메뉴 건너뛰기




Volumn 73, Issue 16, 2013, Pages 5277-5287

O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 ADAMANTYLETHYL) 2 [(4 CHLOROPHENYL)AZAMETHYLENE] 4 OXO 1,3 THIAZAPERHYDROINE 6 CARBOXYLIC ACID; GLYCOSYLTRANSFERASE INHIBITOR; HEXOSAMINE; MESSENGER RNA; MYC PROTEIN; N ACETYLGLUCOSAMINYLTRANSFERASE; SMALL INTERFERING RNA; ST 045849; UNCLASSIFIED DRUG;

EID: 84882607514     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0549     Document Type: Article
Times cited : (236)

References (48)
  • 2
    • 79960071366 scopus 로고    scopus 로고
    • The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
    • Massie CE, Lynch A, Ramos-Montoya A, Boren J, Stark R, Fazli L, et al. The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. EMBO J 2011;30:2719-33.
    • (2011) EMBO J , vol.30 , pp. 2719-2733
    • Massie, C.E.1    Lynch, A.2    Ramos-Montoya, A.3    Boren, J.4    Stark, R.5    Fazli, L.6
  • 3
    • 79551469518 scopus 로고    scopus 로고
    • Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose- 26-bisphosphatase 2 in prostate cancer cells
    • Moon JS, Jin WJ, Kwak JH, Kim HJ, Yun MJ, Kim JW, et al. Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose- 2,6-bisphosphatase 2 in prostate cancer cells. Biochem J 2011;433: 225-33.
    • (2011) Biochem J , vol.433 , pp. 225-233
    • Moon, J.S.1    Jin, W.J.2    Kwak, J.H.3    Kim, H.J.4    Yun, M.J.5    Kim, J.W.6
  • 4
    • 84858796367 scopus 로고    scopus 로고
    • A two-way street: Reciprocal regulation of metabolism and signalling
    • Wellen KE, Thompson CB. A two-way street: reciprocal regulation of metabolism and signalling. Nat Rev Mol Cell Biol 2012;13:270-6.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 270-276
    • Wellen, K.E.1    Thompson, C.B.2
  • 5
    • 78650181190 scopus 로고    scopus 로고
    • The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
    • Wellen KE, Lu C, Mancuso A, Lemons JM, Ryczko M, Dennis JW, et al. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes Dev 2010;24: 2784-99.
    • (2010) Genes Dev , vol.24 , pp. 2784-2799
    • Wellen, K.E.1    Lu, C.2    Mancuso, A.3    Lemons, J.M.4    Ryczko, M.5    Dennis, J.W.6
  • 6
    • 84860184939 scopus 로고    scopus 로고
    • Bittersweet memories: Linking metabolism to epigenetics through O-GlcNAcylation
    • Hanover JA, Krause MW, Love DC. Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation. Nat Rev Mol Cell Biol 2012;13:312-21.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 312-321
    • Hanover, J.A.1    Krause, M.W.2    Love, D.C.3
  • 7
    • 77949769388 scopus 로고    scopus 로고
    • O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
    • Butkinaree C, Park K, Hart GW. O-linked beta-N-acetylglucosamine (O-GlcNAc): extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim Biophys Acta 2010;1800:96-106.
    • (2010) Biochim Biophys Acta , vol.1800 , pp. 96-106
    • Butkinaree, C.1    Park, K.2    Hart, G.W.3
  • 8
    • 79551661274 scopus 로고    scopus 로고
    • OGlcNAc transferase catalyzes site-specific proteolysis of HCF-1
    • Capotosti F, Guernier S, Lammers F, Waridel P, Cai Y, Jin J, et al. OGlcNAc transferase catalyzes site-specific proteolysis of HCF-1. Cell 2011;144:376-88.
