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Volumn 8, Issue 1, 2013, Pages

Blood-brain-barriers in aging and in Alzheimer's disease

Author keywords

Aging; Alzheimer's disease; Blood brain barrier; Blood cerebrospinal fluid barrier; Cerebrospinal fluid; Choroid plexus

Indexed keywords

AMYLOID PRECURSOR PROTEIN; INSULIN; LEPTIN; TRANSFERRIN;

EID: 84886907892     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-8-38     Document Type: Review
Times cited : (226)

References (101)
  • 2
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ: Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 2001, 81:741-766.
    • (2001) Physiol Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 6
    • 80051762728 scopus 로고    scopus 로고
    • Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle
    • Engelhardt B, Coisne C: Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle. Fluids Barriers CNS 2011, 8:4.
    • (2011) Fluids Barriers CNS , vol.8 , pp. 4
    • Engelhardt, B.1    Coisne, C.2
  • 7
    • 78651063705 scopus 로고    scopus 로고
    • Review: Leucocyte-endothelial cell crosstalk at the blood-brain barrier: A prerequisite for successful immune cell entry to the brain
    • Greenwood J, Heasman SJ, Alvarez JI, Prat A, Lyck R, Engelhardt B: Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain. Neuropathol Appl Neurobiol 2011, 37:24-39.
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 24-39
    • Greenwood, J.1    Heasman, S.J.2    Alvarez, J.I.3    Prat, A.4    Lyck, R.5    Engelhardt, B.6
  • 10
    • 71349085295 scopus 로고    scopus 로고
    • Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-alpha-dependent
    • Liu YJ, Guo DW, Tian L, Shang DS, Zhao WD, Li B, Fang WG, Zhu L, Chen YH: Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-alpha-dependent. Neurobiol Aging 2010, 31:175-188.
    • (2010) Neurobiol Aging , vol.31 , pp. 175-188
    • Liu, Y.J.1    Guo, D.W.2    Tian, L.3    Shang, D.S.4    Zhao, W.D.5    Li, B.6    Fang, W.G.7    Zhu, L.8    Chen, Y.H.9
  • 11
    • 84881550022 scopus 로고    scopus 로고
    • Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain
    • Langlet F, Mullier A, Bouret SG, Prevot V, Dehouck B: Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain. J Comp Neurol 2013, 521:3389-3405.
    • (2013) J Comp Neurol , vol.521 , pp. 3389-3405
    • Langlet, F.1    Mullier, A.2    Bouret, S.G.3    Prevot, V.4    Dehouck, B.5
  • 12
    • 0141620181 scopus 로고    scopus 로고
    • Structural and functional aspects of the blood-brain barrier
    • Begley DJ, Brightman MW: Structural and functional aspects of the blood-brain barrier. Prog Drug Res 2003, 61:39-78.
    • (2003) Prog Drug Res , vol.61 , pp. 39-78
    • Begley, D.J.1    Brightman, M.W.2
  • 13
    • 0021841594 scopus 로고
    • Human blood-brain barrier insulin receptor
    • Pardridge WM, Eisenberg J, Yang J: Human blood-brain barrier insulin receptor. J Neurochem 1985, 44:1771-1778.
    • (1985) J Neurochem , vol.44 , pp. 1771-1778
    • Pardridge, W.M.1    Eisenberg, J.2    Yang, J.3
  • 14
    • 0035092097 scopus 로고    scopus 로고
    • Rapid transferrin efflux from brain to blood across the blood-brain barrier
    • Zhang Y, Pardridge WM: Rapid transferrin efflux from brain to blood across the blood-brain barrier. J Neurochem 2001, 76:1597-1600.
    • (2001) J Neurochem , vol.76 , pp. 1597-1600
    • Zhang, Y.1    Pardridge, W.M.2
  • 15
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic BV: The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008, 57:178-201.
