-
1
-
-
0030821739
-
Molecular insights into the development of the pancreas
-
Debas H.T. Molecular insights into the development of the pancreas. Am J Surg 174 (1997) 227
-
(1997)
Am J Surg
, vol.174
, pp. 227
-
-
Debas, H.T.1
-
2
-
-
0030927342
-
The beta cell transcription factors and development of the pancreas
-
Sander M., and German M.S. The beta cell transcription factors and development of the pancreas. J Mol Med 75 (1997) 327
-
(1997)
J Mol Med
, vol.75
, pp. 327
-
-
Sander, M.1
German, M.S.2
-
3
-
-
0035115065
-
ARIP cells as a model for pancreatic beta cell growth and development
-
Silver K., and Yao F. ARIP cells as a model for pancreatic beta cell growth and development. Pancreas 22 (2001) 141
-
(2001)
Pancreas
, vol.22
, pp. 141
-
-
Silver, K.1
Yao, F.2
-
4
-
-
0029027780
-
Developmental biology of the pancreas
-
Slack J.M. Developmental biology of the pancreas. Development 121 (1995) 1569
-
(1995)
Development
, vol.121
, pp. 1569
-
-
Slack, J.M.1
-
6
-
-
21744435617
-
Morphogenetic plasticity of adult human pancreatic islets of Langerhans
-
Jamal A.M., Lipsett M., Sladek R., et al. Morphogenetic plasticity of adult human pancreatic islets of Langerhans. Cell Death Differ 12 (2005) 702
-
(2005)
Cell Death Differ
, vol.12
, pp. 702
-
-
Jamal, A.M.1
Lipsett, M.2
Sladek, R.3
-
7
-
-
0033009460
-
The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration
-
Sharma A., Zangen D.H., Reitz P., et al. The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes 48 (1999) 507
-
(1999)
Diabetes
, vol.48
, pp. 507
-
-
Sharma, A.1
Zangen, D.H.2
Reitz, P.3
-
8
-
-
0030065520
-
Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter
-
Bretherton-Watt D., Gore N., and Boam D.S. Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter. Biochem J 313 (1996) 495
-
(1996)
Biochem J
, vol.313
, pp. 495
-
-
Bretherton-Watt, D.1
Gore, N.2
Boam, D.S.3
-
9
-
-
0031007661
-
Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells
-
Carty M.D., Lillquist J.S., Peshavaria M., et al. Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells. J Biol Chem 272 (1997) 11986
-
(1997)
J Biol Chem
, vol.272
, pp. 11986
-
-
Carty, M.D.1
Lillquist, J.S.2
Peshavaria, M.3
-
10
-
-
0029812704
-
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1
-
Serup P., Jensen J., Andersen F.G., et al. Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1. Proc Natl Acad Sci USA 93 (1996) 9015
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9015
-
-
Serup, P.1
Jensen, J.2
Andersen, F.G.3
-
11
-
-
10544239538
-
PDX-1 induces insulin and glucokinase gene expressions in alphaTC1 clone 6 cells in the presence of betacellulin
-
Watada H., Kajimoto Y., Miyagawa J., et al. PDX-1 induces insulin and glucokinase gene expressions in alphaTC1 clone 6 cells in the presence of betacellulin. Diabetes 45 (1996) 1826
-
(1996)
Diabetes
, vol.45
, pp. 1826
-
-
Watada, H.1
Kajimoto, Y.2
Miyagawa, J.3
-
12
-
-
0034042959
-
Islet growth and development in the adult
-
Bonner-Weir S. Islet growth and development in the adult. J Mol Endocrinol 24 (2000) 297
-
(2000)
J Mol Endocrinol
, vol.24
, pp. 297
-
-
Bonner-Weir, S.1
-
13
-
-
0242584873
-
Increased islet apoptosis in Pdx1+/[minus] mice
-
Johnson J.D., Ahmed N.T., Luciani D.S., et al. Increased islet apoptosis in Pdx1+/[minus] mice. J Clin Invest 111 (2003) 1147
-
(2003)
J Clin Invest
, vol.111
, pp. 1147
-
-
Johnson, J.D.1
Ahmed, N.T.2
Luciani, D.S.3
-
14
-
-
0036950665
-
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
-
Kitamura T., Nakae J., Kitamura Y., et al. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J Clin Invest 110 (2002) 1839
