Pdx-1 Activates Islet α- and β-Cell Proliferation via a Mechanism Regulated by Transient Receptor Potential Cation Channels 3 and 6 and Extracellular Signal-Regulated Kinases 1 and 2

Molecular and Cellular Biology

Volumn 33, Issue 20, 2013, Pages 4017-4029

  Hayes, Heather L ^a,b   Moss, Larry G ^a,b   Schisler, Jonathan C ^a,c   Haldeman, Jonathan M ^a,b   Zhang, Zhushan ^b   Rosenberg, Paul B ^a,b   Newgard, Christopher B ^a,b   Hohmeier, Hans E ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE 4; HISTONE H2AX; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA; THYMIDINE; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PDX 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6;

ANIMAL CELL; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME PHOSPHORYLATION; GENE CONTROL; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; UPREGULATION;

ADENOVIRIDAE; ANIMALS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENES, REPORTER; GENETIC VECTORS; GLUCAGON-SECRETING CELLS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN-SECRETING CELLS; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRPC CATION CHANNELS;

EID: 84886923440     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00469-13     Document Type: Article

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