-
1
-
-
0030602796
-
The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal
-
Alcedo, J., Ayzenzon, M., Von Ohlen, T., Noll, M. and Hooper, J. E. (1996). The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal. Cell 86, 221-232.
-
(1996)
Cell
, vol.86
, pp. 221-232
-
-
Alcedo, J.1
Ayzenzon, M.2
Von Ohlen, T.3
Noll, M.4
Hooper, J.E.5
-
2
-
-
12344305145
-
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
-
Apionishev, S., Katanayeva, N. M., Marks, S. A., Kalderon, D., and Tomlinson, A. (2005). Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction. Nat. Cell Biol. 7, 86-92.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 86-92
-
-
Apionishev, S.1
Katanayeva, N.M.2
Marks, S.A.3
Kalderon, D.4
Tomlinson, A.5
-
3
-
-
77952546990
-
Evaluating Smoothened as a G-proteincoupled receptor for Hedgehog signalling
-
Ayers, K. L., and Thérond, P. P. (2010). Evaluating Smoothened as a G-proteincoupled receptor for Hedgehog signalling. Trends Cell Biol. 20, 287-298.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 287-298
-
-
Ayers, K.L.1
Thérond, P.P.2
-
4
-
-
31744436399
-
Fluorescence cross-correlation spectroscopy in living cells
-
Bacia, K., Kim, S. A., and Schwille, P. (2006). Fluorescence cross-correlation spectroscopy in living cells. Nat. Methods 3, 83-89.
-
(2006)
Nat. Methods
, vol.3
, pp. 83-89
-
-
Bacia, K.1
Kim, S.A.2
Schwille, P.3
-
5
-
-
33747332214
-
Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion
-
Bijlsma, M. F., Spek, C. A., Zivkovic, D., van de Water, S., Rezaee, F., and Peppelenbosch, M. P. (2006). Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. PLoS Biol. 4, e232.
-
(2006)
PLoS Biol.
, vol.4
-
-
Bijlsma, M.F.1
Spek, C.A.2
Zivkovic, D.3
van de Water, S.4
Rezaee, F.5
Peppelenbosch, M.P.6
-
6
-
-
0025979817
-
An extensive 39 cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila
-
Blackman, R. K., Sanicola, M., Raftery, L. A., Gillevet, T., and Gelbart, W. M. (1991). An extensive 39 cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila. Development 111, 657-666.
-
(1991)
Development
, vol.111
, pp. 657-666
-
-
Blackman, R.K.1
Sanicola, M.2
Raftery, L.A.3
Gillevet, T.4
Gelbart, W.M.5
-
7
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand, A. H., and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
8
-
-
84879414522
-
The mechanisms of Hedgehog signalling and its roles in development and disease
-
Briscoe, J., and Thérond, P. P. (2013). The mechanisms of Hedgehog signalling and its roles in development and disease. Nat. Rev. Mol. Cell Biol. 14, 418-431.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 418-431
-
-
Briscoe, J.1
Thérond, P.P.2
-
9
-
-
0029852209
-
Visualization of gene expression in living adult Drosophila
-
Calleja, M., Moreno, E., Pelaz, S., and Morata, G. (1996). Visualization of gene expression in living adult Drosophila. Science 274, 252-255.
-
(1996)
Science
, vol.274
, pp. 252-255
-
-
Calleja, M.1
Moreno, E.2
Pelaz, S.3
Morata, G.4
-
10
-
-
0028208698
-
Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless reception complex in Drosophila embryos
-
Capdevila, J., Pariente, F., Sampedro, J., Alonso, J. L., and Guerrero, I. (1994). Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless reception complex in Drosophila embryos. Development 120, 987-998.
-
(1994)
Development
, vol.120
, pp. 987-998
-
-
Capdevila, J.1
Pariente, F.2
Sampedro, J.3
Alonso, J.L.4
Guerrero, I.5
-
11
-
-
0023392945
-
High-efficiency transformation of mammalian cells by plasmid DNA
-
Chen, C., and Okayama, H. (1987). High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2745-2752
-
-
Chen, C.1
Okayama, H.2
-
12
-
-
0030297553
-
Dual roles for patched in sequestering and transducing Hedgehog
-
Chen, Y., and Struhl, G. (1996). Dual roles for patched in sequestering and transducing Hedgehog. Cell 87, 553-563.
