-
1
-
-
0021280147
-
Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc
-
Torres, C.-R. and Hart, G. W. (1984) Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc. J. Biol. Chem. 259, 3308-3317 (Pubitemid 14130544)
-
(1984)
Journal of Biological Chemistry
, vol.259
, Issue.5
, pp. 3308-3317
-
-
Torres, C.-R.1
Hart, G.W.2
-
2
-
-
0029049198
-
C-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas
-
Chou, T.-Y., Hart, G. W. and Dang, C. V. (1995) c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J. Biol. Chem. 270, 18961-18965
-
(1995)
J. Biol. Chem
, vol.270
, pp. 18961-18965
-
-
Chou, T.-Y.1
Hart, G.W.2
Dang, C.V.3
-
3
-
-
0023037076
-
The subcellular distribution of terminal N-acetylglucosamine moieties. Localization of a novel protein-saccharidie linkage, O-linked GlcNAc
-
Holt, G. D. and Hart, G. W. (1986) The subcellular distribution of terminal N-acetylglucosamine moieties. Localization of a novel protein-saccharide linkage, O-linked GlcNAc. J. Biol. Chem. 261, 8049-8057 (Pubitemid 17208742)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.17
, pp. 8049-8057
-
-
Holt, G.D.1
Hart, G.W.2
-
4
-
-
0023225084
-
Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine
-
DOI 10.1083/jcb.104.5.1157
-
Holt, G. D., Snow, C. M., Senior, A., Haltiwanger, R. S., Gerace, L. and Hart, G. W. (1987) Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine. J. Cell Biol. 104, 1157-64 (Pubitemid 17084473)
-
(1987)
Journal of Cell Biology
, vol.104
, Issue.5
, pp. 1157-1164
-
-
Holt, G.D.1
Snow, C.M.2
Senior, A.3
-
5
-
-
79959381299
-
Cross talk between O-GlcNAcylation and phosphorylation: Roles in signaling, transcription, and chronic disease
-
Hart, G. W., Slawson, C., Ramirez-Correa, G. and Lagerlof, O. (2011) Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu. Rev. Biochem. 80, 825-858
-
(2011)
Annu. Rev. Biochem
, vol.80
, pp. 825-858
-
-
Hart, G.W.1
Slawson, C.2
Ramirez-Correa, G.3
Lagerlof, O.4
-
6
-
-
84873350431
-
Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry
-
Hahne, H., Sobotzki, N., Nyberg, T., Helm, D., Borodkin, V. S., van Aalten, D. M. F., Agnew, B. and Kuster, B. (2013) Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry. J. Proteome Res. 12, 927-936
-
(2013)
J. Proteome Res
, vol.12
, pp. 927-936
-
-
Hahne, H.1
Sobotzki, N.2
Nyberg, T.3
Helm, D.4
Borodkin, V.S.5
Van Aalten, D.M.F.6
Agnew, B.7
Kuster, B.8
-
7
-
-
84884323220
-
O-GlcNAcomics: Revealing roles of O-GlcNAcylation in disease mechanisms and development of potential diagnostics
-
doi:10.1002/prca.201300001
-
Copeland, R. J., Han, G. and Hart, G. W. (2013) O-GlcNAcomics: revealing roles of O-GlcNAcylation in disease mechanisms and development of potential diagnostics. Proteomics Clin. Appl., doi:10.1002/prca.201300001
-
(2013)
Proteomics Clin. Appl.
-
-
Copeland, R.J.1
Han, G.2
Hart, G.W.3
-
8
-
-
30744474699
-
Global identification of O-GlcNAc-modified proteins
-
DOI 10.1021/ac051207j
-
Nandi, A., Sprung, R., Barma, D. K., Zhao, Y., Kim, S. C., Falck, J. R. and Zhao, Y. (2006) Global identification of O-GlcNAc-modified proteins. Anal. Chem. 78, 452-458 (Pubitemid 43100377)
-
(2006)
Analytical Chemistry
, vol.78
, Issue.2
, pp. 452-458
-
-
Nandi, A.1
Sprung, R.2
Barma, D.K.3
Zhao, Y.4
Kim, S.C.5
Falck, J.R.6
Zhao, Y.7
-
9
-
-
62349091636
-
Molecular characterization of nucleocytosolic O-GlcNAc transferases of Giardia lambliaand Cryptosporidium parvum
-
Banerjee, S., Robbins, P. W. and Samuelson, J. (2009) Molecular characterization of nucleocytosolic O-GlcNAc transferases of Giardia lambliaand Cryptosporidium parvum. Glycobiology 19, 331-336
-
(2009)
Glycobiology
, vol.19
, pp. 331-336
-
-
Banerjee, S.1
Robbins, P.W.2
Samuelson, J.3
-
10
-
-
0024516198
-
Glycosylation of chromosomal proteins: Localization of O-linked N-acetylglucosamine in Drosophila chromatin
-
DOI 10.1016/0092-8674(89)90962-8
-
Kelly, W. G. and Hart, G. W. (1989) Glycosylation of chromosomal proteins: localization of O-linked N-acetylglucosamine in Drosophila chromatin. Cell 57, 243-251 (Pubitemid 19112364)
-
(1989)
Cell
, vol.57
, Issue.2
, pp. 243-251
-
-
Kelly, W.G.1
Hart, G.W.2
-
11
-
-
0036021405
-
Two O-linked N-acetylglucosamine transferase genes of Arabidopsis thaliana L. Heynh. Have overlapping functions necessary for gamete and seed development
-
Hartweck, L. M., Scott, C. L. and Olszewski, N. E. (2002) Two O-linked N-acetylglucosamine transferase genes of Arabidopsis thaliana L. Heynh. have overlapping functions necessary for gamete and seed development. Genetics 161, 1279-1291 (Pubitemid 34831451)
-
(2002)
Genetics
, vol.161
, Issue.3
, pp. 1279-1291
-
-
Hartweck, L.M.1
Scott, C.L.2
Olszewski, N.E.3
-
12
-
-
0024384636
-
Glycosylation in the nucleus and cytoplasm
-
Hart, G. W., Haltiwanger, R. S., Holt, G. D. and Kelly, W. G. (1989) Glycosylation in the nucleus and cytoplasm. Annu. Rev. Biochem. 58, 841-874 (Pubitemid 19172989)
-
(1989)
Annual Review of Biochemistry
, vol.58
, pp. 841-874
-
-
Hart, G.W.1
Haltiwanger, R.S.2
Holt, G.D.3
Kelly, W.G.4
-
13
-
-
77949286116
-
O-GlcNAc protein modification in plants: Evolution and function
-
Olszewski, N. E., West, C. M., Sassi, S. O. and Hartweck, L. M. (2010) O-GlcNAc protein modification in plants: evolution and function. Biochim. Biophys. Acta 1800, 49-56
-
(2010)
Biochim. Biophys. Acta
, vol.1800
, pp. 49-56
-
-
Olszewski, N.E.1
West, C.M.2
Sassi, S.O.3
Hartweck, L.M.4
-
14
-
-
33744543208
-
Comprehensive glycan analysis of recombinant Aspergillus niger endo-polygalacturonase C
-
DOI 10.1016/j.ab.2006.02.002, PII S0003269706000893
-
Woosley, B., Xie, M., Wells, L., Orlando, R., Garrison, D., King, D. and Bergmann, C. (2006) Comprehensive glycan analysis of recombinant Aspergillus niger endo-polygalacturonase C. Anal. Biochem. 354, 43-53 (Pubitemid 43816380)
-
(2006)
Analytical Biochemistry
, vol.354
, Issue.1
, pp. 43-53
-
-
Woosley, B.1
Xie, M.2
Wells, L.3
Orlando, R.4
Garrison, D.5
King, D.6
Bergmann, C.7
-
15
-
-
4644262462
-
O-GlcNAc transferase is in a functional complex with protein phosphatase 1 catalytic subunits
-
DOI 10.1074/jbc.M406481200
-
Wells, L., Kreppel, L. K., Comer, F. I., Wadzinski, B. E. and Hart, G. W. (2004) O-GlcNAc transferase is in a functional complex with protein phosphatase 1 catalytic subunits. J. Biol. Chem. 279, 38466-38470 (Pubitemid 39295998)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.37
, pp. 38466-38470
-
-
Wells, L.1
Kreppel, L.K.2
Comer, F.I.3
Wadzinski, B.E.4
Hart, G.W.5
-
16
-
-
69249155637
-
Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification
-
Dias, W. B., Cheung, W. D., Wang, Z. and Hart, G. W. (2009) Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification. J. Biol. Chem. 284, 21327-21337
-
(2009)
J. Biol. Chem
, vol.284
, pp. 21327-21337
-
-
Dias, W.B.1
Cheung, W.D.2
Wang, Z.3
Hart, G.W.4
-
17
-
-
0037032835
-
The protein kinase complement of the human genome
-
DOI 10.1126/science.1075762
-
Manning, G., Whyte, D. B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934 (Pubitemid 35425239)
-
(2002)
Science
, vol.298
, Issue.5600
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
18
-
-
0034630719
-
Structure of O-linked GlcNAc transferase: Mediator of glycan-dependent signaling
-
DOI 10.1006/bbrc.2000.2600
-
