메뉴 건너뛰기




Volumn 10, Issue 8, 2008, Pages 804-816

Bromodeoxyuridine inhibits cancer cel proliferation in vitro and in vivo

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; DNA;

EID: 48249128041     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.08382     Document Type: Article
Times cited : (39)

References (58)
  • 1
    • 0345494937 scopus 로고
    • Mode of action of 5-bromodeoxyuridine on mammalian cells in culture
    • Hakala MT (1959). Mode of action of 5-bromodeoxyuridine on mammalian cells in culture. J Biol Chem 234, 3072-3076.
    • (1959) J Biol Chem , vol.234 , pp. 3072-3076
    • Hakala, M.T.1
  • 2
    • 48249083670 scopus 로고
    • Effect of 5-bromodeoxyuridine incorporation on survival of cultured mammalian cells
    • Hakala MT (1962). Effect of 5-bromodeoxyuridine incorporation on survival of cultured mammalian cells. Biochim Biophys Acta 61, 815-823.
    • (1962) Biochim Biophys Acta , vol.61 , pp. 815-823
    • Hakala, M.T.1
  • 3
    • 0001330427 scopus 로고
    • Genetics of human cell lines: III. Incorporation of 5-bromo- and 5-iododeoxyuridine into the deoxyribonucleic acid of human cells and its effect on radiation sensitivity
    • Djordjevic B and Szybalski W (1960). Genetics of human cell lines: III. Incorporation of 5-bromo- and 5-iododeoxyuridine into the deoxyribonucleic acid of human cells and its effect on radiation sensitivity. J Exp Med 112, 509-531.
    • (1960) J Exp Med , vol.112 , pp. 509-531
    • Djordjevic, B.1    Szybalski, W.2
  • 4
    • 7144226522 scopus 로고
    • The toxic effect of 5-bromodeoxyuridine on cultured epithelial cells
    • Littlefield JW and Gould EA (1959). The toxic effect of 5-bromodeoxyuridine on cultured epithelial cells. J Biol Chem 235, 1129-1133.
    • (1959) J Biol Chem , vol.235 , pp. 1129-1133
    • Littlefield, J.W.1    Gould, E.A.2
  • 5
    • 0015069175 scopus 로고
    • Differential effect of 5-bromodeoxyuridine on the concentrations of specific enzymes in hepatoma cells in culture
    • Stellwagen RH and Tomkins GM (1971). Differential effect of 5-bromodeoxyuridine on the concentrations of specific enzymes in hepatoma cells in culture. Proc Natl Acad Sci USA 68, 1147-1150.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 1147-1150
    • Stellwagen, R.H.1    Tomkins, G.M.2
  • 6
    • 0003240684 scopus 로고
    • Effects of 5-halogenated uracils on the growth of Eschericia coli and their incorporation into deoxyribonucleic acids
    • Dunn DB and Smith JD (1957). Effects of 5-halogenated uracils on the growth of Eschericia coli and their incorporation into deoxyribonucleic acids. Biochem J 67, 494-506.
    • (1957) Biochem J , vol.67 , pp. 494-506
    • Dunn, D.B.1    Smith, J.D.2
  • 7
    • 48249102558 scopus 로고
    • The mechanism of 5-bromouracil mutagenesis in the bacteriophage T4
    • Terzaghi BE, Streisinger G, and Stahl FW (1962). The mechanism of 5-bromouracil mutagenesis in the bacteriophage T4. Proc Natl Acad Sci USA 48, 1519-1524.
    • (1962) Proc Natl Acad Sci USA , vol.48 , pp. 1519-1524
    • Terzaghi, B.E.1    Streisinger, G.2    Stahl, F.W.3
  • 8
    • 0035833068 scopus 로고    scopus 로고
    • Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
    • Cameron HA and McKay RD (2001). Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 435, 406-417.
    • (2001) J Comp Neurol , vol.435 , pp. 406-417
    • Cameron, H.A.1    McKay, R.D.2
  • 9
    • 0033381225 scopus 로고    scopus 로고
    • 5-Bromodeoxyuridine induces senescence-like phenomena in mammalian cells regardless of cell type or species
    • Michishita E, Nakabayashi K, Suzuki T, Kaul SC, Ogino H, Fujii M, Mitsui Y, and Ayusawa D (1999). 5-Bromodeoxyuridine induces senescence-like phenomena in mammalian cells regardless of cell type or species. J Biochem 126, 1052-1059.