-
(1996)
Cell
, vol.87
, pp. 553-563
-
-
Chen, Y.1
Struhl, G.2
-
13
-
-
79551596885
-
The transcriptional diversity of 25 Drosophila cell lines
-
Cherbas, L., Willingham, A., Zhang, D., Yang, L., Zou, Y., Eads, B. D., Carlson, J. W., Landolin, J. M., Kapranov, P., Dumais, J. et al. (2011). The transcriptional diversity of 25 Drosophila cell lines. Genome Res. 21, 301-314.
-
(2011)
Genome Res.
, vol.21
, pp. 301-314
-
-
Cherbas, L.1
Willingham, A.2
Zhang, D.3
Yang, L.4
Zou, Y.5
Eads, B.D.6
Carlson, J.W.7
Landolin, J.M.8
Kapranov, P.9
Dumais, J.10
-
14
-
-
0034682719
-
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
-
Denef, N., Neubüser, D., Perez, L., and Cohen, S. M. (2000). Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened. Cell 102, 521-531.
-
(2000)
Cell
, vol.102
, pp. 521-531
-
-
Denef, N.1
Neubüser, D.2
Perez, L.3
Cohen, S.M.4
-
15
-
-
38349043781
-
Collier transcription in a single Drosophila muscle lineage: the combinatorial control of muscle identity
-
Dubois, L., Enriquez, J., Daburon, V., Crozet, F., Lebreton, G., Crozatier, M., and Vincent, A. (2007). Collier transcription in a single Drosophila muscle lineage: the combinatorial control of muscle identity. Development 134, 4347-4355.
-
(2007)
Development
, vol.134
, pp. 4347-4355
-
-
Dubois, L.1
Enriquez, J.2
Daburon, V.3
Crozet, F.4
Lebreton, G.5
Crozatier, M.6
Vincent, A.7
-
16
-
-
84861225973
-
Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose-and positiondependent manner
-
Fan, J., Liu, Y., and Jia, J. (2012). Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose-and positiondependent manner. Dev. Biol. 366, 172-184.
-
(2012)
Dev. Biol.
, vol.366
, pp. 172-184
-
-
Fan, J.1
Liu, Y.2
Jia, J.3
-
17
-
-
0015847039
-
A new technique for the assay of infectivity of human adenovirus 5 DNA
-
Graham, F. L., and van der Eb, A. J. (1973). A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52, 456-467.
-
(1973)
Virology
, vol.52
, pp. 456-467
-
-
Graham, F.L.1
van der Eb, A.J.2
-
18
-
-
43849083731
-
Dark states in monomeric red fluorescent proteins studied by fluorescence correlation and single molecule spectroscopy
-
Hendrix, J., Flors, C., Dedecker, P., Hofkens, J., and Engelborghs, Y. (2008). Dark states in monomeric red fluorescent proteins studied by fluorescence correlation and single molecule spectroscopy. Biophys. J. 94, 4103-4113.
-
(2008)
Biophys. J.
, vol.94
, pp. 4103-4113
-
-
Hendrix, J.1
Flors, C.2
Dedecker, P.3
Hofkens, J.4
Engelborghs, Y.5
-
19
-
-
33845368513
-
COPASI -a COmplex PAthway SImulator
-
Hoops, S., Sahle, S., Gauges, R., Lee, C., Pahle, J., Simus, N., Singhal, M., Xu, L., Mendes, P., and Kummer, U. (2006). COPASI -a COmplex PAthway SImulator. Bioinformatics 22, 3067-3074.
-
(2006)
Bioinformatics
, vol.22
, pp. 3067-3074
-
-
Hoops, S.1
Sahle, S.2
Gauges, R.3
Lee, C.4
Pahle, J.5
Simus, N.6
Singhal, M.7
Xu, L.8
Mendes, P.9
Kummer, U.10
-
20
-
-
0025815911
-
Role of the Drosophila patched gene in positional signalling
-
Ingham, P. W., Taylor, A. M., and Nakano, Y. (1991). Role of the Drosophila patched gene in positional signalling. Nature 353, 184-187.