Roos, M. D. and Hanover, J. A. (2000) Structure of O-linked GlcNAc transferase: mediator of glycan-dependent signaling. Biochem. Biophys. Res. Commun. 271, 275-280 (Pubitemid 30444716)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.271
, Issue.2
, pp. 275-280
-
-
Roos, M.D.1
Hanover, J.A.2
-
19
-
-
0028085881
-
Purification and characterization of an O-GlcNAc selective N-acetyl-β-D-glucosaminidase from rat spleen cytosol
-
Dong, D. L. and Hart, G. W. (1994) Purification and characterization of an O-GlcNAc selective N-acetyl-β-D-glucosaminidase from rat spleen cytosol. J. Biol. Chem. 269, 19321-19330
-
(1994)
J. Biol. Chem
, vol.269
, pp. 19321-19330
-
-
Dong, D.L.1
Hart, G.W.2
-
20
-
-
50349093142
-
Cross-talk between GlcNAcylation and phosphorylation: Roles in insulin resistance and glucose toxicity
-
Copeland, R. J., Bullen, J. W. and Hart, G. W. (2008) Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity. Am. J. Physiol. Endocrinol. Metab. 295, E17-E28
-
(2008)
Am. J. Physiol. Endocrinol. Metab
, vol.295
-
-
Copeland, R.J.1
Bullen, J.W.2
Hart, G.W.3
-
21
-
-
84872263925
-
O-GlcNAc processing enzymes: Catalytic mechanisms, substrate specificity, and enzyme regulation
-
Vocadlo, D. J. (2012) O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation. Curr. Opin. Chem. Biol. 16, 488-497
-
(2012)
Curr. Opin. Chem. Biol
, vol.16
, pp. 488-497
-
-
Vocadlo, D.J.1
-
22
-
-
4744341309
-
The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin α
-
DOI 10.1038/nsmb833
-
Jínek, M., Rehwinkel, J., Lazarus, B. D., Izaurralde, E., Hanover, J. A. and Conti, E. (2004) The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha. Nat. Struct. Mol. Biol. 11, 1001-1007 (Pubitemid 39315305)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.10
, pp. 1001-1007
-
-
Jinek, M.1
Rehwinkel, J.2
Lazarus, B.D.3
Izaurralde, E.4
Hanover, J.A.5
Conti, E.6
-
23
-
-
77949309755
-
Structural analyses of enzymes involved in the O-GlcNAc modification
-
Martinez-Fleites, C., He, Y. and Davies, G. J. (2010) Structural analyses of enzymes involved in the O-GlcNAc modification. Biochim. Biophys. Acta 1800, 122-133
-
(2010)
Biochim. Biophys. Acta
, vol.1800
, pp. 122-133
-
-
Martinez-Fleites, C.1
He, Y.2
Davies, G.J.3
-
24
-
-
84857933257
-
Structural and functional discussion of the tetra-trico-peptide repeat, a protein interaction module
-
Zeytuni, N. and Zarivach, R. (2012) Structural and functional discussion of the tetra-trico-peptide repeat, a protein interaction module. Structure 20, 397-405
-
(2012)
Structure
, vol.20
, pp. 397-405
-
-
Zeytuni, N.1
Zarivach, R.2
-
25
-
-
84872953223
-
TET2 promotes histone O-GlcNAcylation during gene transcription
-
Chen, Q., Chen, Y., Bian, C., Fujiki, R. and Yu, X. (2013) TET2 promotes histone O-GlcNAcylation during gene transcription. Nature 493, 561-564
-
(2013)
Nature
, vol.493
, pp. 561-564
-
-
Chen, Q.1
Chen, Y.2
Bian, C.3
Fujiki, R.4
Yu, X.5
-
26
-
-
84874266225
-
Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells
-
Vella, P., Scelfo, A., Jammula, S., Chiacchiera, F., Williams, K., Cuomo, A., Roberto, A., Christensen, J., Bonaldi, T., Helin, K. et al. (2013) Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells. Mol. Cell 49, 645-656
-
(2013)
Mol. Cell
, vol.49
, pp. 645-656
-
-
Vella, P.1
Scelfo, A.2
Jammula, S.3
Chiacchiera, F.4
Williams, K.5
Cuomo, A.6
Roberto, A.7
Christensen, J.8
Bonaldi, T.9
Helin, K.10
-
27
-
-
57749088688
-
O-linked β-N-acetylglucosaminyltransferase substrate specificity is regulated by myosin phosphatase targeting and other interacting proteins
-
Cheung, W. D., Sakabe, K., Housley, M. P., Dias, W. B. and Hart, G. W. (2008) O-linked β-N-acetylglucosaminyltransferase substrate specificity is regulated by myosin phosphatase targeting and other interacting proteins. J. Biol. Chem. 283, 33935-33941
-
(2008)
J. Biol. Chem
, vol.283
, pp. 33935-33941
-
-
Cheung, W.D.1
Sakabe, K.2
Housley, M.P.3
Dias, W.B.4
Hart, G.W.5
-
28
-
-
0037067659
-
Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: Coupling protein O-GlcNAcylation to transcriptional repression
-
DOI 10.1016/S0092-8674(02)00810-3
-
Yang, X., Zhang, F. and Kudlow, J. E. (2002) Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression. Cell 110, 69-80 (Pubitemid 34874607)
-
(2002)
Cell
, vol.110
, Issue.1
, pp. 69-80
-
-
Yang, X.1
Zhang, F.2
Kudlow, J.E.3
-
29
-
-
0034705030
-
The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny
-
DOI 10.1073/pnas.100471497
-
Shafi, R., Iyer, S. P. N., Ellies, L. G., O'Donnell, N., Marek, K. W., Chui, D., Hart, G. W. and Marth, J. D. (2000) The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny. Proc. Natl. Acad. Sci. U. S. A. 97, 5735-5739 (Pubitemid 30367467)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.11
, pp. 5735-5739
-
-
Shafi, R.1
Iyer, S.P.N.2
Ellies, L.G.3
O'Donnell, N.4
Marek, K.W.5
Chui, D.6
Hart, G.W.7
Marth, J.D.8
-
30
-
-
84863622379
-
O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network
-
Jang, H., Kim, T. W., Yoon, S., Choi, S.-Y., Kang, T.-W., Kim, S.-Y., Kwon, Y.-W., Cho, E.-J. and Youn, H.-D. (2012) O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network. Cell Stem Cell 11, 62-74
-
(2012)
Cell Stem Cell
, vol.11
, pp. 62-74
-
-
Jang, H.1
Kim, T.W.2
Yoon, S.3
Choi, S.-Y.4
Kang, T.-W.5
Kim, S.-Y.6
Kwon, Y.-W.7
Cho, E.-J.8
Youn, H.-D.9
-
31
-
-
25444501339
-
Perturbations in O-linked β-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis
-
DOI 10.1074/jbc.M503396200
-
Slawson, C., Zachara, N. E., Vosseller, K., Cheung, W. D., Lane, M. D. and Hart, G. W. (2005) Perturbations in O-linked β-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis. J. Biol. Chem. 280, 32944-32956 (Pubitemid 41368344)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.38
, pp. 32944-32956
-
-
Slawson, C.1
Zachara, N.E.2
Vosseller, K.3
Cheung, W.D.4
Lane, M.D.5
Hart, G.W.6
-
32
-
-
77949305110
-
Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase
-
Macauley, M. S. and Vocadlo, D. J. (2010) Increasing O-GlcNAc levels: an overview of small-molecule inhibitors of O-GlcNAcase. Biochim. Biophys. Acta 1800, 107-121
-
(2010)
Biochim. Biophys. Acta
, vol.1800
, pp. 107-121
-
-
Macauley, M.S.1
Vocadlo, D.J.2
-
33
-
-
84864254567
-
Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology
-
Gloster, T. M. and Vocadlo, D. J. (2012) Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology. Nat. Chem. Biol. 8, 683-694
-
(2012)
Nat. Chem. Biol
, vol.8
, pp. 683-694
-
-
Gloster, T.M.1
Vocadlo, D.J.2
-
34
-
-
79954429001
-
Substrate and product analogues as human O-GlcNAc transferase inhibitors
-
Dorfmueller, H. C., Borodkin, V. S., Blair, D. E., Pathak, S., Navratilova, I. and van Aalten, D. M. F. (2011) Substrate and product analogues as human O-GlcNAc transferase inhibitors. Amino Acids 40, 781-792
-
(2011)
Amino Acids
, vol.40
, pp. 781-792
-
-
Dorfmueller, H.C.1
Borodkin, V.S.2
Blair, D.E.3
Pathak, S.4
Navratilova, I.5
Van Aalten, D.M.F.6
-
35
-
-
84887135413
-
Tools for probing and perturbing O-GlcNAc in cells and in vivo
-
doi:10.1016/j.cbpa.2013.06.030
-
Cecioni, S. and Vocadlo, D. J. (2013) Tools for probing and perturbing O-GlcNAc in cells and in vivo. Curr. Opin. Chem. Biol., doi:10.1016/j.cbpa.2013. 06.030
-
(2013)
Curr. Opin. Chem. Biol.