    • (1999) J Biochem , vol.126 , pp. 1052-1059
    • Michishita, E.1    Nakabayashi, K.2    Suzuki, T.3    Kaul, S.C.4    Ogino, H.5    Fujii, M.6    Mitsui, Y.7    Ayusawa, D.8
  • 11
    • 33845209203 scopus 로고    scopus 로고
    • BrdU immunohistochemistry for studying adult neurogenesis: Paradigms, pitfalls, limitations, and validation
    • Taupin P (2006). BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation. Brain Res Rev 53, 198-214.
    • (2006) Brain Res Rev , vol.53 , pp. 198-214
    • Taupin, P.1
  • 12
    • 0000961718 scopus 로고
    • Effect of 5-bromodeoxyuridine on mammalian chromosomes
    • Hsu TC and Somers CE (1961). Effect of 5-bromodeoxyuridine on mammalian chromosomes. Proc Natl Acad Sci USA 47, 396-403.
    • (1961) Proc Natl Acad Sci USA , vol.47 , pp. 396-403
    • Hsu, T.C.1    Somers, C.E.2
  • 13
    • 84883837920 scopus 로고
    • Molecular radiobiology of human cell lines: V. Comparative radiosensitizing properties of 5-halodeoxycytidines and 5-halode-oxypyrimidines
    • Erickson RL and Szybalski W (1963). Molecular radiobiology of human cell lines: V. Comparative radiosensitizing properties of 5-halodeoxycytidines and 5-halode-oxypyrimidines. Radiat Res 20, 252-262.
    • (1963) Radiat Res , vol.20 , pp. 252-262
    • Erickson, R.L.1    Szybalski, W.2
  • 16
    • 0030692809 scopus 로고    scopus 로고
    • A phase I trial of hepatic arterial bromodeoxyuridine and conformal radiation therapy for patients with primary hepatobiliary cancers or colorectal liver metastases
    • Robertson JM, McGinn CJ, Walker S, Marx MV, Kessler ML, Ensminger WD, and Lawrence TS (1997). A phase I trial of hepatic arterial bromodeoxyuridine and conformal radiation therapy for patients with primary hepatobiliary cancers or colorectal liver metastases. Clin Invest 39, 1087-1092.
    • (1997) Clin Invest , vol.39 , pp. 1087-1092
    • Robertson, J.M.1    McGinn, C.J.2    Walker, S.3    Marx, M.V.4    Kessler, M.L.5    Ensminger, W.D.6    Lawrence, T.S.7
  • 17
    • 0030936244 scopus 로고    scopus 로고
    • A phase I trial of intravenous bromodeoxyuridine and radiation therapy for pancreatic cancer
    • Robertson JM, Ensminger WD, Walker S, and Lawrence TS (1997). A phase I trial of intravenous bromodeoxyuridine and radiation therapy for pancreatic cancer. Clin Invest 37, 331-335.
    • (1997) Clin Invest , vol.37 , pp. 331-335
    • Robertson, J.M.1    Ensminger, W.D.2    Walker, S.3    Lawrence, T.S.4
  • 18
    • 0032801217 scopus 로고    scopus 로고
    • A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme
    • Groves MD, Maor MH, Meyers C, Kyritsis AP, Jaeckle KA, Yung WK, Sawaya RE, Hess K, Bruner JM, Peterson P, et al. (1999). A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme. Clin Invest 45, 127-135.
    • (1999) Clin Invest , vol.45 , pp. 127-135
    • Groves, M.D.1    Maor, M.H.2    Meyers, C.3    Kyritsis, A.P.4    Jaeckle, K.A.5    Yung, W.K.6    Sawaya, R.E.7    Hess, K.8    Bruner, J.M.9    Peterson, P.10
  • 22
    • 27944434206 scopus 로고    scopus 로고
    • Neuron-to-astrocyte transition: Phenotypic fluidity and the formation of hybrid asterons in differentiating neurosphere
    • Laywell ED, Kearns SM, Zheng T, Chen KA, Deng J, Chen HX, Roper SN, and Steindler DA (2005). Neuron-to-astrocyte transition: phenotypic fluidity and the formation of hybrid asterons in differentiating neurosphere. J Comp Neurol 493, 321-333.