-
(1991)
Nature
, vol.353
, pp. 184-187
-
-
Ingham, P.W.1
Taylor, A.M.2
Nakano, Y.3
-
21
-
-
79956308325
-
Mechanisms and functions of Hedgehog signalling across the metazoa
-
Ingham, P. W., Nakano, Y., and Seger, C. (2011). Mechanisms and functions of Hedgehog signalling across the metazoa. Nat. Rev. Genet. 12, 393-406.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 393-406
-
-
Ingham, P.W.1
Nakano, Y.2
Seger, C.3
-
22
-
-
0242361620
-
Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail
-
Jia, J., Tong, C., and Jiang, J. (2003). Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail. Genes Dev. 17, 2709-2720.
-
(2003)
Genes Dev.
, vol.17
, pp. 2709-2720
-
-
Jia, J.1
Tong, C.2
Jiang, J.3
-
23
-
-
11144237279
-
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I
-
Jia, J., Tong, C., Wang, B., Luo, L., and Jiang, J. (2004). Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature 432, 1045-1050.
-
(2004)
Nature
, vol.432
, pp. 1045-1050
-
-
Jia, J.1
Tong, C.2
Wang, B.3
Luo, L.4
Jiang, J.5
-
24
-
-
62349102527
-
PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation
-
Jia, H., Liu, Y., Yan, W., and Jia, J. (2009). PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation. Development 136, 307-316.
-
(2009)
Development
, vol.136
, pp. 307-316
-
-
Jia, H.1
Liu, Y.2
Yan, W.3
Jia, J.4
-
25
-
-
78549236202
-
Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus
-
Jia, H., Liu, Y., Xia, R., Tong, C., Yue, T., Jiang, J., and Jia, J. (2010). Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus. J. Biol. Chem. 285, 37218-37226.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 37218-37226
-
-
Jia, H.1
Liu, Y.2
Xia, R.3
Tong, C.4
Yue, T.5
Jiang, J.6
Jia, J.7
-
26
-
-
57049089995
-
Hedgehog signaling in development and cancer
-
Jiang, J., and Hui, C. C. (2008). Hedgehog signaling in development and cancer. Dev. Cell 15, 801-812.
-
(2008)
Dev. Cell
, vol.15
, pp. 801-812
-
-
Jiang, J.1
Hui, C.C.2
-
27
-
-
0033636788
-
In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration
-
Johnson, R. L., Milenkovic, L., and Scott, M. P. (2000). In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration. Mol. Cell 6, 467-478.
-
(2000)
Mol. Cell
, vol.6
, pp. 467-478
-
-
Johnson, R.L.1
Milenkovic, L.2
Scott, M.P.3
-
28
-
-
71449084811
-
Patched regulates Smoothened trafficking using lipoprotein-derived lipids
-
Khaliullina, H., Panáková, D., Eugster, C., Riedel, F., Carvalho, M., and Eaton, S. (2009). Patched regulates Smoothened trafficking using lipoprotein-derived lipids. Development 136, 4111-4121.
-
(2009)
Development
, vol.136
, pp. 4111-4121
-
-
Khaliullina, H.1
Panáková, D.2
Eugster, C.3
Riedel, F.4
Carvalho, M.5
Eaton, S.6
-
29
-
-
84863012714
-
Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila
-
Li, S., Chen, Y., Shi, Q., Yue, T., Wang, B., and Jiang, J. (2012). Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila. PLoS Biol. 10, e1001239.
-
(2012)
PLoS Biol.
, vol.10
-
-
Li, S.1
Chen, Y.2
Shi, Q.3
Yue, T.4
Wang, B.5
Jiang, J.6
-
30
-
-
34547621412
-
Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation
-
Liu, Y., Cao, X., Jiang, J., and Jia, J. (2007). Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation. Genes Dev. 21, 1949-1963.
-
(2007)
Genes Dev.
, vol.21
, pp. 1949-1963
-
-
Liu, Y.1
Cao, X.2
Jiang, J.3
Jia, J.4
-
31
-
-
10744233219
-
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2
-
Lum, L., Zhang, C., Oh, S., Mann, R. K., von Kessler, D. P., Taipale, J., Weis-Garcia, F., Gong, R., Wang, B., and Beachy, P. A. (2003). Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2. Mol. Cell 12, 1261-1274.