    • (2011) Cell , vol.144 , pp. 376-388
    • Capotosti, F.1    Guernier, S.2    Lammers, F.3    Waridel, P.4    Cai, Y.5    Jin, J.6
  • 9
    • 84860184939 scopus 로고    scopus 로고
    • Bittersweet memories: Linking metabolism to epigenetics through O-GlcNAcylation
    • Hanover JA, Krause MW, Love DC. Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation. Nat Rev Mol Cell Biol 2012;13:312-21.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 312-321
    • Hanover, J.A.1    Krause, M.W.2    Love, D.C.3
  • 10
    • 77951904644 scopus 로고    scopus 로고
    • Protein O-GlcNAcylation a critical regulator of the cellular response to stress
    • Chatham JC, Marchase RB. Protein O-GlcNAcylation: a critical regulator of the cellular response to stress. Curr Signal Transduct Ther 2010;5:49-59.
    • (2010) Curr Signal Transduct Ther , vol.5 , pp. 49-59
    • Chatham, J.C.1    Marchase, R.B.2
  • 11
    • 77952429792 scopus 로고    scopus 로고
    • Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
    • Caldwell SA, Jackson SR, Shahriari KS, Lynch TP, Sethi G, Walker S, et al. Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1. Oncogene 2010;29:2831-42.
    • (2010) Oncogene , vol.29 , pp. 2831-2842
    • Caldwell, S.A.1    Jackson, S.R.2    Shahriari, K.S.3    Lynch, T.P.4    Sethi, G.5    Walker, S.6
  • 12
    • 79751525993 scopus 로고    scopus 로고
    • O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy
    • Mi W, Gu Y, Han C, Liu H, Fan Q, Zhang X, et al. O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy. Biochim Biophys Acta 2011;1812:514-9.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 514-519
    • Mi, W.1    Gu, Y.2    Han, C.3    Liu, H.4    Fan, Q.5    Zhang, X.6
  • 14
    • 57749108319 scopus 로고    scopus 로고
    • Clinical significance of p53 alterations in surgically treated prostate cancers
    • SchlommT, Iwers L, Kirstein P, Jessen B, Kollermann J, Minner S, et al. Clinical significance of p53 alterations in surgically treated prostate cancers. Mod Pathol 2008;21:1371-8.
    • (2008) Mod Pathol , vol.21 , pp. 1371-1378
    • Schlommt Iwers, L.1    Kirstein, P.2    Jessen, B.3    Kollermann, J.4    Minner, S.5
  • 15
    • 0036313566 scopus 로고    scopus 로고
    • Tumour grade, proliferation, apoptosis, microvessel density, p53, and bcl-2 in prostate cancers: Differences between tumours located in the transition zone and in the peripheral zone
    • Erbersdobler A, Fritz H, Schnoger S, Graefen M, Hammerer P, Huland H, et al. Tumour grade, proliferation, apoptosis, microvessel density, p53, and bcl-2 in prostate cancers: differences between tumours located in the transition zone and in the peripheral zone. Eur Urol 2002;41:40-6.
    • (2002) Eur Urol , vol.41 , pp. 40-46
    • Erbersdobler, A.1    Fritz, H.2    Schnoger, S.3    Graefen, M.4    Hammerer, P.5    Huland, H.6
  • 16
    • 0033557839 scopus 로고    scopus 로고
    • Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays
    • Bubendorf L, Kononen J, Koivisto P, Schraml P, Moch H, Gasser TC, et al. Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays. Cancer Res 1999;59:803-6.
    • (1999) Cancer Res , vol.59 , pp. 803-806
    • Bubendorf, L.1    Kononen, J.2    Koivisto, P.3    Schraml, P.4    Moch, H.5    Gasser, T.C.6
  • 17
    • 77649108628 scopus 로고    scopus 로고
    • Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer
    • Minner S, Jessen B, Stiedenroth L, Burandt E, Kollermann J, Mirlacher M, et al. Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer. Clin Cancer Res 2010;16:1553-60.
    • (2010) Clin Cancer Res , vol.16 , pp. 1553-1560
    • Minner, S.1    Jessen, B.2    Stiedenroth, L.3    Burandt, E.4    Kollermann, J.5    Mirlacher, M.6
  • 18
    • 27144455345 scopus 로고    scopus 로고
    • Discovery of O-GlcNAc transferase inhibitors
    • Gross BJ, Kraybill BC, Walker S. Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc 2005;127:14588-9.