    • (2005) J Comp Neurol , vol.493 , pp. 321-333
    • Laywell, E.D.1    Kearns, S.M.2    Zheng, T.3    Chen, K.A.4    Deng, J.5    Chen, H.X.6    Roper, S.N.7    Steindler, D.A.8
  • 23
    • 33748543262 scopus 로고    scopus 로고
    • Rejection of RG-2 gliomas is mediated by microglia and T lymphocytes
    • Mariani CL, Kouri JG, and Streit WJ (2006). Rejection of RG-2 gliomas is mediated by microglia and T lymphocytes. J Neurooncol 79, 243-253.
    • (2006) J Neurooncol , vol.79 , pp. 243-253
    • Mariani, C.L.1    Kouri, J.G.2    Streit, W.J.3
  • 24
    • 18244382560 scopus 로고    scopus 로고
    • Neural stem cells and neurospheres - re-evaluating the relationship
    • Reynolds BA and Rietze RL (2005). Neural stem cells and neurospheres - re-evaluating the relationship. Nat Methods 2, 333-336.
    • (2005) Nat Methods , vol.2 , pp. 333-336
    • Reynolds, B.A.1    Rietze, R.L.2
  • 25
  • 26
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds BA and Weiss S (1992). Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255, 1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 27
    • 0036737914 scopus 로고    scopus 로고
    • Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
    • Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, and Steindler DA (2002). Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39, 193-206.
    • (2002) Glia , vol.39 , pp. 193-206
    • Ignatova, T.N.1    Kukekov, V.G.2    Laywell, E.D.3    Suslov, O.N.4    Vrionis, F.D.5    Steindler, D.A.6
  • 30
    • 0036086352 scopus 로고    scopus 로고
    • Changes in nuclear matrix proteins during the senescence-like phenomenon induced by 5-chlorodeoxyuridine in HeLa cells
    • Michishita E, Kurahashi T, Suzuki T, Fukuda M, Fujii M, Hirano H, and Ayusawa D (2002). Changes in nuclear matrix proteins during the senescence-like phenomenon induced by 5-chlorodeoxyuridine in HeLa cells. Exp Gerontol 37, 885-890.
    • (2002) Exp Gerontol , vol.37 , pp. 885-890
    • Michishita, E.1    Kurahashi, T.2    Suzuki, T.3    Fukuda, M.4    Fujii, M.5    Hirano, H.6    Ayusawa, D.7
  • 31
    • 0033603823 scopus 로고    scopus 로고
    • Annexin V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death
    • Hammill AK, Uhr JW, and Scheuermann RH (1999). Annexin V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death. Exp Cell Res 251, 16-21.
    • (1999) Exp Cell Res , vol.251 , pp. 16-21
    • Hammill, A.K.1    Uhr, J.W.2    Scheuermann, R.H.3
  • 32
    • 27844520930 scopus 로고    scopus 로고
    • Lymphoma cells protected from apoptosis by dysregulated Bcl-2 continue to bind annexin V in response to B-cell receptor engagement: A cautionary tale
    • Holder MJ, Barnes NM, Gregory CD, and Gordon J (2006). Lymphoma cells protected from apoptosis by dysregulated Bcl-2 continue to bind annexin V in response to B-cell receptor engagement: a cautionary tale. Leuk Res 30, 77-80.
    • (2006) Leuk Res , vol.30 , pp. 77-80
    • Holder, M.J.1    Barnes, N.M.2    Gregory, C.D.3    Gordon, J.4
  • 33
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA (1995). The retinoblastoma protein and cell cycle control. Cell 81, 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 34
    • 14644393641 scopus 로고    scopus 로고
    • Early BrdU-responsive genes constitute a novel class of senescence-associated genes in human cells
    • Minagawa S, Nakabayashi K, Fujii M, Scherer SW, and Ayusawa D (2005). Early BrdU-responsive genes constitute a novel class of senescence-associated genes in human cells. Exp Cell Res 304, 552-558.