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 17
    • 84875191169 scopus 로고    scopus 로고
    • Transporters of the blood-brain and blood-CSF interfaces in development and in the adult
    • Saunders NR, Daneman R, Dziegielewska KM, Liddelow SA: Transporters of the blood-brain and blood-CSF interfaces in development and in the adult. Mol Aspects Med 2013, 34:742-752.
    • (2013) Mol Aspects Med , vol.34 , pp. 742-752
    • Saunders, N.R.1    Daneman, R.2    Dziegielewska, K.M.3    Liddelow, S.A.4
  • 19
    • 0035151718 scopus 로고    scopus 로고
    • Transport of nutrients across the choroid plexus
    • Segal MB: Transport of nutrients across the choroid plexus. Microsc Res Tech 2001, 52:38-48.
    • (2001) Microsc Res Tech , vol.52 , pp. 38-48
    • Segal, M.B.1
  • 22
    • 0034105064 scopus 로고    scopus 로고
    • How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli
    • Rivest S, Lacroix S, Vallieres L, Nadeau S, Zhang J, Laflamme N: How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli. Proc Soc Exp Biol Med 2000, 223:22-38.
    • (2000) Proc Soc Exp Biol Med , vol.223 , pp. 22-38
    • Rivest, S.1    Lacroix, S.2    Vallieres, L.3    Nadeau, S.4    Zhang, J.5    Laflamme, N.6
  • 23
    • 84873307614 scopus 로고    scopus 로고
    • Neurovascular dysfunction and faulty amyloid beta-peptide clearance in Alzheimer disease
    • Sagare AP, Bell RD, Zlokovic BV: Neurovascular dysfunction and faulty amyloid beta-peptide clearance in Alzheimer disease. Cold Spring Harb Perspect Med 2012, 2:a011452.
    • (2012) Cold Spring Harb Perspect Med , vol.2
    • Sagare, A.P.1    Bell, R.D.2    Zlokovic, B.V.3
  • 24
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
    • Bell RD, Zlokovic BV: Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol 2009, 118:103-113.
    • (2009) Acta Neuropathol , vol.118 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 25
    • 78651084322 scopus 로고    scopus 로고
    • Review: Cerebral microvascular pathology in ageing and neurodegeneration
    • Brown WR, Thore CR: Review: cerebral microvascular pathology in ageing and neurodegeneration. Neuropathol Appl Neurobiol 2011, 37:56-74.
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 56-74
    • Brown, W.R.1    Thore, C.R.2
  • 27
    • 78049279739 scopus 로고    scopus 로고
    • Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
    • Bell RD, Winkler EA, Sagare AP, Singh I, LaRue B, Deane R, Zlokovic BV: Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron 2010, 68:409-427.
    • (2010) Neuron , vol.68 , pp. 409-427
    • Bell, R.D.1    Winkler, E.A.2    Sagare, A.P.3    Singh, I.4    LaRue, B.5    Deane, R.6    Zlokovic, B.V.7
  • 28
    • 80055014830 scopus 로고    scopus 로고
    • Central nervous system pericytes in health and disease
    • Winkler EA, Bell RD, Zlokovic BV: Central nervous system pericytes in health and disease. Nat Neurosci 2011, 14:1398-1405.
    • (2011) Nat Neurosci , vol.14 , pp. 1398-1405
    • Winkler, E.A.1    Bell, R.D.2    Zlokovic, B.V.3
  • 30
    • 1542778656 scopus 로고    scopus 로고
    • Choroid plexus, aging of the brain, and Alzheimer's disease
    • Serot JM, Bene MC, Faure GC: Choroid plexus, aging of the brain, and Alzheimer's disease. Front Biosci 2003, 8:s515-s521.
    • (2003) Front Biosci , vol.8
    • Serot, J.M.1    Bene, M.C.2    Faure, G.C.3
  • 31
    • 0035148720 scopus 로고    scopus 로고
    • Ageing choroid plexus-cerebrospinal fluid system
    • Preston JE: Ageing choroid plexus-cerebrospinal fluid system. Microsc Res Tech 2001, 52:31-37.
