Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues

Journal of Medicinal Chemistry

Volumn 56, Issue 19, 2013, Pages 7691-7705

  Zimmermann, Louis ^a   Bussière, Antoine ^a   Ouberai, Myriam ^b   Baussanne, Isabelle ^a   Jolivalt, Claude ^c   Mingeot Leclercq, Marie Paule ^b   Décout, Jean Luc ^a  

^a Laboratoire de Pharmacochimie   (France)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c PSL RESEARCH UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3' BROMOPROPYL)NAPHTHALENE; 2 (4' BROMOBUTYL)NAPHTHALENE; 2 (6' BROMOHEXYL)NAPHTHALENE; 3' MONO O OCTADECYL NEAMINE; 3',4',6 TRI O 1'' NAPHTHYLMETHYLENE NEAMINE; 3',4',6 TRI O 1'' NAPHTHYLMETHYLENE PAROMAMINE; 3',4',6 TRI O [3'' (2'''' NAPHTHYL)PROPYL] NEAMINE; 3',4',6 TRI O [4'' (2'''' NAPHTHYL)BUTYL] NEAMINE; 3',4',6 TRI O BUTYL NEAMINE; 3',6 DI O 1'' NAPHTHYLMETHYLENE NEAMINE; 3',6 DI O 1'' NAPHTHYLMETHYLENE PAROMAMINE; 3',6 DI O [3'' (2'''' NAPHTHYL)PROPYL] NEAMINE; 3',6 DI O BUTYL NEAMINE; 3',6 DI O NONYL NEAMINE; 3',6 DI O OCTODECYLL NEAMINE; 3',6' DI O [4'' (2'''' NAPHTHYL)BUTYL] NEAMINE; 3',6' DI O [6'' (2'''' NAPHTHYL)HEXYL] NEAMINE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; FRAMYCETIN; NEAMINE; PAROMAMINE; PAROMOMYCIN; UNCLASSIFIED DRUG;

ACINETOBACTER LWOFFII; ANTIBACTERIAL ACTIVITY; ARTICLE; CITROBACTER; DRUG SYNTHESIS; ENTEROBACTER AEROGENES; ESCHERICHIA COLI; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PSEUDOMONAS AERUGINOSA; VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; FRAMYCETIN; GRAM-NEGATIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; NAPHTHALENES; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84885611956     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401148j     Document Type: Article

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