-
1
-
-
84860669151
-
Targeting MDR in breast and lung cancer: Discriminating its potential importance from the failure of drug resistance reversal studies
-
Amiri-Kordestani L, Basseville A, Kurdziel K, Fojo AT, Bates SE, (2012). Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies. Drug Resist Updat 15: 50-61.
-
(2012)
Drug Resist Updat
, vol.15
, pp. 50-61
-
-
Amiri-Kordestani, L.1
Basseville, A.2
Kurdziel, K.3
Fojo, A.T.4
Bates, S.E.5
-
2
-
-
3543148259
-
Subcellular localization of the ABCG2 transporter in normal and malignant human gallbladder epithelium
-
Aust S, Obrist P, Jaeger W, Klimpfinger M, Tucek G, Wrba F, et al. (2004). Subcellular localization of the ABCG2 transporter in normal and malignant human gallbladder epithelium. Lab Invest 84: 1024-1036.
-
(2004)
Lab Invest
, vol.84
, pp. 1024-1036
-
-
Aust, S.1
Obrist, P.2
Jaeger, W.3
Klimpfinger, M.4
Tucek, G.5
Wrba, F.6
-
3
-
-
42049103473
-
Pleiotropic effects of telmisartan: Still more to come?
-
Benndorf RA, Boger RH, (2008). Pleiotropic effects of telmisartan: still more to come? J Hypertens 26: 854-856.
-
(2008)
J Hypertens
, vol.26
, pp. 854-856
-
-
Benndorf, R.A.1
Boger, R.H.2
-
4
-
-
1542547460
-
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity
-
Benson SC, Pershadsingh H, Ho C, Chittiboyina A, Desai P, Pravenec M, et al. (2004). Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension 43: 993-1002.
-
(2004)
Hypertension
, vol.43
, pp. 993-1002
-
-
Benson, S.C.1
Pershadsingh, H.2
Ho, C.3
Chittiboyina, A.4
Desai, P.5
Pravenec, M.6
-
5
-
-
60849117508
-
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, et al. (2009). PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4: 226-235.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
-
6
-
-
79960453436
-
Bid as a potential target of apoptotic effects exerted by low doses of PPARγ and RXR ligands in breast cancer cells
-
Bonofiglio D, Cione E, Vizza D, Perri M, Pingitore A, Qi H, et al. (2011). Bid as a potential target of apoptotic effects exerted by low doses of PPARγ and RXR ligands in breast cancer cells. Cell Cycle 10: 2344-2354.
-
(2011)
Cell Cycle
, vol.10
, pp. 2344-2354
-
-
Bonofiglio, D.1
Cione, E.2
Vizza, D.3
Perri, M.4
Pingitore, A.5
Qi, H.6
-
7
-
-
0036163796
-
ABC transporters as phenotypic markers and functional regulators of stem cells
-
Bunting KD, (2002). ABC transporters as phenotypic markers and functional regulators of stem cells. Stem Cells 20: 11-20.
-
(2002)
Stem Cells
, vol.20
, pp. 11-20
-
-
Bunting, K.D.1
-
8
-
-
80052088125
-
Identification of a novel, tissue-specific ABCG2 promoter expressed in pediatric acute megakaryoblastic leukemia
-
Campbell PK, Zong Y, Yang S, Zhou S, Rubnitz JE, Sorrentino BP, (2011). Identification of a novel, tissue-specific ABCG2 promoter expressed in pediatric acute megakaryoblastic leukemia. Leuk Res 35: 1321-1329.
-
(2011)
Leuk Res
, vol.35
, pp. 1321-1329
-
-
Campbell, P.K.1
Zong, Y.2
Yang, S.3
Zhou, S.4
Rubnitz, J.E.5
Sorrentino, B.P.6
-
9
-
-
0037352170
-
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
-
Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, et al. (2003). Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 17: 590-603.