    • (2001) Microsc Res Tech , vol.52 , pp. 31-37
    • Preston, J.E.1
  • 32
    • 0033583934 scopus 로고    scopus 로고
    • Biondi ring tangles in the choroid plexus of Alzheimer's disease and normal aging brains: A quantitative study
    • Wen GY, Wisniewski HM, Kascsak RJ: Biondi ring tangles in the choroid plexus of Alzheimer's disease and normal aging brains: a quantitative study. Brain Res 1999, 832:40-46.
    • (1999) Brain Res , vol.832 , pp. 40-46
    • Wen, G.Y.1    Wisniewski, H.M.2    Kascsak, R.J.3
  • 35
    • 84861497648 scopus 로고    scopus 로고
    • A possible role for CSF turnover and choroid plexus in the pathogenesis of late onset Alzheimer's disease
    • Serot JM, Zmudka J, Jouanny P: A possible role for CSF turnover and choroid plexus in the pathogenesis of late onset Alzheimer's disease. J Alzheimers Dis 2012, 30:17-26.
    • (2012) J Alzheimers Dis , vol.30 , pp. 17-26
    • Serot, J.M.1    Zmudka, J.2    Jouanny, P.3
  • 36
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: Ageing and microvascular disease-systematic review and meta-analysis
    • Farrall AJ, Wardlaw JM: Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis. Neurobiol Aging 2009, 30:337-352.
    • (2009) Neurobiol Aging , vol.30 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 37
    • 2542475986 scopus 로고    scopus 로고
    • Clearing amyloid through the blood-brain barrier
    • Zlokovic BV: Clearing amyloid through the blood-brain barrier. J Neurochem 2004, 89:807-811.
    • (2004) J Neurochem , vol.89 , pp. 807-811
    • Zlokovic, B.V.1
  • 39
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers - A decade of discovery
    • Walsh DM, Selkoe DJ: A beta oligomers - a decade of discovery. J Neurochem 2007, 101:1172-1184.
    • (2007) J Neurochem , vol.101 , pp. 1172-1184
    • Walsh, D.M.1    Selkoe, D.J.2
  • 40
    • 84857642949 scopus 로고    scopus 로고
    • The toxic Abeta oligomer and Alzheimer's disease: An emperor in need of clothes
    • Benilova I, Karran E, De Strooper B: The toxic Abeta oligomer and Alzheimer's disease: an emperor in need of clothes. Nat Neurosci 2012, 15:349-357.
    • (2012) Nat Neurosci , vol.15 , pp. 349-357
    • Benilova, I.1    Karran, E.2    De Strooper, B.3
  • 41
  • 46
    • 28044466172 scopus 로고    scopus 로고
    • Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I
    • Carro E, Spuch C, Trejo JL, Antequera D, Torres-Aleman I: Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I. J Neurosci 2005, 25:10884-10893.
    • (2005) J Neurosci , vol.25 , pp. 10884-10893
    • Carro, E.1    Spuch, C.2    Trejo, J.L.3    Antequera, D.4    Torres-Aleman, I.5
  • 48
    • 0000532662 scopus 로고
    • Pre-albumin: A thyroxinebinding protein of human plasma
    • Ingbar SH: Pre-albumin: a thyroxinebinding protein of human plasma. Endocrinology 1958, 63:256-259.
    • (1958) Endocrinology , vol.63 , pp. 256-259
    • Ingbar, S.H.1
  • 49
    • 0022970287 scopus 로고
    • Rat choroid plexus specializes in the synthesis and the secretion of transthyretin (prealbumin). Regulation of transthyretin synthesis in choroid plexus is independent from that in liver
    • Dickson PW, Aldred AR, Marley PD, Bannister D, Schreiber G: Rat choroid plexus specializes in the synthesis and the secretion of transthyretin (prealbumin). Regulation of transthyretin synthesis in choroid plexus is independent from that in liver. J Biol Chem 1986, 261:3475-3478.