    • (2005) Exp Cell Res , vol.304 , pp. 552-558
    • Minagawa, S.1    Nakabayashi, K.2    Fujii, M.3    Scherer, S.W.4    Ayusawa, D.5
  • 36
    • 33846652598 scopus 로고    scopus 로고
    • Mammalian telomeres
    • Woodbury, NY: Cold Spring Harbor Press
    • de Lange T (2006). Mammalian telomeres. Telomeres. Woodbury, NY: Cold Spring Harbor Press, 341-387.
    • (2006) Telomeres , pp. 341-387
    • de Lange, T.1
  • 38
    • 28444496362 scopus 로고    scopus 로고
    • Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila
    • Mandal S, Guptan P, Owusu-Ansah E, and Banerjee U (2005). Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila. Dev Cell 9, 843-854.
    • (2005) Dev Cell , vol.9 , pp. 843-854
    • Mandal, S.1    Guptan, P.2    Owusu-Ansah, E.3    Banerjee, U.4
  • 39
    • 0029803242 scopus 로고    scopus 로고
    • In situ localization of mitochondrial DNA replication in intact mammalian cells
    • Davis AF and Clayton DA (1996). In situ localization of mitochondrial DNA replication in intact mammalian cells. J Cell Biol 135, 883-893.
    • (1996) J Cell Biol , vol.135 , pp. 883-893
    • Davis, A.F.1    Clayton, D.A.2
  • 40
    • 0019829553 scopus 로고
    • Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance
    • Ashman CR and Davidson RL (1981). Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance. Mol Cell Biol 1, 254-260.
    • (1981) Mol Cell Biol , vol.1 , pp. 254-260
    • Ashman, C.R.1    Davidson, R.L.2
  • 41
    • 0345588030 scopus 로고
    • Bromodeoxyuridine mutagenesis in mammalian cells: Mutagenesis is independent of the amount of bromouracil in DNA
    • Kaufman ER and Davidson RL (1978). Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA. Proc Natl Acad Sci USA 75, 4982-4986.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 4982-4986
    • Kaufman, E.R.1    Davidson, R.L.2
  • 42
    • 0016150791 scopus 로고
    • Induction of a deoxycytidineless state in cultured mammalian cells by bromodeoxyuridine
    • Meuth M and Green H (1974). Induction of a deoxycytidineless state in cultured mammalian cells by bromodeoxyuridine. Cell 2, 109-112.
    • (1974) Cell , vol.2 , pp. 109-112
    • Meuth, M.1    Green, H.2
  • 43
    • 0014028008 scopus 로고
    • Regulation of mammalian deoxyribonucleotide biosynthesis by nucleotides as activators and inhibitors
    • Moore EC and Hurlbert RB (1966). Regulation of mammalian deoxyribonucleotide biosynthesis by nucleotides as activators and inhibitors. J Biol Chem 241, 4802-4809.
    • (1966) J Biol Chem , vol.241 , pp. 4802-4809
    • Moore, E.C.1    Hurlbert, R.B.2
  • 44
    • 0018894161 scopus 로고
    • Deoxyribonucleotide pools, base pairing, and sequence configuration affecting bromodeoxyuridine-and 2-aminopuridine- induced mutagenesis
    • Hopkins RL and Goodman MF(1980). Deoxyribonucleotide pools, base pairing, and sequence configuration affecting bromodeoxyuridine-and 2-aminopuridine- induced mutagenesis. Proc Natl Acad Sci USA 77, 1801-1805.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1801-1805
    • Hopkins, R.L.1    Goodman, M.F.2
  • 45
    • 0018122162 scopus 로고
    • Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by thymidine and suppressed by deoxycytidine
    • Davidson RL and Kaufman ER (1978). Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by thymidine and suppressed by deoxycytidine. Nature 276, 722-733.
    • (1978) Nature , vol.276 , pp. 722-733
    • Davidson, R.L.1    Kaufman, E.R.2
  • 46
    • 0018887347 scopus 로고
    • Morphological characterization of nitrosourea-induced glioma cell lines and clones
    • Ko L, Koestner A, and Wechsler W (1980). Morphological characterization of nitrosourea-induced glioma cell lines and clones. Acta Neuropathol 51, 23-31.
