메뉴 건너뛰기




Volumn 28, Issue 11, 2013, Pages 2392-2399

Metabolic regulation of osteoclast differentiation and function

Author keywords

BIOENERGETICS; BIOSYNTHESIS; GLUTAMINOLYSIS; GLYCOLYSIS; OSTEOCLAST

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ADENOSINE PHOSPHATE; CATHEPSIN K; GLUCOSE TRANSPORTER 1; GLUTAMINASE; GLUTAMINE; HEXOKINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTATE DEHYDROGENASE; MAMMALIAN TARGET OF RAPAMYCIN; MYC PROTEIN; PYRUVATE KINASE; VASCULOTROPIN;

EID: 84886859944     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1976     Document Type: Article
Times cited : (177)

References (42)
  • 1
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G, Wagner EF., Reaching a genetic and molecular understanding of skeletal development. Dev Cell. 2002; 2 (4): 389-406.
    • (2002) Dev Cell. , vol.2 , Issue.4 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 2
    • 34447132814 scopus 로고    scopus 로고
    • Skeletal remodeling in health and disease
    • Zaidi M., Skeletal remodeling in health and disease. Nat Med. 2007; 13 (7): 791-801.
    • (2007) Nat Med. , vol.13 , Issue.7 , pp. 791-801
    • Zaidi, M.1
  • 3
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum SL, Ross FP., Genetic regulation of osteoclast development and function. Nat Rev Genet. 2003; 4 (8): 638-49.
    • (2003) Nat Rev Genet. , vol.4 , Issue.8 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 4
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL., Osteoclast differentiation and activation. Nature. 2003; 423 (6937): 337-42.
    • (2003) Nature. , vol.423 , Issue.6937 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 5
    • 33947583822 scopus 로고    scopus 로고
    • Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
    • Takayanagi H., Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol. 2007; 7 (4): 292-304.
    • (2007) Nat Rev Immunol. , vol.7 , Issue.4 , pp. 292-304
    • Takayanagi, H.1
  • 9
    • 0033635249 scopus 로고    scopus 로고
    • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability
    • Rathmell JC, Vander Heiden MG, Harris MH, Frauwirth KA, Thompson CB., In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Mol Cell. 2000; 6 (3): 683-92.
    • (2000) Mol Cell. , vol.6 , Issue.3 , pp. 683-692
    • Rathmell, J.C.1    Vander Heiden, M.G.2    Harris, M.H.3    Frauwirth, K.A.4    Thompson, C.B.5
  • 12
    • 0034907875 scopus 로고    scopus 로고
    • Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models
    • Chow DC, Wenning LA, Miller WM, Papoutsakis ET., Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models. Biophys J. 2001; 81 (2): 685-96.
    • (2001) Biophys J. , vol.81 , Issue.2 , pp. 685-696
    • Chow, D.C.1    Wenning, L.A.2    Miller, W.M.3    Papoutsakis, E.T.4
  • 14
    • 0029888341 scopus 로고    scopus 로고
    • Cloning and functional characterization of a system ASC-like Na + -dependent neutral amino acid transporter
    • Utsunomiya-Tate N, Endou H, Kanai Y., Cloning and functional characterization of a system ASC-like Na + -dependent neutral amino acid transporter. J Biol Chem. 1996; 271 (25): 14883-90.
    • (1996) J Biol Chem. , vol.271 , Issue.25 , pp. 14883-14890
    • Utsunomiya-Tate, N.1    Endou, H.2    Kanai, Y.3
  • 16
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB., The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 2008; 7 (1): 11-20.
    • (2008) Cell Metab. , vol.7 , Issue.1 , pp. 11-20
    • Deberardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 20
    • 0142057146 scopus 로고    scopus 로고
    • Low molecular weight inhibitors of Myc-Max interaction and function
    • Yin X, Giap C, Lazo JS, Prochownik EV., Low molecular weight inhibitors of Myc-Max interaction and function. Oncogene. 2003; 22 (40): 6151-9.
    • (2003) Oncogene. , vol.22 , Issue.40 , pp. 6151-6159
    • Yin, X.1    Giap, C.2    Lazo, J.S.3    Prochownik, E.V.4
  • 21
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • Zoncu R, Efeyan A, Sabatini DM., mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol. 2011; 12 (1): 21-35.
    • (2011) Nat Rev Mol Cell Biol. , vol.12 , Issue.1 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 22
    • 80155142474 scopus 로고    scopus 로고
    • Rapamycin passes the torch: A new generation of mTOR inhibitors
    • Benjamin D, Colombi M, Moroni C, Hall MN., Rapamycin passes the torch: a new generation of mTOR inhibitors. Nat Rev Drug Discov. 2011; 10 (11): 868-80.
    • (2011) Nat Rev Drug Discov. , vol.10 , Issue.11 , pp. 868-880
    • Benjamin, D.1    Colombi, M.2    Moroni, C.3    Hall, M.N.4
  • 25
    • 77951768486 scopus 로고    scopus 로고
    • Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
    • Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM., Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010; 141 (2): 290-303.
    • (2010) Cell. , vol.141 , Issue.2 , pp. 290-303
    • Sancak, Y.1    Bar-Peled, L.2    Zoncu, R.3    Markhard, A.L.4    Nada, S.5    Sabatini, D.M.6
  • 28
    • 0001221508 scopus 로고
    • On respiratory impairment in cancer cells
    • Warburg O., On respiratory impairment in cancer cells. Science. 1956; 124 (3215): 269-70.
    • (1956) Science. , vol.124 , Issue.3215 , pp. 269-270
    • Warburg, O.1
  • 29
    • 34548014737 scopus 로고    scopus 로고
    • Revving the engine: Signal transduction fuels T cell activation
    • Jones RG, Thompson CB., Revving the engine: signal transduction fuels T cell activation. Immunity. 2007; 27 (2): 173-8.
    • (2007) Immunity. , vol.27 , Issue.2 , pp. 173-178
    • Jones, R.G.1    Thompson, C.B.2
  • 30
    • 0035499204 scopus 로고    scopus 로고
    • Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival
    • Schipani E, Ryan HE, Didrickson S, Kobayashi T, Knight M, Johnson RS., Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev. 2001; 15 (21): 2865-76.
    • (2001) Genes Dev. , vol.15 , Issue.21 , pp. 2865-2876
    • Schipani, E.1    Ryan, H.E.2    Didrickson, S.3    Kobayashi, T.4    Knight, M.5    Johnson, R.S.6
  • 33
    • 66849097919 scopus 로고    scopus 로고
    • Acute hypoxia and osteoclast activity: A balance between enhanced resorption and increased apoptosis
    • Knowles HJ, Athanasou NA., Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis. J Pathol. 2009; 218 (2): 256-64.
    • (2009) J Pathol. , vol.218 , Issue.2 , pp. 256-264
    • Knowles, H.J.1    Athanasou, N.A.2
  • 35
    • 35848940094 scopus 로고    scopus 로고
    • Osteoclast precursors display dynamic metabolic shifts toward accelerated glucose metabolism at an early stage of RANKL-stimulated osteoclast differentiation
    • Kim JM, Jeong D, Kang HK, Jung SY, Kang SS, Min BM., Osteoclast precursors display dynamic metabolic shifts toward accelerated glucose metabolism at an early stage of RANKL-stimulated osteoclast differentiation. Cell Physiol Biochem. 2007; 20 (6): 935-46.
    • (2007) Cell Physiol Biochem. , vol.20 , Issue.6 , pp. 935-946
    • Kim, J.M.1    Jeong, D.2    Kang, H.K.3    Jung, S.Y.4    Kang, S.S.5    Min, B.M.6
  • 37
    • 0036708160 scopus 로고    scopus 로고
    • Transcription from the tartrate-resistant acid phosphatase promoter is negatively regulated by the Myc oncoprotein
    • Daumer KM, Taparowsky EJ, Hall DJ, Steinbeck MJ., Transcription from the tartrate-resistant acid phosphatase promoter is negatively regulated by the Myc oncoprotein. J Bone Miner Res. 2002; 17 (9): 1701-9.
    • (2002) J Bone Miner Res. , vol.17 , Issue.9 , pp. 1701-1709
    • Daumer, K.M.1    Taparowsky, E.J.2    Hall, D.J.3    Steinbeck, M.J.4
  • 38
    • 13544249982 scopus 로고    scopus 로고
    • Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors
    • Sugatani T, Hruska KA., Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors. J Biol Chem. 2005; 280 (5): 3583-9.
    • (2005) J Biol Chem. , vol.280 , Issue.5 , pp. 3583-3589
    • Sugatani, T.1    Hruska, K.A.2
  • 39
    • 0141893375 scopus 로고    scopus 로고
    • M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase
    • Glantschnig H, Fisher JE, Wesolowski G, Rodan GA, Reszka AA., M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase. Cell Death Differ. 2003; 10 (10): 1165-77.
    • (2003) Cell Death Differ. , vol.10 , Issue.10 , pp. 1165-1177
    • Glantschnig, H.1    Fisher, J.E.2    Wesolowski, G.3    Rodan, G.A.4    Reszka, A.A.5
  • 40
    • 77951255954 scopus 로고    scopus 로고
    • Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: Implications for lytic bone diseases
    • Smink JJ, Leutz A., Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: implications for lytic bone diseases. J Mol Med (Berl). 2010; 88 (3): 227-33.
    • (2010) J Mol Med (Berl). , vol.88 , Issue.3 , pp. 227-233
    • Smink, J.J.1    Leutz, A.2
  • 42
    • 77955351696 scopus 로고    scopus 로고
    • Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis
    • Cejka D, Hayer S, Niederreiter B, Sieghart W, Fuereder T, Zwerina J, Schett G., Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis. Arthritis Rheum. 2010; 62 (8): 2294-302.
    • (2010) Arthritis Rheum. , vol.62 , Issue.8 , pp. 2294-2302
    • Cejka, D.1    Hayer, S.2    Niederreiter, B.3    Sieghart, W.4    Fuereder, T.5    Zwerina, J.6    Schett, G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.