    • (1986) J Biol Chem , vol.261 , pp. 3475-3478
    • Dickson, P.W.1    Aldred, A.R.2    Marley, P.D.3    Bannister, D.4    Schreiber, G.5
  • 51
    • 0036910380 scopus 로고    scopus 로고
    • Transthyretin as a thyroid hormone carrier: Function revisited
    • Palha JA: Transthyretin as a thyroid hormone carrier: function revisited. Clin Chem Lab Med 2002, 40:1292-1300.
    • (2002) Clin Chem Lab Med , vol.40 , pp. 1292-1300
    • Palha, J.A.1
  • 53
    • 0028959254 scopus 로고
    • Studies on the metabolism of retinol and retinol-binding protein in transthyretin-deficient mice produced by homologous recombination
    • Wei S, Episkopou V, Piantedosi R, Maeda S, Shimada K, Gottesman ME, Blaner WS: Studies on the metabolism of retinol and retinol-binding protein in transthyretin-deficient mice produced by homologous recombination. J Biol Chem 1995, 270:866-870.
    • (1995) J Biol Chem , vol.270 , pp. 866-870
    • Wei, S.1    Episkopou, V.2    Piantedosi, R.3    Maeda, S.4    Shimada, K.5    Gottesman, M.E.6    Blaner, W.S.7
  • 54
    • 4544227975 scopus 로고    scopus 로고
    • Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro
    • Ono K, Yoshiike Y, Takashima A, Hasegawa K, Naiki H, Yamada M: Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro. Exp Neurol 2004, 189:380-392.
    • (2004) Exp Neurol , vol.189 , pp. 380-392
    • Ono, K.1    Yoshiike, Y.2    Takashima, A.3    Hasegawa, K.4    Naiki, H.5    Yamada, M.6
  • 57
    • 0029063033 scopus 로고
    • Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid
    • Golabek A, Marques MA, Lalowski M, Wisniewski T: Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid. Neurosci Lett 1995, 191:79-82.
    • (1995) Neurosci Lett , vol.191 , pp. 79-82
    • Golabek, A.1    Marques, M.A.2    Lalowski, M.3    Wisniewski, T.4
  • 58
    • 57449086201 scopus 로고    scopus 로고
    • Serum transthyretin levels in senile systemic amyloidosis: Effects of age, gender and ethnicity
    • Buxbaum J, Koziol J, Connors LH: Serum transthyretin levels in senile systemic amyloidosis: effects of age, gender and ethnicity. Amyloid 2008, 15:255-261.
    • (2008) Amyloid , vol.15 , pp. 255-261
    • Buxbaum, J.1    Koziol, J.2    Connors, L.H.3
  • 59
    • 81555232259 scopus 로고    scopus 로고
    • Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?
    • Li X, Buxbaum JN: Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease? Mol Neurodegener 2011, 6:79.
    • (2011) Mol Neurodegener , vol.6 , pp. 79
    • Li, X.1    Buxbaum, J.N.2
  • 71
    • 84870359901 scopus 로고    scopus 로고
    • No diagnostic value of plasma clusterin in Alzheimer's disease
    • Silajdzic E, Minthon L, Bjorkqvist M, Hansson O: No diagnostic value of plasma clusterin in Alzheimer's disease. PLoS ONE 2012, 7:e50237.
    • (2012) PLoS ONE , vol.7
    • Silajdzic, E.1    Minthon, L.2    Bjorkqvist, M.3    Hansson, O.4
  • 72
    • 84885664791 scopus 로고    scopus 로고
    • Clusterin Associates Specifically with Abeta40 in Alzheimer's Disease Brain Tissue
    • 10.1111/bpa.12057
    • Howlett DR, Hortobagyi T, Francis PT: Clusterin Associates Specifically with Abeta40 in Alzheimer's Disease Brain Tissue. Brain Pathol 2013. 10.1111/bpa.12057.