-
(2003)
Mol. Cell
, vol.12
, pp. 1261-1274
-
-
Lum, L.1
Zhang, C.2
Oh, S.3
Mann, R.K.4
von Kessler, D.P.5
Taipale, J.6
Weis-Garcia, F.7
Gong, R.8
Wang, B.9
Beachy, P.A.10
-
32
-
-
33646892646
-
Dynasore, a cell-permeable inhibitor of dynamin
-
Macia, E., Ehrlich, M., Massol, R., Boucrot, E., Brunner, C., and Kirchhausen, T. (2006). Dynasore, a cell-permeable inhibitor of dynamin. Dev. Cell 10, 839-850.
-
(2006)
Dev. Cell
, vol.10
, pp. 839-850
-
-
Macia, E.1
Ehrlich, M.2
Massol, R.3
Boucrot, E.4
Brunner, C.5
Kirchhausen, T.6
-
33
-
-
51749122228
-
Dynamical modeling and multi-experiment fitting with PottersWheel
-
Maiwald, T., and Timmer, J. (2008). Dynamical modeling and multi-experiment fitting with PottersWheel. Bioinformatics 24, 2037-2043.
-
(2008)
Bioinformatics
, vol.24
, pp. 2037-2043
-
-
Maiwald, T.1
Timmer, J.2
-
34
-
-
0029948270
-
Biochemical evidence that patched is the Hedgehog receptor
-
Marigo, V., Davey, R. A., Zuo, Y., Cunningham, J. M., and Tabin, C. J. (1996). Biochemical evidence that patched is the Hedgehog receptor. Nature 384, 176-179.
-
(1996)
Nature
, vol.384
, pp. 176-179
-
-
Marigo, V.1
Davey, R.A.2
Zuo, Y.3
Cunningham, J.M.4
Tabin, C.J.5
-
35
-
-
0035901616
-
The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking
-
Martín, V., Carrillo, G., Torroja, C., and Guerrero, I. (2001). The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking. Curr. Biol. 11, 601-607.
-
(2001)
Curr. Biol.
, vol.11
, pp. 601-607
-
-
Martín, V.1
Carrillo, G.2
Torroja, C.3
Guerrero, I.4
-
36
-
-
79961177157
-
Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche
-
Michel, M., Raabe, I., Kupinski, A. P., Pérez-Palencia, R., and Bökel, C. (2011). Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche. Nat. Commun 2, 415.
-
(2011)
Nat. Commun
, vol.2
, pp. 415
-
-
Michel, M.1
Raabe, I.2
Kupinski, A.P.3
Pérez-Palencia, R.4
Bökel, C.5
-
37
-
-
84869110535
-
Hh signalling is essential for somatic stem cell maintenance in the Drosophila testis niche
-
Michel, M., Kupinski, A. P., Raabe, I., and Bökel, C. (2012). Hh signalling is essential for somatic stem cell maintenance in the Drosophila testis niche. Development 139, 2663-2669.
-
(2012)
Development
, vol.139
, pp. 2663-2669
-
-
Michel, M.1
Kupinski, A.P.2
Raabe, I.3
Bökel, C.4
-
38
-
-
0032759039
-
Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo
-
Moline, M. M., Southern, C., and Bejsovec, A. (1999). Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo. Development 126, 4375-4384.
-
(1999)
Development
, vol.126
, pp. 4375-4384
-
-
Moline, M.M.1
Southern, C.2
Bejsovec, A.3
-
39
-
-
79953754361
-
Role of the Drosophila non-visual β-arrestin kurtz in hedgehog signalling
-
Molnar, C., Ruiz-Gómez, A., Martín, M., Rojo-Berciano, S., Mayor, F., and de Celis, J. F. (2011). Role of the Drosophila non-visual β-arrestin kurtz in hedgehog signalling. PLoS Genet. 7, e1001335.
-
(2011)
PLoS Genet.
, vol.7
-
-
Molnar, C.1
Ruiz-Gómez, A.2
Martín, M.3
Rojo-Berciano, S.4
Mayor, F.5
de Celis, J.F.6
-
40
-
-
0029126148
-
The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways
-
Motzny, C. K., and Holmgren, R. (1995). The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways. Mech. Dev. 52, 137-150.
-
(1995)
Mech. Dev.
