A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase

Nature Chemical Biology

Volumn 8, Issue 1, 2012, Pages 72-77

  Jiang, Jiaoyang ^a   Lazarus, Michael B ^a,b   Pasquina, Lincoln ^a   Sliz, Piotr ^a,c   Walker, Suzanne ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMIC ACID DERIVATIVE; CARBONYL DERIVATIVE; CYSTEINE; GLYCOSYLTRANSFERASE; LYSINE; NUCLEOTIDE; O LINKED N ACETYLGLUCOSAMINE TRANSFERASE; PYROPHOSPHATE; SCAFFOLD PROTEIN; SUGAR; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CROSS LINKING; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; ENZYME SUBSTRATE; HUMAN; INTRACELLULAR SIGNALING; MOLECULAR MIMICRY; PRIORITY JOURNAL; PROTEIN PROCESSING;

EID: 83655163673     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.711     Document Type: Article

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