로고    scopus 로고
    • Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta
    • Zielinski C.E., et al. Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature 2012, 484:514-518.
    • (2012) Nature , vol.484 , pp. 514-518
    • Zielinski, C.E.1
  • 55
    • 68649088121 scopus 로고    scopus 로고
    • Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
    • Sutton C.E., et al. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31:331-341.
    • (2009) Immunity , vol.31 , pp. 331-341
    • Sutton, C.E.1
  • 56
    • 79956187649 scopus 로고    scopus 로고
    • Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity
    • Lalor S.J., et al. Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity. J. Immunol. 2011, 186:5738-5748.
    • (2011) J. Immunol. , vol.186 , pp. 5738-5748
    • Lalor, S.J.1
  • 57
    • 66649121678 scopus 로고    scopus 로고
    • An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
    • Aksentijevich I., et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N. Engl. J. Med. 2009, 360:2426-2437.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2426-2437
    • Aksentijevich, I.1
  • 58
    • 77955475968 scopus 로고    scopus 로고
    • NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses
    • Gris D., et al. NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J. Immunol. 2010, 185:974-981.
    • (2010) J. Immunol. , vol.185 , pp. 974-981
    • Gris, D.1
  • 59
    • 66949175347 scopus 로고    scopus 로고
    • A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
    • Meng G., et al. A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses. Immunity 2009, 30:860-874.
    • (2009) Immunity , vol.30 , pp. 860-874
    • Meng, G.1
  • 60
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov I.I., et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009, 139:485-498.
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1
  • 61
    • 77953913586 scopus 로고    scopus 로고
    • Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
    • Wu H.J., et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 2010, 32:815-827.
    • (2010) Immunity , vol.32 , pp. 815-827
    • Wu, H.J.1
  • 62
    • 82255191977 scopus 로고    scopus 로고
    • TLR-dependent T cell activation in autoimmunity
    • Mills K.H. TLR-dependent T cell activation in autoimmunity. Nat. Rev. Immunol. 2011, 11:807-822.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 807-822
    • Mills, K.H.1
  • 63
    • 60549095448 scopus 로고    scopus 로고
    • Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells
    • Veldhoen M., et al. Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J. Exp. Med. 2009, 206:43-49.
    • (2009) J. Exp. Med. , vol.206 , pp. 43-49
    • Veldhoen, M.1
  • 64
    • 84876798411 scopus 로고    scopus 로고
    • Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1
    • Wu C., et al. Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Nature 2013, 496:513-517.
    • (2013) Nature , vol.496 , pp. 513-517
    • Wu, C.1
  • 65
    • 44849129837 scopus 로고    scopus 로고
    • Regulatory T cells in the past and for the future
    • Sakaguchi S. Regulatory T cells in the past and for the future. Eur. J. Immunol. 2008, 38:901-937.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 901-937
    • Sakaguchi, S.1
  • 66
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: friend or foe in immunity to infection?
    • Mills K.H. Regulatory T cells: friend or foe in immunity to infection?. Nat. Rev. Immunol. 2004, 4:841-855.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 841-855
    • Mills, K.H.1
  • 67
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid Y., Rouse B.T. Natural regulatory T cells in infectious disease. Nat. Immunol. 2005, 6:353-360.
    • (2005) Nat. Immunol. , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 68
    • 34547788180 scopus 로고    scopus 로고
    • + regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • + regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med. 2007, 204:1757-1764.
    • (2007) J. Exp. Med. , vol.204 , pp. 1757-1764
    • Coombes, J.L.1
  • 69
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
    • McGuirk P., et al. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J. Exp. Med. 2002, 195:221-231.
    • (2002) J. Exp. Med. , vol.195 , pp. 221-231
    • McGuirk, P.1
  • 70
    • 46949100122 scopus 로고    scopus 로고
    • Adenylate cyclase toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells
    • Hickey F.B., et al. Adenylate cyclase toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells. J. Leukoc. Biol. 2008, 84:234-243.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 234-243
    • Hickey, F.B.1
  • 71
    • 32944463876 scopus 로고    scopus 로고
    • Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance
    • Dillon S., et al. Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. J. Clin. Invest. 2006, 116:916-928.
    • (2006) J. Clin. Invest. , vol.116 , pp. 916-928
    • Dillon, S.1
  • 72
    • 53349108327 scopus 로고    scopus 로고
    • Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis
    • Depaolo R.W., et al. Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis. Cell Host Microbe 2008, 4:350-361.
    • (2008) Cell Host Microbe , vol.4 , pp. 350-361
    • Depaolo, R.W.1
  • 73
    • 0034613767 scopus 로고    scopus 로고
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 2000, 192:1213-1222.