-
(2002)
J Clin Invest
, vol.110
, pp. 1839
-
-
Kitamura, T.1
Nakae, J.2
Kitamura, Y.3
-
15
-
-
0034691004
-
Transcription factor expression during pancreatic islet regeneration
-
Kritzik M.R., Krahl T., Good A., et al. Transcription factor expression during pancreatic islet regeneration. Mol Cell Endocrinol 164 (2000) 99
-
(2000)
Mol Cell Endocrinol
, vol.164
, pp. 99
-
-
Kritzik, M.R.1
Krahl, T.2
Good, A.3
-
16
-
-
9644268967
-
PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance
-
Kulkarni R.N., Jhala U.S., Winnay J.N., et al. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Invest 114 (2004) 828
-
(2004)
J Clin Invest
, vol.114
, pp. 828
-
-
Kulkarni, R.N.1
Jhala, U.S.2
Winnay, J.N.3
-
17
-
-
33645241470
-
PDX-1 can repress stimulus-induced activation of the INGAP promoter
-
Taylor-Fishwick D.A., Shi W., Pittenger G.L., et al. PDX-1 can repress stimulus-induced activation of the INGAP promoter. J Endocrinol 188 (2006) 611
-
(2006)
J Endocrinol
, vol.188
, pp. 611
-
-
Taylor-Fishwick, D.A.1
Shi, W.2
Pittenger, G.L.3
-
18
-
-
0034781057
-
Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha
-
Tuttle R.L., Gill N.S., Pugh W., et al. Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha. Nat Med 7 (2001) 1133
-
(2001)
Nat Med
, vol.7
, pp. 1133
-
-
Tuttle, R.L.1
Gill, N.S.2
Pugh, W.3
-
19
-
-
0032908805
-
Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis
-
Kumar U., Sasi R., Suresh S., et al. Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis. Diabetes 48 (1999) 77
-
(1999)
Diabetes
, vol.48
, pp. 77
-
-
Kumar, U.1
Sasi, R.2
Suresh, S.3
-
20
-
-
0033862095
-
Expression of the five different somatostatin receptor subtypes in endocrine cells of the pancreas
-
Portela-Gomes G.M., Stridsberg M., Grimelius L., et al. Expression of the five different somatostatin receptor subtypes in endocrine cells of the pancreas. Appl Immunohistochem Mol Morphol 8 (2000) 126
-
(2000)
Appl Immunohistochem Mol Morphol
, vol.8
, pp. 126
-
-
Portela-Gomes, G.M.1
Stridsberg, M.2
Grimelius, L.3
-
21
-
-
0028314969
-
IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
-
Miller C.P., McGehee Jr. R.E., and Habener J.F. IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J 13 (1994) 1145
-
(1994)
EMBO J
, vol.13
, pp. 1145
-
-
Miller, C.P.1
McGehee Jr., R.E.2
Habener, J.F.3
-
22
-
-
0028203634
-
Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: Mediation by human somatostatin receptor subtypes SSTR1 and SSTR2
-
Buscail L., Delesque N., Esteve J.P., et al. Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: Mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc Natl Acad Sci USA 91 (1994) 2315
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2315
-
-
Buscail, L.1
Delesque, N.2
Esteve, J.P.3
-
23
-
-
0030794303
-
Characterization of the antiproliferative signal mediated by the somatostatin receptor subtype sst5
-
Cordelier P., Esteve J.P., Bousquet C., et al. Characterization of the antiproliferative signal mediated by the somatostatin receptor subtype sst5. Proc Natl Acad Sci USA 94 (1997) 9343
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9343
-
-
Cordelier, P.1
Esteve, J.P.2
Bousquet, C.3
-
24
-
-
2342499960
-
Molecular signaling of somatostatin receptors
-
Lahlou H., Guillermet J., Hortala M., et al. Molecular signaling of somatostatin receptors. Ann NY Acad Sci 1014 (2004) 121
-
(2004)
Ann NY Acad Sci
, vol.1014
, pp. 121
-
-
Lahlou, H.1
Guillermet, J.2
Hortala, M.3
-
26
-
-
0024213731
-
Oncological applications of somatostatin analogues
-
Schally A.V. Oncological applications of somatostatin analogues. Cancer Res 48 (1988) 6977