-
-
Cecioni, S.1
Vocadlo, D.J.2
-
36
-
-
58149200943
-
The Carbohydrate-Active EnZymes database (CAZy): An expert resource for glycogenomics
-
Cantarel, B. L., Coutinho, P. M., Rancurel, C., Bernard, T., Lombard, V. and Henrissat, B. (2009) The Carbohydrate-Active EnZymes database (CAZy): an expert resource for glycogenomics. Nucleic Acids Res. 37, D233-D238
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Cantarel, B.L.1
Coutinho, P.M.2
Rancurel, C.3
Bernard, T.4
Lombard, V.5
Henrissat, B.6
-
37
-
-
0030959555
-
Dynamic glycosylation of nuclear and cytosolic proteins: Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats
-
DOI 10.1074/jbc.272.14.9308
-
Kreppel, L. K., Blomberg, M. A. and Hart, G. W. (1997) Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats. J. Biol. Chem. 272, 9308-9315 (Pubitemid 27154943)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.14
, pp. 9308-9315
-
-
Kreppel, L.K.1
Blomberg, M.A.2
Hart, G.W.3
-
38
-
-
54349112556
-
Structural insights into mechanism and specificity of O-GlcNAc transferase
-
Clarke, A. J., Hurtado-Guerrero, R., Pathak, S., Schüttelkopf, A. W., Borodkin, V., Shepherd, S. M., Ibrahim, A. F. M. and van Aalten, D. M. F. (2008) Structural insights into mechanism and specificity of O-GlcNAc transferase. EMBO J. 27, 2780-2788
-
(2008)
EMBO J
, vol.27
, pp. 2780-2788
-
-
Clarke, A.J.1
Hurtado-Guerrero, R.2
Pathak, S.3
Schüttelkopf, A.W.4
Borodkin, V.5
Shepherd, S.M.6
Ibrahim, A.F.M.7
Van Aalten, D.M.F.8
-
39
-
-
46449085222
-
Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation
-
DOI 10.1038/nsmb.1443, PII NSMB1443
-
Martinez-Fleites, C., Macauley, M. S., He, Y., Shen, D. L., Vocadlo, D. J. and Davies, G. J. (2008) Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation. Nat. Struct. Mol. Biol. 15, 764-765 (Pubitemid 351932003)
-
(2008)
Nature Structural and Molecular Biology
, vol.15
, Issue.7
, pp. 764-765
-
-
Martinez-Fleites, C.1
Macauley, M.S.2
He, Y.3
Shen, D.L.4
Vocadlo, D.J.5
Davies, G.J.6
-
40
-
-
79251611901
-
Structure of human O-GlcNAc transferase and its complex with a peptide substrate
-
Lazarus, M. B., Nam, Y., Jiang, J., Sliz, P. and Walker, S. (2011) Structure of human O-GlcNAc transferase and its complex with a peptide substrate. Nature 469, 564-567
-
(2011)
Nature
, vol.469
, pp. 564-567
-
-
Lazarus, M.B.1
Nam, Y.2
Jiang, J.3
Sliz, P.4
Walker, S.5
-
41
-
-
84870384002
-
O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis
-
Schimpl, M., Zheng, X., Borodkin, V. S., Blair, D. E., Ferenbach, A. T., Schüttelkopf, A. W., Navratilova, I., Aristotelous, T., Albarbarawi, O., Robinson, D. A et al. (2012) O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis. Nat. Chem. Biol. 8, 969-974
-
(2012)
Nat. Chem. Biol
, vol.8
, pp. 969-974
-
-
Schimpl, M.1
Zheng, X.2
Borodkin, V.S.3
Blair, D.E.4
Ferenbach, A.T.5
Schüttelkopf, A.W.6
Navratilova, I.7
Aristotelous, T.8
Albarbarawi, O.9
Robinson, D.A.10
-
42
-
-
0036290413
-
Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase
-
DOI 10.1016/S0006-291X(02)00200-0, PII S0006291X02002000
-
Konrad, R. J., Zhang, F., Hale, J. E., Knierman, M. D., Becker, G. W. and Kudlow, J. E. (2002) Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase. Biochem. Biophys. Res. Commun. 293, 207-212 (Pubitemid 34694192)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.293
, Issue.1
, pp. 207-212
-
-
Konrad, R.J.1
Zhang, F.2
Hale, J.E.3
Knierman, M.D.4
Becker, G.W.5
Kudlow, J.E.6
-
43
-
-
0023793347
-
Inhibition of glucokinase by alloxan through interaction with SH groups in the sugar-binding site of the enzyme
-
Lenzen, S., Freytag, S. and Panten, U. (1988) Inhibition of glucokinase by alloxan through interaction with SH groups in the sugar-binding site of the enzyme. Mol. Pharmacol. 34, 395-400
-
(1988)
Mol. Pharmacol
, vol.34
, pp. 395-400
-
-
Lenzen, S.1
Freytag, S.2
Panten, U.3
-
44
-
-
0018192154
-
Alloxan uptake by isolated rat islets of langerhans
-
Weaver, D. C., McDaniel, M. L. and Lacy, P. E. (1978) Alloxan uptake by isolated rat islets of Langerhans. Endocrinology 102, 1847-1855 (Pubitemid 8376446)
-
(1978)
Endocrinology
, vol.102
, Issue.6
, pp. 1847-1855
-
-
Weaver, D.C.1
McDaniel, M.L.2
Lacy, P.E.3
-
45
-
-
0020467282
-
Selective uptake of alloxan by pancreatic B-cells
-
Gorus, F. K., Malaisse, W. J. and Pipeleers, D. G. (1982) Selective uptake of alloxan by pancreatic β-cells. Biochem. J. 208, 513-515 (Pubitemid 13166396)
-
(1982)
Biochemical Journal
, vol.208
, Issue.2
, pp. 513-515
-
-
Gorus, F.K.1
Malaisse, W.J.2
Pipeleers, D.G.3
-
46
-
-
37549029242
-
The mechanisms of alloxan-and streptozotocin-induced diabetes
-
Lenzen, S. (2008) The mechanisms of alloxan-and streptozotocin-induced diabetes. Diabetologia 51, 216-226
-
(2008)
Diabetologia
, vol.51
, pp. 216-226
-
-
Lenzen, S.1
-
47
-
-
65749113176
-
Cardioprotection of salidroside from ischemia/reperfusion injury by increasing N-acetylglucosamine linkage to cellular proteins
-
Wu, T., Zhou, H., Jin, Z., Bi, S., Yang, X., Yi, D. and Liu, W. (2009) Cardioprotection of salidroside from ischemia/reperfusion injury by increasing N-acetylglucosamine linkage to cellular proteins. Eur. J. Pharmacol. 613, 93-99
-
(2009)
Eur. J. Pharmacol
, vol.613
, pp. 93-99
-
-
Wu, T.1
Zhou, H.2
Jin, Z.3
Bi, S.4
Yang, X.5
Yi, D.6
Liu, W.7
-
49
-
-
71249160061
-
O-linked β-N-acetylglucosaminylation in mouse embryonic neural precursor cells
-
Yanagisawa, M. and Yu, R. K. (2009) O-linked β-N- acetylglucosaminylation in mouse embryonic neural precursor cells. J. Neurosci. Res. 87, 3535-3545
-
(2009)
J. Neurosci. Res
, vol.87
, pp. 3535-3545
-
-
Yanagisawa, M.1
Yu, R.K.2
-
50
-
-
84873351364
-
Glucose sensor O-GlcNAcylation coordinates with phosphorylation to regulate circadian clock
-
Kaasik, K., Kivimäe, S., Allen, J. J., Chalkley, R. J., Huang, Y., Baer, K., Kissel, H., Burlingame, A. L., Shokat, K. M., Ptáček, L. J. et al. (2013) Glucose sensor O-GlcNAcylation coordinates with phosphorylation to regulate circadian clock. Cell Metab. 17, 291-302
-
(2013)
Cell Metab
, vol.17
, pp. 291-302
-
-
Kaasik, K.1
Kivimäe, S.2
Allen, J.J.3
