Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions

Journal of Neurochemistry

Volumn 126, Issue 4, 2013, Pages 437-450

  Dal Cim, Tharine ^a   Ludka, Fabiana K ^a,b   Martins, Wagner C ^a   Reginato, Charlise ^a   Parada, Esther ^c   Egea, Javier ^c   Lõpez, Manuela G ^c   Tasca, Carla I ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSIDADE DO CONTESTADO   (Brazil)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

adenosine receptors; glutamate uptake; guanosine; hippocampal slices; mitogen activated protein kinases signaling; oxygen glucose deprivation and reoxygenation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 MORPHOLINO 8 PHENYLCHROMONE; 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE RECEPTOR; CHARYBDOTOXIN; GLUCOSE; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; OXYGEN; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; TRITIUM; BK PROTEIN, RAT; DIAGNOSTIC AGENT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; NERVE PROTEIN; NEUROPROTECTIVE AGENT; NOS2 PROTEIN, RAT;

AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GLUCOSE DEPRIVATION; HIPPOCAMPUS; INFLAMMATION; MALE; MEDICAL PROCEDURES; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; OXYGEN DEPRIVATION; PRIORITY JOURNAL; RAT; REOXYGENATION; ADENOSINE RECEPTORS; ANIMAL; BRAIN HYPOXIA; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; ENCEPHALITIS; GLUTAMATE UPTAKE; HIPPOCAMPAL SLICES; IMMUNOLOGY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOGEN-ACTIVATED PROTEIN KINASES SIGNALING; ORGAN CULTURE TECHNIQUE; OXYGEN/GLUCOSE DEPRIVATION AND REOXYGENATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; WISTAR RAT;

ADENOSINE RECEPTORS; GLUTAMATE UPTAKE; GUANOSINE; HIPPOCAMPAL SLICES; MITOGEN-ACTIVATED PROTEIN KINASES SIGNALING; OXYGEN/GLUCOSE DEPRIVATION AND REOXYGENATION;

ANIMALS; CELL SURVIVAL; ENCEPHALITIS; GLUCOSE; GLUTAMIC ACID; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANOSINE; HIPPOCAMPUS; HYPOXIA, BRAIN; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; ORGAN CULTURE TECHNIQUES; OXIDATIVE STRESS; OXYGEN; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTOR, ADENOSINE A1; TRITIUM;

EID: 84885960224     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12324     Document Type: Article

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