, vol.52
, pp. 137-150
-
-
Motzny, C.K.1
Holmgren, R.2
-
41
-
-
0035853040
-
Circularly permuted green fluorescent proteins engineered to sense Ca2+
-
USA
-
Nagai, T., Sawano, A., Park, E. S., and Miyawaki, A. (2001). Circularly permuted green fluorescent proteins engineered to sense Ca2+. Proc. Natl. Acad. Sci. USA 98, 3197-3202.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 3197-3202
-
-
Nagai, T.1
Sawano, A.2
Park, E.S.3
Miyawaki, A.4
-
42
-
-
70349771959
-
Dynamic interpretation of hedgehog signaling in the Drosophila wing disc
-
Nahmad, M., and Stathopoulos, A. (2009). Dynamic interpretation of hedgehog signaling in the Drosophila wing disc. PLoS Biol. 7, e1000202.
-
(2009)
PLoS Biol.
, vol.7
-
-
Nahmad, M.1
Stathopoulos, A.2
-
43
-
-
1142289021
-
Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila
-
Nakano, Y., Nystedt, S., Shivdasani, A. A., Strutt, H., Thomas, C., and Ingham, P. W. (2004). Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila. Mech. Dev. 121, 507-518.
-
(2004)
Mech. Dev.
, vol.121
, pp. 507-518
-
-
Nakano, Y.1
Nystedt, S.2
Shivdasani, A.A.3
Strutt, H.4
Thomas, C.5
Ingham, P.W.6
-
44
-
-
0008125299
-
Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster
-
Nüsslein-Volhard, C., Wieschaus, E., and Kluding, H. (1984). Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. 1. Zygotic loci on the second chromosome. Wilhelm Roux's Archives of Developmental Biology 193, 267-282.
-
(1984)
1. Zygotic loci on the second chromosome. Wilhelm Roux's Archives of Developmental Biology
, vol.193
, pp. 267-282
-
-
Nüsslein-Volhard, C.1
Wieschaus, E.2
Kluding, H.3
-
45
-
-
0242625184
-
Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2
-
Ogden, S. K., Ascano, M., Jr, Stegman, M. A., Suber, L. M., Hooper, J. E., and Robbins, D. J. (2003). Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2. Curr. Biol. 13, 1998-2003.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1998-2003
-
-
Ogden, S.K.1
Ascano, M.2
Stegman, Jr.M.A.3
Suber, L.M.4
Hooper, J.E.5
Robbins, D.J.6
-
46
-
-
57049085407
-
G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling
-
Ogden, S. K., Fei, D. L., Schilling, N. S., Ahmed, Y. F., Hwa, J., and Robbins, D. J. (2008). G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling. Nature 456, 967-970.
-
(2008)
Nature
, vol.456
, pp. 967-970
-
-
Ogden, S.K.1
Fei, D.L.2
Schilling, N.S.3
Ahmed, Y.F.4
Hwa, J.5
Robbins, D.J.6
-
47
-
-
0024964973
-
Expression of engrailed proteins in arthropods, annelids, and chordates
-
Patel, N. H., Martin-Blanco, E., Coleman, K. G., Poole, S. J., Ellis, M. C., Kornberg, T. B., and Goodman, C. S. (1989). Expression of engrailed proteins in arthropods, annelids, and chordates. Cell 58, 955-968.
-
(1989)
Cell
, vol.58
, pp. 955-968
-
-
Patel, N.H.1
Martin-Blanco, E.2
Coleman, K.G.3
Poole, S.J.4
Ellis, M.C.5
Kornberg, T.B.6
Goodman, C.S.7
-
48
-
-
73349130440
-
Drosophila genomewide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate
-
Pospisilik, J. A., Schramek, D., Schnidar, H., Cronin, S. J., Nehme, N. T., Zhang, X., Knauf, C., Cani, P. D., Aumayr, K., Todoric, J. et al. (2010). Drosophila genomewide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell 140, 148-160.
-
(2010)
Cell
, vol.140
, pp. 148-160
-
-
Pospisilik, J.A.1
Schramek, D.2
Schnidar, H.3
Cronin, S.J.4
Nehme, N.T.5
Zhang, X.6
Knauf, C.7
Cani, P.D.8
Aumayr, K.9
Todoric, J.10
-
49
-
-
69949106280
-
Lateral diffusion of membrane proteins
-
Ramadurai, S., Holt, A., Krasnikov, V., van den Bogaart, G., Killian, J. A., and Poolman, B. (2009). Lateral diffusion of membrane proteins. J. Am. Chem. Soc. 131, 12650-12656.
