Design and syntheses of permethyl ningalin B analogues: Potent multidrug resistance (MDR) reversal agents of cancer cells

Journal of Medicinal Chemistry

Volumn 53, Issue 14, 2010, Pages 5108-5120

  Zhang, Pu Yong ^a   Wong, Iris L K ^b,c   Yan, Clare S W ^b,c   Zhang, Xiao Yu ^a   Jiang, Tao ^a   Chow, Larry M C ^b,c   Wan, Sheng Biao ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^c State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3,4,5 TRIMETHOXYBENZYL) 3,4 BIS(3,4 DIMETHOXYPHENYL) 1H PYRROLE 2,5 DIONE; 1 [2 (4 METHOXYPHENYL) 2 OXOETHYL] 3,4 BIS(3,4 DIMETHOXYPHENYL) 1H PYRROLE 2,5 DIONE; DOXORUBICIN; NINGALIN B; NINGALIN B DERIVATIVE; PACLITAXEL; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG; VINCRISTINE;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; MULTIDRUG RESISTANCE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOXORUBICIN; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; P-GLYCOPROTEIN; PACLITAXEL; PYRROLES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; VINCRISTINE;

EID: 77954709180     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100035c     Document Type: Article

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