DNA damage signaling, impairment of cell cycle progression, and apoptosis triggered by 5-ethynyl-2′-deoxyuridine incorporated into DNA

Cytometry Part A

Volumn 83, Issue 11, 2013, Pages 979-988

  Zhao, Hong ^a   Halicka, H Dorota ^a   Li, Jiangwei ^a   Biela, Ewa ^b   Berniak, Krzysztof ^b   Dobrucki, Jurek ^b   Darzynkiewicz, Zbigniew ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

H2AX foci; ATM activation; Caspase 3 activation; Chk2 activation; Click chemistry; Confocal microscopy; DNA strand breaks; Flow cytometry; Laser scanning cytometry; P53 activation; P53BP1 foci; SBIP methodology

Indexed keywords

5 ETHYNYLDEOXYURIDINE; 5-ETHYNYL-2'-DEOXYURIDINE; DEOXYURIDINE; DNA; DRUG DERIVATIVE; H2AFX PROTEIN, HUMAN; HISTONE; PROTEIN P53; TP53 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; ATM ACTIVATION; CASPASE-3 ACTIVATION; CELL CYCLE; CHEMISTRY; CHK2 ACTIVATION; CLICK CHEMISTRY; CONFOCAL MICROSCOPY; DNA DAMAGE; DNA STRAND BREAKS; DRUG EFFECT; FLOW CYTOMETRY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; LASER SCANNING CYTOMETRY; METHODOLOGY; P53 ACTIVATION; P53BP1 FOCI; SBIP METHODOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; ΓH2AX FOCI;

ATM ACTIVATION; CASPASE-3 ACTIVATION; CHK2 ACTIVATION; CLICK CHEMISTRY; CONFOCAL MICROSCOPY; DNA STRAND BREAKS; FLOW CYTOMETRY; LASER SCANNING CYTOMETRY; P53 ACTIVATION; P53BP1 FOCI; SBIP METHODOLOGY; ΓH2AX FOCI;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CLICK CHEMISTRY; DEOXYURIDINE; DNA; DNA DAMAGE; HISTONES; HUMANS; LASER SCANNING CYTOMETRY; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84886439987     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.22396     Document Type: Article

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