    • (2013) Brain Pathol
    • Howlett, D.R.1    Hortobagyi, T.2    Francis, P.T.3
  • 73
    • 0029920929 scopus 로고    scopus 로고
    • Glycoprotein 330/megalin: Probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers
    • Zlokovic BV, Martel CL, Matsubara E, McComb JG, Zheng G, McCluskey RT, Frangione B, Ghiso J: Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. Proc Natl Acad Sci U S A 1996, 93:4229-4234.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4229-4234
    • Zlokovic, B.V.1    Martel, C.L.2    Matsubara, E.3    McComb, J.G.4    Zheng, G.5    McCluskey, R.T.6    Frangione, B.7    Ghiso, J.8
  • 74
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I regulates brain amyloid-beta levels
    • Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I: Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat Med 2002, 8:1390-1397.
    • (2002) Nat Med , vol.8 , pp. 1390-1397
    • Carro, E.1    Trejo, J.L.2    Gomez-Isla, T.3    LeRoith, D.4    Torres-Aleman, I.5
  • 75
    • 84984766757 scopus 로고    scopus 로고
    • Megalin and cubilin: Multifunctional endocytic receptors
    • Christensen EI, Birn H: Megalin and cubilin: multifunctional endocytic receptors. Nat Rev Mol Cell Biol 2002, 3:256-266.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 256-266
    • Christensen, E.I.1    Birn, H.2
  • 80
    • 67349251479 scopus 로고    scopus 로고
    • Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-beta
    • Michelucci A, Heurtaux T, Grandbarbe L, Morga E, Heuschling P: Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-beta. J Neuroimmunol 2009, 210:3-12.
    • (2009) J Neuroimmunol , vol.210 , pp. 3-12
    • Michelucci, A.1    Heurtaux, T.2    Grandbarbe, L.3    Morga, E.4    Heuschling, P.5
  • 81
    • 77956955758 scopus 로고    scopus 로고
    • The role of microglia in amyloid clearance from the AD brain
    • Lee CY, Landreth GE: The role of microglia in amyloid clearance from the AD brain. J Neural Transm 2010, 117:949-960.
    • (2010) J Neural Transm , vol.117 , pp. 949-960
    • Lee, C.Y.1    Landreth, G.E.2
  • 82
    • 84866773764 scopus 로고    scopus 로고
    • Early cerebrovascular inflammation in a transgenic mouse model of Alzheimer's disease
    • Yu D, Corbett B, Yan Y, Zhang GX, Reinhart P, Cho SJ, Chin J: Early cerebrovascular inflammation in a transgenic mouse model of Alzheimer's disease. Neurobiol Aging 2012, 33:2942-2947.
    • (2012) Neurobiol Aging , vol.33 , pp. 2942-2947
    • Yu, D.1    Corbett, B.2    Yan, Y.3    Zhang, G.X.4    Reinhart, P.5    Cho, S.J.6    Chin, J.7
  • 83
    • 0141819900 scopus 로고    scopus 로고
    • Vascular factors in Alzheimer's disease
    • Kalaria RN: Vascular factors in Alzheimer's disease. Int Psychogeriatr 2003, 15(Suppl 1):47-52.
    • (2003) Int Psychogeriatr , vol.15 , Issue.SUPPL. 1 , pp. 47-52
    • Kalaria, R.N.1
  • 84
    • 78649427539 scopus 로고    scopus 로고
    • Vascular basis for brain degeneration: Faltering controls and risk factors for dementia
    • Kalaria RN: Vascular basis for brain degeneration: faltering controls and risk factors for dementia. Nutr Rev 2010, 68(Suppl 2):S74-S87.