-
(1988)
Cancer Res
, vol.48
, pp. 6977
-
-
Schally, A.V.1
-
27
-
-
0029959644
-
Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3
-
Sharma K., Patel Y.C., and Srikant C.B. Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3. Mol Endocrinol 10 (1996) 1688
-
(1996)
Mol Endocrinol
, vol.10
, pp. 1688
-
-
Sharma, K.1
Patel, Y.C.2
Srikant, C.B.3
-
28
-
-
4444355388
-
Double-gene ablation of SSTR1 and SSTR5 results in hyperinsulinemia and improved glucose tolerance in mice
-
Wang X.P., Norman M.A., Yang J., et al. Double-gene ablation of SSTR1 and SSTR5 results in hyperinsulinemia and improved glucose tolerance in mice. Surgery 136 (2004) 585
-
(2004)
Surgery
, vol.136
, pp. 585
-
-
Wang, X.P.1
Norman, M.A.2
Yang, J.3
-
29
-
-
27144463634
-
The effect of global SSTR5 gene ablation on the endocrine pancreas and glucose regulation in aging mice
-
Wang X.P., Norman M., Yang J., et al. The effect of global SSTR5 gene ablation on the endocrine pancreas and glucose regulation in aging mice. J Surg Res 129 (2005) 64
-
(2005)
J Surg Res
, vol.129
, pp. 64
-
-
Wang, X.P.1
Norman, M.2
Yang, J.3
-
30
-
-
20444428741
-
SSTR5 ablation in islet results in alterations in glucose homeostasis in mice
-
Wang X.P., Yang J., Norman M.A., et al. SSTR5 ablation in islet results in alterations in glucose homeostasis in mice. FEBS Lett 579 (2005) 3107
-
(2005)
FEBS Lett
, vol.579
, pp. 3107
-
-
Wang, X.P.1
Yang, J.2
Norman, M.A.3
-
31
-
-
33244490284
-
Alterations in glucose homeostasis in SSTR1 gene-ablated mice
-
Wang X.P., Norman M., Yang J., et al. Alterations in glucose homeostasis in SSTR1 gene-ablated mice. Mol Cell Endocrinol 247 (2006) 82
-
(2006)
Mol Cell Endocrinol
, vol.247
, pp. 82
-
-
Wang, X.P.1
Norman, M.2
Yang, J.3
-
32
-
-
12944327377
-
In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells
-
Baeyens L., De B.S., Lardon J., et al. In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells. Diabetologia 48 (2005) 49
-
(2005)
Diabetologia
, vol.48
, pp. 49
-
-
Baeyens, L.1
De, B.S.2
Lardon, J.3
-
33
-
-
0036326210
-
Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factors
-
Zhou J., Pineyro M.A., Wang X., et al. Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factors. J Cell Physiol 192 (2002) 304
-
(2002)
J Cell Physiol
, vol.192
, pp. 304
-
-
Zhou, J.1
Pineyro, M.A.2
Wang, X.3
-
34
-
-
20044388765
-
Tissue MicroArray analyses of pancreatic duodenal homeobox-1 in human cancers
-
Wang X.P., Li Z.J., Magnusson J., et al. Tissue MicroArray analyses of pancreatic duodenal homeobox-1 in human cancers. World J Surg 29 (2005) 334
-
(2005)
World J Surg
, vol.29
, pp. 334
-
-
Wang, X.P.1
Li, Z.J.2
Magnusson, J.3
-
35
-
-
0020636495
-
Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release
-
Bonner-Weir S., Trent D.F., and Weir G.C. Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J Clin Invest 71 (1983) 1544
-
(1983)
J Clin Invest
, vol.71
, pp. 1544
-
-
Bonner-Weir, S.1
Trent, D.F.2
Weir, G.C.3
-
36
-
-
0036323269
-
Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells
-
Abraham E.J., Leech C.A., Lin J.C., et al. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 143 (2002) 3152
-
(2002)
Endocrinology
, vol.143
, pp. 3152
-
-
Abraham, E.J.1
Leech, C.A.2
Lin, J.C.3
-
37
-
-
0041827085
-
Increased PDX-1 expression is associated with outcome in patients with pancreatic cancer
-
Koizumi M., Doi R., Toyoda E., et al. Increased PDX-1 expression is associated with outcome in patients with pancreatic cancer. Surgery 134 (2003) 260
-
(2003)
Surgery
, vol.134
, pp. 260
-
-
Koizumi, M.1
Doi, R.2
Toyoda, E.3
-
38
