-
1
-
-
0025935591
-
The long QT syndrome: Prospective longitudinal study of 328 families
-
Moss, A.J., et al. 1991. The long QT syndrome: prospective longitudinal study of 328 families. Circulation. 84:1136-1144.
-
(1991)
Circulation
, vol.84
, pp. 1136-1144
-
-
Moss, A.J.1
-
2
-
-
0031283352
-
Molecular physiology of cardiac delayed rectifier K+ channels
-
Sanguinetti, M.C., and Zou, A. 1997. Molecular physiology of cardiac delayed rectifier K+ channels [review]. Heart Vessels. 12(Suppl.):170-172.
-
(1997)
Heart Vessels
, vol.12
, Issue.SUPPL.
, pp. 170-172
-
-
Sanguinetti, M.C.1
Zou, A.2
-
3
-
-
0029097799
-
Molecular mechanism for an inherited cardiac arrhythmia
-
Bennett, P.B., Yazawa, K., Makita, N., and George, A.L. 1995. Molecular mechanism for an inherited cardiac arrhythmia. Nature. 376:683-685.
-
(1995)
Nature
, vol.376
, pp. 683-685
-
-
Bennett, P.B.1
Yazawa, K.2
Makita, N.3
George, A.L.4
-
4
-
-
49749174698
-
Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval and sudden death
-
Jervell, A., and Lange-Nielsen, F. 1957. Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval and sudden death. Am. Heart J. 54:59-68.
-
(1957)
Am. Heart J.
, vol.54
, pp. 59-68
-
-
Jervell, A.1
Lange-Nielsen, F.2
-
5
-
-
0030918946
-
Molecular basis of the long-QT syndrome associated with deafness
-
Splawski, I., Timothy, K.W., Vincent, G.M., Atkinson, D.L., and Keating, M.T. 1997. Molecular basis of the long-QT syndrome associated with deafness. N. Engl. J. Med. 336:1562-1567.
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1562-1567
-
-
Splawski, I.1
Timothy, K.W.2
Vincent, G.M.3
Atkinson, D.L.4
Keating, M.T.5
-
6
-
-
0034609531
-
Spectrum of mutations in long-QT syndrome genes: KVLQT1, HERG, SCN5A, KCNE1, and KCNE2
-
Splawski, I., et al. 2000. Spectrum of mutations in long-QT syndrome genes: KVLQT1, HERG, SCN5A, KCNE1, and KCNE2. Circulation. 102:1178-1185.
-
(2000)
Circulation
, vol.102
, pp. 1178-1185
-
-
Splawski, I.1
-
7
-
-
0037851905
-
Long QT syndrome
-
Moss, A.J. 2003. Long QT syndrome. JAMA. 289:2041-2044.
-
(2003)
JAMA
, vol.289
, pp. 2041-2044
-
-
Moss, A.J.1
-
8
-
-
0030832290
-
Molecular biology of the long QT syndrome: Impact on management
-
Priori, S.G., Napolitano, C., Paganini, V., Cantu, F., and Schwartz, P.J. 1997. Molecular biology of the long QT syndrome: impact on management. Pacing Clin. Electrophysiol. 20:2052-2057.
-
(1997)
Pacing Clin. Electrophysiol.
, vol.20
, pp. 2052-2057
-
-
Priori, S.G.1
Napolitano, C.2
Paganini, V.3
Cantu, F.4
Schwartz, P.J.5
-
9
-
-
0032189139
-
Influence of genotype on the clinical course of the long-QT syndrome
-
International Long-QT Syndrome Registry Research Group
-
Zareba, W., et al. 1998. Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group. N. Engl. J. Med. 339:960-965.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 960-965
-
-
Zareba, W.1
-
10
-
-
0035830365
-
Genotype-phenotype correlation in the long-QT syndrome: Gene-specific triggers for life-threatening arrhythmias
-
Schwartz, P.J., et al. 2001. Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation. 103:89-95.
-
(2001)
Circulation
, vol.103
, pp. 89-95
-
-
Schwartz, P.J.1
-
11
-
-
0036237833
-
Epinephrine-induced QT interval prolongation: A gene-specific paradoxical response in congenital long QT syndrome
-
Ackerman, M.J., et al. 2002. Epinephrine-induced QT interval prolongation: a gene-specific paradoxical response in congenital long QT syndrome. Mayo Clin. Proc. 77:413-421.
