Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro

Experimental Neurology

Volumn 189, Issue 2, 2004, Pages 380-392

  Ono, Kenjiro ^a   Yoshiike, Yuji ^b   Takashima, Akihiko ^b   Hasegawa, Kazuhiro ^c,d   Naiki, Hironobu ^c,d   Yamada, Masahito ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c UNIVERSITY OF FUKUI   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

amyloid fibrils; Alzheim's disease; Cytotoxicity; Electron microscopy; Thioflavin T; Vitamin A

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; ASCORBIC ACID; BETA CAROTENE; PYRIDOXINE; RETINAL; RETINOIC ACID; RETINOL; RIBOFLAVIN; THIOFLAVINE;

ALZHEIMER DISEASE; ARTICLE; DOSE RESPONSE; DRUG POTENCY; ELECTRON MICROSCOPY; EMBRYO; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; KIDNEY CELL; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANTIOXIDANTS; BETA CAROTENE; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KINETICS; MICROSCOPY, ELECTRON; MOLECULAR STRUCTURE; NEUROFIBRILS; RETINALDEHYDE; THIAZOLES; TRETINOIN; VITAMIN A; VITAMINS;

EID: 4544227975     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.05.035     Document Type: Article

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