-
(2003)
Leukemia
, vol.17
, pp. 590-603
-
-
Chang, F.1
Lee, J.T.2
Navolanic, P.M.3
Steelman, L.S.4
Shelton, J.G.5
Blalock, W.L.6
-
10
-
-
84862736573
-
Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells
-
Cheng Z, Yang N, Liang W, Yan X, Li L, Pan L, (2012). Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells. Leuk Lymphoma 53: 1383-1389.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 1383-1389
-
-
Cheng, Z.1
Yang, N.2
Liang, W.3
Yan, X.4
Li, L.5
Pan, L.6
-
11
-
-
0033911580
-
Absorption, disposition, and metabolism of rosiglitazone, a potent thiazolidinedione insulin sensitizer, in humans
-
Cox PJ, Ryan DA, Hollis FJ, Harris AM, Miller AK, Vousden M, et al. (2000). Absorption, disposition, and metabolism of rosiglitazone, a potent thiazolidinedione insulin sensitizer, in humans. Drug Metab Dispos 28: 772-780.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 772-780
-
-
Cox, P.J.1
Ryan, D.A.2
Hollis, F.J.3
Harris, A.M.4
Miller, A.K.5
Vousden, M.6
-
12
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
Elstner E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, et al. (1998). Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci U S A 95: 8806-8811.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
Williamson, E.A.4
Park, D.5
Asou, H.6
-
13
-
-
0042316755
-
PTEN: One gene, many syndromes
-
Eng C, (2003). PTEN: one gene, many syndromes. Hum Mutat 22: 183-198.
-
(2003)
Hum Mutat
, vol.22
, pp. 183-198
-
-
Eng, C.1
-
14
-
-
84859215796
-
Systemic elevation of PTEN induces a tumor-suppressive metabolic state
-
Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, et al. (2012). Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell 149: 49-62.
-
(2012)
Cell
, vol.149
, pp. 49-62
-
-
Garcia-Cao, I.1
Song, M.S.2
Hobbs, R.M.3
Laurent, G.4
Giorgi, C.5
De Boer, V.C.6
-
15
-
-
84859104590
-
Inhibition of the PI3K-Akt signaling pathway disrupts ABCG2-rich extracellular vesicles and overcomes multidrug resistance in breast cancer cells
-
Goler-Baron V, Sladkevich I, Assaraf YG, (2012). Inhibition of the PI3K-Akt signaling pathway disrupts ABCG2-rich extracellular vesicles and overcomes multidrug resistance in breast cancer cells. Biochem Pharmacol 83: 1340-1348.
-
(2012)
Biochem Pharmacol
, vol.83
, pp. 1340-1348
-
-
Goler-Baron, V.1
Sladkevich, I.2
Assaraf, Y.G.3
-
16
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
Gottesman MM, Fojo T, Bates SE, (2002). Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2: 48-58.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
17
-
-
84857184141
-
Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (review)
-
Hafsi S, Pezzino FM, Candido S, Ligresti G, Spandidos DA, Soua Z, et al. (2012). Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (review). Int J Oncol 40: 639-644.
-
(2012)
Int J Oncol
, vol.40
, pp. 639-644
-
-
Hafsi, S.1
Pezzino, F.M.2
Candido, S.3
Ligresti, G.4
Spandidos, D.A.5
Soua, Z.6
-
18
-
-
84859850547
-
PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter
-
Hegedus C, Truta-Feles K, Antalffy G, Brozik A, Kasza I, Nemet K, et al. (2012). PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter. Biochem Biophys Res Commun 420: 869-874.
-
(2012)
Biochem Biophys Res Commun
, vol.420
, pp. 869-874
-
-
Hegedus, C.1
Truta-Feles, K.2
Antalffy, G.3
Brozik, A.4
Kasza, I.5
Nemet, K.6
-
19
-
-
57349094741
-
Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation of Akt signaling
-
Hu H, Li H, Li J, Zhu Z, Yin S, Hao X, et al. (2008). Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation of Akt signaling. Carcinogenesis 29: 2289-2297.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2289-2297
-
-
Hu, H.1
Li, H.2
Li, J.3
Zhu, Z.4
Yin, S.5
Hao, X.6
-
20
-
-
84860752480
-
The PI3K/Akt inhibitor LY294002 reverses BCRP-mediated drug resistance without affecting BCRP translocation
-
Imai Y, Yoshimori M, Fukuda K, Yamagishi H, Ueda Y, (2012). The PI3K/Akt inhibitor LY294002 reverses BCRP-mediated drug resistance without affecting BCRP translocation. Oncol Rep 27: 1703-1709.