-
(2002)
Mayo Clin. Proc.
, vol.77
, pp. 413-421
-
-
Ackerman, M.J.1
-
12
-
-
0037448805
-
Exercise stress test amplifies genotype-phenotype correlation in the LQT1 and LQT2 forms of the long-QT syndrome
-
Takenaka, K., et al. 2003. Exercise stress test amplifies genotype-phenotype correlation in the LQT1 and LQT2 forms of the long-QT syndrome. Circulation. 107:838-844.
-
(2003)
Circulation
, vol.107
, pp. 838-844
-
-
Takenaka, K.1
-
13
-
-
0034768334
-
Response of the QT interval to mental and physical stress in types LQT1 and LQT2 of the long QT syndrome
-
Paavonen, K.J., et al. 2001. Response of the QT interval to mental and physical stress in types LQT1 and LQT2 of the long QT syndrome. Heart. 86:39-44.
-
(2001)
Heart
, vol.86
, pp. 39-44
-
-
Paavonen, K.J.1
-
14
-
-
17044446589
-
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome
-
Moss, A.J., et al. 2000. Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome. Circulation. 101:616-623.
-
(2000)
Circulation
, vol.101
, pp. 616-623
-
-
Moss, A.J.1
-
15
-
-
4544387969
-
Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers
-
Priori, S.G., et al. 2004. Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers. JAMA 292:1341-1344.
-
(2004)
JAMA
, vol.292
, pp. 1341-1344
-
-
Priori, S.G.1
-
16
-
-
0028908741
-
Assignment of the human heart tetrodotoxin-resistant voltage-gated Na+ channel alpha-subunit gene (SCN5A) to band 3P21
-
George, A.L., et al. 1995. Assignment of the human heart tetrodotoxin-resistant voltage-gated Na+ channel alpha-subunit gene (SCN5A) to band 3P21. Cytogenet. Cell Genet. 68:67-70.
-
(1995)
Cytogenet. Cell Genet.
, vol.68
, pp. 67-70
-
-
George, A.L.1
-
17
-
-
0028905566
-
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
-
Wang, Q., et al. 1995. SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell. 80:805-811.
-
(1995)
Cell
, vol.80
, pp. 805-811
-
-
Wang, Q.1
-
18
-
-
0029116230
-
Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia
-
Wang, Q., et al. 1995. Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia. Hum. Mol. Genet. 4:1603-1607.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 1603-1607
-
-
Wang, Q.1
-
19
-
-
0034702931
-
Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome
-
Abrief H., Wehrens, X.H., Benhorin, J., Kerem, B., and Kass, R.S. 2000. Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome. Circulation. 102:921-925.
-
(2000)
Circulation
, vol.102
, pp. 921-925
-
-
Abrief, H.1
Wehrens, X.H.2
Benhorin, J.3
Kerem, B.4
Kass, R.S.5
-
20
-
-
0034640093
-
Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel
-
Veldkamp, M.W., et al. 2000. Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel. Circ. Res. 86:E91-E97.
-
(2000)
Circ. Res.
, vol.86
-
-
Veldkamp, M.W.1
-
21
-
-
0028874658
-
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to NA+ channel blockade and to increases in heart rate: Implications for gene-specific therapy
-
Schwartz, P.J., et al. 1995. Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to NA+ channel blockade and to increases in heart rate: implications for gene-specific therapy. Circulation. 92:3381-3386.
-
(1995)
Circulation
, vol.92
, pp. 3381-3386
-
-
Schwartz, P.J.1
-
22
-
-
0030791119
-
Gene-specific therapy for long QT syndrome: QT shortening with lidocaine and tocainide in patients with mutation of the sodium channel gene
-
Rosero, S.Z., Zareba, W., Robinson, J.L., and Moss, A. 1997. Gene-specific therapy for long QT syndrome: QT shortening with lidocaine and tocainide in patients with mutation of the sodium channel gene. Ann. Noninvasive Electrocardiol. 2:274-278.
-
(1997)
Ann. Noninvasive Electrocardiol.
