The mechanism of polyplex internalization into cells: Testing the GM1/caveolin-1 lipid raft mediated endocytosis pathway

Molecular Pharmaceutics

Volumn 7, Issue 1, 2010, Pages 267-279

  Qi, Rong ^a,b,c,d   Mullen, Douglas G ^c,d   Baker Jr , James R ^d   Banaszak Holl, Mark M ^c,d  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Caveolin 1; Endocytosis; Ganglioside GM1; PAMAM dendrimer; Polyplexes; Transfection

Indexed keywords

1 PHENYL 2 PALMITOYL 3 MORPHOLINO 1 PROPANOL; ADENOVIRUS VECTOR; CAVEOLIN 1; CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR; CHOLERA TOXIN B SUBUNIT; DENDRIMER; GANGLIOSIDE GM1; POLYAMIDOAMINE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CELL LEVEL; CELL MEMBRANE; CELL STRAIN COS7; CELL STRAIN HEK293; CELL STRAIN HEPG2; COMPLEX FORMATION; CONTROLLED STUDY; DOT HYBRIDIZATION; ENDOCYTOSIS; GENETIC TRANSFECTION; GLIA CELL; HELA CELL; HUMAN; HUMAN CELL; INCUBATION TIME; INTERNALIZATION; LIPID RAFT; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

ADENOVIRUSES, HUMAN; ANIMALS; CAVEOLIN 1; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DENDRIMERS; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; G(M1) GANGLIOSIDE; GENETIC VECTORS; HELA CELLS; HUMANS; MEMBRANE MICRODOMAINS; MEPERIDINE; TRANSFECTION;

EID: 76249134300     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp900241t     Document Type: Article

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