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 12650-12656
-
-
Ramadurai, S.1
Holt, A.2
Krasnikov, V.3
van den Bogaart, G.4
Killian, J.A.5
Poolman, B.6
-
50
-
-
84877101725
-
Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction
-
Shi, D., Lv, X., Zhang, Z., Yang, X., Zhou, Z., Zhang, L., and Zhao, Y. (2013). Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction. J. Biol. Chem. 288, 12605-12614.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 12605-12614
-
-
Shi, D.1
Lv, X.2
Zhang, Z.3
Yang, X.4
Zhou, Z.5
Zhang, L.6
Zhao, Y.7
-
51
-
-
79960084157
-
Sequential phosphorylation of smoothened transduces graded hedgehog signaling
-
Su, Y., Ospina, J. K., Zhang, J., Michelson, A. P., Schoen, A. M., and Zhu, A. J. (2011). Sequential phosphorylation of smoothened transduces graded hedgehog signaling. Sci. Signal. 4, ra43.
-
(2011)
Sci. Signal.
, vol.4
-
-
Su, Y.1
Ospina, J.K.2
Zhang, J.3
Michelson, A.P.4
Schoen, A.M.5
Zhu, A.J.6
-
52
-
-
0037158748
-
Patched acts catalytically to suppress the activity of Smoothened
-
Taipale, J., Cooper, M. K., Maiti, T., and Beachy, P. A. (2002). Patched acts catalytically to suppress the activity of Smoothened. Nature 418, 892-897.
-
(2002)
Nature
, vol.418
, pp. 892-897
-
-
Taipale, J.1
Cooper, M.K.2
Maiti, T.3
Beachy, P.A.4
-
53
-
-
23444443064
-
Mechanisms of Hedgehog gradient formation and interpretation
-
Torroja, C., Gorfinkiel, N., and Guerrero, I. (2005). Mechanisms of Hedgehog gradient formation and interpretation. J. Neurobiol. 64, 334-356. van den Heuvel, M., and Ingham, P. W. (1996). smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature 382, 547-551.
-
(2005)
J. Neurobiol.
, vol.64
, pp. 334-356
-
-
Torroja, C.1
Gorfinkiel, N.2
Guerrero, I.3
-
54
-
-
0029784223
-
smoothened encodes a receptor-like serpentine protein required for hedgehog signalling
-
van den Heuvel, M., and Ingham, P. W. (1996). smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature 382, 547-551.
-
(1996)
Nature
, vol.382
, pp. 547-551
-
-
van den Heuvel, M.1
Ingham, P.W.2
-
55
-
-
79952260055
-
Dynamics of Dpp signaling and proliferation control
-
Wartlick, O., Mumcu, P., Kicheva, A., Bittig, T., Seum, C., Jülicher, F., and González-Gaitán, M. (2011). Dynamics of Dpp signaling and proliferation control. Science 331, 1154-1159.
-
(2011)
Science
, vol.331
, pp. 1154-1159
-
-
Wartlick, O.1
Mumcu, P.2
Kicheva, A.3
Bittig, T.4
Seum, C.5
Jülicher, F.6
González-Gaitán, M.7
-
56
-
-
0036106455
-
Analysis of ligand binding by two-colour fluorescence cross-correlation spectroscopy
-
Weidemann, T., Wachsmuth, M., Tewes, M., Rippe, K., and Langowski, J. (2002). Analysis of ligand binding by two-colour fluorescence cross-correlation spectroscopy. Single Mol. 3, 49-61.
-
(2002)
Single Mol.
, vol.3
, pp. 49-61
-
-
Weidemann, T.1
Wachsmuth, M.2
Tewes, M.3
Rippe, K.4
Langowski, J.5
-
57
-
-
81255164768
-
Single cell analysis of ligand binding and complex formation of interleukin-4 receptor subunits
-
Weidemann, T., Worch, R., Kurgonaite, K., Hintersteiner, M., Bökel, C., and Schwille, P. (2011). Single cell analysis of ligand binding and complex formation of interleukin-4 receptor subunits. Biophys. J. 101, 2360-2369.