Chalkley, R.J.4
Huang, Y.5
Baer, K.6
Kissel, H.7
Burlingame, A.L.8
Shokat, K.M.9
Ptáček, L.J.10
-
51
-
-
34250373346
-
2/M transition in Xenopus laevis oocytes
-
DOI 10.1074/jbc.M700444200
-
2/M transition in Xenopus laevis oocytes. J. Biol. Chem. 282, 12527-12536 (Pubitemid 47100627)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.17
, pp. 12527-12536
-
-
Dehennaut, V.1
Lefebvre, T.2
Sellier, C.3
Leroy, Y.4
Gross, B.5
Walker, S.6
Cacan, R.7
Michalski, J.-C.8
Vilain, J.-P.9
Bodart, J.-F.10
-
52
-
-
58649120835
-
In vivomodulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation
-
Tallent, M. K., Varghis, N., Skorobogatko, Y., Hernandez-Cuebas, L., Whelan, K., Vocadlo, D. J. and Vosseller, K. (2009) In vivomodulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. J. Biol. Chem. 284, 174-181
-
(2009)
J. Biol. Chem
, vol.284
, pp. 174-181
-
-
Tallent, M.K.1
Varghis, N.2
Skorobogatko, Y.3
Hernandez-Cuebas, L.4
Whelan, K.5
Vocadlo, D.J.6
Vosseller, K.7
-
53
-
-
0034653920
-
Importance of cysteine residues for the stability and catalytic activity of human pancreatic beta cell glucokinase
-
DOI 10.1006/abbi.1999.1666
-
Tiedge, M., Richter, T. and Lenzen, S. (2000) Importance of cysteine residues for the stability and catalytic activity of human pancreatic β cell glucokinase. Arch. Biochem. Biophys. 375, 251-260 (Pubitemid 30158381)
-
(2000)
Archives of Biochemistry and Biophysics
, vol.375
, Issue.2
, pp. 251-260
-
-
Tiedge, M.1
Richter, T.2
Lenzen, S.3
-
54
-
-
33750090697
-
Alloxan is an inhibitor of O-GlcNAc-selective N-acetyl-β-D- glucosaminidase
-
Lee, T. N., Alborn, W. E., Knierman, M. D. and Konrad, R. J. (2006) Alloxan is an inhibitor of O-GlcNAc-selective N-acetyl-β-D-glucosaminidase. Biochem. Biophys. Res. Commun. 350, 1038-1043
-
(2006)
Biochem. Biophys. Res. Commun
, vol.350
, pp. 1038-1043
-
-
Lee, T.N.1
Alborn, W.E.2
Knierman, M.D.3
Konrad, R.J.4
-
55
-
-
0025823868
-
Thiol-group reactivity, hydrophilicity and stability of alloxan, its reduction products and its N-methyl derivatives and a comparison with ninhydrin
-
Lenzen, S. and Munday, R. (1991) Thiol-group reactivity, hydrophilicity and stability of alloxan, its reduction products and its N-methyl derivatives and a comparison with ninhydrin. Biochem. Pharmacol. 42, 1385-1391
-
(1991)
Biochem. Pharmacol
, vol.42
, pp. 1385-1391
-
-
Lenzen, S.1
Munday, R.2
-
56
-
-
72449192809
-
Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation
-
Cohen, P. (2010) Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation. Biochem. J. 425, 53-54
-
(2010)
Biochem. J
, vol.425
, pp. 53-54
-
-
Cohen, P.1
-
57
-
-
27144455345
-
Discovery of O-GlcNAc transferase inhibitors
-
DOI 10.1021/ja0555217
-
Gross, B. J., Kraybill, B. C. and Walker, S. (2005) Discovery of O-GlcNAc transferase inhibitors. J. Am. Chem. Soc. 127, 14588-14589 (Pubitemid 41510995)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.42
, pp. 14588-14589
-
-
Gross, B.J.1
Kraybill, B.C.2
Walker, S.3
-
58
-
-
33644874204
-
The hexosamine signaling pathway: Deciphering the 'O-GlcNAc code'
-
Love, D. C. and Hanover, J. A. (2005) The hexosamine signaling pathway: deciphering the 'O-GlcNAc code'. Sci. STKE 2005, re13
-
(2005)
Sci. STKE
, vol.2005
-
-
Love, D.C.1
Hanover, J.A.2
-
59
-
-
84879063538
-
Epigenetic switching by the metabolism-sensing factors in the generation of orexin neurons from mouse embryonic stem cells
-
Hayakawa, K., Hirosawa, M., Tabei, Y., Arai, D., Tanaka, S., Murakami, N., Yagi, S. and Shiota, K. (2013) Epigenetic switching by the metabolism-sensing factors in the generation of orexin neurons from mouse embryonic stem cells. J. Biol. Chem. 288, 17099-17110
-
(2013)
J. Biol. Chem
, vol.288
, pp. 17099-17110
-
-
Hayakawa, K.1
Hirosawa, M.2
Tabei, Y.3
Arai, D.4
Tanaka, S.5
Murakami, N.6
Yagi, S.7
Shiota, K.8
-
60
-
-
77953864480
-
Toxic effects of hyperglycemia are mediated by the hexosamine signaling pathway and O-linked glycosylation in early mouse embryos
-
Pantaleon, M., Tan, H. Y., Kafer, G. R. and Kaye, P. L. (2010) Toxic effects of hyperglycemia are mediated by the hexosamine signaling pathway and O-linked glycosylation in early mouse embryos. Biol. Reprod. 82, 751-758
-
(2010)
Biol. Reprod
, vol.82
, pp. 751-758
-
-
Pantaleon, M.1
Tan, H.Y.2
Kafer, G.R.3
Kaye, P.L.4
-
61
-
-
45149112314
-
O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic β cells
-
DOI 10.1016/j.yexcr.2008.04.014, PII S0014482708001791
-
473 correlates with apoptosis of murine pancreatic β cells. Exp. Cell Res. 314, 2238-2248 (Pubitemid 351833109)
-
(2008)
Experimental Cell Research
, vol.314
, Issue.11-12
, pp. 2238-2248
-
-
Kang, E.-S.1
Han, D.2
Park, J.3
Kwak, T.K.4
Oh, M.-A.5
Lee, S.-A.6
Choi, S.7
Park, Z.Y.8
Kim, Y.9
Lee, J.W.10
-
62
-
-
6944246692
-
Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic β-cells
-
DOI 10.1096/fj.03-0725fje
-
D'Alessandris, C., Andreozzi, F., Federici, M., Cardellini, M., Brunetti, A., Ranalli, M., Del Guerra, S., Lauro, D., Del Prato, S., Marchetti, P. et al. (2004) Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic β-cells. FASEB J. 18, 959-961 (Pubitemid 39561491)
-
(2004)
FASEB Journal
, vol.18
, Issue.9
, pp. 959-961
-
-
D'Alessandris, C.1
Andreozzi, F.2
Federici, M.3
Cardellini, M.4
Brunetti, A.5
Ranalli, M.6
Del Guerra, S.7
Lauro, D.8
Del Prato, S.9
Marchetti, P.10
Lauro, R.11
Sesti, G.12
-
63
-
-
3042534011
-
Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress: A survival response of mammalian cells
-
DOI 10.1074/jbc.M403773200
-
Zachara, N. E., O'Donnell, N., Cheung, W. D., Mercer, J. J., Marth, J. D. and Hart, G. W. (2004) Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J. Biol. Chem. 279, 30133-30142 (Pubitemid 38937936)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.29
, pp. 30133-30142
-
-
Zachara, N.E.1
O'Donnell, N.2
Cheung, W.D.3
Mercer, J.J.4
Marth, J.D.5
Hart, G.W.6
-
64
-
-
0034663705
-
Responsiveness of the state of O-linked N-acetylglucosamine modification of nuclear pore protein p62 to the extracellular glucose concentration
-
