Toxic effects of hyperglycemia are mediated by the hexosamine signaling pathway and O-linked glycosylation in early mouse embryos

Biology of Reproduction

Volumn 82, Issue 4, 2010, Pages 751-758

  Pantaleon, Marie ^a   Tan, Hwee Y ^a   Kafer, Georgia R ^a   Kaye, Peter L ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Apoptosis; Early development; Embryo; Embryo metabolism; Glucose signaling

Indexed keywords

HEXOSAMINE;

APOPTOSIS; ARTICLE; BLASTOCYST; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME INHIBITION; FEMALE; GLYCOSYLATION; HYPERGLYCEMIA; MOUSE; NONHUMAN; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACETYLGLUCOSAMINIDASE; ANIMALS; ANTIBODIES; CARBOHYDRATE METABOLISM; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; ENZYME ACTIVATION; FEMALE; GESTATIONAL AGE; GLYCOSYLATION; HEXOSAMINES; HYPERGLYCEMIA; MATERNAL-FETAL EXCHANGE; MICE; MODELS, BIOLOGICAL; N-ACETYLGLUCOSAMINYLTRANSFERASES; PREGNANCY; PREGNANCY COMPLICATIONS; SIGNAL TRANSDUCTION;

EID: 77953864480     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.076661     Document Type: Article

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