-
(2012)
Oncol Rep
, vol.27
, pp. 1703-1709
-
-
Imai, Y.1
Yoshimori, M.2
Fukuda, K.3
Yamagishi, H.4
Ueda, Y.5
-
21
-
-
33644893387
-
Effect of rifampicin on the pharmacokinetics of pioglitazone
-
Jaakkola T, Backman JT, Neuvonen M, Laitila J, Neuvonen PJ, (2005). Effect of rifampicin on the pharmacokinetics of pioglitazone. Br J Clin Pharmacol 61: 70-78.
-
(2005)
Br J Clin Pharmacol
, vol.61
, pp. 70-78
-
-
Jaakkola, T.1
Backman, J.T.2
Neuvonen, M.3
Laitila, J.4
Neuvonen, P.J.5
-
22
-
-
77449143886
-
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes
-
Kamiyama E, Nakai D, Mikkaichi T, Okudaira N, Okazaki O, (2010). Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes. Life Sci 86: 52-58.
-
(2010)
Life Sci
, vol.86
, pp. 52-58
-
-
Kamiyama, E.1
Nakai, D.2
Mikkaichi, T.3
Okudaira, N.4
Okazaki, O.5
-
23
-
-
80053436675
-
The ABCG family of membrane-associated transporters: You don't have to be big to be mighty
-
Kerr ID, Haider AJ, Gelissen IC, (2011). The ABCG family of membrane-associated transporters: you don't have to be big to be mighty. Br J Pharmacol 164: 1767-1779.
-
(2011)
Br J Pharmacol
, vol.164
, pp. 1767-1779
-
-
Kerr, I.D.1
Haider, A.J.2
Gelissen, I.C.3
-
24
-
-
0035497756
-
PPARgamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in ras-transformed rat intestinal epithelial cells
-
Kitamura S, Miyazaki Y, Hiraoka S, Nagasawa Y, Toyota M, Takakura R, et al. (2001). PPARgamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in ras-transformed rat intestinal epithelial cells. Int J Cancer 94: 335-342.
-
(2001)
Int J Cancer
, vol.94
, pp. 335-342
-
-
Kitamura, S.1
Miyazaki, Y.2
Hiraoka, S.3
Nagasawa, Y.4
Toyota, M.5
Takakura, R.6
-
25
-
-
0037235020
-
Peroxisome proliferator-activated receptor gamma and cancers
-
Koeffler HP, (2003). Peroxisome proliferator-activated receptor gamma and cancers. Clin Cancer Res 9: 1-9.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1-9
-
-
Koeffler, H.P.1
-
26
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate
-
Maehama T, Dixon JE, (1998). The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate. J Biol Chem 273: 13375-13378.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
27
-
-
84862964905
-
ABCG2/BCRP dysfunction as a major cause of gout
-
Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Suzuki H, et al. (2011). ABCG2/BCRP dysfunction as a major cause of gout. Nucleosides Nucleotides Nucleic Acids 30: 1117-1128.
-
(2011)
Nucleosides Nucleotides Nucleic Acids
, vol.30
, pp. 1117-1128
-
-
Matsuo, H.1
Takada, T.2
Ichida, K.3
Nakamura, T.4
Nakayama, A.5
Suzuki, H.6
-
28
-
-
0141866694
-
Akt signaling regulates side population cell phenotype via Bcrp translocation
-
Mogi M, Yang J, Lambert JF, Colvin GA, Shiojima I, Skurk C, et al. (2003). Akt signaling regulates side population cell phenotype via Bcrp translocation. J Biol Chem 278: 39068-39075.
-
(2003)
J Biol Chem
, vol.278
, pp. 39068-39075
-
-
Mogi, M.1
Yang, J.2
Lambert, J.F.3
Colvin, G.A.4
Shiojima, I.5
Skurk, C.6
-
29
-
-
79960720457
-
Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine
-
Natarajan K, Xie Y, Nakanishi T, Beck WT, Bauer KS, Ross DD, (2011). Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine. Biochim Biophys Acta 1809: 295-305.
-
(2011)
Biochim Biophys Acta
, vol.1809
, pp. 295-305
-
-
Natarajan, K.1
Xie, Y.2
Nakanishi, T.3
Beck, W.T.4
Bauer, K.S.5
Ross, D.D.6
-
30
-
-
20044365778
-
Function-dependent conformational changes of the ABCG2 multidrug transport modify its interaction with a monoclonal antibody on the cell surface
-
Ozvegy-Laczka C, Varady G, Koblos G, Ujhelly O, Cervenak J, Schuetz JD, et al. (2005). Function-dependent conformational changes of the ABCG2 multidrug transport modify its interaction with a monoclonal antibody on the cell surface. J Biol Chem 280: 4219-4227.