Han, I., Oh, E. S. and Kudlow, J. E. (2000) Responsiveness of the state of O-linked N-acetylglucosamine modification of nuclear pore protein p62 to the extracellular glucose concentration. Biochem. J. 350, 109-114
-
(2000)
Biochem. J
, vol.350
, pp. 109-114
-
-
Han, I.1
Oh, E.S.2
Kudlow, J.E.3
-
65
-
-
47749149232
-
O-GlcNAc regulates FoxO activation in response to glucose
-
Housley, M. P., Rodgers, J. T., Udeshi, N. D., Kelly, T. J., Shabanowitz, J., Hunt, D. F., Puigserver, P. and Hart, G. W. (2008) O-GlcNAc regulates FoxO activation in response to glucose. J. Biol. Chem. 283, 16283-16292
-
(2008)
J. Biol. Chem
, vol.283
, pp. 16283-16292
-
-
Housley, M.P.1
Rodgers, J.T.2
Udeshi, N.D.3
Kelly, T.J.4
Shabanowitz, J.5
Hunt, D.F.6
Puigserver, P.7
Hart, G.W.8
-
66
-
-
0042467933
-
6-Diazo-5-oxo-L-norleucine, a new tumor-inhibitory substance. II. Isolation and characterization
-
Dion, H. W., Fusari, S. A., Jakubowski, Z. L., Zora, J. G. and Bartz, Q. R. (1956) 6-Diazo-5-oxo-L-norleucine, a new tumor-inhibitory substance. II. Isolation and characterization. J. Am. Chem. Soc. 78, 3075
-
(1956)
J. Am. Chem. Soc
, vol.78
, pp. 3075
-
-
Dion, H.W.1
Fusari, S.A.2
Jakubowski, Z.L.3
Zora, J.G.4
Bartz, Q.R.5
-
67
-
-
0036231781
-
Flux through the hexosamine pathway is a determinant of nuclear factor kappaB-dependent promoter activation
-
James, L. R., Tang, D., Ingram, A., Ly, H., Thai, K., Cai, L. and Scholey, J. W. (2002) Flux through the hexosamine pathway is a determinant of nuclear factor κB-dependent promoter activation. Diabetes 51, 1146-1156 (Pubitemid 34438362)
-
(2002)
Diabetes
, vol.51
, Issue.4
, pp. 1146-1156
-
-
James, L.R.1
Tang, D.2
Ingram, A.3
Ly, H.4
Thai, K.5
Cai, L.6
Seholey, J.W.7
-
68
-
-
0034809649
-
Angiotensin II activates the GFAT promoter in mesangial cells
-
James, L. R., Ingram, A., Ly, H., Thai, K., Cai, L. and Scholey, J. W. (2001) Angiotensin II activates the GFAT promoter in mesangial cells. Am. J. Physiol. Renal Physiol. 281, F151-F162
-
(2001)
Am. J. Physiol. Renal Physiol
, vol.281
-
-
James, L.R.1
Ingram, A.2
Ly, H.3
Thai, K.4
Cai, L.5
Scholey, J.W.6
-
69
-
-
19244367255
-
Permanent exposure of mucin-secreting HT-29 cells to benzyl-N-acetyl- α-D-galactosaminide induces abnormal O-glycosylation of mucins and inhibits constitutive and stimulated MUC5AC secretion
-
Hennebicq-Reig, S., Lesuffleur, T., Capon, C., De Bolos, C., Kim, I., Moreau, O., Richet, C., Hemon, B., Recchi, M. A., Maes, E. et al. (1998) Permanent exposure of mucin-secreting HT-29 cells to benzyl-N-acetyl-α-D- galactosaminide induces abnormal O-glycosylation of mucins and inhibits constitutive and stimulated MUC5AC secretion. Biochem. J. 334, 283-295 (Pubitemid 28421000)
-
(1998)
Biochemical Journal
, vol.334
, Issue.1
, pp. 283-295
-
-
Hennebicq-Reig, S.1
Lesuffleur, T.2
Capon, C.3
De Bolos, C.4
Kim, I.5
Moreau, O.6
Richet, C.7
Hemon, B.8
Recchi, M.-A.9
Maes, E.10
Aubert, J.-P.11
Real, F.X.12
Zweibaum, A.13
Delannoy, P.14
Degand, P.15
Huet, G.16
-
70
-
-
0034646330
-
Glucose stimulates protein modification by O-linked GlcNAc in pancreatic cells: Linkage of O-linked GlcNAc to β cell death
-
DOI 10.1073/pnas.97.6.2820
-
Liu, K., Paterson, A. J., Chin, E. and Kudlow, J. E. (2000) Glucose stimulates protein modification by O-linked GlcNAc in pancreatic β cells: linkage of O-linked GlcNAc to β cell death. Proc. Natl. Acad. Sci. U. S. A. 97, 2820-2825 (Pubitemid 30159255)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.6
, pp. 2820-2825
-
-
Liu, K.1
Paterson, A.J.2
Chin, E.3
Kudlow, J.E.4
-
71
-
-
83655163673
-
A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase
-
Jiang, J., Lazarus, M. B., Pasquina, L., Sliz, P. and Walker, S. (2012) A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase. Nat. Chem. Biol. 8, 72-77
-
(2012)
Nat. Chem. Biol
, vol.8
, pp. 72-77
-
-
Jiang, J.1
Lazarus, M.B.2
Pasquina, L.3
Sliz, P.4
Walker, S.5
-
72
-
-
84882607514
-
O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer
-
Itkonen, H. M., Minner, S., Guldvik, I. J., Sandmann, M. J., Tsourlakis, M. C., Berge, V., Svindland, A., Schlomm, T. and Mills, I. G. (2013) O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer. Cancer Res. 73, 5277-5287
-
(2013)
Cancer Res
, vol.73
, pp. 5277-5287
-
-
Itkonen, H.M.1
Minner, S.2
Guldvik, I.J.3
Sandmann, M.J.4
Tsourlakis, M.C.5
Berge, V.6
Svindland, A.7
Schlomm, T.8
Mills, I.G.9
-
73
-
-
69949132009
-
The hexosamine biosynthesis pathway is essential for pancreatic beta cell development
-
Filhoulaud, G., Guillemain, G. and Scharfmann, R. (2009) The hexosamine biosynthesis pathway is essential for pancreatic beta cell development. J. Biol. Chem. 284, 24583-24594
-
(2009)
J. Biol. Chem
, vol.284
, pp. 24583-24594
-
-
Filhoulaud, G.1
Guillemain, G.2
Scharfmann, R.3
-
74
-
-
79951855712
-
Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells
-
Gloster, T. M., Zandberg, W. F., Heinonen, J. E., Shen, D. L., Deng, L. and Vocadlo, D. J. (2011) Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells. Nat. Chem. Biol. 7, 174-181
-
(2011)
Nat. Chem. Biol
, vol.7
, pp. 174-181
-
-
Gloster, T.M.1
Zandberg, W.F.2
Heinonen, J.E.3
Shen, D.L.4
Deng, L.5
Vocadlo, D.J.6
-
75
-
-
84871950193
-
Serum-stimulated cell cycle entry promotes ncOGT synthesis required for cyclin D expression
-
Olivier-Van Stichelen, S., Drougat, L., Dehennaut, V., El Yazidi-Belkoura, I., Guinez, C., Mir, A.-M., Michalski, J.-C., Vercoutter-Edouart, A.-S. and Lefebvre, T. (2012) Serum-stimulated cell cycle entry promotes ncOGT synthesis required for cyclin D expression. Oncogenesis 1, e36
-
(2012)
Oncogenesis
, vol.1
-
-
Olivier-Van Stichelen, S.1
Drougat, L.2
Dehennaut, V.3
El Yazidi-Belkoura, I.4
Guinez, C.5
Mir, A.-M.6
Michalski, J.-C.7
Vercoutter-Edouart, A.-S.8
Lefebvre, T.9
-
76
-
-
84883416868
-
Insulin signaling controls the expression of O-GlcNAc transferase and its interaction with lipid microdomains
-
Perez-Cervera, Y., Dehennaut, V., Aquino Gil, M., Guedri, K., Solorzano Mata, C. J., Olivier-Van Stichelen, S., Michalski, J.-C., Foulquier, F. and Lefebvre, T. (2013) Insulin signaling controls the expression of O-GlcNAc transferase and its interaction with lipid microdomains. FASEB J. 27, 3478-3486