, vol.2
, pp. 274-278
-
-
Rosero, S.Z.1
Zareba, W.2
Robinson, J.L.3
Moss, A.4
-
23
-
-
0035022511
-
Normalization of ventricular repolarization with flecainide m long QT syndrome patients with SCN5A:DeltaKPQ mutation
-
Windle, J.R., Geletka, R.C., Moss, A.J., Zareba, W., and Atkins, D.L. 2001. Normalization of ventricular repolarization with flecainide m long QT syndrome patients with SCN5A:DeltaKPQ mutation. Ann. Noninvasive Electrocardiol. 6:153-158.
-
(2001)
Ann. Noninvasive Electrocardiol.
, vol.6
, pp. 153-158
-
-
Windle, J.R.1
Geletka, R.C.2
Moss, A.J.3
Zareba, W.4
Atkins, D.L.5
-
24
-
-
0034636115
-
Effects of flecainide in patients with new SCN5A mutation: Mutation-specific therapy for long-QT syndrome?
-
Benhorin, J., et al. 2000. Effects of flecainide in patients with new SCN5A mutation: mutation-specific therapy for long-QT syndrome? Circulation. 101:1698-1706.
-
(2000)
Circulation
, vol.101
, pp. 1698-1706
-
-
Benhorin, J.1
-
25
-
-
0033982867
-
Preferential block of late sodium current in the LQT3 DeltaKPQ mutant by the class I(C) antiarrhythmic flecainide
-
Nagatomo, T., January, C.T., and Makielski, J.C. 2000. Preferential block of late sodium current in the LQT3 DeltaKPQ mutant by the class I(C) antiarrhythmic flecainide. Mol. Pharmacol. 57:101-107.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 101-107
-
-
Nagatomo, T.1
January, C.T.2
Makielski, J.C.3
-
26
-
-
0034546344
-
Long QT syndrome: Cellular basis and arrhythmia mechanism in LQT2
-
January, C.T., Gong, Q., and Zhou, Z. 2000. Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2. J. Cardiovasc. Electrophysiol. 11:1413-1418.
-
(2000)
J. Cardiovasc. Electrophysiol.
, vol.11
, pp. 1413-1418
-
-
January, C.T.1
Gong, Q.2
Zhou, Z.3
-
27
-
-
0029925480
-
Spectrum of HERG K channel dysfunction in an inherited cardiac arrhythmia
-
Sanguinetti, M.C., Curran, M.E., Spector, P.S., and Keating, M.T. 1996. Spectrum of HERG K channel dysfunction in an inherited cardiac arrhythmia. Proc. Natl. Acad. Sci. U. S. A. 93:2208-2212.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 2208-2212
-
-
Sanguinetti, M.C.1
Curran, M.E.2
Spector, P.S.3
Keating, M.T.4
-
28
-
-
0037133307
-
Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel
-
Moss, A.J., et al. 2002. Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel. Circulation. 105:794-799.
-
(2002)
Circulation
, vol.105
, pp. 794-799
-
-
Moss, A.J.1
-
29
-
-
10744231816
-
Location of mutation in the KCNQ1 and phenotypic presentation of long QT syndrome
-
Zareba, W., et al. 2003. Location of mutation in the KCNQ1 and phenotypic presentation of long QT syndrome. J. Cardiovasc. Electrophysiol. 14:1149-1153.
-
(2003)
J. Cardiovasc. Electrophysiol.
, vol.14
, pp. 1149-1153
-
-
Zareba, W.1
-
30
-
-
3242752714
-
Mutation site-specific differences in arrhythmic risk and sensitivity to sympathetic stimulation in the LQT1 form of congenital long QT syndrome: Multicenter study in Japan
-
Shimizu, W., et al. 2004. Mutation site-specific differences in arrhythmic risk and sensitivity to sympathetic stimulation in the LQT1 form of congenital long QT syndrome: multicenter study in Japan. J. Am. Coll. Cardiol. 44:117-125.
-
(2004)
J. Am. Coll. Cardiol.
, vol.44
, pp. 117-125
-
-
Shimizu, W.1
-
31
-
-
0014266238
-
The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres
-
Noble, D., and Tsien, R. 1968. The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres. J. Physiol. 195:185-214.