-
(2005)
J Biol Chem
, vol.280
, pp. 4219-4227
-
-
Ozvegy-Laczka, C.1
Varady, G.2
Koblos, G.3
Ujhelly, O.4
Cervenak, J.5
Schuetz, J.D.6
-
31
-
-
0035873953
-
Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN
-
Patel L, Pass I, Coxon P, Downes CP, Smith SA, Macphee CH, (2001). Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. Curr Biol 11: 764-768.
-
(2001)
Curr Biol
, vol.11
, pp. 764-768
-
-
Patel, L.1
Pass, I.2
Coxon, P.3
Downes, C.P.4
Smith, S.A.5
Macphee, C.H.6
-
32
-
-
3242658028
-
Mutational analysis of ABCG2: Role of the GXXXG motif
-
Polgar O, Robey RW, Morisaki K, Dean M, Michejda C, Sauna ZE, et al. (2004). Mutational analysis of ABCG2: role of the GXXXG motif. Biochemistry 43: 9448-9456.
-
(2004)
Biochemistry
, vol.43
, pp. 9448-9456
-
-
Polgar, O.1
Robey, R.W.2
Morisaki, K.3
Dean, M.4
Michejda, C.5
Sauna, Z.E.6
-
33
-
-
77949344456
-
Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in TM1 of ABCG2
-
Polgar O, Lerano C, Tamaki A, Stanley B, Ward Y, Xia D, et al. (2010). Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in TM1 of ABCG2. Biochemistry 49: 2235-2245.
-
(2010)
Biochemistry
, vol.49
, pp. 2235-2245
-
-
Polgar, O.1
Lerano, C.2
Tamaki, A.3
Stanley, B.4
Ward, Y.5
Xia, D.6
-
34
-
-
0035138482
-
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCRP/ABCP1), in flavopiridol-resistant human breast cancer cells
-
Robey RW, Medina-Perez WY, Nishiyama K, Lahusen T, Miyake K, Litman T, et al. (2001). Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCRP/ABCP1), in flavopiridol-resistant human breast cancer cells. Clin Cancer Res 7: 145-152.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 145-152
-
-
Robey, R.W.1
Medina-Perez, W.Y.2
Nishiyama, K.3
Lahusen, T.4
Miyake, K.5
Litman, T.6
-
35
-
-
1242293677
-
Pheophorbide A is a specific probe for ABCG2 function and inhibition
-
Robey RW, Steadman K, Polgar O, Morisaki K, Blayney M, Mistry P, et al. (2004). Pheophorbide A is a specific probe for ABCG2 function and inhibition. Cancer Res 64: 1242-1246.
-
(2004)
Cancer Res
, vol.64
, pp. 1242-1246
-
-
Robey, R.W.1
Steadman, K.2
Polgar, O.3
Morisaki, K.4
Blayney, M.5
Mistry, P.6
-
36
-
-
0034234653
-
Expression of breast cancer resistance protein in blast cells from patients with acute leukemia
-
Ross DD, Karp JE, Chen TT, Doyle LA, (2000). Expression of breast cancer resistance protein in blast cells from patients with acute leukemia. Blood 96: 365-368.
-
(2000)
Blood
, vol.96
, pp. 365-368
-
-
Ross, D.D.1
Karp, J.E.2
Chen, T.T.3
Doyle, L.A.4
-
38
-
-
0001223675
-
Future perspectives for the development of P-glycoprotein modulators
-
Sandor V, Fojo T, Bates SE, (1998). Future perspectives for the development of P-glycoprotein modulators. Drug Resist Updat 1: 190-200.
-
(1998)
Drug Resist Updat
, vol.1
, pp. 190-200
-
-
Sandor, V.1
Fojo, T.2
Bates, S.E.3
-
39
-
-
0038101440
-
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites
-
Schmidt B, Schieffer B, (2003). Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites. J Med Chem 46: 2261-2270.
-
(2003)
J Med Chem
, vol.46
, pp. 2261-2270
-
-
Schmidt, B.1
Schieffer, B.2
-
40
-
-
2442451618
-
Angiotensin type i receptor blockers induce peroxisome proliferator-activated receptor-γ activity
-
Schupp M, Janke J, Clasen R, Unger T, Kintscher U, (2004). Angiotensin type I receptor blockers induce peroxisome proliferator-activated receptor-γ activity. Circulation 109: 2054-2057.