-
(2013)
FASEB J
, vol.27
, pp. 3478-3486
-
-
Perez-Cervera, Y.1
Dehennaut, V.2
Aquino Gil, M.3
Guedri, K.4
Solorzano Mata, C.J.5
Olivier-Van Stichelen, S.6
Michalski, J.-C.7
Foulquier, F.8
Lefebvre, T.9
-
77
-
-
84878225772
-
Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells
-
Ma, Z., Vocadlo, D. J. and Vosseller, K. (2013) Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells. J. Biol. Chem. 288, 15121-15130
-
(2013)
J. Biol. Chem
, vol.288
, pp. 15121-15130
-
-
Ma, Z.1
Vocadlo, D.J.2
Vosseller, K.3
-
78
-
-
34247583996
-
Cycling of O-linked β-N-acetylglucosamine on nucleocytoplasmic proteins
-
DOI 10.1038/nature05815, PII NATURE05815
-
Hart, G. W., Housley M. P. and Slawson, C. (2007) Cycling of O-linked β-N-acetylglucosamine on nucleocytoplasmic proteins. Nature 446, 1017-1022 (Pubitemid 46676063)
-
(2007)
Nature
, vol.446
, Issue.7139
, pp. 1017-1022
-
-
Hart, G.W.1
Housley, M.P.2
Slawson, C.3
-
79
-
-
21844464281
-
O-GlcNAcase uses substrate-assisted catalysis: Kinetic analysis and development of highly selective mechanism-inspired inhibitors
-
DOI 10.1074/jbc.M413819200
-
Macauley, M. S., Whitworth, G. E., Debowski, A. W., Chin, D. and Vocadlo, D. J. (2005) O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors. J. Biol. Chem. 280, 25313-25322 (Pubitemid 40962233)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.27
, pp. 25313-25322
-
-
Macauley, M.S.1
Whitworth, G.E.2
Debowski, A.W.3
Chin, D.4
Vocadlo, D.J.5
-
80
-
-
33645735070
-
Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis
-
Rao, F. V., Dorfmueller, H. C., Villa, F., Allwood, M., Eggleston, I. M. and van Aalten, D. M. F (2006) Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis. EMBO J. 25, 1569-1578
-
(2006)
EMBO J
, vol.25
, pp. 1569-1578
-
-
Rao, F.V.1
Dorfmueller, H.C.2
Villa, F.3
Allwood, M.4
Eggleston, I.M.5
Van Aalten, D.M.F.6
-
81
-
-
0031719031
-
Streptozotocin, an analog of N-acetylglucosamine, blocks the removal of O-GlcNAc from intracellular proteins
-
Roos, M. D., Xie, W., Su, K., Clark, J. A., Yang, X., Chin, E., Paterson, A. J. and Kudlow, J. E. (1998) Streptozotocin, an analog of N-acetylglucosamine, blocks the removal of O-GlcNAc from intracellular proteins. Proc. Assoc. Am. Physicians 110, 422-432 (Pubitemid 28421930)
-
(1998)
Proceedings of the Association of American Physicians
, vol.110
, Issue.5
, pp. 422-432
-
-
Roos, M.D.1
Xie, W.2
Su, K.3
Clark, J.A.4
Yang, X.5
Chin, E.6
Paterson, A.J.7
Kudlow, J.E.8
-
82
-
-
0034614349
-
Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets
-
DOI 10.1006/bbrc.1999.1895
-
Konrad, R. J., Janowski, K. M. and Kudlow, J. E. (2000) Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets. Biochem. Biophys. Res. Commun. 267, 26-32 (Pubitemid 30072502)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.267
, Issue.1
, pp. 26-32
-
-
Konrad, R.J.1
Janowski, K.M.2
Kudlow, J.E.3
-
83
-
-
78649383623
-
Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases
-
Dorfmueller, H. C., Borodkin, V. S., Schimpl, M., Zheng, X., Kime, R., Read, K. D. and van Aalten, D. M. F. (2010) Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases. Chem. Biol. 17, 1250-1255
-
(2010)
Chem. Biol
, vol.17
, pp. 1250-1255
-
-
Dorfmueller, H.C.1
Borodkin, V.S.2
Schimpl, M.3
Zheng, X.4
Kime, R.5
Read, K.D.6
Van Aalten, D.M.F.7
-
84
-
-
49449101898
-
Chemical dissection of the link between streptozotocin, O-GlcNAc, and pancreatic cell death
-
Pathak, S., Dorfmueller, H. C., Borodkin, V. S. and van Aalten, D. M. F. (2008) Chemical dissection of the link between streptozotocin, O-GlcNAc, and pancreatic cell death. Chem. Biol. 15, 799-807
-
(2008)
Chem. Biol
, vol.15
, pp. 799-807
-
-
Pathak, S.1
Dorfmueller, H.C.2
Borodkin, V.S.3
Van Aalten, D.M.F.4
-
85
-
-
73649197648
-
Studies on the diabetogenic action of streptozotocin (NSC-37917)
-
Raikieten, N., Raikieten, M. L. and Nadkarni, M. V. (1963) Studies on the diabetogenic action of streptozotocin (NSC-37917). Cancer Chemother. Rep. 29, 91-98
-
(1963)
Cancer Chemother. Rep
, vol.29
, pp. 91-98
-
-
Raikieten, N.1
Raikieten, M.L.2
Nadkarni, M.V.3
-
86
-
-
0033080192
-
Elevated O-linked N-acetylglucosamine metabolism in pancreatic β-cells
-
DOI 10.1006/abbi.1998.1016
-
Hanover, J. A., Lai, Z., Lee, G., Lubas, W. A. and Sato, S. M. (1999) Elevated O-linked N-acetylglucosamine metabolism in pancreatic β-cells. Arch. Biochem. Biophys. 362, 38-45 (Pubitemid 29391649)
-
(1999)
Archives of Biochemistry and Biophysics
, vol.362
, Issue.1
, pp. 38-45
-
-
Hanover, J.A.1
Lai, Z.2
Lee, G.3
Lubas, W.A.4
Sato, S.M.5
-
87
-
-
0028604486
-
STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells
-
Schnedl, W. J., Ferber, S., Johnson, J. H. and Newgard, C. B. (1994) STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells. Diabetes 43, 1326-1333
-
(1994)
Diabetes
, vol.43
, pp. 1326-1333
-
-
Schnedl, W.J.1
Ferber, S.2
Johnson, J.H.3
Newgard, C.B.4
-
88
-
-
0035872219
-
The potential mechanism of the diabetooenic action of streptozotocin: Inhibition of pancreatic β-cell O-GlcNAc-selective N-acetyl-β-D- glucosaminidase
-
DOI 10.1042/0264-6021:3560031
-
Konrad, R. J., Mikolaenko, I., Tolar, J. F., Liu, K. and Kudlow, J. E. (2001) The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic β-cell O-GlcNAc-selective N-acetyl-β-D- glucosaminidase. Biochem. J. 356, 31-41 (Pubitemid 34275703)
-
(2001)
Biochemical Journal
, vol.356
, Issue.1
, pp. 31-41
-
-
Konrad, R.J.1
Mikolaenko, I.2
Tolar, J.F.3
Liu, K.4
Kudlow, J.E.5
-
89
-
-
29644436424
-
Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog
-
DOI 10.1016/j.bbrc.2005.12.041, PII S0006291X05027907
-
Toleman, C., Paterson, A. J., Shin, R. and Kudlow, J. E. (2006) Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog. Biochem. Biophys. Res. Commun. 340, 526-534 (Pubitemid 43021780)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.340
, Issue.2
, pp. 526-534
-
-
Toleman, C.1
Paterson, A.J.2
Shin, R.3
Kudlow, J.E.4
-
90
-
-
0034669371
-
Streptozotocin-induced β-cell death is independent of its inhibition of O-GlcNAcase in pancreatic Min6 cells