    • (2000) J. Exp. Med. , vol.192 , pp. 1213-1222
    • Jonuleit, H.1
  • 74
    • 79954459308 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family
    • Bour-Jordan H., et al. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family. Immunol. Rev. 2011, 241:180-205.
    • (2011) Immunol. Rev. , vol.241 , pp. 180-205
    • Bour-Jordan, H.1
  • 75
    • 77955634800 scopus 로고    scopus 로고
    • Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine
    • Manicassamy S., et al. Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine. Science 2010, 329:849-853.
    • (2010) Science , vol.329 , pp. 849-853
    • Manicassamy, S.1
  • 76
    • 0030667854 scopus 로고    scopus 로고
    • Interleukin-9 is involved in host protective immunity to intestinal nematode infection
    • Faulkner H., et al. Interleukin-9 is involved in host protective immunity to intestinal nematode infection. Eur. J. Immunol. 1997, 27:2536-2540.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2536-2540
    • Faulkner, H.1
  • 77
    • 0035041265 scopus 로고    scopus 로고
    • Role of IL-9 in the pathophysiology of allergic diseases
    • Soussi-Gounni A., et al. Role of IL-9 in the pathophysiology of allergic diseases. J. Allergy Clin. Immunol. 2001, 107:575-582.
    • (2001) J. Allergy Clin. Immunol. , vol.107 , pp. 575-582
    • Soussi-Gounni, A.1
  • 78
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen M., et al. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat. Immunol. 2008, 9:1341-1346.
    • (2008) Nat. Immunol. , vol.9 , pp. 1341-1346
    • Veldhoen, M.1
  • 79
    • 56349093347 scopus 로고    scopus 로고
    • - effector T cells
    • - effector T cells. Nat. Immunol. 2008, 9:1347-1355.
    • (2008) Nat. Immunol. , vol.9 , pp. 1347-1355
    • Dardalhon, V.1
  • 80
    • 76949102494 scopus 로고    scopus 로고
    • Regulation of IL-9 expression by IL-25 signaling
    • Angkasekwinai P., et al. Regulation of IL-9 expression by IL-25 signaling. Nat. Immunol. 2010, 11:250-256.
    • (2010) Nat. Immunol. , vol.11 , pp. 250-256
    • Angkasekwinai, P.1
  • 81
    • 84881530486 scopus 로고    scopus 로고
    • Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation
    • Mielke L.A., et al. Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation. J. Exp. Med. 2013, 210:1117-1124.
    • (2013) J. Exp. Med. , vol.210 , pp. 1117-1124
    • Mielke, L.A.1
  • 82
    • 77958489808 scopus 로고    scopus 로고
    • Functional biology of the IL-22-IL-22R pathway in regulating immunity and inflammation at barrier surfaces
    • Sonnenberg G.F., et al. Functional biology of the IL-22-IL-22R pathway in regulating immunity and inflammation at barrier surfaces. Adv. Immunol. 2010, 107:1-29.
    • (2010) Adv. Immunol. , vol.107 , pp. 1-29
    • Sonnenberg, G.F.1
  • 83
    • 79952584368 scopus 로고    scopus 로고
    • Recent advances in IL-22 biology
    • Zenewicz L.A., Flavell R.A. Recent advances in IL-22 biology. Int. Immunol. 2011, 23:159-163.
    • (2011) Int. Immunol. , vol.23 , pp. 159-163
    • Zenewicz, L.A.1    Flavell, R.A.2
  • 84
    • 84870876967 scopus 로고    scopus 로고
    • Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria
    • Basu R., et al. Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria. Immunity 2012, 37:1061-1075.
    • (2012) Immunity , vol.37 , pp. 1061-1075
    • Basu, R.1
  • 85
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 2011, 29:621-663.
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 621-663
    • Crotty, S.1
  • 86
    • 84877140255 scopus 로고    scopus 로고
    • T follicular helper cell diversity and plasticity
    • Cannons J.L., et al. T follicular helper cell diversity and plasticity. Trends Immunol. 2013, 34:200-207.
    • (2013) Trends Immunol. , vol.34 , pp. 200-207
    • Cannons, J.L.1
  • 87
    • 84255178198 scopus 로고    scopus 로고
    • Early Th1 cell differentiation is marked by a Tfh cell-like transition
    • Nakayamada S., et al. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity 2011, 35:919-931.
    • (2011) Immunity , vol.35 , pp. 919-931
    • Nakayamada, S.1
  • 88
    • 84856558003 scopus 로고    scopus 로고
    • + polyfunctional T cells that mediate rejection of murine tumors
    • + polyfunctional T cells that mediate rejection of murine tumors. Cancer Res. 2012, 72:581-591.