-
(2004)
Circulation
, vol.109
, pp. 2054-2057
-
-
Schupp, M.1
Janke, J.2
Clasen, R.3
Unger, T.4
Kintscher, U.5
-
41
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P, Stornet R, Scudiero D, Monks A, McMahon J, Vistica D, et al. (1990). New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107-1112.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Stornet, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
-
42
-
-
0033751014
-
Dose response and safety of telmisartan in patients with mild to moderate hypertension
-
Smith DHG, Matzek KM, Kempthorne-Rawson J, (2000). Dose response and safety of telmisartan in patients with mild to moderate hypertension. J Clin Pharmacol 40: 1380-1390.
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 1380-1390
-
-
Smith, D.H.G.1
Matzek, K.M.2
Kempthorne-Rawson, J.3
-
43
-
-
23644456172
-
Therapeutic roles of peroxisome proliferator-activated receptor agonists
-
Staels B, Fruchart JC, (2005). Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 54: 2460-2470.
-
(2005)
Diabetes
, vol.54
, pp. 2460-2470
-
-
Staels, B.1
Fruchart, J.C.2
-
44
-
-
0032475861
-
Negative regulation of PKB/AKT-dependent cell survival by tumor suppressor PTEN
-
Stambolic V, Suzuki A, de la Pompa JL, Brothers GM, Mirtsos C, Sasaki T, et al. (1998). Negative regulation of PKB/AKT-dependent cell survival by tumor suppressor PTEN. Cell 95: 29-39.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
-
45
-
-
0033748479
-
The effect of telmisartan on the steady-state pharmacokinetics of digoxin in healthy male volunteers
-
Stangier J, Su CA, Hendriks MG, van Lier JJ, Sollie FA, Oosterhuis B, et al. (2000). The effect of telmisartan on the steady-state pharmacokinetics of digoxin in healthy male volunteers. J Clin Pharmacol 40: 1373-1379.
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 1373-1379
-
-
Stangier, J.1
Su, C.A.2
Hendriks, M.G.3
Van Lier, J.J.4
Sollie, F.A.5
Oosterhuis, B.6
-
46
-
-
33747640562
-
Peroxisome proliferators-activated receptor γ-regulated ABCG2 expression confers cytoprotection to human dendritic cells
-
Szatmari I, Vamosi G, Brazda P, Balint BL, Benkp S, Szeles L, et al. (2006). Peroxisome proliferators-activated receptor γ-regulated ABCG2 expression confers cytoprotection to human dendritic cells. J Biol Chem 281: 23812-23823.
-
(2006)
J Biol Chem
, vol.281
, pp. 23812-23823
-
-
Szatmari, I.1
Vamosi, G.2
Brazda, P.3
Balint, B.L.4
Benkp, S.5
Szeles, L.6
-
47
-
-
22344435180
-
Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells
-
Takada T, Suzuki H, Gotoh Y, Sugiuama Y, (2005). Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells. Drug Metab Dispos 33: 905-909.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 905-909
-
-
Takada, T.1
Suzuki, H.2
Gotoh, Y.3
Sugiuama, Y.4
-
48
-
-
84856282091
-
The controversial role of ABC transporters in clinical oncology
-
Tamaki A, Ierano C, Szakacs G, Robey RW, Bates SE, (2011). The controversial role of ABC transporters in clinical oncology. Essays Biochem 50: 209-232.
-
(2011)
Essays Biochem
, vol.50
, pp. 209-232
-
-
Tamaki, A.1
Ierano, C.2
Szakacs, G.3
Robey, R.W.4
Bates, S.E.5
-
49
-
-
33646434260
-
Increased PTEN expression due to transcriptional activation of PPARgamma by lovastatin and rosiglitazone
-
Teresi RE, Shaiu CW, Chen CS, Chatterjee VK, Waite KA, Eng C, (2006). Increased PTEN expression due to transcriptional activation of PPARgamma by lovastatin and rosiglitazone. Int J Cancer 118: 2390-2398.