-
(1968)
J. Physiol.
, vol.195
, pp. 185-214
-
-
Noble, D.1
Tsien, R.2
-
32
-
-
0014438985
-
Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres
-
Noble, D., and Tsien, R.W. 1969. Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres. J. Physiol. 200:205-231.
-
(1969)
J. Physiol.
, vol.200
, pp. 205-231
-
-
Noble, D.1
Tsien, R.W.2
-
33
-
-
0025351245
-
Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents
-
Sanguinetti, M.C., and Jurkiewicz, N.K. 1990. Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents. J. Gen. Physiol. 96:195-215.
-
(1990)
J. Gen. Physiol.
, vol.96
, pp. 195-215
-
-
Sanguinetti, M.C.1
Jurkiewicz, N.K.2
-
34
-
-
0020003884
-
The ionic basis of concent ration-related effects of noradrenaline on the action potential of calf cardiac purkinje fibres
-
Kass, R.S., and Wiegers, S.E. 1982. The ionic basis of concent ration-related effects of noradrenaline on the action potential of calf cardiac purkinje fibres. J. Physiol. 322:541-558.
-
(1982)
J. Physiol.
, vol.322
, pp. 541-558
-
-
Kass, R.S.1
Wiegers, S.E.2
-
35
-
-
0029002969
-
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
-
Sanguinetti, M.C., Jiang, C., Curran, M.E., and Keating, M.T. 1995. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell. 81:299-307.
-
(1995)
Cell
, vol.81
, pp. 299-307
-
-
Sanguinetti, M.C.1
Jiang, C.2
Curran, M.E.3
Keating, M.T.4
-
36
-
-
0034710933
-
A structural basis for drug-induced long QT syndrome
-
Mitcheson, J.S., Chen, J., Lin, M., Culberson, C., and Sanguinetti, M.C. 2000. A structural basis for drug-induced long QT syndrome. Proc. Natl. Acad. Sci. U. S. A. 97:12329-12333.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 12329-12333
-
-
Mitcheson, J.S.1
Chen, J.2
Lin, M.3
Culberson, C.4
Sanguinetti, M.C.5
-
37
-
-
9044240040
-
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias
-
Wang, Q., et al. 1996. Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat. Genet. 12:17-23.
-
(1996)
Nat. Genet.
, vol.12
, pp. 17-23
-
-
Wang, Q.1
-
38
-
-
0029854263
-
Coassembly of KvLQT1 and minK(ISK) proteins to form cardiac IKS potassium channel
-
Sanguinetti, M.C., et al. 1996. Coassembly of KvLQT1 and minK(ISK) proteins to form cardiac IKS potassium channel. Nature. 384:80-83.
-
(1996)
Nature
, vol.384
, pp. 80-83
-
-
Sanguinetti, M.C.1
-
39
-
-
0029952101
-
K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
-
Barhanin, J., et al. 1996. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature. 384:78-80.
-
(1996)
Nature
, vol.384
, pp. 78-80
-
-
Barhanin, J.1
-
40
-
-
0030723260
-
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
-
Splawski, I., Tristani-Firouzi, M., Lehmann, M.H., Sanguinetti, M.C., and Keating, M.T. 1997. Mutations in the hminK gene cause long QT syndrome and suppress IKs function. Nat. Genet. 17:338-340.
-
(1997)
Nat. Genet.
, vol.17
, pp. 338-340
-
-
Splawski, I.1
Tristani-Firouzi, M.2
Lehmann, M.H.3
Sanguinetti, M.C.4
Keating, M.T.5
-
41
-
-
0037127028
-
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel
-
Marx, S.O., et al. 2002. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science. 295:496-499.