    • (2012) Cancer Res. , vol.72 , pp. 581-591
    • Marshall, N.A.1
  • 89
    • 77956110338 scopus 로고    scopus 로고
    • Polyfunctional T cells in human tuberculosis
    • Wilkinson K.A., Wilkinson R.J. Polyfunctional T cells in human tuberculosis. Eur. J. Immunol. 2010, 40:2139-2142.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2139-2142
    • Wilkinson, K.A.1    Wilkinson, R.J.2
  • 90
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi H., et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000, 408:740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1
  • 91
    • 84876841020 scopus 로고    scopus 로고
    • Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine
    • Ross P.J., et al. Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine. PLoS Pathog. 2013, 9:e1003264.
    • (2013) PLoS Pathog. , vol.9
    • Ross, P.J.1
  • 92
    • 82255175484 scopus 로고    scopus 로고
    • Vaccines for the twenty-first century society
    • Rappuoli R., et al. Vaccines for the twenty-first century society. Nat. Rev. Immunol. 2011, 11:865-872.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 865-872
    • Rappuoli, R.1
  • 93
    • 37849046096 scopus 로고    scopus 로고
    • TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours
    • Conroy H., et al. TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours. Oncogene 2008, 27:168-180.
    • (2008) Oncogene , vol.27 , pp. 168-180
    • Conroy, H.1
  • 94
    • 44749088349 scopus 로고    scopus 로고
    • Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics
    • Jarnicki A.G., et al. Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics. J. Immunol. 2008, 180:3797-3806.
    • (2008) J. Immunol. , vol.180 , pp. 3797-3806
    • Jarnicki, A.G.1
  • 95
    • 84867736584 scopus 로고    scopus 로고
    • Therapeutic potential of targeting IL-17
    • Jones S.A., et al. Therapeutic potential of targeting IL-17. Nat. Immunol. 2012, 13:1022-1025.
    • (2012) Nat. Immunol. , vol.13 , pp. 1022-1025
    • Jones, S.A.1
  • 96
    • 43449111187 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
    • Leonardi C.L., et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). Lancet 2008, 371:1665-1674.
    • (2008) Lancet , vol.371 , pp. 1665-1674
    • Leonardi, C.L.1
  • 97
    • 43449139402 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
    • Papp K.A., et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet 2008, 371:1675-1684.
    • (2008) Lancet , vol.371 , pp. 1675-1684
    • Papp, K.A.1
  • 98
    • 84883810459 scopus 로고    scopus 로고
    • A small jab - a big effect: nonspecific immunomodulation by vaccines
    • Benn C.S., et al. A small jab - a big effect: nonspecific immunomodulation by vaccines. Trends Immunol. 2013, 10.1016/j.it.2013.04.004.
    • (2013) Trends Immunol.
    • Benn, C.S.1
  • 99
    • 84862683651 scopus 로고    scopus 로고
    • Helper T cell diversity and plasticity
    • Nakayamada S., et al. Helper T cell diversity and plasticity. Curr. Opin. Immunol. 2012, 24:297-302.
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 297-302
    • Nakayamada, S.1
  • 100
    • 79952126441 scopus 로고    scopus 로고
    • Tissue-based class control: the other side of tolerance
    • Matzinger P., Kamala T. Tissue-based class control: the other side of tolerance. Nat. Rev. Immunol. 2011, 11:221-230.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 221-230
    • Matzinger, P.1    Kamala, T.2
  • 101
    • 84872968300 scopus 로고    scopus 로고
    • Innate lymphoid cells - how did we miss them?
    • Walker J.A., et al. Innate lymphoid cells - how did we miss them?. Nat. Rev. Immunol. 2013, 13:75-87.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 75-87
    • Walker, J.A.1
  • 102
    • 84873729246 scopus 로고    scopus 로고
    • + innate lymphoid cells
    • + innate lymphoid cells. Nature 2013, 494:261-265.
    • (2013) Nature , vol.494 , pp. 261-265
    • Klose, C.S.1
  • 103
    • 84876780238 scopus 로고    scopus 로고
    • Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells
    • Fuchs A., et al. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells. Immunity 2013, 38:769-781.
    • (2013) Immunity , vol.38 , pp. 769-781
    • Fuchs, A.1
  • 104
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill D.R., et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 2010, 464:1367-1370.
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1
  • 105
    • 84855917402 scopus 로고    scopus 로고
    • AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch
    • Lee J.S., et al. AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat. Immunol. 2012, 13:144-151.
    • (2012) Nat. Immunol. , vol.13 , pp. 144-151
    • Lee, J.S.1
  • 106
    • 77953802446 scopus 로고    scopus 로고
    • IL-22 defines a novel immune pathway of antifungal resistance
    • De Luca A., et al. IL-22 defines a novel immune pathway of antifungal resistance. Mucosal Immunol. 2010, 3:361-373.
    • (2010) Mucosal Immunol. , vol.3 , pp. 361-373
    • De Luca, A.1


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