Dendrimers as Transfection Agents

Dendrimers: Towards Catalytic, Material and Biomedical Uses

Volumn , Issue , 2011, Pages 413-435

  Turrin, Cédric Olivier ^a   Caminade, Anne Marie ^a  

^a LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

Author keywords

Dendrimers as transfection agents; Gene transfection with other dendrimers and gene transfection with PPI dendrimers; Gene transfection with PAMAM dendrimers popular dendrimeric vectors for gene delivery; Gene transfection, for transmission infection modification of eukaryotic cells, exogenous DNA; Gene transfection, sensitive technique to initial conditions, bound to butterfly effects; Gene transfection, two difficulties need to compact transfected gene, making penetration of cell and nucleus membranes; Gene transfection, with core modified PAMAM amine functions on dendrimers, and charge density; Polyplexes, from interaction of DNA with cationic polymers, linear structures to hyperbranched ones like polyethyleneimine (PEI); Recent advent of siRNA based strategies new perspectives for dendrimers as RNA delivery agents; Schematic representation of generation 4 PAMAM with PEG chains and targeting ligand

Indexed keywords

EID: 84886007657     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781119976530.ch17     Document Type: Chapter

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