-
Gao, Y., Parker, G. J. and Hart, G. W. (2000) Streptozotocin-induced β-cell death is independent of its inhibition of O-GlcNAcase in pancreatic Min6 cells. Arch. Biochem. Biophys. 383, 296-302
-
(2000)
Arch. Biochem. Biophys
, vol.383
, pp. 296-302
-
-
Gao, Y.1
Parker, G.J.2
Hart, G.W.3
-
91
-
-
0019812690
-
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets
-
Yamamoto, H., Uchigata, Y. and Okamoto, H. (1981) Streptozotocin and alloxan induce DNA strand breaks and poly (ADP-ribose) synthetase in pancreatic islets. Nature 294, 284-286 (Pubitemid 12221500)
-
(1981)
Nature
, vol.294
, Issue.5838
, pp. 284-286
-
-
Yamamoto, H.1
Uchigata, Y.2
Okamoto, H.3
-
92
-
-
0027739947
-
Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets
-
DOI 10.1006/bbrc.1993.2641
-
Turk, J., Corbett, J. A., Ramanadham, S., Bohrer, A. and McDaniel, M. L. (1993) Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets. Biochem. Biophys. Res. Commun. 197, 1458-1464 (Pubitemid 24042786)
-
(1993)
Biochemical and Biophysical Research Communications
, vol.197
, Issue.3
, pp. 1458-1464
-
-
Turk, J.1
Corbett, J.A.2
Ramanadham, S.3
Bohrer, A.4
McDaniel, M.L.5
-
93
-
-
0025015612
-
Synthesis of 2-acetamido-2-deoxy-D-gluconhydroximolactone- and chitobionhydroximolactone-derived N-phenylcarbamates, potential inhibitors of β-N-acetylglucosaminidase
-
Beer, D., Maloisel, J.-L., Rast, D. M. and Vasella, A. (1990) Synthesis of 2-acetamido-2-deoxy-D-gluconhydroximolactone-and chitobionhydroximolactone- derived N-phenylcarbamates, potential inhibitors of N-acetylglucosaminidase? Helv. Chim. Acta 73, 1918-1922 (Pubitemid 20353197)
-
(1990)
Helvetica Chimica Acta
, vol.73
, Issue.7
, pp. 1918-1922
-
-
Beer, D.1
Maloisel, J.-L.2
Rast, D.M.3
Vasella, A.4
-
94
-
-
0032488979
-
Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-β-N- acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D- glucopyranosylidene) amino-N-phenylcarbamate
-
DOI 10.1074/jbc.273.6.3611
-
Haltiwanger, R. S., Grove, K. and Philipsberg, G. A. (1998) Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivousing the peptide O-GlcNAc-β-N-acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D-glucopyranosylidene) amino-N-phenylcarbamate. J. Biol. Chem. 273, 3611-3617 (Pubitemid 28109786)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.6
, pp. 3611-3617
-
-
Haltiwanger, R.S.1
Grove, K.2
Philipsberg, G.A.3
-
95
-
-
58049197848
-
Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance
-
Macauley, M. S., Bubb, A. K., Martinez-Fleites, C., Davies, G. J. and Vocadlo, D. J. (2008) Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance. J. Biol. Chem. 283, 34687-34695
-
(2008)
J. Biol. Chem
, vol.283
, pp. 34687-34695
-
-
Macauley, M.S.1
Bubb, A.K.2
Martinez-Fleites, C.3
Davies, G.J.4
Vocadlo, D.J.5
-
96
-
-
33845944034
-
GlcNAcstatin: A picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-GlcNAcylation levels
-
DOI 10.1021/ja066743n
-
Dorfmueller, H. C., Borodkin, V. S., Schimpl, M., Shepherd, S. M., Shpiro, N. A. and van Aalten, D. M. F. (2006) GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-GlcNAcylation levels. J. Am. Chem. Soc. 128, 16484-16485 (Pubitemid 46032711)
-
(2006)
Journal of the American Chemical Society
, vol.128
, Issue.51
, pp. 16484-16485
-
-
Dorfmueller, H.C.1
Borodkin, V.S.2
Schimpl, M.3
Shepherd, S.M.4
Shpiro, N.A.5
Van Aalten, D.M.F.6
-
97
-
-
84859361229
-
PUGNAc treatment leads to an unusual accumulation of free oligosaccharides in CHO cells
-
Mehdy, A., Morelle, W., Rosnoblet, C., Legrand, D., Lefebvre, T., Duvet, S. and Foulquier, F. (2012) PUGNAc treatment leads to an unusual accumulation of free oligosaccharides in CHO cells. J. Biochem. 151, 439-446
-
(2012)
J. Biochem
, vol.151
, pp. 439-446
-
-
Mehdy, A.1
Morelle, W.2
Rosnoblet, C.3
Legrand, D.4
Lefebvre, T.5
Duvet, S.6
Foulquier, F.7
-
98
-
-
33750243765
-
Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor
-
DOI 10.1039/b612154c
-
Shanmugasundaram, B., Debowski, A. W., Dennis, R. J., Davies, G. J., Vocadlo, D. J. and Vasella, A. (2006) Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor. Chem. Commun. 10, 4372-4374 (Pubitemid 44611693)
-
(2006)
Chemical Communications
, Issue.42
, pp. 4372-4374
-
-
Shanmugasundaram, B.1
Debowski, A.W.2
Dennis, R.J.3
Davies, G.J.4
Vocadlo, D.J.5
Vasella, A.6
-
99
-
-
30544433196
-
Engineering and characterization of a superfolder green fluorescent protein
-
DOI 10.1038/nbt1172, PII NBT1172
-
Pédelacq, J.-D., Cabantous, S., Tran, T., Terwilliger, T. C. and Waldo, G. S. (2006) Engineering and characterization of a superfolder green fluorescent protein. Nat. Biotechnol. 24, 79-88 (Pubitemid 43083170)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.1
, pp. 79-88
-
-
Pedelacq, J.-D.1
Cabantous, S.2
Tran, T.3
Terwilliger, T.C.4
Waldo, G.S.5
-
100
-
-
0029947945
-
NAG-thiazoline, an N-acetyl-β-hexosaminidase inhibitor that implicates acetamido participation
-
DOI 10.1021/ja960826u
-
Knapp, S., Vocadlo, D. J., Gao, Z., Kirk, B., Lou, J. and Withers, S. G. (1996) NAG-thiazoline, an N-acetyl-β-hexosaminidase inhibitor that implicates acetamido participation. J. Am. Chem. Soc. 118, 6804-6805 (Pubitemid 26248188)
-
(1996)
Journal of the American Chemical Society
, vol.118
, Issue.28
, pp. 6804-6805
-
-
Knapp, S.1
Vocadlo, D.2
Gao, Z.3
Kirk, B.4
Lou, J.5
Withers, S.G.6
-
101
-
-
0037117511
-
Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes
-
DOI 10.1073/pnas.072072399
-
Vosseller, K., Wells, L., Lane, M. D. and Hart, G. W. (2002) Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes. Proc. Natl. Acad. Sci. U. S. A. 99, 5313-8 (Pubitemid 34411545)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.8
, pp. 5313-5318
-
-
Vosseller, K.1
Wells, L.2
Lane, M.D.3
Hart, G.W.4
-
102
-
-
47249102179
-
Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2
-
Champattanachai, V., Marchase, R. B. and Chatham, J. C. (2008) Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2. Am. J. Physiol. Cell Physiol. 294, C1509-C1520
-
(2008)
Am. J. Physiol. Cell Physiol
, vol.294
-
-
Champattanachai, V.1