-
(2002)
Science
, vol.295
, pp. 496-499
-
-
Marx, S.O.1
-
42
-
-
0037452722
-
Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel
-
Kurokawa, J., Chen, L., and Kass, R.S. 2003. Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel. Proc. Natl. Acad. Sci. U. S. A. 100:2122-2127.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 2122-2127
-
-
Kurokawa, J.1
Chen, L.2
Kass, R.S.3
-
43
-
-
85047689493
-
Long QT syndrome: Novel insights into the mechanisms of cardiac arrhythmias
-
doi:10.1172/JCI200319844
-
Kass, R.S., and Moss, A.J. 2003. Long QT syndrome: novel insights into the mechanisms of cardiac arrhythmias. J. Clin. Invest. 112:810-815. doi:10.1172/JCI200319844.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 810-815
-
-
Kass, R.S.1
Moss, A.J.2
-
44
-
-
0032903775
-
Novel mechanism associated with an inherited cardiac arrhythmia: Defective protein trafficking by the mutant HERG (G601S) potassium channel
-
Furutani, M., et al. 1999. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel. Circulation. 99:2290-2294.
-
(1999)
Circulation
, vol.99
, pp. 2290-2294
-
-
Furutani, M.1
-
45
-
-
0033615646
-
Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects
-
Zhou, Z., Gong, Q., and January, C.T. 1999. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects. J. Biol. Chem. 274:31123-31126.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31123-31126
-
-
Zhou, Z.1
Gong, Q.2
January, C.T.3
-
46
-
-
0037085464
-
The binding site for channel blockers chac rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations
-
Picker, E., Obejero-Paz, C.A., Zhao, S., and Brown, A.M. 2002. The binding site for channel blockers chac rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations. J. Biol. Chem. 277:4989-4998.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4989-4998
-
-
Picker, E.1
Obejero-Paz, C.A.2
Zhao, S.3
Brown, A.M.4
-
47
-
-
2242423606
-
A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency
-
Paulussen, A., et al. 2002. A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency. J. Biol. Chem. 277:48610-48616.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48610-48616
-
-
Paulussen, A.1
-
48
-
-
0037129911
-
Pharmacological rescue of human K(+) channel long-QT2 mutations: Human ether-a-go-go-related gene rescue without block
-
Rajamani, S., Anderson, C.L., Anson, B.D., and January, C.T. 2002. Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block. Circulation. 105:2830-2835.
-
(2002)
Circulation
, vol.105
, pp. 2830-2835
-
-
Rajamani, S.1
Anderson, C.L.2
Anson, B.D.3
January, C.T.4
-
49
-
-
3242717751
-
Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits
-
Gong, Q., Anderson, C.L., January, C.T., and Zhou, Z. 2004. Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits. Am. J. Physiol. Heart Circ. Physiol. 287:H652-H658.
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.287
-
-
Gong, Q.1
Anderson, C.L.2
January, C.T.3
Zhou, Z.4
-
50
-
-
0024368695
-
Structural parts involved in activation and inactivation of the sodium channel
-
Stuhmer, W., et al. 1989. Structural parts involved in activation and inactivation of the sodium channel. Nature. 339:597-603.
-
(1989)
Nature
, vol.339
, pp. 597-603
-
-
Stuhmer, W.1
-
51
-
-
0029026638
-
Structure and function of voltage-gated ion channels
-
Catterall, W.A. 1995. Structure and function of voltage-gated ion channels [review]. Annu. Rev. Biochem. 64:493-531.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 493-531
-
-
Catterall, W.A.1
-
52
-
-
0001376159
-
The electrical constants of Purkinje fibres
-
Weidmann, S. 1952. The electrical constants of Purkinje fibres. J. Physiol. 118:348-360.
-
(1952)
J. Physiol.
, vol.118
, pp. 348-360
-
-
Weidmann, S.1
-
53
-
-
0842326191
-
The Na+ channel inactivation gate is a molecular complex: A novel role of the COOH-terminal domain
-
Motoike, H.K., et al. 2004. The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain. J. Gen. Physiol. 123:155-165.
-
(2004)
J. Gen. Physiol.
, vol.123
, pp. 155-165
-
-
Motoike, H.K.1
-
54
-
-
7244254394
-
Calmodulin mediates Ca2+ sensitivity of sodium channels
-
Kim, J., et al. 2004. Calmodulin mediates Ca2+ sensitivity of sodium channels. J. Biol. Chem. 279:45004-45012.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45004-45012
-
-
Kim, J.1
-
55
-
-
2442682788
-
Andersen-Tawil syndrome: A model of clinical variability, pleiotropy, and genetic heterogeneity
-
Donaldson, M.R., Yoon, G., Fu, Y.H., and Ptacek, L.J. 2004. Andersen-Tawil syndrome: a model of clinical variability, pleiotropy, and genetic heterogeneity. Ann. Med. 36(Suppl. 1):92-97.
