Altered Cardiac Electrophysiology and SUDEP in a Model of Dravet Syndrome

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Auerbach, David S ^a   Jones, Julie ^a   Clawson, Brittany C ^a   Offord, James ^a   Lenk, Guy M ^a   Ogiwara, Ikuo ^c   Yamakawa, Kazuhiro ^c   Meisler, Miriam H ^a   Parent, Jack M ^a,b   Isom, Lori L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; SODIUM CHANNEL NAV1.1; TETRODOTOXIN;

ANIMAL CELL; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYCARDIA; DYING; ELECTROCARDIOGRAPHY; FEMALE; HEART BEAT; HEART ELECTROPHYSIOLOGY; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HEART VENTRICLE WALL; HETEROZYGOSITY; IN VIVO STUDY; MALE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; QT PROLONGATION; SEVERE MYOCLONIC EPILEPSY IN INFANCY; SODIUM CURRENT; SUDDEN CARDIAC DEATH; TELEMETRY;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; CARDIAC ELECTROPHYSIOLOGY; DEATH, SUDDEN, CARDIAC; DISEASE MODELS, ANIMAL; EPILEPSIES, MYOCLONIC; HEART RATE; HUMANS; ION CHANNEL GATING; MICE; MICE, INBRED C57BL; MUTATION; MYOCYTES, CARDIAC; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PENTYLENETETRAZOLE; PROTEIN BIOSYNTHESIS; TELEMETRY; TETRODOTOXIN; TRANSCRIPTION, GENETIC;

EID: 84885408858     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077843     Document Type: Article

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