-
-
4744369833
-
Cell-specific cytotoxicity of human pancreatic adenocarcinoma cells using rat insulin promoter thymidine kinase-directed gene therapy
-
Tirone T.A., Wang X.P., Templeton N.S., et al. Cell-specific cytotoxicity of human pancreatic adenocarcinoma cells using rat insulin promoter thymidine kinase-directed gene therapy. World J Surg 28 (2004) 826
-
(2004)
World J Surg
, vol.28
, pp. 826
-
-
Tirone, T.A.1
Wang, X.P.2
Templeton, N.S.3
-
39
-
-
0036918960
-
Cultured pancreatic ductal cells undergo cell cycle re-distribution and beta-cell-like differentiation in response to glucagon-like peptide-1
-
Bulotta A., Hui H., Anastasi E., et al. Cultured pancreatic ductal cells undergo cell cycle re-distribution and beta-cell-like differentiation in response to glucagon-like peptide-1. J Mol Endocrinol 29 (2002) 347
-
(2002)
J Mol Endocrinol
, vol.29
, pp. 347
-
-
Bulotta, A.1
Hui, H.2
Anastasi, E.3
-
40
-
-
17844362238
-
Growth factor-induced signaling of the pancreatic epithelium
-
Kayali A.G., Stotland A., Gunst K.V., et al. Growth factor-induced signaling of the pancreatic epithelium. J Endocrinol 185 (2005) 45
-
(2005)
J Endocrinol
, vol.185
, pp. 45
-
-
Kayali, A.G.1
Stotland, A.2
Gunst, K.V.3
-
41
-
-
0036134978
-
Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47
-
Qiu Y., Guo M., Huang S., et al. Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. Mol Cell Biol 22 (2002) 412
-
(2002)
Mol Cell Biol
, vol.22
, pp. 412
-
-
Qiu, Y.1
Guo, M.2
Huang, S.3
-
42
-
-
0034032317
-
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
-
Stoffers D.A., Kieffer T.J., Hussain M.A., et al. Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 49 (2000) 741
-
(2000)
Diabetes
, vol.49
, pp. 741
-
-
Stoffers, D.A.1
Kieffer, T.J.2
Hussain, M.A.3
-
43
-
-
0035046251
-
Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism
-
Wang X., Zhou J., Doyle M.E., et al. Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism. Endocrinology 142 (2001) 1820
-
(2001)
Endocrinology
, vol.142
, pp. 1820
-
-
Wang, X.1
Zhou, J.2
Doyle, M.E.3
-
44
-
-
23644438592
-
Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter
-
Docherty H.M., Hay C.W., Ferguson L.A., et al. Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter. Biochem J 389 (2005) 813
-
(2005)
Biochem J
, vol.389
, pp. 813
-
-
Docherty, H.M.1
Hay, C.W.2
Ferguson, L.A.3
-
45
-
-
3843139580
-
Hepatic regeneration and enforced PDX-1 expression accelerate transdifferentiation in liver
-
Koizumi M., Doi R., Toyoda E., et al. Hepatic regeneration and enforced PDX-1 expression accelerate transdifferentiation in liver. Surgery 136 (2004) 449
-
(2004)
Surgery
, vol.136
, pp. 449
-
-
Koizumi, M.1
Doi, R.2
Toyoda, E.3
-
46
-
-
33645883815
-
Gene therapy for diabetes: Reinventing the islet
-
Samson S.L., and Chan L. Gene therapy for diabetes: Reinventing the islet. Trends Endocrinol Metab 17 (2006) 92
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 92
-
-
Samson, S.L.1
Chan, L.2
-
47
-
-
3042785984
-
In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow
-
Tang D.Q., Cao L.Z., Burkhardt B.R., et al. In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow. Diabetes 53 (2004) 1721
-
(2004)
Diabetes
, vol.53
, pp. 1721
-
-
Tang, D.Q.1
Cao, L.Z.2
Burkhardt, B.R.3
-
48
-
-
24144479748
-
Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas
-
Holland A.M., Gonez L.J., Naselli G., et al. Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas. Diabetes 54 (2005) 2586
-
(2005)
Diabetes
, vol.54
, pp. 2586
-
-
Holland, A.M.1
Gonez, L.J.2
Naselli, G.3
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