    • (2005) J Am Chem Soc , vol.127 , pp. 14588-14589
    • Gross, B.J.1    Kraybill, B.C.2    Walker, S.3
  • 19
    • 79551501346 scopus 로고    scopus 로고
    • O-GlcNAcylation contributes to the vascular effects of ET-1 via activation of the RhoA/Rho-kinase pathway
    • Lima VV, Giachini FR, Carneiro FS, Carvalho MH, Fortes ZB, Webb RC, et al. O-GlcNAcylation contributes to the vascular effects of ET-1 via activation of the RhoA/Rho-kinase pathway. Cardiovasc Res 2011;89: 614-22.
    • (2011) Cardiovasc Res , vol.89 , pp. 614-622
    • Lima, V.V.1    Giachini, F.R.2    Carneiro, F.S.3    Carvalho, M.H.4    Fortes, Z.B.5    Webb, R.C.6
  • 21
    • 77952103123 scopus 로고    scopus 로고
    • An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression
    • Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang X, et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 2010;17:443-54.
    • (2010) Cancer Cell , vol.17 , pp. 443-454
    • Yu, J.1    Mani, R.S.2    Cao, Q.3    Brenner, C.J.4    Cao, X.5    Wang, X.6
  • 25
    • 0031431599 scopus 로고    scopus 로고
    • Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus
    • Bello D, Webber MM, Kleinman HK, Wartinger DD, Rhim JS. Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus Carcinogenesis 1997;18:1215-23.
    • (1997) Carcinogenesis , vol.18 , pp. 1215-1223
    • Bello, D.1    Webber, M.M.2    Kleinman, H.K.3    Wartinger, D.D.4    Rhim, J.S.5
  • 26
    • 84859484538 scopus 로고    scopus 로고
    • Critical role of O-Linked beta-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis
    • Lynch TP, Ferrer CM, Jackson SR, Shahriari KS, Vosseller K, Reginato MJ. Critical role of O-Linked beta-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis. J Biol Chem 2012;287:11070-81.
    • (2012) J Biol Chem , vol.287 , pp. 11070-11081
    • Lynch, T.P.1    Ferrer, C.M.2    Jackson, S.R.3    Shahriari, K.S.4    Vosseller, K.5    Reginato, M.J.6
  • 27
    • 84863610013 scopus 로고    scopus 로고
    • Evidence of the involvement of O-GlcNAc-modified humanRNApolymerase IICTD in transcription in vitro and in vivo
    • Ranuncolo SM, Ghosh S, Hanover JA, Hart GW, Lewis BA. Evidence of the involvement of O-GlcNAc-modified humanRNApolymerase IICTD in transcription in vitro and in vivo. J Biol Chem 2012;287:23549-61.
    • (2012) J Biol Chem , vol.287 , pp. 23549-23561
    • Ranuncolo, S.M.1    Ghosh, S.2    Hanover, J.A.3    Hart, G.W.4    Lewis, B.A.5
  • 28
    • 84867551392 scopus 로고    scopus 로고
    • Landmarks in hormonal therapy for prostate cancer
    • Hammerer P, Madersbacher S. Landmarks in hormonal therapy for prostate cancer. BJU Int 2012;110 Suppl 1:23-9.
    • (2012) BJU Int , vol.110 , Issue.SUPPL. 1 , pp. 23-29
    • Hammerer, P.1    Madersbacher, S.2
  • 29
    • 78649894035 scopus 로고    scopus 로고
    • O-linked beta- N-acetylglucosamine (O-GlcNAc) regulates stress-induced heat shock protein expression in a GSK-3beta-dependent manner
    • Kazemi Z, Chang H, Haserodt S,McKen C, Zachara NE. O-linked beta- N-acetylglucosamine (O-GlcNAc) regulates stress-induced heat shock protein expression in a GSK-3beta-dependent manner. J Biol Chem 2010;285:39096-107.
    • (2010) J Biol Chem , vol.285 , pp. 39096-39107
    • Kazemi, Z.1    Chang, H.2    Haserodt Smcken, C.3    Zachara, N.E.4
  • 30
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009;4:44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 31
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da W, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009;37:1-13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 33
    • 0029049198 scopus 로고
    • C-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas
    • Chou TY, Hart GW, Dang CV. c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J Biol Chem 1995;270:18961-5.
