Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2

Biochemistry

Volumn 49, Issue 10, 2010, Pages 2235-2245

  Polgar, Orsolya ^a   Ierano, Caterina ^a   Tamaki, Akina ^a   Stanley, Bradford ^b   Ward, Yvona ^a   Xia, Di ^a   Tarasova, Nadya ^c   Robey, Robert W ^a   Batest, Susan E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b YALE UNIVERSITY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP-BINDING CASSETTE; BAFILOMYCIN; DIMER INTERFACE; DRUG DISTRIBUTION; ENDOPLASMIC RETICULUM; HOMODIMERIZATION; HOMOLOGY MODELING; IMMUNOBLOT ANALYSIS; IMMUNOSTAINING; MUTATIONAL ANALYSIS; NORMAL TISSUE; SIGNIFICANT IMPACTS; SINGLE MUTATION; TRANSMEMBRANE SEGMENTS; WILD TYPES;

AMINO ACIDS; NORMAL DISTRIBUTION; PHOSPHATASES;

DIMERIZATION;

ARGININE; BREAST CANCER RESISTANCE PROTEIN; GLYCINE; LEUCINE; THREONINE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIMERIZATION; DISULFIDE BOND; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; GLYCOSYLATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIAL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CELL MEMBRANE; CROSS-LINKING REAGENTS; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION REGULATION; GLYCOSIDE HYDROLASES; HUMANS; LEUPEPTINS; MACROLIDES; MITOXANTRONE; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM PROTEINS; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN TRANSPORT; THREONINE;

EID: 77949344456     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902085q     Document Type: Article

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