Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 42, 2013, Pages 16856-16861

  Köpper, Frederik ^a   Bierwirth, Cathrin ^a   Schön, Margarete ^a   Kunze, Meike ^a   Elvers, Ingegerd ^b,g   Kranz, Dominique ^c,h   Saini, Priyanka ^a   Menon, Manoj B ^d   Walter, David ^e   Sørensen, Claus Storgaard ^e   Gaestel, Matthias ^d   Helleday, Thomas ^f   Schön, Michael P ^a   Dobbelstein, Matthias ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f KAROLINSKA INSTITUTE   (Sweden)

^g UPPSALA UNIVERSITY   (Sweden)

^h GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; DNA POLYMERASE; GEMCITABINE; HISTONE H2AX; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NUTLIN 3; PROTEIN P53; RIBONUCLEOTIDE REDUCTASE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA RESPONSIVE ELEMENT; DOWN REGULATION; ENZYME ACTIVITY; G2 PHASE CELL CYCLE CHECKPOINT; GENE TARGETING; HUMAN; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; PROTEINASE INHIBITION; RADIATION INDUCED NEOPLASM; REACTION TIME; S PHASE CELL CYCLE CHECKPOINT; SCREENING; ULTRAVIOLET IRRADIATION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE, TUMOR; DEOXYCYTIDINE; DNA DAMAGE; DNA REPLICATION; DNA, SINGLE-STRANDED; G2 PHASE CELL CYCLE CHECKPOINTS; GENE KNOCKDOWN TECHNIQUES; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; ULTRAVIOLET RAYS;

EID: 84885720011     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1304355110     Document Type: Article

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