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Volumn 425, Issue 1, 2010, Pages 53-54

Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation

Author keywords

Cell regulation; Chemical biology; Chemical inhibitor; Protein kinase; Signal transduction

Indexed keywords

CELL REGULATION; CELL-PERMEABLE; CELLULAR REGULATION; CHEMICAL BIOLOGY; CHEMICAL INHIBITOR; CHEMICAL INHIBITORS; IN-CELL; PROTEIN FUNCTIONS; PROTEIN KINASE INHIBITORS;

EID: 72449192809     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20091428     Document Type: Review
Times cited : (59)

References (6)
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    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies, S. P., Reddy, H., Caivano, M. and Cohen, P. (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105
    • (2000) Biochem. J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 2
    • 0037392942 scopus 로고    scopus 로고
    • The specificities of protein kinases: An update
    • Bain, J., McLauchlan, H., Elliott, M. and Cohen, P. (2003) The specificities of protein kinases: an update. Biochem. J. 371, 199-204
    • (2003) Biochem. J , vol.371 , pp. 199-204
    • Bain, J.1    McLauchlan, H.2    Elliott, M.3    Cohen, P.4
  • 5
    • 0032901378 scopus 로고    scopus 로고
    • Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB203580
    • Eyers, P. A., van den Ijssel, P., Quinlan, R., Goedert, M. and Cohen, P. (1999) Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB203580. FEBS Lett. 451, 191-196
    • (1999) FEBS Lett , vol.451 , pp. 191-196
    • Eyers, P.A.1    van den Ijssel, P.2    Quinlan, R.3    Goedert, M.4    Cohen, P.5
  • 6
    • 67650061988 scopus 로고    scopus 로고
    • Discovery and exploitation of inhibitor-resistant Aurora and Polo kinase mutants for the analysis of mitotic networks
    • Scutt, P. J., Chu, M. L. H., Sloane, D. A., Cherry, M., Bignell, C. R., Williams, D. H. and Eyers, P. A. (2009) Discovery and exploitation of inhibitor-resistant Aurora and Polo kinase mutants for the analysis of mitotic networks. J. Biol. Chem. 284, 15880-15893
    • (2009) J. Biol. Chem , vol.284 , pp. 15880-15893
    • Scutt, P.J.1    Chu, M.L.H.2    Sloane, D.A.3    Cherry, M.4    Bignell, C.R.5    Williams, D.H.6    Eyers, P.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.