-
(2004)
Ann. Med.
, vol.36
, Issue.SUPPL. 1
, pp. 92-97
-
-
Donaldson, M.R.1
Yoon, G.2
Fu, Y.H.3
Ptacek, L.J.4
-
56
-
-
0036724842
-
KCNJ2 mutation results in Andersen syndrome with sex-specific cardiac and skeletal muscle phenotypes
-
Andelfinger, G., et al. 2002. KCNJ2 mutation results in Andersen syndrome with sex-specific cardiac and skeletal muscle phenotypes. Am. J. Hum. Genet. 71:663-668.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 663-668
-
-
Andelfinger, G.1
-
57
-
-
0036324229
-
Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)
-
doi:10.1172/JCI200215183
-
Tristani-Firouzi, M., et al. 2002. Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome). J. Clin. Invest. 110:381-388. doi:10.1172/JCI200215183.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 381-388
-
-
Tristani-Firouzi, M.1
-
58
-
-
0347064347
-
Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome
-
Bendahhou, S., et al. 2003. Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome. J. Biol. Chem. 278:51779-51785.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51779-51785
-
-
Bendahhou, S.1
-
59
-
-
5344223383
-
Ca(V) 1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
-
Splawski, I., et al. 2004. Ca(V) 1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell. 119:19-31.
-
(2004)
Cell
, vol.119
, pp. 19-31
-
-
Splawski, I.1
-
60
-
-
0021677187
-
Calcium channel in activation in the cardiac Purkinje fiber. Evidence for voltage- and calcium-mediated mechanisms
-
Kass, R.S., and Sanguinetti, M.C. 1984. Calcium channel in activation in the cardiac Purkinje fiber. Evidence for voltage- and calcium-mediated mechanisms. J. Gen. Physiol. 84:705-726.
-
(1984)
J. Gen. Physiol.
, vol.84
, pp. 705-726
-
-
Kass, R.S.1
Sanguinetti, M.C.2
-
61
-
-
0028819671
-
Mapping of a gene for long QT syndrome to chromosome 4q25-27
-
Schote, J.J., et al. 1995. Mapping of a gene for long QT syndrome to chromosome 4q25-27. Am. J. Hum. Genet. 57:1114-1122.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 1114-1122
-
-
Schote, J.J.1
-
62
-
-
0034599086
-
Abnormal cardiac Na(+) channel properties and QT heart rate adaptation in neonatal ankyrin(B) knockout mice
-
Chauhan, V.S., Tuvia, S., Buhusi, M., Bennett, V., and Grant, A.O. 2000. Abnormal cardiac Na(+) channel properties and QT heart rate adaptation in neonatal ankyrin(B) knockout mice. Circ. Res. 86:441-447.
-
(2000)
Circ. Res.
, vol.86
, pp. 441-447
-
-
Chauhan, V.S.1
Tuvia, S.2
Buhusi, M.3
Bennett, V.4
Grant, A.O.5
-
63
-
-
2342597764
-
LQT4 gene: The "missing" ankytin
-
Yong, S., Tian, X., and Wang, Q. 2003. LQT4 gene: the "missing" ankytin. Mol. Interv. 3:131-136.
-
(2003)
Mol. Interv.
, vol.3
, pp. 131-136
-
-
Yong, S.1
Tian, X.2
Wang, Q.3
-
64
-
-
0242464931
-
Ankytin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
-
Mohler, P.J., et al. 2003. Ankytin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature. 421:634-639.
-
(2003)
Nature
, vol.421
, pp. 634-639
-
-
Mohler, P.J.1
-
65
-
-
2942695712
-
A cardiac arrhythmia syndrome caused by loss of ankyrin-B function
-
Mohler, P.J., et al. 2004. A cardiac arrhythmia syndrome caused by loss of ankyrin-B function. Proc. Natl. Acad. Sci. U. S. A. 101:9137-9142.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 9137-9142
-
-
Mohler, P.J.1
|