Marchase, R.B.2
Chatham, J.C.3
-
103
-
-
77952429792
-
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
-
Caldwell, S. A., Jackson, S. R., Shahriari, K. S., Lynch, T. P., Sethi, G., Walker, S., Vosseller, K. and Reginato, M. J. (2010) Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1. Oncogene 29, 2831-2842
-
(2010)
Oncogene
, vol.29
, pp. 2831-2842
-
-
Caldwell, S.A.1
Jackson, S.R.2
Shahriari, K.S.3
Lynch, T.P.4
Sethi, G.5
Walker, S.6
Vosseller, K.7
Reginato, M.J.8
-
104
-
-
47649114560
-
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
-
Yuzwa, S. A., Macauley, M. S., Heinonen, J. E., Shan, X., Dennis, R. J., He, Y., Whitworth, G. E., Stubbs, K. A., McEachern, E. J., Davies, G. J. et al. (2008) A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. Nat. Chem. Biol. 4, 483-490
-
(2008)
Nat. Chem. Biol
, vol.4
, pp. 483-490
-
-
Yuzwa, S.A.1
Macauley, M.S.2
Heinonen, J.E.3
Shan, X.4
Dennis, R.J.5
He, Y.6
Whitworth, G.E.7
Stubbs, K.A.8
McEachern, E.J.9
Davies, G.J.10
-
105
-
-
84859819548
-
Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation
-
Yu, Y., Zhang, L., Li, X., Run, X., Liang, Z., Li, Y., Liu, Y., Lee, M. H., Grundke-Iqbal, I., Iqbal, K. et al. (2012) Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation. PLoS ONE 7, e35277
-
(2012)
PLoS ONE
, vol.7
-
-
Yu, Y.1
Zhang, L.2
Li, X.3
Run, X.4
Liang, Z.5
Li, Y.6
Liu, Y.7
Lee, M.H.8
Grundke-Iqbal, I.9
Iqbal, K.10
-
106
-
-
80053280712
-
O-linked β-N-acetylglucosamine supports p38 MAPK activation by high glucose in glomerular mesangial cells
-
Goldberg, H., Whiteside, C. and Fantus, I. G. (2011) O-linked β-N-acetylglucosamine supports p38 MAPK activation by high glucose in glomerular mesangial cells. Am. J. Physiol. Endocrinol. Metab. 301, E713-E726
-
(2011)
Am. J. Physiol. Endocrinol. Metab
, vol.301
-
-
Goldberg, H.1
Whiteside, C.2
Fantus, I.G.3
-
107
-
-
79751525993
-
O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy
-
Mi, W., Gu, Y., Han, C., Liu, H., Fan, Q., Zhang, X., Cong, Q. and Yu, W. (2011) O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy. Biochim. Biophys. Acta 1812, 514-519
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 514-519
-
-
Mi, W.1
Gu, Y.2
Han, C.3
Liu, H.4
Fan, Q.5
Zhang, X.6
Cong, Q.7
Yu, W.8
-
108
-
-
66549119673
-
GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation
-
Dorfmueller, H. C., Borodkin, V. S., Schimpl, M. and van Aalten, D. M. F. (2009) GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation. Biochem. J. 420, 221-227
-
(2009)
Biochem. J
, vol.420
, pp. 221-227
-
-
Dorfmueller, H.C.1
Borodkin, V.S.2
Schimpl, M.3
Van Aalten, D.M.F.4
-
109
-
-
84858795203
-
O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release
-
Pathak, S., Borodkin, V. S., Albarbarawi, O., Campbell, D. G., Ibrahim, A. and van Aalten, D. M. (2012) O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release. EMBO J. 31, 1394-1404
-
(2012)
EMBO J
, vol.31
, pp. 1394-1404
-
-
Pathak, S.1
Borodkin, V.S.2
Albarbarawi, O.3
Campbell, D.G.4
Ibrahim, A.5
Van Aalten, D.M.6
-
110
-
-
77956392832
-
An efficient and versatile synthesis of GlcNAcstatins-potent and selective O-GlcNAcase inhibitors built on the tetrahydroimidazo[1, 2-A]pyridine scaffold
-
Borodkin, V. S. and van Aalten, D. M. F. (2010) An efficient and versatile synthesis of GlcNAcstatins-potent and selective O-GlcNAcase inhibitors built on the tetrahydroimidazo[1, 2-a]pyridine scaffold. Tetrahedron 66, 7838-7849
-
(2010)
Tetrahedron
, vol.66
, pp. 7838-7849
-
-
Borodkin, V.S.1
Van Aalten, D.M.F.2
-
111
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., Reddy, H., Caivano, M. and Cohen, P. (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105
-
(2000)
Biochem. J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
112
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., McLauchlan, H., Klevernic, I., Arthur, J. S. C., Alessi, D. R. and Cohen, P. (2007) The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408, 297-315
-
(2007)
Biochem. J
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.C.8
Alessi, D.R.9
Cohen, P.10
-
113
-
-
0037392942
-
The specificities of protein kinase inhibitors: An update
-
DOI 10.1042/BJ20021535
-
Bain, J., McLauchlan, H., Elliott, M. and Cohen, P. (2003) The specificities of protein kinase inhibitors: an update. Biochem. J. 371, 199-204 (Pubitemid 36458094)
-
(2003)
Biochemical Journal
, vol.371
, Issue.1
, pp. 199-204
-
-
Bain, J.1
McLauchlan, H.2
Elliott, M.3
Cohen, P.4
-
114
-
-
9444252281
-
Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1
-
DOI 10.2337/diabetes.53.12.3184
-
Majumdar, G., Wright, J., Markowitz, P., Martinez-Hernandez, A., Raghow, R. and Solomon, S. S. (2004) Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1. Diabetes 53, 3184-3192 (Pubitemid 39564494)
-
(2004)
Diabetes
, vol.53
, Issue.12
, pp. 3184-3192
-
-
Majumdar, G.1
Wright, J.2
Markowitz, P.3
Martinez-Hernandez, A.4
Raghow, R.5
Solomon, S.S.6
-
115
-
-
33745049963
-
Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity
-
DOI 10.1038/nsmb1079, PII N1079
-
Dennis, R. J., Taylor, E. J., Macauley, M. S., Stubbs, K. A., Turkenburg, J. P., Hart, S. J., Black, G. N., Vocadlo, D. J. and Davies, G. J. (2006) Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity. Nat. Struct. Mol. Biol. 13, 365-371 (Pubitemid 43873509)
-
(2006)
Nature Structural and Molecular Biology
, vol.13
, Issue.4
, pp. 365-371
-
-
Dennis, R.J.1
Taylor, E.J.2
MacAuley, M.S.3
Stubbs, K.A.4
Turkenburg, J.P.5
Hart, S.J.6
Black, G.N.7
Vocadlo, D.J.8
Davies, G.J.9
-
116
-
-
79955932260
-
Design and synthesis of O-GlcNAcase inhibitors via 'click chemistry' and biological evaluations
-
Li, T., Guo, L., Zhang, Y., Wang, J., Li, Z., Lin, L., Zhang, Z., Li, L., Lin, J., Zhao, W. et al. (2011) Design and synthesis of O-GlcNAcase inhibitors via 'click chemistry' and biological evaluations. Carbohydr. Res. 346, 1083-1092
-
(2011)
Carbohydr. Res
, vol.346
, pp. 1083-1092
-
-
Li, T.1
Guo, L.2
Zhang, Y.3
Wang, J.4
Li, Z.5
Lin, L.6
Zhang, Z.7
Li, L.8
Lin, J.9
Zhao, W.10
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