    • (2010) Nutr Rev , vol.68 , Issue.SUPPL. 2
    • Kalaria, R.N.1
  • 86
    • 0035690770 scopus 로고    scopus 로고
    • Inflammatory factors are elevated in brain microvessels in Alzheimer's disease
    • Grammas P, Ovase R: Inflammatory factors are elevated in brain microvessels in Alzheimer's disease. Neurobiol Aging 2001, 22:837-842.
    • (2001) Neurobiol Aging , vol.22 , pp. 837-842
    • Grammas, P.1    Ovase, R.2
  • 87
    • 0036098247 scopus 로고    scopus 로고
    • Cerebrovascular transforming growth factor-beta contributes to inflammation in the Alzheimer's disease brain
    • Grammas P, Ovase R: Cerebrovascular transforming growth factor-beta contributes to inflammation in the Alzheimer's disease brain. Am J Pathol 2002, 160:1583-1587.
    • (2002) Am J Pathol , vol.160 , pp. 1583-1587
    • Grammas, P.1    Ovase, R.2
  • 88
    • 33646014454 scopus 로고    scopus 로고
    • Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: Implications for disease pathogenesis
    • Grammas P, Samany PG, Thirumangalakudi L: Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: implications for disease pathogenesis. J Alzheimers Dis 2006, 9:51-58.
    • (2006) J Alzheimers Dis , vol.9 , pp. 51-58
    • Grammas, P.1    Samany, P.G.2    Thirumangalakudi, L.3
  • 89
    • 84877586983 scopus 로고    scopus 로고
    • Increased blood-brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model
    • Takeda S, Sato N, Ikimura K, Nishino H, Rakugi H, Morishita R: Increased blood-brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model. Neurobiol Aging 2013, 34:2064-2070.
    • (2013) Neurobiol Aging , vol.34 , pp. 2064-2070
    • Takeda, S.1    Sato, N.2    Ikimura, K.3    Nishino, H.4    Rakugi, H.5    Morishita, R.6
  • 92
    • 0034684233 scopus 로고    scopus 로고
    • Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse
    • Kjeldsen L, Cowland JB, Borregaard N: Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse. Biochim Biophys Acta 2000, 1482:272-283.
    • (2000) Biochim Biophys Acta , vol.1482 , pp. 272-283
    • Kjeldsen, L.1    Cowland, J.B.2    Borregaard, N.3
  • 97
    • 79955683626 scopus 로고    scopus 로고
    • Increased plasma levels of lipocalin 2 in mild cognitive impairment
    • Choi J, Lee HW, Suk K: Increased plasma levels of lipocalin 2 in mild cognitive impairment. J Neurol Sci 2011, 305:28-33.
    • (2011) J Neurol Sci , vol.305 , pp. 28-33
    • Choi, J.1    Lee, H.W.2    Suk, K.3
  • 100
    • 81055126115 scopus 로고    scopus 로고
    • Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation
    • Mucha M, Skrzypiec AE, Schiavon E, Attwood BK, Kucerova E, Pawlak R: Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation. Proc Natl Acad Sci U S A 2011, 108:18436-18441.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 18436-18441
    • Mucha, M.1    Skrzypiec, A.E.2    Schiavon, E.3    Attwood, B.K.4    Kucerova, E.5    Pawlak, R.6
  • 101
    • 84876050401 scopus 로고    scopus 로고
    • Stress-induced lipocalin-2 controls dendritic spine formation and neuronal activity in the amygdala
    • Skrzypiec AE, Shah RS, Schiavon E, Baker E, Skene N, Pawlak R, Mucha M: Stress-induced lipocalin-2 controls dendritic spine formation and neuronal activity in the amygdala. PLoS ONE 2013, 8:e61046.
    • (2013) PLoS ONE , vol.8
    • Skrzypiec, A.E.1    Shah, R.S.2    Schiavon, E.3    Baker, E.4    Skene, N.5    Pawlak, R.6    Mucha, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.