    • (1980) Acta Neuropathol , vol.51 , pp. 23-31
    • Ko, L.1    Koestner, A.2    Wechsler, W.3
  • 48
    • 0031776473 scopus 로고    scopus 로고
    • Rat brain tumor models in experimental neuro-oncology: The 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas
    • Barth RF (1998). Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas. J Neurooncol 36, 91-102.
    • (1998) J Neurooncol , vol.36 , pp. 91-102
    • Barth, R.F.1
  • 49
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J (2005). Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120, 513-522.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 50
    • 34249017255 scopus 로고    scopus 로고
    • Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: Stress-induced premature senescence does not increase effect
    • Liu D and Hornsby PJ (2007). Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect. Neoplasia 9, 418-426.
    • (2007) Neoplasia , vol.9 , pp. 418-426
    • Liu, D.1    Hornsby, P.J.2
  • 51
    • 0034713329 scopus 로고    scopus 로고
    • Is β-galactosidase staining a marker of senescence in vitro and in vivo?
    • Severino J, Allen RG, Balin S, and Cristofalo VJ (2000). Is β-galactosidase staining a marker of senescence in vitro and in vivo? Exp Cell Res 257, 162-171.
    • (2000) Exp Cell Res , vol.257 , pp. 162-171
    • Severino, J.1    Allen, R.G.2    Balin, S.3    Cristofalo, V.J.4
  • 52
    • 0141907407 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein in differentiation and senescence
    • Thomas DM, Yang H-S, Alexander K, and Hinds PW (2003). Role of the retinoblastoma protein in differentiation and senescence. Cancer Biol Ther 2, 124-130.
    • (2003) Cancer Biol Ther , vol.2 , pp. 124-130
    • Thomas, D.M.1    Yang, H.-S.2    Alexander, K.3    Hinds, P.W.4
  • 53
    • 0036545452 scopus 로고    scopus 로고
    • 5-Bromo-2′-deoxyuridine efficiently suppresses division potential of the yeast Saccharomyces cerevisiae
    • Fujii M, Ito H, Hasegawa T, Suzuki T, Adachi N, and Ayusawa D (2002). 5-Bromo-2′-deoxyuridine efficiently suppresses division potential of the yeast Saccharomyces cerevisiae. Biosci Biotechnol Biochem 66, 906-909.
    • (2002) Biosci Biotechnol Biochem , vol.66 , pp. 906-909
    • Fujii, M.1    Ito, H.2    Hasegawa, T.3    Suzuki, T.4    Adachi, N.5    Ayusawa, D.6
  • 54
    • 0036679237 scopus 로고    scopus 로고
    • Validation of the Medical Research Council and a newly developed prognostic index in patients with malignant glioma: How useful are prognostic indices in routine clinical practice?
    • Akman F, Cooper RA, Sen M, Tanriver Y, and Kentli S (2002). Validation of the Medical Research Council and a newly developed prognostic index in patients with malignant glioma: how useful are prognostic indices in routine clinical practice? J Neurooncol 59, 39-47.
    • (2002) J Neurooncol , vol.59 , pp. 39-47
    • Akman, F.1    Cooper, R.A.2    Sen, M.3    Tanriver, Y.4    Kentli, S.5
  • 56
    • 0034515477 scopus 로고    scopus 로고
    • A comparison of treatment results for recurrent malignant gliomas
    • Nieder C, Grosu AL, and Molls M (2000). A comparison of treatment results for recurrent malignant gliomas. Cancer Treat Rev 26, 397-409.
    • (2000) Cancer Treat Rev , vol.26 , pp. 397-409
    • Nieder, C.1    Grosu, A.L.2    Molls, M.3
  • 57
    • 36348942901 scopus 로고    scopus 로고
    • Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GMCSF leads to an effective anti-tumor response in subcutaneous RG-2 gliomas
    • Mariani CL, Rajon D, Bova FJ, and Streit WJ (2007). Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GMCSF leads to an effective anti-tumor response in subcutaneous RG-2 gliomas. J Neurooncol 85, 231-240.
    • (2007) J Neurooncol , vol.85 , pp. 231-240
    • Mariani, C.L.1    Rajon, D.2    Bova, F.J.3    Streit, W.J.4
  • 58


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.