-
(2011)
Biophys. J.
, vol.101
, pp. 2360-2369
-
-
Weidemann, T.1
Worch, R.2
Kurgonaite, K.3
Hintersteiner, M.4
Bökel, C.5
Schwille, P.6
-
58
-
-
10044253425
-
AKAP signalling complexes: focal points in space and time
-
Wong, W., and Scott, J. D. (2004). AKAP signalling complexes: focal points in space and time. Nat. Rev. Mol. Cell Biol. 5, 959-970.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 959-970
-
-
Wong, W.1
Scott, J.D.2
-
59
-
-
78649668571
-
Focus on composition and interaction potential of single-pass transmembrane domains
-
Worch, R., Bökel, C., Höfinger, S., Schwille, P., and Weidemann, T. (2010). Focus on composition and interaction potential of single-pass transmembrane domains. Proteomics 10, 4196-4208.
-
(2010)
Proteomics
, vol.10
, pp. 4196-4208
-
-
Worch, R.1
Bökel, C.2
Höfinger, S.3
Schwille, P.4
Weidemann, T.5
-
60
-
-
84863012620
-
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization
-
Xia, R., Jia, H., Fan, J., Liu, Y., and Jia, J. (2012). USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization. PLoS Biol. 10, e1001238.
-
(2012)
PLoS Biol.
, vol.10
-
-
Xia, R.1
Jia, H.2
Fan, J.3
Liu, Y.4
Jia, J.5
-
61
-
-
77954949822
-
Role of lipid metabolism in smoothened derepression in hedgehog signaling
-
Yavari, A., Nagaraj, R., Owusu-Ansah, E., Folick, A., Ngo, K., Hillman, T., Call, G., Rohatgi, R., Scott, M. P., and Banerjee, U. (2010). Role of lipid metabolism in smoothened derepression in hedgehog signaling. Dev. Cell 19, 54-65.
-
(2010)
Dev. Cell
, vol.19
, pp. 54-65
-
-
Yavari, A.1
Nagaraj, R.2
Owusu-Ansah, E.3
Folick, A.4
Ngo, K.5
Hillman, T.6
Call, G.7
Rohatgi, R.8
Scott, M.P.9
Banerjee, U.10
-
62
-
-
11144248964
-
Extensive phosphorylation of Smoothened in Hedgehog pathway activation
-
USA
-
Zhang, C., Williams, E. H., Guo, Y., Lum, L., and Beachy, P. A. (2004). Extensive phosphorylation of Smoothened in Hedgehog pathway activation. Proc. Natl. Acad. Sci. USA 101, 17900-17907.
-
(2004)
Proc. Natl. Acad. Sci.
, vol.101
, pp. 17900-17907
-
-
Zhang, C.1
Williams, E.H.2
Guo, Y.3
Lum, L.4
Beachy, P.A.5
-
63
-
-
36049033946
-
Hedgehog regulates smoothened activity by inducing a conformational switch
-
Zhao, Y., Tong, C., and Jiang, J. (2007). Hedgehog regulates smoothened activity by inducing a conformational switch. Nature 450, 252-258.
-
(2007)
Nature
, vol.450
, pp. 252-258
-
-
Zhao, Y.1
Tong, C.2
Jiang, J.3
-
64
-
-
73549083198
-
Genetic and biochemical definition of the Hedgehog receptor
-
Zheng, X., Mann, R. K., Sever, N., and Beachy, P. A. (2010). Genetic and biochemical definition of the Hedgehog receptor. Genes Dev. 24, 57-71.
-
(2010)
Genes Dev.
, vol.24
, pp. 57-71
-
-
Zheng, X.1
Mann, R.K.2
Sever, N.3
Beachy, P.A.4
-
65
-
-
0038625111
-
Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction
-
Zhu, A. J., Zheng, L., Suyama, K., and Scott, M. P. (2003). Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction. Genes Dev. 17, 1240-1252.
-
(2003)
Genes Dev.
, vol.17
, pp. 1240-1252
-
-
Zhu, A.J.1
Zheng, L.2
Suyama, K.3
Scott, M.P.4
|