Antibacterial activities of short designer peptides: A link between propensity for nanostructuring and capacity for membrane destabilization

Biomacromolecules

Volumn 11, Issue 2, 2010, Pages 402-411

  Chen, Cuixia ^a   Pan, Fang ^b   Zhang, Shengzhong ^a   Hu, Jing ^a   Cao, Meiwen ^a   Wang, Jing ^a   Xu, Hai ^a   Zhao, Xiubo ^b   Lu, Jian R ^b  

^a CHINA UNIVERSITY OF PETROLEUM   (China)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPHILICS; ANTI-BACTERIAL ACTIVITY; FLUORESCENCE IMAGING; HIGH SELECTIVITY; INCUBATION TIME; MEMBRANE BILAYERS; MEMBRANE DESTABILIZATION; MEMBRANE PENETRATION; MEMBRANE PERMEATION; MODEL MEMBRANES; NANO-STRUCTURING; NANOAGGREGATION; POSITIVE CORRELATIONS; SIZE AND SHAPE; STRONG CORRELATION; STRUCTURAL DISTURBANCES;

BACTERIOLOGY; FLEXIBLE STRUCTURES; HYDROPHOBICITY; NANORODS; PEPTIDES; SURFACE ACTIVE AGENTS;

MEMBRANE STRUCTURES;

ALANINE; ALANYLALANYLALANYLALANYLALANYLALANYLALANYLALANYLALANYLLYSINE; ALANYLALANYLALANYLALANYLALANYLALANYLLYSINE; ALANYLALANYLALANYLLYSINE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; BACTERICIDAL ACTIVITY; BILAYER MEMBRANE; BINDING AFFINITY; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG PENETRATION; DRUG SELECTIVITY; DRUG SYNTHESIS; FLUORESCENCE; HUMAN; HUMAN CELL; HYDROPHOBICITY; INCUBATION TIME; NONHUMAN; PARTICLE SIZE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SCANNING ELECTRON MICROSCOPY; STEADY STATE;

ANTI-BACTERIAL AGENTS; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; HUMANS; NANOSTRUCTURES; PEPTIDES; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS);

EID: 76249110195     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm901130u     Document Type: Article

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