    • (1995) J Biol Chem , vol.270 , pp. 18961-18965
    • Chou, T.Y.1    Hart, G.W.2    Dang, C.V.3
  • 35
    • 74949116742 scopus 로고    scopus 로고
    • Chromosome 8p deletions and 8q gains are associated with tumor progression and poor prognosis in prostate cancer
    • El Gammal AT, Bruchmann M, Zustin J, Isbarn H, Hellwinkel OJ, Kollermann J, et al. Chromosome 8p deletions and 8q gains are associated with tumor progression and poor prognosis in prostate cancer. Clin Cancer Res 2010;16:56-64.
    • (2010) Clin Cancer Res , vol.16 , pp. 56-64
    • El Gammal, A.T.1    Bruchmann, M.2    Zustin, J.3    Isbarn, H.4    Hellwinkel, O.J.5    Kollermann, J.6
  • 36
    • 84860321700 scopus 로고    scopus 로고
    • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
    • Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher- Sananikone E, et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell 2012;149: 656-70.
    • (2012) Cell , vol.149 , pp. 656-670
    • Ying, H.1    Kimmelman, A.C.2    Lyssiotis, C.A.3    Hua, S.4    Chu, G.C.5    Fletcher-Sananikone, E.6
  • 39
    • 50249133616 scopus 로고    scopus 로고
    • Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
    • Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, et al. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod Pathol 2008;21:1156-67.
    • (2008) Mod Pathol , vol.21 , pp. 1156-1167
    • Gurel, B.1    Iwata, T.2    Koh, C.M.3    Jenkins, R.B.4    Lan, F.5    Van Dang, C.6
  • 40
    • 33745239261 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization analysis of c-myc amplification in stage TNM prostate cancer in Japanese patients
    • Sato H, Minei S, Hachiya T, Yoshida T, Takimoto Y. Fluorescence in situ hybridization analysis of c-myc amplification in stage TNM prostate cancer in Japanese patients. Int J Urol 2006;13:761-6.
    • (2006) Int J Urol , vol.13 , pp. 761-766
    • Sato, H.1    Minei, S.2    Hachiya, T.3    Yoshida, T.4    Takimoto, Y.5
  • 41
    • 0022552440 scopus 로고
    • Expression of the c-myc protooncogene in human prostatic carcinoma and benign prostatic hyperplasia
    • Fleming WH, Hamel A, MacDonald R, Ramsey E, Pettigrew NM, Johnston B, et al. Expression of the c-myc protooncogene in human prostatic carcinoma and benign prostatic hyperplasia. Cancer Res 1986;46:1535-8.
    • (1986) Cancer Res , vol.46 , pp. 1535-1538
    • Fleming, W.H.1    Hamel, A.2    Macdonald, R.3    Ramsey, E.4    Pettigrew, N.M.5    Johnston, B.6
  • 42
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson AG Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 1971;68:820-3.
    • (1971) Proc Natl Acad Sci U S A , vol.68 , pp. 820-823
    • Knudson Jr., A.G.1
  • 45
    • 80055000824 scopus 로고    scopus 로고
    • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
    • Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 2011;478:524-8.
    • (2011) Nature , vol.478 , pp. 524-528
    • Zuber, J.1    Shi, J.2    Wang, E.3    Rappaport, A.R.4    Herrmann, H.5    Sison, E.A.6
  • 46
    • 41549090369 scopus 로고    scopus 로고
    • Multiple pathways regulated by the tumor suppressor PP2A in transformation
    • Westermarck J, HahnWC. Multiple pathways regulated by the tumor suppressor PP2A in transformation. Trends Mol Med 2008;14: 152-60.
    • (2008) Trends Mol Med , vol.14 , pp. 152-160
    • Westermarck, J.1    Hahn, W.C.2
  • 47
    • 2942735131 scopus 로고    scopus 로고
    • SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase
    • Cheng J, Wang D, Wang Z, Yeh ET. SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase Mol Cell Biol 2004;24:6021-8.
    • (2004) Mol Cell Biol , vol.24 , pp. 6021-6028
    • Cheng, J.1    Wang, D.2    Wang, Z.3    Yeh, E.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.