-
(2006)
Int J Cancer
, vol.118
, pp. 2390-2398
-
-
Teresi, R.E.1
Shaiu, C.W.2
Chen, C.S.3
Chatterjee, V.K.4
Waite, K.A.5
Eng, C.6
-
50
-
-
40749118502
-
Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells
-
To KK, Polgar O, Huff LM, Morisaki K, Bates SE, (2008). Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells. Mol Cancer Res 6: 151-164.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 151-164
-
-
To, K.K.1
Polgar, O.2
Huff, L.M.3
Morisaki, K.4
Bates, S.E.5
-
51
-
-
84859916423
-
Constitutive AhR activation leads to concomitant ABCG2-mediated multidrug resistance in cisplatin-resistant esophageal carcinoma cells
-
To KK, Yu L, Liu S, Fu J, Cho CH, (2012). Constitutive AhR activation leads to concomitant ABCG2-mediated multidrug resistance in cisplatin-resistant esophageal carcinoma cells. Mol Carcinog 51: 449-464.
-
(2012)
Mol Carcinog
, vol.51
, pp. 449-464
-
-
To, K.K.1
Yu, L.2
Liu, S.3
Fu, J.4
Cho, C.H.5
-
52
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL, (2002). The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2: 489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
53
-
-
77951031222
-
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters
-
Weiss J, Sauer A, Divac N, Herzog M, Schwedhelm E, Boger RH, et al. (2010). Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters. Biopharm Drug Dispos 31: 150-161.
-
(2010)
Biopharm Drug Dispos
, vol.31
, pp. 150-161
-
-
Weiss, J.1
Sauer, A.2
Divac, N.3
Herzog, M.4
Schwedhelm, E.5
Boger, R.H.6
-
54
-
-
51449095342
-
Targeting the PI3K-AKT-mTOR pathway: Progress, pitfalls, and promises
-
Yap TA, Garrett MD, Walton MI, Raynaud F, de Bono JS, Workman P, (2008). Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises. Curr Opin Pharmacol 8: 393-412.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 393-412
-
-
Yap, T.A.1
Garrett, M.D.2
Walton, M.I.3
Raynaud, F.4
De Bono, J.S.5
Workman, P.6
-
55
-
-
3242890471
-
SiRNA Selection Server: An automated siRNA oligonucleotide prediction server
-
Yuan B, Latek R, Hossbach M, Tuschi T, Lewitter F, (2004). siRNA Selection Server: an automated siRNA oligonucleotide prediction server. Nucleic Acids Res 32: W130-W134.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Yuan, B.1
Latek, R.2
Hossbach, M.3
Tuschi, T.4
Lewitter, F.5
-
56
-
-
0029775642
-
Insulin- and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ
-
Zhang B, Berger J, Zhou G, Elbrecht A, Biswas S, White-Carrington S, et al. (1996). Insulin- and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ. J Biol Chem 271: 31771-31774.
-
(1996)
J Biol Chem
, vol.271
, pp. 31771-31774
-
-
Zhang, B.1
Berger, J.2
Zhou, G.3
Elbrecht, A.4
Biswas, S.5
White-Carrington, S.6
-
57
-
-
77954709180
-
Design and synthesis of permethyl ningalin B analogues: Potent multidrug resistance (MDR) reversal agents of cancer cells
-
Zhang PY, Wong IL, Yan CS, Zhang XY, Jiang T, Chow LM, et al. (2010). Design and synthesis of permethyl ningalin B analogues: potent multidrug resistance (MDR) reversal agents of cancer cells. J Med Chem 53: 5108-5120.
-
(2010)
J Med Chem
, vol.53
, pp. 5108-5120
-
-
Zhang, P.Y.1
Wong, I.L.2
Yan, C.S.3
Zhang, X.Y.4
Jiang, T.5
Chow, L.M.6
-
58
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side population phenotype
-
Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, et al. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side population phenotype. Nat Med 7: 1028-1034.
-
(2001)
Nat Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
-
59
-
-
33749582524
-
Expression of mouse Abcg2 mRNA during hematopoiesis is regulated by alternative use of multiple leader exons and promoters
-
Zong Y, Zhou S, Fatima S, Sorrentino BP, (2006). Expression of mouse Abcg2 mRNA during hematopoiesis is regulated by alternative use of multiple leader exons and promoters. J Biol Chem 281: 29625-29632.
-
(2006)
J Biol Chem
, vol.281
, pp. 29625-29632
-
-
Zong, Y.1
Zhou, S.2
Fatima, S.3
Sorrentino, B.P.4
|